Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:2.7.11.24 (mitogen-activated protein kinase)
95,810 document(s) hit in 31,850,051 MEDLINE articles (0.20 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
MAPK 30542
p38 22730
ERK1 22200
JNK 16370
ERK 13210
extracellular signal-regulated kinase 12069
Mol 11016
MAP kinase 8816
MEK 6851
mitogen-activated protein 6382
Sep 6225
cytokine 5952
PI3K 5145
c-Jun 5022
AKT 4957
caspase-3 4383
TNF 4243
p38 mitogen-activated protein kinase 3919
insulin 3869
IL-6 3678
tumor necrosis factor 3427
lipopolysaccharide 3245
ERK2 3123
MEK1 3063
p53 2993
Bcl-2 2944
tyrosine kinase 2885
mTOR 2647
phosphatidylinositol 3-kinase 2594
phosphatase 2497
AP-1 2488
collagen 2185
p42 2166
p65 2093
p44 2091
epidermal growth factor receptor 2080
extracellular signal-regulated kinase 1 2056
PKC 1996
BRAF 1952
inducible nitric oxide synthase 1929
MAP 1906
epidermal growth factor 1899
LPS 1798
IL-8 1763
JNK1 1699
p21 1653
TLR4 1565
protein kinase B 1539
threonine 1533
STAT3 1527
ATP 1495
ROS 1484
cyclooxygenase-2 1423
endoplasmic reticulum 1390
EGFR 1365
vascular endothelial growth factor 1347
cyclin D1 1340
STAT 1334
Raf-1 1318
matrix metalloproteinase 1297
chemokine 1287
TNF-alpha 1286
EGF 1211
interleukin-6 1173
p38 MAP kinase 1147
cytochrome c 1138
phosphoinositide 3-kinase 1121
Rho 1088
COX-2 1080
receptor tyrosine kinase 1034
c-fos 1033
CREB 1027
IL-10 1018
P38 1017
PARP 997
angiotensin II 996
p38MAPK 994
PKA 977
MMP-9 972
fibronectin 966
estrogen receptor 938
IFN 912
catenin 904
caspase-9 897
VEGF 865
EGF receptor 846
Ang II 842
proteasome 830
nerve growth factor 819
superoxide dismutase 812
caspase-8 804
focal adhesion kinase 801
platelet-derived growth factor 800
brain-derived neurotrophic factor 792
nitric oxide synthase 792
PI3 788
AMP 785
IRS-1 780
ubiquitin 766
catalase 766
GSH 760
calmodulin 754
RAF 748
TLR2 742
interferon 738
THP 734
GTP 718
E-cadherin 717
IL-1 711
ras 704
MEKK 701
heme oxygenase-1 686
KRAS 686
MMP-2 682
MKK4 680
insulin receptor 679
CD4 667
RhoA 620
p27 618
osteogenic 614
Nrf2 608
tumor necrosis factor alpha 607
histone 607
GTPase 600
Fas 585
cyclin 584
c-Src 580
JNK2 576
G protein-coupled receptor 572
GSK 571
AMPK 569
erythroid 559
PKB 549
IL-4 549
alkaline phosphatase 548
FAK 543
PTEN 538
MCP-1 532
TGF-beta 532
insulin-like growth factor 529
PDGF 526
cyclooxygenase 525
RANKL 523
proliferating cell nuclear antigen 523
AMP-activated protein kinase 521
annexin V 519
adaptor protein 519
IL-2 519
leptin 515
thrombin 501
serine/threonine kinase 499
JAK2 493
MyD88 487
FGF 487
IKK 482
hepatocyte growth factor 480
Smad2 479
HER2 468
PLC 464
calcineurin 463
ATPase 457
MKK3 449
Cytokine 447
peroxisome proliferator-activated receptor 441
STAT1 440
protein phosphatase 435
gut 433
CA1 430
IFN-gamma 426
adenylyl cyclase 425
glycoprotein 421
c-Myc 420
phosphorylating 416
ICAM-1 415
axonal 413
PP2 413
arrestin 412
IL-17 402
endothelin-1 401
SOD 401
extracellular signal regulated kinase 401
MEKK1 401
STAT5 399
lactate dehydrogenase 397
MKP-1 397
IGF-I 394
LC3 391
neurotrophin 388
ATF 388
signal transducer and activator of transcription 3 386
Tumor necrosis factor 385
IkappaBalpha 385
ASK1 384
interacting protein 382
HO-1 376
SHP-2 376
CXCR4 375
TCR 375
protein tyrosine phosphatase 374
VEGFR2 373
NRAS 372
proto-oncogene 369
CHOP 368
CD40 366
vimentin 366
myeloperoxidase 364
peroxisome proliferator-activated receptor gamma 362
mast cell 361
ribosomal S6 kinase 361
Smad3 361
amyloid precursor protein 358
CCL2 357
lymphoid 355
CD8 355
metalloproteinase 354
MKK6 353
ERK5 351
H-ras 350
SMA 349
vascular cell adhesion molecule-1 348
tyrosine phosphatase 347
NS5 347
histone deacetylase 347
