Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: EC:2.7.11.24 (
mitogen-activated protein kinase
)
95,810
document(s) hit in 31,850,051 MEDLINE articles (0.20 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
MAPK
30542
p38
22730
ERK1
22200
JNK
16370
ERK
13210
extracellular signal-regulated kinase
12069
Mol
11016
MAP kinase
8816
MEK
6851
mitogen-activated protein
6382
Sep
6225
cytokine
5952
PI3K
5145
c-Jun
5022
AKT
4957
caspase-3
4383
TNF
4243
p38 mitogen-activated protein kinase
3919
insulin
3869
IL-6
3678
tumor necrosis factor
3427
lipopolysaccharide
3245
ERK2
3123
MEK1
3063
p53
2993
Bcl-2
2944
tyrosine kinase
2885
mTOR
2647
phosphatidylinositol 3-kinase
2594
phosphatase
2497
AP-1
2488
collagen
2185
p42
2166
p65
2093
p44
2091
epidermal growth factor receptor
2080
extracellular signal-regulated kinase 1
2056
PKC
1996
BRAF
1952
inducible nitric oxide synthase
1929
MAP
1906
epidermal growth factor
1899
LPS
1798
IL-8
1763
JNK1
1699
p21
1653
TLR4
1565
protein kinase B
1539
threonine
1533
STAT3
1527
ATP
1495
ROS
1484
cyclooxygenase-2
1423
endoplasmic reticulum
1390
EGFR
1365
vascular endothelial growth factor
1347
cyclin D1
1340
STAT
1334
Raf-1
1318
matrix metalloproteinase
1297
chemokine
1287
TNF-alpha
1286
EGF
1211
interleukin-6
1173
p38 MAP kinase
1147
cytochrome c
1138
phosphoinositide 3-kinase
1121
Rho
1088
COX-2
1080
receptor tyrosine kinase
1034
c-fos
1033
CREB
1027
IL-10
1018
P38
1017
PARP
997
angiotensin II
996
p38MAPK
994
PKA
977
MMP-9
972
fibronectin
966
estrogen receptor
938
IFN
912
catenin
904
caspase-9
897
VEGF
865
EGF receptor
846
Ang II
842
proteasome
830
nerve growth factor
819
superoxide dismutase
812
caspase-8
804
focal adhesion kinase
801
platelet-derived growth factor
800
brain-derived neurotrophic factor
792
nitric oxide synthase
792
PI3
788
AMP
785
IRS-1
780
ubiquitin
766
catalase
766
GSH
760
calmodulin
754
RAF
748
TLR2
742
interferon
738
THP
734
GTP
718
E-cadherin
717
IL-1
711
ras
704
MEKK
701
heme oxygenase-1
686
KRAS
686
MMP-2
682
MKK4
680
insulin receptor
679
CD4
667
RhoA
620
p27
618
osteogenic
614
Nrf2
608
tumor necrosis factor alpha
607
histone
607
GTPase
600
Fas
585
cyclin
584
c-Src
580
JNK2
576
G protein-coupled receptor
572
GSK
571
AMPK
569
erythroid
559
PKB
549
IL-4
549
alkaline phosphatase
548
FAK
543
PTEN
538
MCP-1
532
TGF-beta
532
insulin-like growth factor
529
PDGF
526
cyclooxygenase
525
RANKL
523
proliferating cell nuclear antigen
523
AMP-activated protein kinase
521
annexin V
519
adaptor protein
519
IL-2
519
leptin
515
thrombin
501
serine/threonine kinase
499
JAK2
493
MyD88
487
FGF
487
IKK
482
hepatocyte growth factor
480
Smad2
479
HER2
468
PLC
464
calcineurin
463
ATPase
457
MKK3
449
Cytokine
447
peroxisome proliferator-activated receptor
441
STAT1
440
protein phosphatase
435
gut
433
CA1
430
IFN-gamma
426
adenylyl cyclase
425
glycoprotein
421
c-Myc
420
phosphorylating
416
ICAM-1
415
axonal
413
PP2
413
arrestin
412
IL-17
402
endothelin-1
401
SOD
401
extracellular signal regulated kinase
401
MEKK1
401
STAT5
399
lactate dehydrogenase
397
MKP-1
397
IGF-I
394
LC3
391
neurotrophin
388
ATF
388
signal transducer and activator of transcription 3
386
Tumor necrosis factor
385
IkappaBalpha
385
ASK1
384
interacting protein
382
HO-1
376
SHP-2
376
CXCR4
375
TCR
375
protein tyrosine phosphatase
374
VEGFR2
373
NRAS
372
proto-oncogene
369
CHOP
368
CD40
366
vimentin
366
myeloperoxidase
364
peroxisome proliferator-activated receptor gamma
362
mast cell
361
ribosomal S6 kinase
361
Smad3
361
amyloid precursor protein
358
CCL2
357
lymphoid
355
CD8
355
metalloproteinase
354
MKK6
353
ERK5
351
H-ras
350
SMA
349
vascular cell adhesion molecule-1
348
tyrosine phosphatase
347
NS5
347
histone deacetylase
