Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:2.7.11.24 (mitogen-activated protein kinase)
 95,810 document(s) hit in 31,850,051 MEDLINE articles (0.08 seconds) .

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Human Gene/Protein
Microtubule-associated protein 2 kinase 8.4
SSTK-interacting protein 8.4
Caspase recruitment domain-containing protein 14 8.4
FAM38A protein 8.4
C21orf34 8.4
RUN and FYVE domain containing 1 8.4
MAP kinase 8.4
ZNF394 protein 8.4
ZNF605 8.4
NMT2 protein 8.4
DOC1R 8.4
RhoGAP2 8.4
cell cycle exit and neuronal differentiation 1 8.4
UEVLD 8.4
LOC389473 8.4
MER receptor tyrosine kinase 8.4
NBPF10 8.4
Gab3 protein 8.4
FAM115C 8.4
AKAP9-BRAF fusion protein 8.4
TMEM109 8.4
OR9Q1 8.4
topoisomerase III beta 8.4
KDEL (Lys-Asp-Glu-Leu) containing 2 8.4
CRHSP24 8.4
KIAA1219 8.4
ADAM 32 8.4
CIITA IV 8.4
mitochondrial processing peptidase beta-subunit 8.4
hypothetical protein BC014241 8.4
Mst3 and SOK1-related kinase 8.4
Protein tyrosine phosphatase, non-receptor type 2 8.4
CRKRS 8.4
Protease, serine, 3 8.4
Parkinson disease (autosomal recessive, juvenile) 2, parkin 8.4
Ras-related protein Rab-34 8.4
ZNF480 8.4
WD repeat-containing protein 35 8.4
MEK partner 1 8.4
JNK 8.4
PLSCR5 8.4
peroxisomal biogenesis factor 3 8.4
C9orf16 8.4
ZAS2 8.4
ZNF446 protein 8.4
PI4KAP2 8.4
C13orf27 8.4
manic fringe homolog 8.4
Ras-like protein family member 11B 8.4
PLA2G16 protein 8.4
ILPIP 8.4
jumonji C domain containing histone demethylase 1 homolog D 8.4
ZNF434 8.4
HMP19 8.4
DNA replication licensing factor MCM5 8.4
Activator of G-protein signaling 4 8.4
ZNF394 8.4
FAM178A 8.4
FAM127B 8.4
ZNF328 8.4
VRK2 protein 8.4
guanine nucleotide-releasing factor 2 8.4
serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform 8.4
SMEK1 8.4
cyclic adenosine 3',5'-monophosphate response element binding protein 8.4
major facilitator superfamily domain containing 2 8.4
v-yes-1 Yamaguchi sarcoma viral related oncogene homolog 8.4
chromosome 7 open reading frame 41 8.4
Rho family guanine-nucleotide exchange factor 8.4
GCK family kinase 8.4
TF2D 8.4
OR5M11 8.4
ZAS1 8.4
KRTAP2-4 8.4
NRN1L 8.4
RRG1 8.4
FAM129B protein 8.4
ZNF569 protein 8.4
MARP3 8.4
RPS6KA6 protein 8.4
more...