MMP9 346
Sp1 345
cyclin-dependent kinase 345
phospholipase 344
IGF-1 342
Janus kinase 341
myelin basic protein 339
cAMP response element-binding protein 334
p70 334
protein tyrosine kinase 334
poly(ADP-ribose) polymerase 331
p50 330
heat shock protein 329
MMP-1 328
TAK1 325
cyclin E 325
glial fibrillary acidic protein 323
beta-catenin 322
TNF receptor 322
p85 320
TRAF6 319
MKK7 318
NMDA receptor 318
ADP 317
osteosarcoma 315
fused 311
Mcl-1 310
membrane protein 309
MEK2 307
glutathione peroxidase 307
S6K1 306
paxillin 305
CDK4 304
CD44 303
c-myc 302
small GTPase 302
histone H3 302
transforming growth factor-beta 301
monocyte chemoattractant protein-1 298
polypeptide 298
osteocalcin 298
IgE 296
urokinase-type plasminogen activator 295
smooth muscle actin 295
adhesion molecule 294
MAPK/ERK kinase 294
CaMKII 291
apoptosis signal-regulating kinase 1 290
adenylate cyclase 290
p90 290
renin 289
adiponectin 288
kit 285
CXCL12 283
T cell receptor 283
erbB-2 282
PI3-kinase 281
caveolin-1 280
membrane-bound 278
proteasome inhibitor 278
G-protein-coupled receptor 278
HEK 277
RANTES 277
phosphoprotein 275
CD14 273
androgen receptor 273
p62 273
PP1 271
N-cadherin 268
MAP2K1 265
macrophage colony-stimulating factor 265
cyclin B1 262
type I collagen 262
tyrosine hydroxylase 260
MMP 260
survivin 260
CCK 259
eNOS 257
Leptin 255
endothelial nitric oxide synthase 252
Pseudomonas 252
osteopontin 251
bradykinin 251
UTR 249
cAMP-dependent protein kinase 249
interferon-gamma 245
Met 244
glutathione S-transferase 244
NAC 243
glucocorticoid receptor 241
CDK2 238
mucin 238
GST 237
EBP 234
CD86 234
PC-3 234
A431 233
more...
Disease
cancer 14230
tumor 10060
breast cancer 3003
tumorigenesis 2221
tumor growth 2193
melanoma 1960
diabetes 1719
ischemia 1638
hepatocellular carcinoma 1601
carcinoma 1595
Alzheimer's disease 1485
carcinogenesis 1484
tumor progression 1355
atherosclerosis 1330
obesity 1243
leukemia 1224
lung cancer 1217
MCF 1177
prostate cancer 1029
pertussis 994
colorectal cancer 989
adenocarcinoma 976
hypertension 921
neuroblastoma 870
glioma 830
colon cancer 813
GSH 760
Parkinson's disease 725
asthma 675
metastases 668
type 2 diabetes 647
squamous cell carcinoma 636
rheumatoid arthritis 632
gastric cancer 628
ovarian cancer 625
stroke 618
non-small cell lung cancer 596
depression 577
glioblastoma 554
Blocking 545
pancreatic cancer 544
heart failure 525
sepsis 521
sepsis 506
acute myeloid leukemia 492
osteoporosis 469
ATM 454
hyperglycemia 452
HIV 446
multiple myeloma 439
arthritis 430
lymphoma 428
cerebral ischemia 419
cardiovascular disease 404
osteoarthritis 376
myocardial infarction 373
infectious diseases 370
B-cell lymphoma 366
virus infection 364
osteosarcoma 348
retinoblastoma 339
liver cancer 335
colitis 325
lung carcinoma 312
cold 311
pheochromocytoma 308
cognitive impairment 296
chronic myeloid leukemia 293
Mycobacterium 293
diabetic nephropathy 292
myocardial ischemia 282
Melanoma 281
plaque 276
chronic obstructive pulmonary disease 269
metastatic melanoma 264
liver cancer 262
bladder cancer 252
tumor angiogenesis 249
skin cancer 246
inflammatory bowel disease 243
immunodeficiency 241
sarcoma 240
tuberculosis 240
multiple sclerosis 239
Infection 237
thyroid cancer 235
cervical cancer 232
liver fibrosis 227
bacterial infection 227
metabolic syndrome 223
fatty liver 211
renal disease 210
psoriasis 210
dementia 209
MIP 200
renal cell carcinoma 195
epithelial ovarian cancer 191
astrocytoma 187
Epstein 186
NAME 183
glioblastoma multiforme 182
aggressiveness 181
periodontitis 180
SDS 180
Hepatocellular carcinoma 177
Leukemia 177
AGS 176
autoimmune disease 171
epilepsy 167
cardiomyopathy 166
fibrosarcoma 162
brain tumor 162