347
MMP9
346
Sp1
345
cyclin-dependent kinase
345
phospholipase
344
IGF-1
342
Janus kinase
341
myelin basic protein
339
cAMP response element-binding protein
334
p70
334
protein tyrosine kinase
334
poly(ADP-ribose) polymerase
331
p50
330
heat shock protein
329
MMP-1
328
TAK1
325
cyclin E
325
glial fibrillary acidic protein
323
beta-catenin
322
TNF receptor
322
p85
320
TRAF6
319
MKK7
318
NMDA receptor
318
ADP
317
osteosarcoma
315
fused
311
Mcl-1
310
membrane protein
309
MEK2
307
glutathione peroxidase
307
S6K1
306
paxillin
305
CDK4
304
CD44
303
c-myc
302
small GTPase
302
histone H3
302
transforming growth factor-beta
301
monocyte chemoattractant protein-1
298
polypeptide
298
osteocalcin
298
IgE
296
urokinase-type plasminogen activator
295
smooth muscle actin
295
adhesion molecule
294
MAPK/ERK kinase
294
CaMKII
291
apoptosis signal-regulating kinase 1
290
adenylate cyclase
290
p90
290
renin
289
adiponectin
288
kit
285
CXCL12
283
T cell receptor
283
erbB-2
282
PI3-kinase
281
caveolin-1
280
membrane-bound
278
proteasome inhibitor
278
G-protein-coupled receptor
278
HEK
277
RANTES
277
phosphoprotein
275
CD14
273
androgen receptor
273
p62
273
PP1
271
N-cadherin
268
MAP2K1
265
macrophage colony-stimulating factor
265
cyclin B1
262
type I collagen
262
tyrosine hydroxylase
260
MMP
260
survivin
260
CCK
259
eNOS
257
Leptin
255
endothelial nitric oxide synthase
252
Pseudomonas
252
osteopontin
251
bradykinin
251
UTR
249
cAMP-dependent protein kinase
249
interferon-gamma
245
Met
244
glutathione S-transferase
244
NAC
243
glucocorticoid receptor
241
CDK2
238
mucin
238
GST
237
EBP
234
CD86
234
PC-3
234
A431
233
more...
Disease
cancer
14230
tumor
10060
breast cancer
3003
tumorigenesis
2221
tumor growth
2193
melanoma
1960
diabetes
1719
ischemia
1638
hepatocellular carcinoma
1601
carcinoma
1595
Alzheimer's disease
1485
carcinogenesis
1484
tumor progression
1355
atherosclerosis
1330
obesity
1243
leukemia
1224
lung cancer
1217
MCF
1177
prostate cancer
1029
pertussis
994
colorectal cancer
989
adenocarcinoma
976
hypertension
921
neuroblastoma
870
glioma
830
colon cancer
813
GSH
760
Parkinson's disease
725
asthma
675
metastases
668
type 2 diabetes
647
squamous cell carcinoma
636
rheumatoid arthritis
632
gastric cancer
628
ovarian cancer
625
stroke
618
non-small cell lung cancer
596
depression
577
glioblastoma
554
Blocking
545
pancreatic cancer
544
heart failure
525
sepsis
521
sepsis
506
acute myeloid leukemia
492
osteoporosis
469
ATM
454
hyperglycemia
452
HIV
446
multiple myeloma
439
arthritis
430
lymphoma
428
cerebral ischemia
419
cardiovascular disease
404
osteoarthritis
376
myocardial infarction
373
infectious diseases
370
B-cell lymphoma
366
virus infection
364
osteosarcoma
348
retinoblastoma
339
liver cancer
335
colitis
325
lung carcinoma
312
cold
311
pheochromocytoma
308
cognitive impairment
296
chronic myeloid leukemia
293
Mycobacterium
293
diabetic nephropathy
292
myocardial ischemia
282
Melanoma
281
plaque
276
chronic obstructive pulmonary disease
269
metastatic melanoma
264
liver cancer
262
bladder cancer
252
tumor angiogenesis
249
skin cancer
246
inflammatory bowel disease
243
immunodeficiency
241
sarcoma
240
tuberculosis
240
multiple sclerosis
239
Infection
237
thyroid cancer
235
cervical cancer
232
liver fibrosis
227
bacterial infection
227
metabolic syndrome
223
fatty liver
211
renal disease
210
psoriasis
210
dementia
209
MIP
200
renal cell carcinoma
195
epithelial ovarian cancer
191
astrocytoma
187
Epstein
186
NAME
183
glioblastoma multiforme
182
aggressiveness
181
periodontitis
180
SDS
180
Hepatocellular carcinoma
177
Leukemia
177
AGS
176
autoimmune disease
171
epilepsy
167
cardiomyopathy
166
fibrosarcoma
162
brain tumor
162
