Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: EC:2.7.11.22 (
cdc2
)
8,319
document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
chaperonin 10-related protein
11.9
ORC3L
11.9
FAM103A1
11.9
ik3-2
11.9
STK25
11.9
SNXA
11.9
tumor necrosis factor type 1 receptor associated protein
11.9
protein kinase C inhibitor protein-1
11.9
CP110 protein
11.9
ORC1L
11.9
RINGO C
11.9
LOC441204
11.9
cdk2
11.9
cyclin-dependent kinase 6
11.9
STK25 protein
11.3
cdc2-related protein kinase
11.2
PCTAIRE
11.0
CAK1
10.9
WW-domain binding protein 2
10.9
PCTK3
10.9
minichromosome maintenance protein 4
10.9
SALL2 protein
10.9
MIF4G domain containing
10.9
STK24
10.9
cerebral cavernous malformation 2
10.9
wee1 tyrosine kinase
10.9
CGI-121
10.9
CYCB3
10.9
Male germ cell-associated kinase
10.9
NUMB isoform 1
10.9
PNQALRE
10.9
UBE2V
10.9
ZFP276
10.9
CCRK
10.9
serum amyloid A-like 1
10.9
Serologically defined colon cancer antigen 1
10.9
PISSLRE
10.8
Cyclin-dependent kinase 11
10.7
CDK3
10.6
Nin1p
10.6
cyclin T2a
10.6
p34
10.6
cdc25C protein
10.5
PCTK1
10.4
serine/threonine kinase 24
10.3
PITSLRE beta 1
10.3
cell division protein kinase 6
10.3
E2F transcription factor 6
10.3
CKS2 protein
10.3
serine/threonine protein kinase MST4
10.3
CNAP1
10.3
Cyclin-dependent kinase-like 2
10.3
SAAL1
10.3
minichromosome maintenance complex component 5
10.3
cycB2
10.3
PFTAIRE protein kinase 1
10.3
CDK-activating kinase
10.3
cyclin T2
10.1
NPAT
10.1
CAK
10.0
CHED
10.0
cyclin E
10.0
Cdc25B phosphatase
10.0
cyclin A
10.0
cdc25B
10.0
DDX49
9.9
RFC40
9.9
PAQR4
9.9
WD repeat and SOCS box-containing protein 1
9.9
NKIAMRE
9.9
synaptonemal complex protein 2
9.9
CRYBG3
9.9
CTTNBP2NL
9.9
THG-1
9.9
cdk inhibitor p27KIP1
9.9
NPDC-1 protein
9.9
FBL2
9.9
FAM133B
9.9
Cyclin-dependent kinases regulatory subunit 2
9.9
CDK5 protein
9.9
more...
Disease
CFM1
11.9
Congenital knee dislocation
10.3
CHED
9.3
MDD2
8.4
Acute glaucoma
8.2
retinoblastoma
7.9
Hereditary canine spinal muscular atrophy
7.9
esophageal irritation
7.6
Mesangioproliferative glomerulonephritis
7.6
CCM3
7.3
PCAP
7.3
EDS5
7.1
XPB
7.0
Dedifferentiated liposarcoma
6.8
mouse leukemia L1210
6.7
CHR
6.7
NINA
6.7
salivary gland adenoid cystic carcinoma
6.7
CLN1
6.6
CLN2
6.5
megalocytosis
6.5
Feline panleukopenia
6.4
XPD
6.3
benign ovarian cyst
6.2
Liver regeneration
6.2
STY
6.2
HFH
6.1
testicular choriocarcinoma
6.1
brittle hair
6.1
OCM
6.0
CCM2
6.0
adrenocortical cancer
6.0
culture shock
5.8
Renal interstitial fibrosis
5.8
CASS
5.8
Oral Cancer
5.8
EIC
5.6
Brachydactyly
5.6
HEP
5.6
large cell lung cancer
5.6
NLS
5.6
CRD1
5.5
western equine encephalomyelitis
5.5
endotheliosis
5.4
EL1
5.4
trichothiodystrophy
5.4
monocytic leukemia
5.3
AIDS-related malignancies
5.3
pseudopseudohypoparathyroidism
5.2
CLN3
5.0
XPG
5.0
adrenal cancer
4.9
Alveolar rhabdomyosarcoma
4.9
low-grade lymphomas
4.8
ATM
4.8
LIN
4.8
POH
4.8
MCPH1
4.8
vulval cancer
4.8
relapsed CLL
4.8
FANCJ
4.8
Shope fibroma
4.7
MDM
4.6
APC
4.6
Gingival overgrowth
4.6
AGS
4.6
PSN
4.6
CCA1
4.6
MCF
4.5
VES
4.5
ARF
4.4
AML/MDS
4.4
Mouse hepatitis
4.4
Papillomas
4.3
tumorigenesis
4.3
Medulloblastoma
4.3
hereditary fructose intolerance
4.3
GS2
4.3
anaplastic thyroid cancer
4.3
kidney hypertrophy
4.2
more...