acute promyelocytic leukemia 161
schizophrenia 160
HGF 160
NOD 159
pulmonary fibrosis 157
vascular disease 156
systemic lupus erythematosus 153
primary tumor 152
SCID 151
hyperinsulinemia 148
hepatitis B 147
proteinuria 147
influenza 147
cirrhosis 146
endometrial cancer 146
atopic dermatitis 143
uterus 142
chronic pain 139
addiction 136
diabetic retinopathy 133
APC 132
dermatitis 132
papillary thyroid cancer 131
mammary tumor 129
myeloid leukemia 128
DDP 127
liver disease 126
Adhesion 124
chronic lymphocytic leukemia 124
neoplastic transformation 123
memory impairment 123
neurofibromatosis type 1 123
acute lymphoblastic leukemia 121
amyotrophic lateral sclerosis 121
pulmonary hypertension 121
heart disease 121
encephalomyelitis 121
hepatitis C 120
tumor initiation 119
Crohn's disease 117
type 1 diabetes 115
AIDS 113
pneumonia 112
EMT 111
oral cancer 111
ABL 111
hepatitis 110
dysplasia 109
anthrax 108
Huntington's disease 106
ulcerative colitis 104
cholera 104
glucose intolerance 102
coronary artery disease 102
endometriosis 101
solid tumor 99
chronic lymphocytic leukemia 99
Kaposi's sarcoma 99
adenoma 97
lung disease 95
polycystic kidney 95
hyperlipidemia 94
brain edema 94
leukemogenesis 93
autism 93
glomerulosclerosis 93
cystic fibrosis 93
Osteosarcoma 92
Osteosarcoma 92
renal failure 91
worms 91
tuberous sclerosis 90
preeclampsia 89
anemia 89
Costello syndrome 89
malnutrition 89
pulmonary edema 89
acute myocardial infarction 89
cutaneous melanoma 88
skin disease 88
neuropathy 87
mole 87
herpes simplex 86
esophageal cancer 86
dyslipidemia 85
Steroids 85
malaria 85
Glioblastoma 85
MTS 85
infertility 84
Evans 83
ventricular hypertrophy 82
acute pancreatitis 82
Hodgkin's disease 81
insulinoma 81
periodontal disease 80
FAS 80
anaphylaxis 79
mental retardation 79
cornea 79
choriocarcinoma 79
idiopathic pulmonary fibrosis 79
lupus 79
vaccinia 78
mental retardation 78
esophageal cancer 78
cytomegalovirus 77
pancreatitis 77
glomerulonephritis 77
Adenovirus 76
myeloproliferative disorders 76
hematologic malignancies 76
Pineal 73
hypertrophic cardiomyopathy 73
dilated cardiomyopathy 73
muscular atrophy 73
Langerhans cell histiocytosis 72
Yersinia 71
genetic disorder 71
metastatic breast cancer 71
lupus 70
small cell lung cancer 70
erythroleukemia 69
macular degeneration 69
subarachnoid hemorrhage 69
rhabdomyosarcoma 65
medulloblastoma 65
hypercholesterolemia 65
TAM 64
diabetic cardiomyopathy 64
renal ischemia 64
mastitis 64
aggression 63
HCC 63
myelodysplastic syndrome 63
glaucoma 63
mesothelioma 62
blindness 62
skin tumor 62
retinopathy 61
chronic hepatitis 61
bone disease 61
drug addiction 61
Cryptococcus neoformans 61
thymoma 60
pruritus 60
neurofibromatosis 60
coronary heart disease 59
Burkitt's lymphoma 59
chondrosarcoma 59
CEP 58
polycystic ovary syndrome 58
bipolar disorder 57
chronic renal failure 57
renal cancer 56
Neuroblastoma 56
Neuroblastoma 56
anaplastic thyroid cancer 55
disc degeneration 55
peripheral neuropathy 54
myocarditis 54
developmental delay 53
major depressive disorder 53
CCL 53
Placenta 52
Brown 52
cerebral infarction 52
HSP 52
ARF 51
lung metastases 51
WT1 50
fungal infection 50
hyperhomocysteinemia 50
abortion 50
congestive heart failure 49
FBS 49
arthropathy 48
medullary thyroid carcinoma 48
PTP 48
PHA 48
meningitis 48
parkinsonism 48
metabolic disorder 47
Recruitment 47
head and neck cancer 47
Tumour necrosis 47
Nonalcoholic fatty liver 46
emphysema 46
endotoxic shock 46
INS 46
Thyroid cancer 46
SARS 46
Hippel 46
mole 45
JIP 45
encephalitis 45
DSS 44
Ewing's sarcoma 44
COPD 43
cholestasis 43
wasting 43
Nasopharyngeal carcinoma 43
Frey 43
LTD 42
Chlamydia 42
stromal tumors 42
DSS 41
dyskinesia 41
more...