acute promyelocytic leukemia
161
schizophrenia
160
HGF
160
NOD
159
pulmonary fibrosis
157
vascular disease
156
systemic lupus erythematosus
153
primary tumor
152
SCID
151
hyperinsulinemia
148
hepatitis B
147
proteinuria
147
influenza
147
cirrhosis
146
endometrial cancer
146
atopic dermatitis
143
uterus
142
chronic pain
139
addiction
136
diabetic retinopathy
133
APC
132
dermatitis
132
papillary thyroid cancer
131
mammary tumor
129
myeloid leukemia
128
DDP
127
liver disease
126
Adhesion
124
chronic lymphocytic leukemia
124
neoplastic transformation
123
memory impairment
123
neurofibromatosis type 1
123
acute lymphoblastic leukemia
121
amyotrophic lateral sclerosis
121
pulmonary hypertension
121
heart disease
121
encephalomyelitis
121
hepatitis C
120
tumor initiation
119
Crohn's disease
117
type 1 diabetes
115
AIDS
113
pneumonia
112
EMT
111
oral cancer
111
ABL
111
hepatitis
110
dysplasia
109
anthrax
108
Huntington's disease
106
ulcerative colitis
104
cholera
104
glucose intolerance
102
coronary artery disease
102
endometriosis
101
solid tumor
99
chronic lymphocytic leukemia
99
Kaposi's sarcoma
99
adenoma
97
lung disease
95
polycystic kidney
95
hyperlipidemia
94
brain edema
94
leukemogenesis
93
autism
93
glomerulosclerosis
93
cystic fibrosis
93
Osteosarcoma
92
Osteosarcoma
92
renal failure
91
worms
91
tuberous sclerosis
90
preeclampsia
89
anemia
89
Costello syndrome
89
malnutrition
89
pulmonary edema
89
acute myocardial infarction
89
cutaneous melanoma
88
skin disease
88
neuropathy
87
mole
87
herpes simplex
86
esophageal cancer
86
dyslipidemia
85
Steroids
85
malaria
85
Glioblastoma
85
MTS
85
infertility
84
Evans
83
ventricular hypertrophy
82
acute pancreatitis
82
Hodgkin's disease
81
insulinoma
81
periodontal disease
80
FAS
80
anaphylaxis
79
mental retardation
79
cornea
79
choriocarcinoma
79
idiopathic pulmonary fibrosis
79
lupus
79
vaccinia
78
mental retardation
78
esophageal cancer
78
cytomegalovirus
77
pancreatitis
77
glomerulonephritis
77
Adenovirus
76
myeloproliferative disorders
76
hematologic malignancies
76
Pineal
73
hypertrophic cardiomyopathy
73
dilated cardiomyopathy
73
muscular atrophy
73
Langerhans cell histiocytosis
72
Yersinia
71
genetic disorder
71
metastatic breast cancer
71
lupus
70
small cell lung cancer
70
erythroleukemia
69
macular degeneration
69
subarachnoid hemorrhage
69
rhabdomyosarcoma
65
medulloblastoma
65
hypercholesterolemia
65
TAM
64
diabetic cardiomyopathy
64
renal ischemia
64
mastitis
64
aggression
63
HCC
63
myelodysplastic syndrome
63
glaucoma
63
mesothelioma
62
blindness
62
skin tumor
62
retinopathy
61
chronic hepatitis
61
bone disease
61
drug addiction
61
Cryptococcus neoformans
61
thymoma
60
pruritus
60
neurofibromatosis
60
coronary heart disease
59
Burkitt's lymphoma
59
chondrosarcoma
59
CEP
58
polycystic ovary syndrome
58
bipolar disorder
57
chronic renal failure
57
renal cancer
56
Neuroblastoma
56
Neuroblastoma
56
anaplastic thyroid cancer
55
disc degeneration
55
peripheral neuropathy
54
myocarditis
54
developmental delay
53
major depressive disorder
53
CCL
53
Placenta
52
Brown
52
cerebral infarction
52
HSP
52
ARF
51
lung metastases
51
WT1
50
fungal infection
50
hyperhomocysteinemia
50
abortion
50
congestive heart failure
49
FBS
49
arthropathy
48
medullary thyroid carcinoma
48
PTP
48
PHA
48
meningitis
48
parkinsonism
48
metabolic disorder
47
Recruitment
47
head and neck cancer
47
Tumour necrosis
47
Nonalcoholic fatty liver
46
emphysema
46
endotoxic shock
46
INS
46
Thyroid cancer
46
SARS
46
Hippel
46
mole
45
JIP
45
encephalitis
45
DSS
44
Ewing's sarcoma
44
COPD
43
cholestasis
43
wasting
43
Nasopharyngeal carcinoma
43
Frey
43
LTD
42
Chlamydia
42
stromal tumors
42
DSS
41
dyskinesia
41
more...