Disease
Autoimmune hypoparathyroidism 8.4
TBDN 8.4
Histiocytic neoplasms 7.4
Acute renal failure due to ischemia 7.4
Recurrent pterygium 7.4
Papillary craniopharyngioma 7.4
cardiofaciocutaneous syndrome 7.3
RP27 6.8
GINGF3 6.8
Placental choriocarcinoma 6.8
Gastrointestinal motility disorder 6.8
MRX47 6.8
Acute eczema 6.8
Nutritional muscular dystrophy 6.8
Costello syndrome 6.6
Acute quadriplegic myopathy 6.4
Acute ulcerative colitis 6.4
Diffuse Astrocytoma 6.4
HPC3 6.4
NRC1 6.4
OASF 6.2
bronchial disorder 6.1
pediatric anaplastic astrocytoma 6.1
metastatic nasopharyngeal cancer 6.1
Retinal microaneurysms 6.1
Keratocystic Odontogenic Tumor 6.1
ADMD 6.1
Marfanoid hypermobility syndrome 6.1
Spastic ataxia 6.1
LEOPARD syndrome 5.9
Pilocytic astrocytoma 5.8
Femoral artery occlusion 5.8
Squamous Cell Cancer 5.8
L.mexicana 5.8
ECL cell carcinoid 5.8
MRX30 5.8
JIP 5.6
adult pilocytic astrocytoma 5.6
ARVD1 5.6
Adrenal carcinoma 5.6
Bladder hypertrophy 5.6
FGD3 5.6
Mucinous Neoplasm 5.6
Myxoid chondrosarcoma 5.6
T Cell Leukemia 5.6
Chronic iron overload 5.5
Gastrointestinal mucositis 5.5
Type A insulin resistance 5.4
Pleomorphic malignant fibrous histiocytoma 5.4
Malignant insulinoma 5.4
AD4 5.3
CNA1 5.3
CSCD 5.2
PCH4 5.2
Reovirus infection 5.2
phakoma 5.2
CMML-1 5.2
FGD1 5.2
CYLD 5.1
Anaplastic Astrocytoma 5.1
Progression of prostate cancer 5.1
Malignant Peripheral Nerve Sheath Tumor 5.1
Drug-induced myopathy 5.1
DMAT 5.0
CNS degenerative disease 4.9
MDD2 4.9
Multiple cancer 4.9
KCS2 4.9
HIV neuropathy 4.8
DSCR 4.8
WM1 4.7
salivary gland adenoid cystic carcinoma 4.7
AGS 4.7
Jaagsiekte 4.7
Unilateral renal artery stenosis 4.7
Euthyroid sick syndrome 4.7
PanIN-1 4.6
Pulmonary Langerhans cell histiocytosis 4.6
Renal interstitial fibrosis 4.6
SPH1 4.6
more...
Symptom
impaired body balance 6.1
Inflammatory pain 5.6
Thalamic pain 5.2
Incisional pain 5.1
SYMPTOMS 4.5
Mucosal hyperplasia 4.1
Ear swelling 4.0
Bladder distention 4.0
cardiovascular problem 3.9
skin damage 3.8
Scratch 3.8
Central post-stroke pain 3.6
Organ failure 3.4
Mechanical pain 3.3
Neuropathic pain 3.3
stomach cramps 2.8
scaly skin 2.5
Macula 2.5
female puberty 2.5
GI irritation 2.4
starvation 2.4
impaired motor coordination 2.4
hyperoxia 2.2
bladder pain 2.1
Behavioral symptoms 2.0
Motor dysfunction 2.0
delayed language development 2.0
functional recovery 1.8
Noise-induced hearing loss 1.7
memory loss 1.7
orofacial pain 1.6
despair 1.5
Visceral pain 1.5
ACHE 1.5
acute stress 1.5
cachexia 1.3
bone pain 1.3
Anoxia 1.3
dry skin 1.2
neurological disability 1.1
muscle cramps 0.9
dry eye 0.8
skin irritant 0.8
catarrh 0.8
bradypnea 0.7
fasciculation 0.6
loss of balance 0.6
disturbed balance 0.5
HSA 0.5
Halo 0.5
decreased appetite 0.5
collapse 0.4
rundown 0.4
respiratory distress 0.4
periorbital edema 0.4
male subfertility 0.3
microbial colonization 0.3
Decreased activity 0.3
swollen joints 0.3
menopausal symptoms 0.3
ataxic gait 0.3
hypothermia 0.3
pain 0.2
arthralgia 0.2
pelvic pain 0.2
splenomegaly 0.2
incoordination 0.2
bedwetting 0.2
exhaustion -0.0
cancer pain -0.0
skin irritation -0.1
prostration -0.2
analgesia -0.2
nasal congestion -0.2
eye pain -0.2
bradykinesia -0.2
seizures -0.3
dental pain -0.3
muscle stiffness -0.3
twitching -0.3
more...