Symptom
pain 923
starvation 395
seizures 202
functional recovery 145
diarrhea 132
collapse 115
anesthesia 79
respiratory distress 78
analgesia 75
hyperoxia 73
hypothermia 62
fatigue 62
skin damage 62
headache 45
Neuropathic pain 42
cachexia 42
exhaustion 41
acute stress 39
memory loss 35
weakness 34
splenomegaly 34
ataxia 31
erythema 31
cough 29
overweight 28
arthralgia 25
thinning 24
nausea 23
bone pain 23
vomiting 21
low back pain 21
angina 18
anorexia 18
Scratch 16
dyspnea 15
pelvic pain 14
dry eye 14
despair 14
hypotonia 14
tremor 13
HSA 13
hypercapnia 12
abdominal pain 12
constipation 11
Inflammatory pain 11
back pain 11
hepatomegaly 10
myalgia 10
cancer pain 9
acidity 9
orofacial pain 9
acute pain 9
hepatosplenomegaly 9
insomnia 7
spasm 7
dry skin 7
flushing 6
sore throat 6
bradykinesia 6
neurological disability 6
fasciculation 6
incoordination 6
menopausal symptoms 6
skin irritation 6
stigma 5
discomfort 5
discomfort 5
distraction 5
twitching 5
chest pain 5
agitation 5
decreased appetite 5
lethargy 5
dizziness 5
bladder pain 5
numbness 5
muscle cramps 5
neuralgia 4
microbial colonization 4
wheezing 4
Depressive symptoms 4
cerebellar ataxia 4
dystonia 4
Anoxia 4
scaly skin 3
facial pain 3
Wind 3
impaired motor coordination 3
polyuria 3
vertigo 3
myoclonus 3
sciatica 3
masculinization 3
nasal congestion 3
muscle stiffness 3
Ear swelling 3
polydipsia 3
spasticity 3
dental pain 3
nausea and vomiting 3
tinnitus 3
rundown 2
paresthesia 2
asthenia 2
Halo 2
Mills 2
Noise-induced hearing loss 2
Macula 2
hoarseness 2
hemiplegia 2
hunger 2
ACHE 2
Organ failure 2
chills 2
ENT 2
ataxic gait 2
paraparesis 2
chorea 2
Decreased activity 2
rhinorrhea 2
sleepiness 2
swollen joints 2
dysarthria 2
regurgitation 2
paresis 2
Ill 2
loss of balance 2
bitter taste 2
female puberty 2
bedwetting 1
impaired body balance 1
abnormal gait 1
bradypnea 1
disturbed balance 1
tonic-clonic seizure 1
Hudson 1
stomach cramps 1
halitosis 1
periorbital edema 1
SYMPTOMS 1
GI irritation 1
heartburn 1
Motor dysfunction 1
Behavioral symptoms 1
hemoptysis 1
night sweats 1
male subfertility 1
Incisional pain 1
prostration 1
livedo 1
hot flashes 1
Bladder distention 1
POA 1
delayed language development 1
Thalamic pain 1
forgetfulness 1
eye pain 1
colic 1
catatonia 1
Catch 1
Visceral pain 1
muscle rigidity 1
abdominal cramps 1
Mechanical pain 1
Central post-stroke pain 1
catarrh 1
neck pain 1
sneezing 1
CSR 1
Mucosal hyperplasia 1
photophobia 1
stomach pain 1
chronic back pain 1
exertional dyspnea 1
chronic cough 1
chronic constipation 1
ophthalmoplegia 1
dysesthesia 1
skin irritant 1
pallor 1
motor symptom 1
syncope 1
cardiovascular problem 1
dysuria 1
otalgia 1
anosmia 1
hopelessness 1
emaciation 1
Fluctuation 1
Drug
MAP 1988
ROS 1484
Dermatol 541
IL-2 519
IFN-gamma 421
lysine 369
CSF 368
Angiotensin II 344
ICI 251
Cardiovasc 212
p75 164
ETS 161
Sorafenib 131
Monit 128
vitamin E 124
ascorbate 121
caffeine 119
Gefitinib 114
Ethanol 112
Arsenic trioxide 99
EE2 94
Heme 92
Forskolin 89
Gel 88
uPA 86
Taxol 83
IFN-beta 73
Imatinib 71
TAK 69
Herceptin 69
Retinoic acid 64
Activin 63
ETA 63
NVP 61
TAT 61
Simvastatin 61
NADH 60
Estrogens 59
G-CSF 58
Glutathione 58
Indomethacin 56
Asthma 53