Symptom
pain
923
starvation
395
seizures
202
functional recovery
145
diarrhea
132
collapse
115
anesthesia
79
respiratory distress
78
analgesia
75
hyperoxia
73
hypothermia
62
fatigue
62
skin damage
62
headache
45
Neuropathic pain
42
cachexia
42
exhaustion
41
acute stress
39
memory loss
35
weakness
34
splenomegaly
34
ataxia
31
erythema
31
cough
29
overweight
28
arthralgia
25
thinning
24
nausea
23
bone pain
23
vomiting
21
low back pain
21
angina
18
anorexia
18
Scratch
16
dyspnea
15
pelvic pain
14
dry eye
14
despair
14
hypotonia
14
tremor
13
HSA
13
hypercapnia
12
abdominal pain
12
constipation
11
Inflammatory pain
11
back pain
11
hepatomegaly
10
myalgia
10
cancer pain
9
acidity
9
orofacial pain
9
acute pain
9
hepatosplenomegaly
9
insomnia
7
spasm
7
dry skin
7
flushing
6
sore throat
6
bradykinesia
6
neurological disability
6
fasciculation
6
incoordination
6
menopausal symptoms
6
skin irritation
6
stigma
5
discomfort
5
discomfort
5
distraction
5
twitching
5
chest pain
5
agitation
5
decreased appetite
5
lethargy
5
dizziness
5
bladder pain
5
numbness
5
muscle cramps
5
neuralgia
4
microbial colonization
4
wheezing
4
Depressive symptoms
4
cerebellar ataxia
4
dystonia
4
Anoxia
4
scaly skin
3
facial pain
3
Wind
3
impaired motor coordination
3
polyuria
3
vertigo
3
myoclonus
3
sciatica
3
masculinization
3
nasal congestion
3
muscle stiffness
3
Ear swelling
3
polydipsia
3
spasticity
3
dental pain
3
nausea and vomiting
3
tinnitus
3
rundown
2
paresthesia
2
asthenia
2
Halo
2
Mills
2
Noise-induced hearing loss
2
Macula
2
hoarseness
2
hemiplegia
2
hunger
2
ACHE
2
Organ failure
2
chills
2
ENT
2
ataxic gait
2
paraparesis
2
chorea
2
Decreased activity
2
rhinorrhea
2
sleepiness
2
swollen joints
2
dysarthria
2
regurgitation
2
paresis
2
Ill
2
loss of balance
2
bitter taste
2
female puberty
2
bedwetting
1
impaired body balance
1
abnormal gait
1
bradypnea
1
disturbed balance
1
tonic-clonic seizure
1
Hudson
1
stomach cramps
1
halitosis
1
periorbital edema
1
SYMPTOMS
1
GI irritation
1
heartburn
1
Motor dysfunction
1
Behavioral symptoms
1
hemoptysis
1
night sweats
1
male subfertility
1
Incisional pain
1
prostration
1
livedo
1
hot flashes
1
Bladder distention
1
POA
1
delayed language development
1
Thalamic pain
1
forgetfulness
1
eye pain
1
colic
1
catatonia
1
Catch
1
Visceral pain
1
muscle rigidity
1
abdominal cramps
1
Mechanical pain
1
Central post-stroke pain
1
catarrh
1
neck pain
1
sneezing
1
CSR
1
Mucosal hyperplasia
1
photophobia
1
stomach pain
1
chronic back pain
1
exertional dyspnea
1
chronic cough
1
chronic constipation
1
ophthalmoplegia
1
dysesthesia
1
skin irritant
1
pallor
1
motor symptom
1
syncope
1
cardiovascular problem
1
dysuria
1
otalgia
1
anosmia
1
hopelessness
1
emaciation
1
Fluctuation
1
Drug
MAP
1988
ROS
1484
Dermatol
541
IL-2
519
IFN-gamma
421
lysine
369
CSF
368
Angiotensin II
344
ICI
251
Cardiovasc
212
p75
164
ETS
161
Sorafenib
131
Monit
128
vitamin E
124
ascorbate
121
caffeine
119
Gefitinib
114
Ethanol
112
Arsenic trioxide
99
EE2
94
Heme
92
Forskolin
89
Gel
88
uPA
86
Taxol
83
IFN-beta
73
Imatinib
71
TAK
69
Herceptin
69
Retinoic acid
64
Activin
63
ETA
63
NVP
61
TAT
61
Simvastatin
61
NADH
60
Estrogens
59
G-CSF
58
Glutathione
58
Indomethacin
56
Asthma