Drug
Caprylic Acid 8.4
S-Adenosyl-L-Homocysteine 8.4
Fexaramine 8.4
Doramapimod 7.8
Gypsum fibrosum 7.4
Aicar 7.4
Xaliproden 7.4
Zanthoxylum fruit 6.8
Asiasarum root 6.8
Canertinib dihydrochloride 6.8
Atractylodes lancea rhizome 6.4
Quazinone 6.4
D-Aspartic Acid 6.4
Rosaprostol 6.4
Efipladib 6.4
4',5,7-Trihydroxyisoflavone 6.4
Fingolimod hydrochloride 6.3
Mubritinib 6.1
Mudanpi 6.1
Dioscorea rhizome 6.1
Montirelin 6.1
Scutellaria root 6.0
Ephedrine hydrochloride 5.8
Fudosteine 5.8
Lexatumumab 5.8
Ciglitazone 5.8
Rehmannia root 5.8
Epimedium herb 5.6
Benfotiamine 5.6
Purvalanol 5.4
MAP 5.4
Fenobam 5.4
Alexidine 5.4
Dimetapp 5.4
Olomoucine 5.2
Axokine 5.2
Safingol 5.2
7-Hydroxystaurosporine 5.2
Hymenialdisine 5.1
Zedoary 5.1
Mapatumumab 5.1
Tipifarnib 5.1
Gefitinib 5.0
Nexavar 5.0
Epigallocatechin 4.9
Amlexanox 4.9
Mofezolac 4.9
Tanespimycin 4.9
Sorafenib 4.8
Neotrofin 4.8
Alsterpaullone 4.8
Enisoprost 4.8
Lonafarnib 4.8
Vandetanib 4.7
3-Methyladenine 4.7
2-Methoxyestradiol 4.7
Arsenic trioxide 4.7
ROS 4.7
Azilect 4.6
Radicicol 4.6
Tarceva 4.6
Tykerb 4.6
Emodin 4.6
Fidarestat 4.6
Fidarestat 4.6
Myricetin 4.6
RAL 4.6
Mevastatin 4.5
Sesamol 4.5
TAK 4.5
Fulvestrant 4.5
Angiotensin II 4.5
K-252a 4.5
Platonin 4.5
Fasudil hydrochloride 4.5
Hpp 4.5
Alrestatin 4.4
Fangji 4.4
Romet 4.4
NVP 4.4
more...
Enzyme
mitogen-activated protein kinase 8.4
MEKK1 7.7
MEK 7.6
D-alanyl-D-alanine dipeptidase 6.8
beta4GalNAc-T3 6.8
inositol 3-kinase 6.4
MAP 6.4
phosphatidylinositol 3-kinase 6.3
STK13 6.2
NSY 6.1
glucuronosyltransferase I 6.1
phosphoinositide 3-kinase 6.0
ERK 5.9
phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase 5.8
calpain B 5.8
phosphatidylinositol-4,5-bisphosphate 3-kinase 5.7
D-dopachrome tautomerase 5.7
IKK 5.6
CLK1 5.5
sphingosine kinase 5.4
2-deoxyglucose-6-phosphate phosphatase 5.4
phosphatidylinositol 3-phosphate 5-kinase 5.4
protein kinase C 5.2
lysoplasmalogenase 5.2
eEF2 kinase 5.2
protein kinase 5.2
glycerol 3-phosphatase 5.1
caspase-3 5.0
caspase-9 5.0
GRK2 5.0
CaMKII 5.0
NADPH oxidase 5.0
GSK 5.0
GRK5 5.0
protein phosphatase 2A 4.9
NADPH oxidase 4.9
caspase-4 4.9