Nitric Oxide 53
GEO 53
IL-11 53
CCL 53
PTH 51
Glucagon 51
Histamine 50
Cetuximab 50
Gelatin 50
Nephron 50
Ouabain 49
ADR 49
CTX 49
Rosiglitazone 44
Growth hormone 44
PTC 44
Growth hormone 44
Asn 43
Gleevec 43
Glycyrrhiza 41
Bortezomib 41
Epigallocatechin 41
Erlotinib 40
ABC 40
Lovastatin 38
MRC 37
CAM 36
Leaf 34
Emodin 34
Emodin 34
Parkin 32
Propofol 32
Parkin 32
PCP 32
Portal 31
Dasatinib 30
IL-1ra 29
CTX 28
Albumin 28
Ginseng 28
CTX 27
Bifidobacterium 27
Mutagen 27
CoCl2 26
CoCl2 26
Adriamycin 24
Docetaxel 24
lactose 24
Fulvestrant 24
K-252a 23
Vitamin E 23
EPA 23
PFT 22
ZnO 22
Myricetin 22
GHRP 22
Rutin 21
TiO2 21
nitroglycerin 20
DEX 19
Alanine 19
Oxaliplatin 19
DNase I 19
RAL 18
Pravastatin 18
TEL 17
-deoxyadenosine 17
Troglitazone 17
Silica 17
KGF 16
Etoposide 16
ALA 16
Bevacizumab 16
Glycerol 16
Rituximab 16
Tarceva 16
ADM 16
Fluorescein 16
GRF 15
Liraglutide 15
Photofrin 15
citric acid 15
G418 14
Kenyan 14
DHT 14
Doxycycline 14
TTC 14
CED 14
RFP 14
DHT 14
2-Methoxyestradiol 13
Capsicum 13
Olmesartan 13
Paraffin 13
ROC 13
PDL 13
3-Methyladenine 13
Ciglitazone 13
Triclosan 13
Everolimus 12
Zoledronic acid 12
BH4 12
niacin 12
Ginger 12
Rosuvastatin 12
NBT 12
FAD 12
ENT 11
Vandetanib 11
HCH 11
Fructose 11
Amiloride 11
Raloxifene 11
DMAP 11
Cilostazol 11
Salicylate 10
Luteinizing 10
AMC 10
Alliance 10
Sodium nitroprusside 10
Flavopiridol 10
Vitamin A 10
Nexavar 10
Kainic acid 10
Itraconazole 10
Fluorescein 10
PCB 9
CaCl2 9
pyridoxal phosphate 9
Tocopherol 9
MDS 9
9-THC 9
CaCl2 9
CaCl2 9
TAC 9
Fraction 9
R1881 9
Adenosine triphosphate 9
BLM 9
Doyle 8
Vitamin K 8
Aliskiren 8
Sesamol 8
Vorinostat 8
Tranilast 8
Mycophenolic acid 8
Spectrum 8
Casodex 8
Rolipram 8
ID2 8
VCR 8
AraC 8
Artesunate 7
Zoledronic acid 7
Verteporfin 7
Red ginseng 7
Ezetimibe 7
Limonene 7
Nephron 7
Amiloride 7
Ulinastatin 7
Imiquimod 7
Orphan 7
Acacia 7
Tipifarnib 7
Donepezil 7
Ipilimumab 7
Rasagiline 7
TMS 6
Tannic acid 6
Dihydro 6
PFA 6
Bromelain 6
Dial 6
Scopolamine 6
Theophylline 6
ZnCl2 6
Biopolymers 6
Pirfenidone 6
Fentanyl 6
CIA 6
ZnCl2 6
Anakinra 6
Captopril 6
Dihydrotestosterone 6
CPT-11 6
Panitumumab 6
Phosphatidylserine 6
Pemetrexed 6
Areca 5
Olomoucine 5
NOV 5
Romidepsin 5
Bumetanide 5
Azithromycin 5
PNT 5
Glide 5
Exenatide 5
Valsartan 5
Benfotiamine 5
Pertuzumab 5
VCR 5
Norplant 5
AIC 5
Urokinase 5
PDGF B-chain 5
SiO2 5
MTC 5
Fragment 5
Isoniazid 5
Iloprost 5
BoNT/A 5
Tocilizumab 5
Tianeptine 5
NAG 5
Radicicol 5
Apomorphine 5
BTC 5
Tao 5
MDM 5
Taxotere 5
FeCl3 5
Sunitinib malate 4
Tolfenamic acid 4
Fluticasone propionate 4
Atropine 4
Cetrorelix 4
Iodixanol 4
Glutamic acid 4
Trapidil 4
Roflumilast 4
Palmitoyl 4
Clopidogrel 4
Secretin 4
Safflower 4
ACT 4
AZT 4
DEL 4
Lenalidomide 4
Bupivacaine 4
Vinorelbine 4
AZT 4
Caspofungin 4
Roflumilast 4
Ranitidine 4
Amlexanox 4
Vitamin K2 4
Prednisolone 4
Xanthium 4
CTC 4
Marimastat 4
Crystal Violet 4
Tykerb 4
Aloe 4
CTC 4
Isotretinoin 4
Abamectin 4
Scutellaria root 4
Bosutinib 4
Ringer's solution 4
Aminoguanidine 4
Micafungin 4
Hypaque 3
Propidium 3
Domin 3
Hyaluronidase 3
Artemether 3
Ketoconazole 3
Mevastatin 3
Colistin 3
Allergen 3
Epalrestat 3
Febuxostat 3
CDP 3
Tolvaptan 3
THF 3
Bosentan 3
Cinacalcet 3
more...