53
Nitric Oxide
53
GEO
53
IL-11
53
CCL
53
PTH
51
Glucagon
51
Histamine
50
Cetuximab
50
Gelatin
50
Nephron
50
Ouabain
49
ADR
49
CTX
49
Rosiglitazone
44
Growth hormone
44
PTC
44
Growth hormone
44
Asn
43
Gleevec
43
Glycyrrhiza
41
Bortezomib
41
Epigallocatechin
41
Erlotinib
40
ABC
40
Lovastatin
38
MRC
37
CAM
36
Leaf
34
Emodin
34
Emodin
34
Parkin
32
Propofol
32
Parkin
32
PCP
32
Portal
31
Dasatinib
30
IL-1ra
29
CTX
28
Albumin
28
Ginseng
28
CTX
27
Bifidobacterium
27
Mutagen
27
CoCl2
26
CoCl2
26
Adriamycin
24
Docetaxel
24
lactose
24
Fulvestrant
24
K-252a
23
Vitamin E
23
EPA
23
PFT
22
ZnO
22
Myricetin
22
GHRP
22
Rutin
21
TiO2
21
nitroglycerin
20
DEX
19
Alanine
19
Oxaliplatin
19
DNase I
19
RAL
18
Pravastatin
18
TEL
17
-deoxyadenosine
17
Troglitazone
17
Silica
17
KGF
16
Etoposide
16
ALA
16
Bevacizumab
16
Glycerol
16
Rituximab
16
Tarceva
16
ADM
16
Fluorescein
16
GRF
15
Liraglutide
15
Photofrin
15
citric acid
15
G418
14
Kenyan
14
DHT
14
Doxycycline
14
TTC
14
CED
14
RFP
14
DHT
14
2-Methoxyestradiol
13
Capsicum
13
Olmesartan
13
Paraffin
13
ROC
13
PDL
13
3-Methyladenine
13
Ciglitazone
13
Triclosan
13
Everolimus
12
Zoledronic acid
12
BH4
12
niacin
12
Ginger
12
Rosuvastatin
12
NBT
12
FAD
12
ENT
11
Vandetanib
11
HCH
11
Fructose
11
Amiloride
11
Raloxifene
11
DMAP
11
Cilostazol
11
Salicylate
10
Luteinizing
10
AMC
10
Alliance
10
Sodium nitroprusside
10
Flavopiridol
10
Vitamin A
10
Nexavar
10
Kainic acid
10
Itraconazole
10
Fluorescein
10
PCB
9
CaCl2
9
pyridoxal phosphate
9
Tocopherol
9
MDS
9
9-THC
9
CaCl2
9
CaCl2
9
TAC
9
Fraction
9
R1881
9
Adenosine triphosphate
9
BLM
9
Doyle
8
Vitamin K
8
Aliskiren
8
Sesamol
8
Vorinostat
8
Tranilast
8
Mycophenolic acid
8
Spectrum
8
Casodex
8
Rolipram
8
ID2
8
VCR
8
AraC
8
Artesunate
7
Zoledronic acid
7
Verteporfin
7
Red ginseng
7
Ezetimibe
7
Limonene
7
Nephron
7
Amiloride
7
Ulinastatin
7
Imiquimod
7
Orphan
7
Acacia
7
Tipifarnib
7
Donepezil
7
Ipilimumab
7
Rasagiline
7
TMS
6
Tannic acid
6
Dihydro
6
PFA
6
Bromelain
6
Dial
6
Scopolamine
6
Theophylline
6
ZnCl2
6
Biopolymers
6
Pirfenidone
6
Fentanyl
6
CIA
6
ZnCl2
6
Anakinra
6
Captopril
6
Dihydrotestosterone
6
CPT-11
6
Panitumumab
6
Phosphatidylserine
6
Pemetrexed
6
Areca
5
Olomoucine
5
NOV
5
Romidepsin
5
Bumetanide
5
Azithromycin
5
PNT
5
Glide
5
Exenatide
5
Valsartan
5
Benfotiamine
5
Pertuzumab
5
VCR
5
Norplant
5
AIC
5
Urokinase
5
PDGF B-chain
5
SiO2
5
MTC
5
Fragment
5
Isoniazid
5
Iloprost
5
BoNT/A
5
Tocilizumab
5
Tianeptine
5
NAG
5
Radicicol
5
Apomorphine
5
BTC
5
Tao
5
MDM
5
Taxotere
5
FeCl3
5
Sunitinib malate
4
Tolfenamic acid
4
Fluticasone propionate
4
Atropine
4
Cetrorelix
4
Iodixanol
4
Glutamic acid
4
Trapidil
4
Roflumilast
4
Palmitoyl
4
Clopidogrel
4
Secretin
4
Safflower
4
ACT
4
AZT
4
DEL
4
Lenalidomide
4
Bupivacaine
4
Vinorelbine
4
AZT
4
Caspofungin
4
Roflumilast
4
Ranitidine
4
Amlexanox
4
Vitamin K2
4
Prednisolone
4
Xanthium
4
CTC
4
Marimastat
4
Crystal Violet
4
Tykerb
4
Aloe
4
CTC
4
Isotretinoin
4
Abamectin
4
Scutellaria root
4
Bosutinib
4
Ringer's solution
4
Aminoguanidine
4
Micafungin
4
Hypaque
3
Propidium
3
Domin
3
Hyaluronidase
3
Artemether
3
Ketoconazole
3
Mevastatin
3
Colistin
3
Allergen
3
Epalrestat
3
Febuxostat
3
CDP
3
Tolvaptan
3
THF
3
Bosentan
3
Cinacalcet
3
more...
