Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:2.7.11.2 (PDK1)
 2,238 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
PDK3 13.8
actinin, alpha 2 13.8
CRHSP24 13.8
STK1 13.8
acyl-CoA synthetase short-chain family member 1 13.8
SRM160 13.8
alcohol dehydrogenase, iron containing, 1 13.8
aldose reductase-related protein 13.8
SGK494 13.8
Ankyrin repeat domain-containing protein 22 13.8
pyruvate dehydrogenase kinase 13.8
SYT16 13.8
PDK2 13.8
OXCT protein 13.8
PDK4 13.8
branched chain alpha-ketoacid dehydrogenase kinase 13.8
PDK1 13.8
PDK 13.6
stk2 13.2
PDK4 protein 13.0
PDP2 12.9
TBC1D30 12.8
epithelial protein lost in neoplasm beta 12.8
PCYT1B 12.8
phosphoinositide-3-kinase, catalytic, beta polypeptide 12.8
ATP1G1 12.8
CSRNP3 12.8
CORO2A 12.8
PDHK2 12.6
PDK1 protein 12.4
STK2 12.3
BRP44 12.2
PANK4 12.2
PLEKHG4B 12.2
stem cell tyrosine kinase 1 12.2
CRIK 12.0
mitochondrial fission regulator 1 11.8
NEDL2 11.8
BRP44L 11.8
tolloid-like protein 11.8
pyruvate dehydrogenase alpha subunit 11.5
Pak-2 11.5
NFKBIL2 11.5
VPP1 11.5
THBS1 protein 11.5
bpoz 11.5
ZNF367 11.5
PHLPPL 11.5
apoptosis facilitator 11.5
INPP4B protein 11.5
ZBTB2 11.3
SGK3 11.3
PLXDC2 11.2
OSBPL3 11.2
GNGT2 11.2
C1QTNF3 11.2
FASTK 11.2
hMAP126 11.2
CHPPR 11.2
FRMD8 11.2
CSNK1G1 11.2
DAPL1 11.2
RPS6KB2 11.1
MYO1B 11.1
cytokine-independent survival kinase 11.1
GRAP 11.1
PRK2 11.0
PDPK1 11.0
ACN9 11.0
TMEM129 11.0
SYT5 11.0
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 11.0
HIST1H2AC 11.0
ACSS1 11.0
ZPR9 11.0
BTNL9 11.0
KIAA1324 11.0
COX4I2 10.9
PFKFB4 10.9
3-phosphoinositide-dependent protein kinase 1 10.8
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Disease
Hyper IgM syndrome 10.1
CEBPG 9.9
SHORT syndrome 9.8
Familial dilated cardiomyopathy 9.3
PDH deficiency 8.9
Neovascular age-related macular degeneration 8.8
Endometrioid carcinoma 8.6
Parvovirus infection 8.4
Late pregnancy 8.3
AUTS2 8.0
Calcium deficiency 7.9
PDP 7.6
PDC 7.6
ARTS 7.5
Transient cerebral ischemia 7.3
adult brain tumor 7.3
FED 7.1
recurrent NSCLC 7.1
hereditary sensory neuropathy 7.0
HRD 6.9
recurrent endometrial cancer 6.9
Peritoneum 6.7
Peritoneum 6.7
DMM 6.7
cancer angiogenesis 6.7
RP11 6.6
cancer regression 6.6
Pleura 6.6
Ileum 6.6
Pleura 6.5
PSN 6.5
Dengue hemorrhagic fever 6.4
Diabetic peripheral neuropathy 6.4
hemiparkinsonism 6.3
Postoperative cognitive dysfunction 6.3
SCD 6.2
Malignant glioma 6.0
MSF 6.0
Autosomal recessive polycystic kidney disease 5.8
PARK2 5.8
CAE 5.8
hypoglycemic coma 5.7
CMT1A 5.7
NCR 5.6
HTS 5.5
lactic acidosis 5.5
CYLD 5.5
Estrogen deficiency 5.4
OPA1 5.4
LIN 5.4
metastatic ovarian cancer 5.3
large cell carcinomas 5.3
Liver regeneration 5.3
FAS 5.1
CLS 5.1
Vesicular stomatitis 5.1
RBS 5.1
Cholangiocarcinoma 5.0
CEP 5.0
AGS 5.0
Pulmonary arterial hypertension 4.9
Glioblastoma 4.9
Cholangiocarcinoma 4.9
Peutz-Jeghers syndrome 4.9
Leigh syndrome 4.9
tuberous sclerosis 4.8
Diaphragm 4.8
proliferative vitreoretinopathy 4.7
TEC 4.7
heroin addiction 4.7
diabetic cardiomyopathy 4.7
eastern equine encephalitis 4.7
Neuroblastoma 4.7
Neuroblastoma 4.7
ovarian dysfunction 4.7
vascular obstruction 4.6
Charcot-Marie-Tooth disease 4.6
FBS 4.6
polycythemia 4.6
intestinal cancer 4.5
more...