Enzyme
mitogen-activated protein kinase 95810
ERK 16661
MEK 10639
protein kinase 8941
protein kinase C 5579
caspase-3 3450
focal adhesion kinase 3173
phosphatidylinositol 3-kinase 2598
MAP 1909
luciferase 1613
MEKK1 1152
phosphoinositide 3-kinase 1121
PARP 1114
superoxide dismutase 1114
calcineurin 1083
NADPH oxidase 1072
AMP-activated protein kinase 1050
phospholipase C 1048
NADPH oxidase 948
catalase 894
proteasome 848
AMPK 817
IKK 725
caspase-9 721
GSK 642
caspase-8 613
cdc2 607
NO synthase 597
collagenase 571
AMPK 570
alkaline phosphatase 549
ATPase 502
thrombin 494
glutathione S-transferase 474
peroxidase 464
phospholipase A2 455
lactate dehydrogenase 412
CaMKII 385
urokinase-type plasminogen activator 342
alanine aminotransferase 339
adenylate cyclase 315
glutathione peroxidase 314
renin 289
protein phosphatase 2A 281
MMP 270
aspartate aminotransferase 268
tyrosine hydroxylase 250
caspase-1 232
MMP-3 224
reverse transcriptase 224
phosphodiesterase 223
heme oxygenase 205
MIP 200
RNA polymerase 191
tyrosinase 190
NOS 190
APC 188
PKG 181
phospholipase D 176
PDK1 175
ACS 175
guanylate cyclase 165
trypsin 163
cathepsin K 157
P-glycoprotein 154
NQO1 129
myosin light chain kinase 127
acetylcholinesterase 117
matrix metalloproteinase 9 110
GRK5 106
complex I 103
AST 103
DCF 99
farnesyltransferase 99
lipoxygenase 98
sphingosine kinase 98
creatine kinase 98
MPP 97
xanthine oxidase 97
glutathione reductase 92
farnesyltransferase 90
tissue plasminogen activator 88
histidine kinase 86
kinesin 84
TOR 83
GRK2 83
topoisomerase 82
acetyl-CoA carboxylase 80
caspase-7 75
caspase-7 75
matrix metalloproteinase 2 75
topoisomerase 74
ACE 74
PTPase 74
RNase 70
ornithine decarboxylase 70
hexosaminidase 69
lipase 68
RNase 66
beta-galactosidase 65
elastase 64
hormone-sensitive lipase 64
cathepsin B 62
TAT 61
inositol 3-kinase 60
CPT 59
CEP 59
histone acetyltransferase 58
gamma-glutamylcysteine synthetase 58
CEP 58
plasmin 57
TdT 56
CD10 55
arginase 55
neutrophil elastase 54
acid phosphatase 54
peroxiredoxin 53
aldose reductase 52
phosphoenolpyruvate carboxykinase 51
CPT 51
CPT 50
TACE 50
succinate dehydrogenase 49
thioredoxin reductase 49
DNA methyltransferase 47
choline acetyltransferase 47
polo-like kinase 1 46
transcriptase 46
interstitial collagenase 46
lysozyme 45
lipoprotein lipase 44
neutral sphingomyelinase 44
neuraminidase 42
glyceraldehyde-3-phosphate dehydrogenase 42
furin 42
tryptase 41
aldehyde dehydrogenase 40
triphosphatase 39
cathepsin D 39
HSD 39
chloramphenicol acetyltransferase 39
phosphoenolpyruvate carboxykinase 38
thromboplastin 38
phosphoenolpyruvate carboxykinase 38
caspase-2 37
kallikrein 37
prostate-specific antigen 37
caspase-2 36
caspase-4 36
transglutaminase 35
aldehyde dehydrogenase 34
PDE 34
granzyme B 34
aldehyde dehydrogenase 33
aldehyde dehydrogenase 33
aldehyde dehydrogenase 33
monoamine oxidase 33
caspase-4 33
PCP 32
15-lipoxygenase 32
phosphatidylinositol-4,5-bisphosphate 3-kinase 32
lysyl oxidase 31
PI-PLC 30
glutamine synthetase 29
