Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: EC:2.7.11.24 (
mitogen-activated protein kinase
)
95,810
document(s) hit in 31,850,051 MEDLINE articles (0.08 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
MAPK
0.310
ERK1
0.227
p38
0.182
JNK
0.171
extracellular signal-regulated kinase
0.126
MAP kinase
0.092
ERK
0.069
mitogen-activated protein
0.040
MEK
0.039
ERK2
0.029
p38 mitogen-activated protein kinase
0.029
MEK1
0.023
c-Jun
0.023
p42
0.017
p44
0.016
extracellular signal-regulated kinase 1
0.014
JNK1
0.013
PI3K
0.012
AKT
0.011
P38
0.007
phosphatidylinositol 3-kinase
0.006
AP-1
0.006
p38 MAP kinase
0.005
MAP
0.005
MKK4
0.005
p38MAPK
0.005
MEKK
0.005
caspase-3
0.004
BRAF
0.004
Raf-1
0.004
JNK2
0.004
protein kinase B
0.004
MKK3
0.003
p65
0.003
MKP-1
0.003
PKC
0.003
TNF
0.003
RAF
0.003
mTOR
0.003
MKK6
0.003
more...
Disease
cancer
0.002
tumor
0.002
tumorigenesis
0.001
tumor growth
0.001
breast cancer
0.001
melanoma
0.001
pertussis
0.001
MCF
0.001
tumor progression
0.000
hepatocellular carcinoma
0.000
carcinogenesis
0.000
Blocking
0.000
ischemia
0.000
neuroblastoma
0.000
Costello syndrome
0.000
colon cancer
0.000
atherosclerosis
0.000
glioma
0.000
lung cancer
0.000
Alzheimer's disease
0.000
cardiofaciocutaneous syndrome
0.000
colorectal cancer
0.000
prostate cancer
0.000
glioblastoma
0.000
carcinoma
0.000
leukemia
0.000
ATM
0.000
non-small cell lung cancer
0.000
GSH
0.000
pancreatic cancer
0.000
AGS
0.000
adenocarcinoma
0.000
ovarian cancer
0.000
obesity
0.000
metastatic melanoma
0.000
gastric cancer
0.000
diabetes
0.000
retinoblastoma
0.000
cerebral ischemia
0.000
Melanoma
0.000
more...
Symptom
starvation
0.000
pain
0.000
skin damage
0.000
Inflammatory pain
0.000
functional recovery
0.000
Neuropathic pain
0.000
hyperoxia
0.000
Scratch
0.000
impaired body balance
0.000
seizures
0.000
collapse
0.000
Thalamic pain
0.000
memory loss
0.000
acute stress
0.000
Incisional pain
0.000
cachexia
0.000
respiratory distress
0.000
diarrhea
0.000
Ear swelling
0.000
SYMPTOMS
0.000
hypothermia
0.000
analgesia
0.000
Mucosal hyperplasia
0.000
bone pain
0.000
Bladder distention
0.000
cardiovascular problem
0.000
despair
0.000
Organ failure
0.000
Central post-stroke pain
0.000
exhaustion
0.000
splenomegaly
0.000
Mechanical pain
0.000
orofacial pain
0.000
arthralgia
0.000
scaly skin
0.000
bladder pain
0.000
dry eye
0.000
impaired motor coordination
0.000
stomach cramps
0.000
erythema
0.000
more...
Drug
MAP
0.003
ROS
0.001
Angiotensin II
0.000
ICI
0.000
Sorafenib
0.000
Gefitinib
0.000
ETS
0.000
IL-2
0.000
Arsenic trioxide
0.000
p75
0.000
IFN-gamma
0.000
TAK
0.000
CSF
0.000
Epigallocatechin
0.000
NVP
0.000
uPA
0.000
Forskolin
0.000
Heme
0.000
Cetuximab
0.000
IL-11
0.000
Emodin
0.000
Rosiglitazone
0.000
Ciglitazone
0.000
Activin
0.000
lysine
0.000
Simvastatin
0.000
CCL
0.000
Erlotinib
0.000
Taxol
0.000
Herceptin
0.000
Emodin
0.000
Imatinib
0.000
Xaliproden
0.000
GEO
0.000
IFN-beta
0.000
Doramapimod
0.000
Fulvestrant
0.000
Myricetin
0.000
K-252a
0.000
Estrogens
0.000
more...
Enzyme
mitogen-activated protein kinase
1.000
MEK
0.065
ERK
0.030
protein kinase
0.010
MEKK1
0.007
protein kinase C
0.007
phosphatidylinositol 3-kinase
0.006
MAP
0.005
caspase-3
0.003
focal adhesion kinase
0.002
phosphoinositide 3-kinase
0.002
IKK
0.001
NADPH oxidase
0.001
PARP
0.001
NADPH oxidase
0.001
AMP-activated protein kinase
0.001
caspase-9
0.001
calcineurin
0.001
luciferase
0.001
GSK
0.001
phospholipase C
0.001
caspase-8
0.001
AMPK
0.001
AMPK
0.001
cdc2
0.000
CaMKII
0.000
protein phosphatase 2A
0.000
proteasome
0.000
NO synthase
0.000
superoxide dismutase
0.000
collagenase
0.000
MMP
0.000
inositol 3-kinase
0.000
MMP-3
0.000
phospholipase A2
0.000
catalase
0.000
PDK1
0.000
cathepsin K
0.000
PKG
0.000
sphingosine kinase
0.000
more...
Compound
MEK
0.030
MAP
0.004
tyrosine
0.004
TNF
0.003
oxygen
0.001
cAMP
0.001
threonine
0.001
serine
0.001
ATF
0.001
DNA
0.001
N-acetylcysteine
0.001
nitric oxide
0.001
calcium
0.001
Ang II
0.001
MTT
0.001
THP
0.001
THP
0.001
Wortmannin
0.001
PGE
0.000
MDA
0.000
LY 294002
0.000
glucose
0.000
PMA
0.000
acetate
0.000
HOG
0.000
Insulin
0.000
Dec
0.000
cysteine
0.000
Angiotensin II
0.000
Anisomycin
0.000
NH2
0.000
GTP
0.000
PMA
0.000
ATP
0.000
H2O2
0.000
AMP
0.000
GSH
0.000
GSH
0.000
dUTP
0.000
Curcumin
0.000
more...