Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:2.7.11.2 (PDK1)
 2,238 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
PDK1 980
pyruvate dehydrogenase kinase 637
PDK 528
pyruvate dehydrogenase 348
insulin 327
PDK4 300
PI3K 256
AKT 223
Mol 220
mTOR 210
ATP 208
pyruvate dehydrogenase complex 201
Sep 143
PDK2 129
PKB 105
phosphatase 101
PTEN 95
protein kinase B 87
PDH 86
phosphatidylinositol 3-kinase 85
PKC 72
ERK 66
threonine 64
MAPK 64
ERK1 59
phosphoinositide 3-kinase 58
S6K1 55
p53 49
glucose transporter 48
peroxisome proliferator-activated receptor 48
PGC 47
Bcl-2 47
ADP 46
caspase-3 45
Pyruvate dehydrogenase 42
phosphorylating 41
MEK 40
PDK3 40
insulin receptor 38
p38 38
NADH 37
SGK1 36
IRS-1 35
AMPK 35
lactate dehydrogenase 34
PDK4 protein 33
cyclin D1 33
ROS 33
pleckstrin 33
PI3 32
GSK 32
vascular endothelial growth factor 31
JNK 30
PKA 30
lactate dehydrogenase A 29
PH domain 28
TCA 28
rhabdomyosarcoma 28
tyrosine kinase 27
AMP-activated protein kinase 27
LDHA 26
p70 26
GLUT1 26
p21 26
GLUT4 26
catenin 25
VEGF 24
NAD 24
AMP 23
MEK1 23
UCP3 22
serine/threonine kinase 22
cytokine 22
SGK 22
peroxisome proliferator-activated receptor gamma 22
p27 21
EGF 21
PPAR 21
insulin-like growth factor 21
p85 21
IGF-1 21
pyruvate dehydrogenase kinase 4 21
ribosomal S6 kinase 20
HIF-1 20
PKM2 19
pyruvate kinase 19
NMR 19
collagen 19
GSK3 19
STK1 19
hexokinase 19
CD36 18
4E-BP1 18
EGFR 18
AKT1 17
lipopolysaccharide 17
epidermal growth factor 17
PIK3CA 17
c-Myc 17
IL-6 17
HK2 17
CREB 16
ribosomal protein S6 16
PI3-kinase 16
epidermal growth factor receptor 16
LC3 16
RSK 16
SGK3 16
ATPase 15
carnitine palmitoyltransferase 15
PIP3 15
TSC2 15
histone 15
cytochrome c 15
caspase-9 14
ubiquitin 14
receptor tyrosine kinase 14
protein phosphatase 14
p70 S6 kinase 14
phosphofructokinase 14
CPT1 14
PtdIns 13
PIF 13
PARP 13
UTR 13
endoplasmic reticulum 13
TNF 13
PP2A 13
STAT3 13
superoxide dismutase 13
ENaC 13
extracellular signal-regulated kinase 13
glycogen synthase 13
CPT 13
pyruvate kinase M2 13
TOR 12
SIRT1 12
p65 12
beta-catenin 12
TORC2 12
BAD 12
3-phosphoinositide-dependent protein kinase 1 12
RhoA 12
IRS-2 12
mitogen-activated protein 12
HIF-1alpha 12
RAF 12
acetyl-CoA carboxylase 12
hexokinase 2 12
p90 11
fibronectin 11
PDC 11
Rho 11
insulin receptor substrate 11
cyclin 11
forkhead transcription factor 11
MYC 11
PDPK1 11
HEK 11
catalase 11