Symptom
starvation 5.3
eye pain 5.2
neurological disability 3.9
cachexia 3.7
decreased appetite 3.6
skin damage 3.2
exhaustion 3.1
dry eye 2.4
sore throat 2.4
hunger 2.3
HSA 2.2
acidity 2.2
polyuria 2.2
ophthalmoplegia 2.1
memory loss 2.0
pelvic pain 1.8
acute stress 1.6
numbness 1.5
hyperoxia 1.4
hypothermia 1.3
flushing 1.2
myalgia 1.1
anorexia 1.0
weakness 0.9
ataxia 0.8
fatigue 0.7
overweight 0.7
tremor 0.6
Ill 0.3
functional recovery 0.1
collapse -0.0
seizures -0.5
pain -1.6
anesthesia -2.0
headache -2.0
Drug
Diisopropylamine dichloroacetate 12.8
Sodium dichloroacetate 10.8
Hymenialdisine 10.5
Japanese encephalitis vaccine 7.7
Red ginseng 6.9
Etodolac 6.8
RAL 6.8
Triclosan 6.3
Flavopiridol 6.1
NOV 6.1
Ranolazine 5.8
Ranolazine 5.8
Zmax 5.8
Troglitazone 5.7
Rosiglitazone 5.7
CER 5.7
Exenatide 5.5
Cilostazol 5.1
AHF 4.9
KGF 4.9
NVP 4.9
ROS 4.6
AMC 4.6
NADH 4.5
Glycyrrhiza 4.3
Gleevec 4.3
OTC 4.3
Erlotinib 4.2
Amiloride 4.2
Fragment 4.2
Simvastatin 4.1
citric acid 4.0
Amiloride 4.0
Alanine 3.9
Itraconazole 3.9
TAK 3.8
Ketoconazole 3.8
OTC 3.7
Etoposide 3.6
Gefitinib 3.6
Azithromycin 3.5
Imatinib 3.5
Ouabain 3.5
Bortezomib 3.3
Sorafenib 3.2
Heme 3.2
GEO 3.2
Ginseng 3.1
Retinoic acid 3.1
Parkin 2.9
Parkin 2.9
Fructose 2.9
Portal 2.8
uPA 2.8
vitamin E 2.7
MAP 2.7
Herceptin 2.6
Glycerol 2.6
TMS 2.6
Nitric Oxide 2.5
Forskolin 2.4
ICI 2.4
ALA 2.3
Rituximab 2.3
lysine 2.2
ADM 2.2
Taxol 2.2
MRC 2.1
Kenyan 2.0
PCP 1.9
Glucagon 1.9
niacin 1.9
Asn 1.9
Angiotensin II 1.5
CaCl2 1.2
CaCl2 1.2
CaCl2 1.1
caffeine 1.0
Leaf 1.0
ascorbate 0.9
more...