Enzyme
mitogen-activated protein kinase
95810
ERK
16661
MEK
10639
protein kinase
8941
protein kinase C
5579
caspase-3
3450
focal adhesion kinase
3173
phosphatidylinositol 3-kinase
2598
MAP
1909
luciferase
1613
MEKK1
1152
phosphoinositide 3-kinase
1121
PARP
1114
superoxide dismutase
1114
calcineurin
1083
NADPH oxidase
1072
AMP-activated protein kinase
1050
phospholipase C
1048
NADPH oxidase
948
catalase
894
proteasome
848
AMPK
817
IKK
725
caspase-9
721
GSK
642
caspase-8
613
cdc2
607
NO synthase
597
collagenase
571
AMPK
570
alkaline phosphatase
549
ATPase
502
thrombin
494
glutathione S-transferase
474
peroxidase
464
phospholipase A2
455
lactate dehydrogenase
412
CaMKII
385
urokinase-type plasminogen activator
342
alanine aminotransferase
339
adenylate cyclase
315
glutathione peroxidase
314
renin
289
protein phosphatase 2A
281
MMP
270
aspartate aminotransferase
268
tyrosine hydroxylase
250
caspase-1
232
MMP-3
224
reverse transcriptase
224
phosphodiesterase
223
heme oxygenase
205
MIP
200
RNA polymerase
191
tyrosinase
190
NOS
190
APC
188
PKG
181
phospholipase D
176
PDK1
175
ACS
175
guanylate cyclase
165
trypsin
163
cathepsin K
157
P-glycoprotein
154
NQO1
129
myosin light chain kinase
127
acetylcholinesterase
117
matrix metalloproteinase 9
110
GRK5
106
complex I
103
AST
103
DCF
99
farnesyltransferase
99
lipoxygenase
98
sphingosine kinase
98
creatine kinase
98
MPP
97
xanthine oxidase
97
glutathione reductase
92
farnesyltransferase
90
tissue plasminogen activator
88
histidine kinase
86
kinesin
84
TOR
83
GRK2
83
topoisomerase
82
acetyl-CoA carboxylase
80
caspase-7
75
caspase-7
75
matrix metalloproteinase 2
75
topoisomerase
74
ACE
74
PTPase
74
RNase
70
ornithine decarboxylase
70
hexosaminidase
69
lipase
68
RNase
66
beta-galactosidase
65
elastase
64
hormone-sensitive lipase
64
cathepsin B
62
TAT
61
inositol 3-kinase
60
CPT
59
CEP
59
histone acetyltransferase
58
gamma-glutamylcysteine synthetase
58
CEP
58
plasmin
57
TdT
56
CD10
55
arginase
55
neutrophil elastase
54
acid phosphatase
54
peroxiredoxin
53
aldose reductase
52
phosphoenolpyruvate carboxykinase
51
CPT
51
CPT
50
TACE
50
succinate dehydrogenase
49
thioredoxin reductase
49
DNA methyltransferase
47
choline acetyltransferase
47
polo-like kinase 1
46
transcriptase
46
interstitial collagenase
46
lysozyme
45
lipoprotein lipase
44
neutral sphingomyelinase
44
neuraminidase
42
glyceraldehyde-3-phosphate dehydrogenase
42
furin
42
tryptase
41
aldehyde dehydrogenase
40
triphosphatase
39
cathepsin D
39
HSD
39
chloramphenicol acetyltransferase
39
phosphoenolpyruvate carboxykinase
38
thromboplastin
38
phosphoenolpyruvate carboxykinase
38
caspase-2
37
kallikrein
37
prostate-specific antigen
37
caspase-2
36
caspase-4
36
transglutaminase
35
aldehyde dehydrogenase
34
PDE
34
granzyme B
34
aldehyde dehydrogenase
33
aldehyde dehydrogenase
33
aldehyde dehydrogenase
33
monoamine oxidase
33
caspase-4
33
PCP
32
15-lipoxygenase
32
phosphatidylinositol-4,5-bisphosphate 3-kinase
32
lysyl oxidase
31
PI-PLC
30
glutamine synthetase