citrate synthase 11
BRAF 11
histone deacetylase 11
COX-2 11
hormone-sensitive lipase 11
serine/threonine protein kinase 11
HER2 11
hexokinase II 10
PIP 10
cAMP-dependent protein kinase 10
glucagon 10
DAF 10
FAS 10
leptin 10
estrogen receptor 10
c-Jun 10
proliferating cell nuclear antigen 10
PDP2 10
caspase-8 10
polypeptide 10
phosphatase and tensin homolog 10
phosphoenolpyruvate carboxykinase 10
angiotensin II 10
E-cadherin 10
Nedd4-2 10
tensin 10
NAD+ 9
insulin-like growth factor 1 9
RSK1 9
p38MAPK 9
PKG 9
proline-rich 9
CK2 9
ras 9
tumor necrosis factor 9
ACC 9
adiponectin 9
BNIP3 9
ANGPTL4 9
Hsp90 9
thyroid hormone 9
Aurora-A 9
PDK1 protein 9
PAK1 9
SOD 9
atrogin-1 9
IRS 9
epididymal 9
p38 mitogen-activated protein kinase 9
proteasome 9
UCP2 9
FAK 9
CDK4 9
GST 9
c-myc 8
CCK 8
cyclin A 8
4EBP1 8
LDH 8
GSH 8
OXPHOS 8
NHE3 8
integrin-linked kinase 8
FOXO3 8
TFAM 8
carnitine palmitoyltransferase I 8
glutathione S-transferase 8
PC-3 8
PRK2 8
cage 8
p62 8
AP-1 8
VEGFR2 8
vimentin 8
p44 8
glycoprotein 8
urocortin 8
cytochrome 8
MAP kinase 8
focal adhesion kinase 8
ERK2 8
CDK2 8
cytochrome c oxidase 8
14-3-3 8
interacting protein 8
endothelial nitric oxide synthase 8
IKK 8
PEPCK 8
protein X 8
SGLT1 7
cardiac muscle 7
PPARGC1A 7
NS5 7
IGF-I 7
glucocorticoid receptor 7
glucokinase 7
MHC 7
calcineurin 7
p110 7
EGF receptor 7
E3 ubiquitin ligase 7
BAX 7
ROMK 7
calmodulin 7
thrombin 7
insulin-like growth factor-I 7
osteogenic 7
c-Src 7
ubiquitin ligase 7
IGF1R 7
phosphoprotein 7
muscle protein 7
CPT I 7
pyruvate carboxylase 7
Met 7
chemokine 7
CD34 7
hemoglobin 7
KCNQ1 7
eNOS 7
PPAR gamma 7
TORC1 7
cyclin E 7
osteosarcoma 7
sirtuin 1 7
nerve growth factor 6
ACS 6
uncoupling protein 1 6
MRI 6
CPT1A 6
AKT2 6
Nrf2 6
TSC1 6
YAP 6
Fibroblast growth factor 21 6
MyoD 6
glutaminase 6
FABP4 6
tumour suppressor 6
SCD 6
adipose triglyceride lipase 6
SCD1 6
KCNE1 6
STK2 6
Gen 6
STAT5 6
lipoprotein lipase 6
PDHA1 6
ribosomal protein 6
PKD1 6
inducible nitric oxide synthase 6
fatty acid synthase 6
SIN1 6
GTPase 6
COX 6
IFN 6
SDS 6
isocitrate dehydrogenase 6
LPS 6
FKHRL1 6
transporter 1 6
SHP-2 6
androgen receptor 6
nuclear receptor 6
adaptor protein 6
myosin 6
glucose-6-phosphatase 6
glucose-6-phosphate dehydrogenase 6
hinge 6
albumin 6
PKC zeta 6
RSK2 6
PLC 6
p42 6
LDH-A 6
PPARD 6
carbonic anhydrase IX 6
dimeric 6
GTP 6
BOD 6
X-linked 6
PDB 6
cyclooxygenase 6
