Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:2.7.11.22 (cdc2)
 8,319 document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
cyclin 2129
p21 1396
cyclin E 1254
Mol 1107
cdk2 1105
p27 998
p53 969
cyclin A 961
cyclin D1 949
cyclin-dependent kinase 855
Sep 570
cyclin B1 509
CDK2 391
Cyclin 368
cyclin D 342
p16 340
pRb 332
caspase-3 330
CDK4 322
p34 304
more...
Disease
cancer 1713
tumor 1209
retinoblastoma 712
breast cancer 424
tumorigenesis 302
carcinoma 246
tumor growth 196
carcinogenesis 181
hepatocellular carcinoma 175
MCF 173
leukemia 172
Alzheimer's disease 151
prostate cancer 131
melanoma 107
lung cancer 106
colon cancer 102
ATM 96
squamous cell carcinoma 94
tumor progression 85
lymphoma 82
more...
Symptom
starvation 81
collapse 17
seizures 13
pain 10
diarrhea 9
functional recovery 4
HSA 4
exhaustion 4
fatigue 4
ataxia 4
hyperoxia 4
ataxic gait 2
weakness 2
nausea 2
memory loss 2
headache 2
anesthesia 2
hepatomegaly 2
decreased appetite 1
abdominal pain 1
more...
Drug
lysine 61
MAP 54
ROS 44
caffeine 39
IL-2 38
Flavopiridol 30
ICI 20
Dermatol 19
Gel 15
Olomoucine 15
Estrogens 13
CSF 13
Taxol 12
Herceptin 10
IFN-gamma 9
DMAP 9
Arsenic trioxide 8
Lovastatin 8
Bortezomib 8
Monit 8
more...
Enzyme
cdc2 8319
protein kinase 1494
mitogen-activated protein kinase 607
ERK 338
caspase-3 270
protein kinase C 193
proteasome 188
PARP 179
RNA polymerase 172
MEK 149
calcineurin 115
focal adhesion kinase 106
GSK 100
caspase-9 88
glutathione S-transferase 74
luciferase 72
APC 65
phosphatidylinositol 3-kinase 56
caspase-8 56
DNA polymerase 55
more...
Compound
DNA 1987
Dec 629
threonine 431
serine 367
tyrosine 356
ATP 192
oxygen 163
alanine 147
calcium 127
MTT 110
MDA 104
MEK 102
phosphate 94
lysine 85
cAMP 76
glucose 73
proline 73
Clin 69
cysteine 67
retinoic acid 63
more...