12-lipoxygenase 29
prostaglandin synthetase 28
cellulose synthase 28
CYP7A1 28
hyaluronidase 28
sialidase 27
cholinesterase 27
p100 27
chitinase 26
diacylglycerol kinase 26
glyceraldehyde-3-phosphate dehydrogenase 26
ECH 26
CLK1 26
factor C 26
eEF2 kinase 26
m-calpain 25
AMP-activated kinase 25
hexokinase 25
DNA polymerase 25
glycerol-3-phosphate dehydrogenase 24
glycerol-3-phosphate dehydrogenase 24
CD13 24
inositol phosphatase 24
hyaluronidase 24
ribonucleotide reductase 24
adenosine deaminase 23
glucokinase 23
adenosine deaminase 23
enolase 23
apyrase 23
glucose oxidase 23
firefly luciferase 23
ribonucleotide reductase 23
pyruvate dehydrogenase 22
gamma-glutamyl transpeptidase 22
mu-calpain 21
endonuclease 21
ceramidase 21
ATP synthase 21
cathepsin L 21
thymidine kinase 20
caspase-6 20
phosphatidylinositol 4-kinase 20
glyceraldehyde-3-phosphate dehydrogenase 20
histidine decarboxylase 20
glucosylceramide synthase 20
angiotensin-converting enzyme 2 20
caspase-6 20
prolidase 19
CAD 19
MDR 19
15-hydroxyprostaglandin dehydrogenase 19
glyceraldehyde-3-phosphate dehydrogenase 19
glyceraldehyde-3-phosphate dehydrogenase 19
citrate synthase 19
CAD 19
alcohol dehydrogenase 19
prolyl hydroxylase 19
phosphorylase 19
CAD 19
GAS 19
adenosine kinase 18
BAL 18
glucose-6-phosphatase 18
pyruvate dehydrogenase 18
tissue kallikrein 18
3-hydroxy-3-methylglutaryl coenzyme A reductase 18
soluble epoxide hydrolase 18
demethylase 18
pyruvate dehydrogenase 18
glucose-6-phosphate dehydrogenase 17
SPT 17
sialyltransferase 17
sialyltransferase 17
HK2 17
sialyltransferase 17
pyruvate kinase 17
thyroid peroxidase 17
cytochrome oxidase 17
chymase 17
ribonuclease 17
ribonuclease 17
CYP3A4 16
PAL 16
carbonic anhydrase 16
papain 16
ricin 16
indoleamine 2,3-dioxygenase 16
PRE 15
PAH 15
chymotrypsin 15
O-GlcNAc transferase 15
endothelin-converting enzyme 15
ascorbate peroxidase 14
beta-secretase 14
GalT 14
tryptophan hydroxylase 14
HCS 14
phosphofructokinase 14
cholesterol acyltransferase 14
peptidyl-prolyl cis-trans isomerase 14
proteinase K 13
sulfatase 13
laccase 13
diaphorase 13
LPL 13
TSP-1 13
TSA 13
3beta-hydroxysteroid dehydrogenase 12
proprotein convertase 12
Thy1 12
FPS 12
PAL 12
insulin-degrading enzyme 12
thymidylate synthase 12
3-hydroxy-3-methylglutaryl-CoA reductase 12
nicotinamide phosphoribosyltransferase 12
DNA ligase 12
DNA ligase 12
NSY 12
callose synthase 11
MDP 11
biliverdin reductase 11
isopeptidase 11
glutathione synthetase 11
protein farnesyltransferase 11
N-acetyltransferase 11
Omi/HtrA2 11
heparinase 11
aconitase 11
SPC 11
p80 11
CPS 11
ALDH 11
cathepsin G 11
dipeptidyl peptidase IV 10
ADP-ribosyltransferase 10
chitin synthase 10
ubiquitin-protein ligase 10
chaperonin 10
ADP-ribosyltransferase 10
D-dopachrome tautomerase 10
dihydrofolate reductase 10
glutaminase 10
subtilisin 9
sucrase-isomaltase 9
PAM 9
nitrate reductase 9
cGMP phosphodiesterase 9
ceruloplasmin 9
cathepsin S 9
myosin ATPase 9
matriptase 9
Protein 2 9
sucrase 9
cellulase 9
more...