Symptom
No toxic effect
5.6
ataxic gait
3.8
starvation
3.6
HSA
2.4
joint stiffness
1.9
decreased appetite
1.7
fasciculation
1.6
hyperoxia
1.6
collapse
1.2
memory loss
1.1
hepatomegaly
0.4
functional recovery
0.2
exhaustion
0.2
cerebellar ataxia
0.1
ataxia
-0.1
pelvic pain
-0.1
acute stress
-0.3
wheezing
-0.3
seizures
-0.7
diarrhea
-0.7
distraction
-1.3
thinning
-1.6
nausea
-1.6
fatigue
-1.8
hypothermia
-2.2
tremor
-2.3
weakness
-2.3
respiratory distress
-2.4
discomfort
-2.6
discomfort
-2.7
pain
-2.8
overweight
-2.8
headache
-2.9
analgesia
-2.9
abdominal pain
-3.0
vomiting
-3.1
anesthesia
-3.8
Drug
Olomoucine
10.4
Purvalanol
10.0
7-Hydroxystaurosporine
9.7
Flavopiridol
9.1
Ilmofosine
8.2
Alvocidib
8.1
Mevastatin
8.1
Adozelesin
7.1
Maduramicin
7.1
2-Methoxyestradiol
6.8
Trenbolone acetate
6.5
Rapamune
6.4
Mizoribine
6.3
Sevelamer hydrochloride
6.3
Zebularine
5.8
Marimastat
5.7
Velban
5.7
Vesnarinone
5.6
Compound 19
5.4
Fulvestrant
5.4
Vorinostat
5.4
Bosutinib
5.3
Casodex
5.3
Nexavar
5.2
Sevelamer
5.1
CA-074
5.1
Romidepsin
5.1
K-252a
5.1
Safflower
5.0
DMAP
4.9
Pertuzumab
4.9
MDM
4.8
Epigallocatechin
4.7
Arsenic trioxide
4.6
Lovastatin
4.5
Swainsonine
4.5
Estrogens
4.5
Bromelain
4.5
Troglitazone
4.4
Gatifloxacin
4.4
Bortezomib
4.4
Retinoic Acid
4.3
Lipidex
4.3
Cetrorelix
4.3
Lupron
4.2
Pravastatin
4.2
Cinacalcet
4.2
Glide
4.2
NOV
4.2
Herceptin
4.1
Spiegel
4.0
Emodin
4.0
Ginger
4.0
Miltefosine
4.0
Gefitinib
4.0
PFT
4.0
Compound 9
3.9
RAL
3.9
Taxol
3.8
Nebivolol
3.8
ICI
3.8
BLM
3.8
Areca
3.8
Activin
3.8
Emodin
3.7
CLS
3.7
MAP
3.7
Myricetin
3.6
Monensin
3.6
NVP
3.6
TAK
3.5
Isotretinoin
3.5
DEL
3.5
Artesunate
3.5
TAT
3.5
AraC
3.4
SPP
3.3
Tannic acid
3.3
SMP
3.3
Orlistat
3.3
more...