Enzyme
PDK1 13.8
pyruvate dehydrogenase phosphatase 12.4
BCKDH 10.9
STK2 10.9
pyruvate dehydrogenase 10.4
pyruvate dehydrogenase 10.4
pyruvate dehydrogenase 10.2
PDH 10.2
lipoate acetyltransferase 9.7
HK3 9.0
STK3 9.0
HK2 8.8
inositol polyphosphate 4-phosphatase 8.6
serum carnosinase 8.0
glycogenin 7.6
malonyl-CoA decarboxylase 7.6
myo-inositol oxygenase 7.5
protein L-isoaspartyl methyltransferase 7.5
CYP8B1 7.3
branched-chain alpha-keto acid dehydrogenase 7.2
phosphoinositide 3-kinase 7.1
2,4-dienoyl-CoA reductase 7.1
6-phosphofructo-2-kinase 7.0
rhomboid protease 7.0
inositol phosphatase 7.0
TOR 6.9
carnosinase 6.9
PHT 6.8
myo-inositol-1-phosphate synthase 6.8
phosphatidylinositol 3-kinase 6.8
CPT 6.7
STK 6.6
AMP-activated kinase 6.5
oxoglutarate dehydrogenase 6.5
ubiquinol-cytochrome c oxidoreductase 6.4
3'-phosphatase 6.4
AMPK 6.3
prolyl hydroxylase 6.3
GSK 6.3
hormone-sensitive lipase 6.2
succinyl-CoA synthetase 6.1
pyruvate carboxylase 6.0
AMP-activated protein kinase 6.0
3-hydroxyacyl-CoA dehydrogenase 6.0
glutathione synthetase 6.0
STK11 5.9
eEF2 kinase 5.9
acyl-CoA dehydrogenase 5.9
phosphomannomutase 5.9
acetyl-CoA carboxylase 5.9
CPT 5.9
peptide deformylase 5.9
fatty acid elongase 5.8
phosphofructokinase 5.8
phosphoribulokinase 5.8
pyruvate kinase 5.8
acyl-CoA dehydrogenase 5.8
TACE 5.7
CPT 5.7
AMPK 5.7
LPL 5.7
hexokinase 5.7
citrate lyase 5.7
PKG 5.7
pyruvate decarboxylase 5.7
MEK 5.6
phosphoenolpyruvate carboxykinase 5.6
focal adhesion kinase 5.6
protein kinase 5.5
glutaminase 5.5
alpha-ketoglutarate dehydrogenase 5.5
ACE 5.5
Omi/HtrA2 5.4
farnesyltransferase 5.4
protein kinase C 5.3
CEP 5.2
phosphoenolpyruvate carboxykinase 5.2
phosphoenolpyruvate carboxykinase 5.2
polo-like kinase 1 5.2
fructose 1,6-bisphosphatase 5.2
more...
Compound
C9H10O3 11.8
GRP-1 10.6
Pachypodol 10.5
Dichloroacetate 10.4
Pachymic acid 10.0
Palmitoyl-L-carnitine 10.0
2-oxopropanamide 9.9
TCPA 9.9
S152 9.9
PDH 9.6
Deoxyelephantopin 9.6
2-methylpropanamide 9.5
difluoroacetic acid 9.3
Hymenialdisine 9.2
Hordenine 9.0
2,2-dichloroacetamide 8.9
Morusin 8.9
Phytosphingosine 8.8
WY-14,643 8.7
1H-pyrazolo[3,4-d]pyrimidine 8.4
Dibenzoylmethane 8.4
PDP 8.1
Anacardic acid 8.0
DX-52-1 7.8
Fusaric acid 7.7
Fusaric acid 7.7
Fusaric acid 7.7
acetyl-CoA 7.6
Asiaticoside 7.5
Succinyl-CoA 7.5
DCA 7.4
DCA 7.4
Pyruvate 7.4
Monocrotaline 7.3
LY 294002 7.2
Diacetoxyscirpenol 7.2
Acriflavine 7.2
Betulinic acid 7.2
dihydrolipoamide 7.1
NIX 7.0
bromoacetic acid 7.0
Phenethyl isothiocyanate 7.0
DBI 6.9
Betulin 6.9
Rottlerin 6.9
Kojic acid 6.9
PHT 6.8
Rottlerin 6.8
Rottlerin 6.8
Dihydromyricetin 6.8
2-Deoxy-D-glucose 6.6
TSC 6.5
Wortmannin 6.4
DEN 6.4
Isoliquiritigenin 6.4
Carnosine 6.4
AA861 6.3
KIV 6.3
Sesamin 6.3
octanoyl-CoA 6.3
TPCK 6.3
malonyl-CoA 6.2
Phosphatidylinositol 6.2
DGE 6.2
AGE 6.2
DGE 6.1
DGE 6.1
TPP 6.1
8-quinolinol 6.1
cis-vaccenic acid 6.0
Glyoxylate 6.0
DOCA 6.0
Salinomycin 6.0
Plumbagin 6.0
heptadecanoic acid 5.9
(-)-Epigallocatechin 5.9
Celecoxib 5.9
Baicalein 5.9
Caffeic acid phenethyl ester 5.9
CPT 5.9
more...