Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:2.7.11.24 (mitogen-activated protein kinase)
95,810 document(s) hit in 31,850,051 MEDLINE articles (0.10 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
MAPK 30542
p38 22730
ERK1 22200
JNK 16370
ERK 13210
extracellular signal-regulated kinase 12069
Mol 11016
MAP kinase 8816
MEK 6851
mitogen-activated protein 6382
Sep 6225
cytokine 5952
PI3K 5145
c-Jun 5022
AKT 4957
caspase-3 4383
TNF 4243
p38 mitogen-activated protein kinase 3919
insulin 3869
IL-6 3678
more...
Disease
cancer 14230
tumor 10060
breast cancer 3003
tumorigenesis 2221
tumor growth 2193
melanoma 1960
diabetes 1719
ischemia 1638
hepatocellular carcinoma 1601
carcinoma 1595
Alzheimer's disease 1485
carcinogenesis 1484
tumor progression 1355
atherosclerosis 1330
obesity 1243
leukemia 1224
lung cancer 1217
MCF 1177
prostate cancer 1029
pertussis 994
more...
Symptom
pain 923
starvation 395
seizures 202
functional recovery 145
diarrhea 132
collapse 115
anesthesia 79
respiratory distress 78
analgesia 75
hyperoxia 73
hypothermia 62
fatigue 62
skin damage 62
headache 45
cachexia 42
Neuropathic pain 42
exhaustion 41
acute stress 39
memory loss 35
splenomegaly 34
more...
Drug
MAP 1988
ROS 1484
Dermatol 541
IL-2 519
IFN-gamma 421
lysine 369
CSF 368
Angiotensin II 344
ICI 251
Cardiovasc 212
p75 164
ETS 161
Sorafenib 131
Monit 128
vitamin E 124
ascorbate 121
caffeine 119
Gefitinib 114
Ethanol 112
Arsenic trioxide 99
more...
Enzyme
mitogen-activated protein kinase 95810
ERK 16661
MEK 10639
protein kinase 8941
protein kinase C 5579
caspase-3 3450
focal adhesion kinase 3173
phosphatidylinositol 3-kinase 2598
MAP 1909
luciferase 1613
MEKK1 1152
phosphoinositide 3-kinase 1121
PARP 1114
superoxide dismutase 1114
calcineurin 1083
NADPH oxidase 1072
AMP-activated protein kinase 1050
phospholipase C 1048
NADPH oxidase 948
catalase 894
more...
Compound
DNA 7460
Dec 6800
oxygen 6780
MEK 6032
tyrosine 5762
calcium 4543
TNF 4243
glucose 3076
serine 2693
cAMP 2673
nitric oxide 2498
threonine 2301
MAP 1912
acetate 1741
Clin 1531
ATP 1499
sodium 1325
MTT 1324
water 1271
cysteine 1242
more...