Enzyme
cdc2
11.9
CTD kinase
8.9
SMP-I
8.7
STK4
8.1
chondroitin 4-sulfotransferase
7.4
CLK1
7.4
STK3
7.1
polo-like kinase 1
6.7
AO1
6.7
STK2
6.4
nucleoside diphosphokinase
6.1
protein kinase
6.1
CTS2
6.1
poly(A)-specific ribonuclease
6.0
separase
5.8
GSK
5.8
phosphatidate phosphatase
5.8
STK
5.7
caspase-7
5.7
PARP
5.7
caspase-7
5.6
poly(A)-specific ribonuclease
5.6
type 1 protein phosphatase
5.5
splicing endonuclease
5.5
caspase-9
5.5
CYP8B1
5.4
phosphatidylinositol-4,5-bisphosphate 3-kinase
5.3
protein phosphatase 2A
5.2
20beta-hydroxysteroid dehydrogenase
5.2
galactose-1-phosphate uridylyltransferase
5.2
poly(A) polymerase
5.1
mu-calpain
5.1
eEF2 kinase
5.0
CTP synthase
5.0
MEK
5.0
caspase-8
5.0
factor C
4.9
stromelysin-3
4.9
caspase-3
4.9
succinyl-CoA synthetase
4.8
ribonucleotide reductase
4.7
ribonucleotide reductase
4.7
calcineurin
4.7
proteasome
4.6
calpain 3
4.6
peptidyl-prolyl cis-trans isomerase
4.6
MAP
4.6
mitogen-activated protein kinase
4.6
ubiquitin-protein ligase
4.6
dCMP deaminase
4.5
caspase-10
4.4
caspase-10
4.4
PDK1
4.4
sphingosine kinase
4.4
GD3 synthase
4.4
isopeptidase
4.3
histone demethylase
4.3
aspartoacylase
4.3
topoisomerase
4.3
valyl-tRNA synthetase
4.3
phosphatidylinositol 3-kinase
4.3
dUTPase
4.2
RNA polymerase
4.2
histone acetyltransferase
4.2
phosphocholine cytidylyltransferase
4.2
beta-1,4-galactosyltransferase
4.2
phosphoinositide 3-kinase
4.1
topoisomerase
4.1
pyridoxal kinase
4.1
MEKK1
4.0
AP lyase
4.0
sphingomyelin synthase
4.0
caspase-6
4.0
NCP
4.0
pantothenate kinase
4.0
spermidine/spermine N1-acetyltransferase
3.9
caspase-6
3.9
APC
3.9
N-acetylglucosaminyltransferase
3.9
protein kinase C
3.9
more...
Compound
Orbencarb
11.9
Withaperuvin B
10.9
AB 48
10.9
Longikaurin A
10.3
Spectinabilin
10.3
phenylmethanesulfonamide
10.3
3,5-dibromopyridine
9.7
Decylubiquinone
9.6
Valtrate
9.6
Quinalizarin
9.4
methyl dihydrogen phosphate
9.1
Undecylprodigiosin
8.9
Sinularin
8.9
Methylselenocysteine
8.8
Corydaline
8.6
Squamocin
8.4
Oxypeucedanin
8.4
Apigetrin
8.4
Tricetin
8.2
Pancratistatin
8.1
delta12,14-PGJ2
8.0
S152
8.0
AR 1
7.9
1'-Acetoxychavicol acetate
7.9
C2H4O2
7.8
Endothall
7.8
GBL
7.8
C2H5NO2
7.7
Ver A
7.7
Deoxyelephantopin
7.7
Dehydrocostus lactone
7.7
C2H4O2
7.7
Camphorquinone
7.4
Chelidonine
7.4
G 1
7.4
Sennoside A
7.4
N-methylvaline
7.3
Destruxin A
7.3
Indirubin
7.3
Echinacoside
7.3
Tuberin
7.3
Pristimerin
7.2
Pristimerin
7.2
Decursin
7.2
Pristimerin
7.2
Pristimerin
7.2
Octyl gallate
7.1
Ciclopirox olamine
7.1
Scutellarein
7.1
Hinokitiol
7.0
Cercosporin
6.9
Pactamycin
6.9
2-Methoxyestradiol
6.8
Ophiobolin A
6.8
Costunolide
6.7
Sclareol
6.6
Pheophorbide a
6.6
Deoxypodophyllotoxin
6.6
Combretum caffrum
6.6
Tetrahydropalmatine
6.6
Pheophorbide a
6.6
Mimosine
6.6
Mangostin
6.5
Amygdalin
6.5
Metanil yellow
6.5
Pinoresinol
6.5
Amygdalin
6.5
Mimosine
6.5
Microcephalin
6.4
Evodiamine
6.4
N-phenylbenzamide
6.4
Evodiamine
6.3
SC-58125
6.3
ML-236B
6.3
Nikkomycin Z
6.3
Oridonin
6.2
Lupeol
6.2
Phorbol-12,13-dibutyrate
6.2
Flavone acetic acid
6.2
Phenethyl isothiocyanate
6.1
more...