29
12-lipoxygenase
29
prostaglandin synthetase
28
cellulose synthase
28
CYP7A1
28
hyaluronidase
28
sialidase
27
cholinesterase
27
p100
27
chitinase
26
diacylglycerol kinase
26
glyceraldehyde-3-phosphate dehydrogenase
26
ECH
26
CLK1
26
factor C
26
eEF2 kinase
26
m-calpain
25
AMP-activated kinase
25
hexokinase
25
DNA polymerase
25
glycerol-3-phosphate dehydrogenase
24
glycerol-3-phosphate dehydrogenase
24
CD13
24
inositol phosphatase
24
hyaluronidase
24
ribonucleotide reductase
24
adenosine deaminase
23
glucokinase
23
adenosine deaminase
23
enolase
23
apyrase
23
glucose oxidase
23
firefly luciferase
23
ribonucleotide reductase
23
pyruvate dehydrogenase
22
gamma-glutamyl transpeptidase
22
mu-calpain
21
endonuclease
21
ceramidase
21
ATP synthase
21
cathepsin L
21
thymidine kinase
20
caspase-6
20
phosphatidylinositol 4-kinase
20
glyceraldehyde-3-phosphate dehydrogenase
20
histidine decarboxylase
20
glucosylceramide synthase
20
angiotensin-converting enzyme 2
20
caspase-6
20
prolidase
19
CAD
19
MDR
19
15-hydroxyprostaglandin dehydrogenase
19
glyceraldehyde-3-phosphate dehydrogenase
19
glyceraldehyde-3-phosphate dehydrogenase
19
citrate synthase
19
CAD
19
alcohol dehydrogenase
19
prolyl hydroxylase
19
phosphorylase
19
CAD
19
GAS
19
adenosine kinase
18
BAL
18
glucose-6-phosphatase
18
pyruvate dehydrogenase
18
tissue kallikrein
18
3-hydroxy-3-methylglutaryl coenzyme A reductase
18
soluble epoxide hydrolase
18
demethylase
18
pyruvate dehydrogenase
18
glucose-6-phosphate dehydrogenase
17
SPT
17
sialyltransferase
17
sialyltransferase
17
HK2
17
sialyltransferase
17
pyruvate kinase
17
thyroid peroxidase
17
cytochrome oxidase
17
chymase
17
ribonuclease
17
ribonuclease
17
CYP3A4
16
PAL
16
carbonic anhydrase
16
papain
16
ricin
16
indoleamine 2,3-dioxygenase
16
PRE
15
PAH
15
chymotrypsin
15
O-GlcNAc transferase
15
endothelin-converting enzyme
15
ascorbate peroxidase
14
beta-secretase
14
GalT
14
tryptophan hydroxylase
14
HCS
14
phosphofructokinase
14
cholesterol acyltransferase
14
peptidyl-prolyl cis-trans isomerase
14
proteinase K
13
sulfatase
13
laccase
13
diaphorase
13
LPL
13
TSP-1
13
TSA
13
3beta-hydroxysteroid dehydrogenase
12
proprotein convertase
12
Thy1
12
FPS
12
PAL
12
insulin-degrading enzyme
12
thymidylate synthase
12
3-hydroxy-3-methylglutaryl-CoA reductase
12
nicotinamide phosphoribosyltransferase
12
DNA ligase
12
DNA ligase
12
NSY
12
callose synthase
11
MDP
11
biliverdin reductase
11
isopeptidase
11
glutathione synthetase
11
protein farnesyltransferase
11
N-acetyltransferase
11
Omi/HtrA2
11
heparinase
11
aconitase
11
SPC
11
p80
11
CPS
11
ALDH
11
cathepsin G
11
dipeptidyl peptidase IV
10
ADP-ribosyltransferase
10
chitin synthase
10
ubiquitin-protein ligase
10
chaperonin
10
ADP-ribosyltransferase
10
D-dopachrome tautomerase
10
dihydrofolate reductase
10
glutaminase
10
subtilisin
9
sucrase-isomaltase
9
PAM
9
nitrate reductase
9
cGMP phosphodiesterase
9
ceruloplasmin
9
cathepsin S
9
myosin ATPase
9
matriptase
9
Protein 2
9
sucrase
9
cellulase
9
more...