Compound
DNA 7460
Dec 6800
oxygen 6780
MEK 6032
tyrosine 5762
calcium 4543
TNF 4243
glucose 3076
serine 2693
cAMP 2673
nitric oxide 2498
threonine 2301
MAP 1912
acetate 1741
Clin 1531
ATP 1499
sodium 1325
MTT 1324
water 1271
cysteine 1242
phosphate 1198
hydrogen 1106
MDA 1053
glutamate 970
NH2 911
N-acetylcysteine 838
AMP 822
Insulin 818
GSH 795
GSH 795
THP 736
THP 735
GTP 720
H2O2 718
alanine 683
arginine 654
PGE 645
Ang II 639
ethanol 633
methionine 591
leucine 576
lysine 550
sulfate 528
PMA 465
PMA 451
retinoic acid 451
Phe 435
nitrogen 430
Angiotensin II 419
salt 416
cGMP 413
glycerol 399
bromide 397
zinc 396
ATF 388
galactose 375
Cardiol 372
ADP 363
proline 355
iodine 352
PGE2 350
NMDA 350
iron 350
potassium 347
COS 340
Asp 332
dUTP 331
ADP 320
ADP 317
Curcumin 294
5-HT 274
urea 263
cadmium 261
ICI 252
Panam 244
Wortmannin 237
NAD 231
Resveratrol 230
Tyrosine 219
ADP-ribose 210
aldosterone 202
DDP 202
Estrogen 196
Gly 194
His 193
pyrimidine 193
nicotinamide 192
Estrogen 192
boron 191
pyrimidine 188
ASA 188
creatinine 187
salicylic acid 185
SDS 183
vitamin D 182
TPA 179
BCR 179
TPA 179
palmitic acid 177
NADPH 176
GDP 175
ACS 175
NADPH 175
pyrrolidine 175
ACS 175
Neuronal 166
Melatonin 166
NAD 166
Phosphatidylinositol 164
Rapamycin 163
APAP 158
glutamine 155
Quercetin 153
diacetate 153
pyrrolidine 152
AMPA 149
Thrombin 147
copper 147
H2S 145
CO2 142
Genistein 141
CAT 140
CAT 139
Cbl 139
CAT 139
Estradiol 136
GABA 135
ADR 135
Serine 134
GABA 131
Collagen 131
PEG 129
ALP 129
1H-imidazole 129
MPTP 128
aldehyde 128
DMSO 127
manganese 127
selenium 125
ethyl acetate 123
ABL 120
caffeine 120
HOG 116
prostacyclin 116
UTP 114
tryptophan 112
Glutamate 110
Adriamycin 110
aldehyde 109
Adenosine 108
PLA 107
glutamic acid 107
acetic acid 104
Cer 104
noradrenaline 104
aspartic acid 103
1H-imidazole 102
pyridine 102
FK506 100
palmitic acid 99
LY 294002 97
kaempferol 97
MPP 97
MPP 97
Vimentin 97
titanium 96
Dexamethasone 96
methanol 95
homocysteine 94
Heme 93
cobalt 92
GSSG 91
TEM 91
GAP 90
Thyroid 89
Forskolin 89
Progesterone 88
PEG 86
Berberine 85
Metformin 85
Metformin 85
aspartic acid 85
Cereb 84
MTS 84
ammonium 84
Ile 82
ACTH 81
silver 81
GMP 81
adenylate 81
1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine 80
aspartic acid 79
aspartic acid 79
STZ 79
4-chlorophenyl 77
Luteolin 77
4-chlorophenyl 77
TNM 76
tryptophan 76
Pac 76
Retinal 75
COX 75
uridine 75
Sphingosine 75
GF 109203X 74
tryptophan 73
Nicotine 73
tryptophan 73
Tamoxifen 73
anthracene 72
Tamoxifen 72
L-DOPA 71
Cholesterol 71
phosphoserine 71
hyaluronic acid 70
Isoproterenol 70
TOF 70
chalcone 70
Bisphenol A 69
pyrene 69
SCC 69
Dopamine 69
H2S 69
Bisphenol A 69
Arsenic 68
nitrate 68
isoquinoline 68
valine 67
superoxide radical 67
Morphine 66
naphthoquinone 65
naphthoquinone 65
naphthoquinone 65
naphthoquinone 65
Hoechst 33342 65
naphthoquinone 65
naphthoquinone 65
8-OHdG 65
naphthoquinone 65
ETA 65
Tanshinone 63
Histone 63
Phorbol 63
gallic acid 63
phenol 63
DBA 62
adenosylmethionine 62
fluorine 62
TSH 61
NADH 60
Anisomycin 60
DPI 59
hydroxide 58
Arachidonic acid 57
Cycloheximide 57
Silymarin 57
ACh 57
Paclitaxel 57
2-nonenal 57
GlcNAc 56
5-FU 56
MIA 55
Baicalein 55
tin 54
Mg2+ 54
AICAR 54
Vitamin D 54
DHA 54
Sphingosine 1-phosphate 54
acridine 54
tert-butyl hydroperoxide 54
Staurosporine 53
Staurosporine 53
Apigenin 52
CoA 52
Emodin 52
Sulforaphane 52
gamma-aminobutyric acid 52
nickel 52
butyric acid 52
ABA 52
HCl 51
Guo 51
Hearts 51
PAR 51
Glucagon 51
TACE 51
Bradykinin 50
chromium 50
Epigallocatechin 50
Carbachol 50
CPT 50
Histamine 50
CPT 50
Epigallocatechin gallate 49
PGJ2 49
Ouabain 49
CTX 49
Heparin 49
Okadaic acid 48
TTC 48
Cyclosporine 48
mercury 48
Arsenite 48
Glycogen synthase 47
GM1 47
Hematoxylin 47
BNP 46
CCl4 46
AICAR 46
Cyt 45
Hearts 45
bis(2-chloroethyl) 45
Phorbol 12-myristate 13-acetate 44
DEHP 44
ammonia 44
LTD 44
DPG 44
Leucine 43
VP-16 43
more...