Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: EC:2.7.11.24 (
mitogen-activated protein kinase
)
95,810
document(s) hit in 31,850,051 MEDLINE articles (0.07 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
MAPK
30542
p38
22730
ERK1
22200
JNK
16370
ERK
13210
extracellular signal-regulated kinase
12069
Mol
11016
MAP kinase
8816
MEK
6851
mitogen-activated protein
6382
Sep
6225
cytokine
5952
PI3K
5145
c-Jun
5022
AKT
4957
caspase-3
4383
TNF
4243
p38 mitogen-activated protein kinase
3919
insulin
3869
IL-6
3678
more...
Disease
cancer
14230
tumor
10060
breast cancer
3003
tumorigenesis
2221
tumor growth
2193
melanoma
1960
diabetes
1719
ischemia
1638
hepatocellular carcinoma
1601
carcinoma
1595
Alzheimer's disease
1485
carcinogenesis
1484
tumor progression
1355
atherosclerosis
1330
obesity
1243
leukemia
1224
lung cancer
1217
MCF
1177
prostate cancer
1029
pertussis
994
more...
Symptom
pain
923
starvation
395
seizures
202
functional recovery
145
diarrhea
132
collapse
115
anesthesia
79
respiratory distress
78
analgesia
75
hyperoxia
73
hypothermia
62
fatigue
62
skin damage
62
headache
45
cachexia
42
Neuropathic pain
42
exhaustion
41
acute stress
39
memory loss
35
splenomegaly
34
more...
Drug
MAP
1988
ROS
1484
Dermatol
541
IL-2
519
IFN-gamma
421
lysine
369
CSF
368
Angiotensin II
344
ICI
251
Cardiovasc
212
p75
164
ETS
161
Sorafenib
131
Monit
128
vitamin E
124
ascorbate
121
caffeine
119
Gefitinib
114
Ethanol
112
Arsenic trioxide
99
more...
Enzyme
mitogen-activated protein kinase
95810
ERK
16661
MEK
10639
protein kinase
8941
protein kinase C
5579
caspase-3
3450
focal adhesion kinase
3173
phosphatidylinositol 3-kinase
2598
MAP
1909
luciferase
1613
MEKK1
1152
phosphoinositide 3-kinase
1121
PARP
1114
superoxide dismutase
1114
calcineurin
1083
NADPH oxidase
1072
AMP-activated protein kinase
1050
phospholipase C
1048
NADPH oxidase
948
catalase
894
more...
Compound
DNA
7460
Dec
6800
oxygen
6780
MEK
6032
tyrosine
5762
calcium
4543
TNF
4243
glucose
3076
serine
2693
cAMP
2673
nitric oxide
2498
threonine
2301
MAP
1912
acetate
1741
Clin
1531
ATP
1499
sodium
1325
MTT
1324
water
1271
cysteine
1242
more...