Compound
DNA
7460
Dec
6800
oxygen
6780
MEK
6032
tyrosine
5762
calcium
4543
TNF
4243
glucose
3076
serine
2693
cAMP
2673
nitric oxide
2498
threonine
2301
MAP
1912
acetate
1741
Clin
1531
ATP
1499
sodium
1325
MTT
1324
water
1271
cysteine
1242
phosphate
1198
hydrogen
1106
MDA
1053
glutamate
970
NH2
911
N-acetylcysteine
838
AMP
822
Insulin
818
GSH
795
GSH
795
THP
736
THP
735
GTP
720
H2O2
718
alanine
683
arginine
654
PGE
645
Ang II
639
ethanol
633
methionine
591
leucine
576
lysine
550
sulfate
528
PMA
465
PMA
451
retinoic acid
451
Phe
435
nitrogen
430
Angiotensin II
419
salt
416
cGMP
413
glycerol
399
bromide
397
zinc
396
ATF
388
galactose
375
Cardiol
372
ADP
363
proline
355
iodine
352
PGE2
350
NMDA
350
iron
350
potassium
347
COS
340
Asp
332
dUTP
331
ADP
320
ADP
317
Curcumin
294
5-HT
274
urea
263
cadmium
261
ICI
252
Panam
244
Wortmannin
237
NAD
231
Resveratrol
230
Tyrosine
219
ADP-ribose
210
aldosterone
202
DDP
202
Estrogen
196
Gly
194
His
193
pyrimidine
193
nicotinamide
192
Estrogen
192
boron
191
pyrimidine
188
ASA
188
creatinine
187
salicylic acid
185
SDS
183
vitamin D
182
TPA
179
BCR
179
TPA
179
palmitic acid
177
NADPH
176
GDP
175
ACS
175
NADPH
175
pyrrolidine
175
ACS
175
Neuronal
166
Melatonin
166
NAD
166
Phosphatidylinositol
164
Rapamycin
163
APAP
158
glutamine
155
Quercetin
153
diacetate
153
pyrrolidine
152
AMPA
149
Thrombin
147
copper
147
H2S
145
CO2
142
Genistein
141
CAT
140
CAT
139
Cbl
139
CAT
139
Estradiol
136
GABA
135
ADR
135
Serine
134
GABA
131
Collagen
131
PEG
129
ALP
129
1H-imidazole
129
MPTP
128
aldehyde
128
DMSO
127
manganese
127
selenium
125
ethyl acetate
123
ABL
120
caffeine
120
HOG
116
prostacyclin
116
UTP
114
tryptophan
112
Glutamate
110
Adriamycin
110
aldehyde
109
Adenosine
108
PLA
107
glutamic acid
107
acetic acid
104
Cer
104
noradrenaline
104
aspartic acid
103
1H-imidazole
102
pyridine
102
FK506
100
palmitic acid
99
LY 294002
97
kaempferol
97
MPP
97
MPP
97
Vimentin
97
titanium
96
Dexamethasone
96
methanol
95
homocysteine
94
Heme
93
cobalt
92
GSSG
91
TEM
91
GAP
90
Thyroid
89
Forskolin
89
Progesterone
88
PEG
86
Berberine
85
Metformin
85
Metformin
85
aspartic acid
85
Cereb
84
MTS
84
ammonium
84
Ile
82
ACTH
81
silver
81
GMP
81
adenylate
81
1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine
80
aspartic acid
79
aspartic acid
79
STZ
79
4-chlorophenyl
77
Luteolin
77
4-chlorophenyl
77
TNM
76
tryptophan
76
Pac
76
Retinal
75
COX
75
uridine
75
Sphingosine
75
GF 109203X
74
tryptophan
73
Nicotine
73
tryptophan
73
Tamoxifen
73
anthracene
72
Tamoxifen
72
L-DOPA
71
Cholesterol
71
phosphoserine
71
hyaluronic acid
70
Isoproterenol
70
TOF
70
chalcone
70
Bisphenol A
69
pyrene
69
SCC
69
Dopamine
69
H2S
69
Bisphenol A
69
Arsenic
68
nitrate
68
isoquinoline
68
valine
67
superoxide radical
67
Morphine
66
naphthoquinone
65
naphthoquinone
65
naphthoquinone
65
naphthoquinone
65
Hoechst 33342
65
naphthoquinone
65
naphthoquinone
65
8-OHdG
65
naphthoquinone
65
ETA
65
Tanshinone
63
Histone
63
Phorbol
63
gallic acid
63
phenol
63
DBA
62
adenosylmethionine
62
fluorine
62
TSH
61
NADH
60
Anisomycin
60
DPI
59
hydroxide
58
Arachidonic acid
57
Cycloheximide
57
Silymarin
57
ACh
57
Paclitaxel
57
2-nonenal
57
GlcNAc
56
5-FU
56
MIA
55
Baicalein
55
tin
54
Mg2+
54
AICAR
54
Vitamin D
54
DHA
54
Sphingosine 1-phosphate
54
acridine
54
tert-butyl hydroperoxide
54
Staurosporine
53
Staurosporine
53
Apigenin
52
CoA
52
Emodin
52
Sulforaphane
52
gamma-aminobutyric acid
52
nickel
52
butyric acid
52
ABA
52
HCl
51
Guo
51
Hearts
51
PAR
51
Glucagon
51
TACE
51
Bradykinin
50
chromium
50
Epigallocatechin
50
Carbachol
50
CPT
50
Histamine
50
CPT
50
Epigallocatechin gallate
49
PGJ2
49
Ouabain
49
CTX
49
Heparin
49
Okadaic acid
48
TTC
48
Cyclosporine
48
mercury
48
Arsenite
48
Glycogen synthase
47
GM1
47
Hematoxylin
47
BNP
46
CCl4
46
AICAR
46
Cyt
45
Hearts
45
bis(2-chloroethyl)
45
Phorbol 12-myristate 13-acetate
44
DEHP
44
ammonia
44
LTD
44
DPG
44
Leucine
43
VP-16
43
more...