secologanin synthase 4.9
AMPK 4.9
caspase-8 4.9
caspase-4 4.9
farnesyltransferase 4.8
cathepsin K 4.8
caspase-7 4.8
PARP 4.8
caspase-7 4.8
AMP-activated protein kinase 4.7
PDK1 4.7
CEP 4.7
acylglycerol kinase 4.7
PTPase 4.6
cdc2 4.6
focal adhesion kinase 4.6
PKG 4.6
inositol phosphatase 4.6
HK3 4.6
phosphoacetylglucosamine mutase 4.6
alpha-1,3-glucan synthase 4.5
farnesyltransferase 4.5
neutral sphingomyelinase 4.5
AMPK 4.5
MMP-3 4.4
ceramide kinase 4.4
MMP 4.4
cathepsin V 4.4
sulfiredoxin 4.4
calcineurin 4.4
TACE 4.4
prenylated protein methyltransferase 4.4
ceramidase 4.4
matrix metalloproteinase 10 4.2
phospholipase C 4.2
TOR 4.2
inositol polyphosphate 4-phosphatase 4.2
phosphopantothenoylcysteine decarboxylase 4.2
small monomeric GTPase 4.2
AMP-activated kinase 4.2
CEP 4.1
3,4-dihydroxy-2-butanone-4-phosphate synthase 4.1
PI-PLC 4.1
more...
Compound
Fexaramine 8.4
Catenarin 8.4
C18H34O3 8.4
C20H21NO5 8.4
C15H20O 8.4
Linderane 8.4
C25H30N2O5 8.4
C13H9ClFNO2 8.4
C15H20O 8.4
C15H20O 8.4
C20H22O9 8.4
C20H22O9 8.4
C18H34O3 8.4
C18H34O3 8.4
C15H20O 8.4
Vernodalol 8.4
C18H34O3 8.4
C20H21NO5 8.4
C18H34O3 8.4
C20H21NO5 8.4
C15H20O 8.4
C18H34O3 8.4
C15H20O 8.4
C18H34O3 8.4
C15H20O 8.4
C20H21NO5 8.4
2-(2,5-dimethoxyphenyl)acetamide 8.4
C18H34O3 8.4
Tokoronin 8.4
C15H20O 8.4
C15H20O 8.4
C15H20O 8.4
S 46 8.4
C20H21NO5 8.4
C18H34O3 8.4
C15H20O 8.4
C20H21NO5 8.4
Longikaurin A 7.8
Bauerenol 7.4
C16H12O4 7.4
C15H20O 7.4
C18H16O7 7.4
Deoxygedunin 7.4
C16H20O5 7.4
C15H20O 7.4
C17H12 7.4
C17H12 7.4
C18H16O7 7.4
C14H16N2O4S 7.4
Telocinobufagin 7.4
4-Bromodiphenyl ether 7.4
C18H16O7 7.4
1-phenyl-1-nonen-3-one 7.4
C18H16O7 7.4
C17H12 7.4
Flurochloridone 7.4
C21H20N2O2 7.4
Isosamidin 7.4
4-Bromodiphenyl ether 7.4
C18H16O7 7.4
C18H16O7 7.4
C11H14O6 7.4
1-piperidinecarbothioamide 7.4
C18H16O7 7.4
Swertiajaponin 7.4
Gentisyl alcohol 7.4
C15H20O 7.4
C19H18O7 7.4
MEK 7.3
Tricetin 7.3
Hydrangenol 7.2
11H-indeno[1,2-b]quinoxalin-11-one 7.2
Deltonin 7.2
Farrerol 7.1
Tigogenin 7.1
Capillarisin 7.0
Eupafolin 6.9
Quinalizarin 6.9
LY 294002 6.8
2-(3,4,5-trimethoxyphenyl)-4H-chromen-4-one 6.8
more...