cyclooxygenase-2 5
fused 5
ULK1 5
PFKFB3 5
GLUT2 5
phosphodiesterase 5
PFKFB4 5
MAP 5
PGC-1 5
APC 5
c-kit 5
MMP-9 5
PDHC 5
phospholipase D 5
glyceraldehyde 3-phosphate dehydrogenase 5
HIF1 5
keratinocyte growth factor 5
brain-derived neurotrophic factor 5
thymidine kinase 5
IL6 5
Kv1.5 5
platelet-derived growth factor 5
MSTN 5
CFTR 5
creatine kinase 5
SIRT3 5
CXCR4 5
MuRF1 5
IRS2 5
inhibitor 2 5
Fas 5
LPL 5
HKII 5
PI-3 kinase 5
raptor 5
GluR6 5
G6Pase 5
XIAP 5
PKN 5
LKB1 5
CXCL12 5
COXIV 5
membrane-bound 5
CDK1 5
cyclin B1 5
PPAR-alpha 5
COX4I2 5
NS1 5
monocarboxylate transporter 5
AGS 5
thymus 5
dihydrolipoamide acetyltransferase 5
annexin V 5
FGF 5
HDL 5
growth hormone 5
p16 5
ILK 5
heme oxygenase-1 5
long chain 5
NAC 5
NDRG1 5
SRC 5
fatty acid translocase 5
sirtuin 5
PIK3R1 5
extracellular signal-regulated kinase 1 5
alpha-chain 5
Raf-1 5
eIF4E 5
N-cadherin 5
PC3 5
NRF2 5
AGE 5
STAT 5
KRAS 5
IGF1 5
erythroid 5
Pyruvate kinase M2 5
TLR4 5
CHK1 5
INSR 4
prolactin 4
E2F1 4
PFK-2 4
TOF 4
HIF1A 4
MMP-2 4
matrix protein 4
DNA methyltransferase 4
RICTOR 4
TRAIL 4
PDGF 4
SGK2 4
mast cell 4
lipoamide 4
myostatin 4
ANOVA 4
SLC2A4 4
carnitine palmitoyltransferase 1 4
Ki-67 4
MCT-1 4
G protein-coupled receptor 4
Kv1.3 4
Insulin receptor 4
BCL2 4
cytochrome P450 4
FRAP 4
Yes 4
Na(+)/K(+)-ATPase 4
MRS 4
c-fos 4
PHD2 4
ZFP 4
mer 4
Rheb 4
PCK1 4
heat shock protein 4
PI3Kgamma 4
P21 4
PEPCK-C 4
Ang II 4
pVHL 4
GDC 4
TSC 4
FASN 4
PDHK2 4
PRK1 4
IL-10 4
housekeeping 4
TRPV5 4
cyclic AMP phosphodiesterase 4
CEBPB 4
plasminogen activator inhibitor-1 4
ESR1 4
KDR 4
SREBP-1 4
Mcl-1 4
phospholipase 4
REDD1 4
phosphoglycerate kinase 1 4
CO2 4
Phosphoinositide 3-kinase 4
PKC-alpha 4
atrial natriuretic peptide 4
NDR 4
5-lipoxygenase 4
glucose transporter 3 4
CPTI 4
MK2 4
TRPV4 4
ABCA1 4
JNK1 4
Peroxisome proliferator-activated receptor 4
Men 4
PP2 4
casein 4
MCT1 4
BCR 4
tumor necrosis factor alpha 4
ACL 4
CD44 4
acetyltransferase 4
mitochondrial transcription factor A 4
MAPK1 4
SAR 4
FAT 4
NHE1 4
gut 4
glucose transporter 4 4
RPMI 4
monocarboxylate transporter 1 4
ATM 4
MuRF 4
ROCK1 4
TBK1 4
SOD2 4
SCN5A 4
transcriptional coactivator 4
HGF 4
receptor kinase 4
adipokine 4
MSK1 4
glutamine synthetase 4
Gab1 4
ACAT1 4
p47 4
IGFBP1 4
GLUT-4 4
NRF-1 4
alkaline phosphatase 3
AF10 3
like kinase 3
glycogen synthase kinase 3 3
MnSOD 3
adapter protein 3
spermatozoa 3
PD-1 3
CTGF 3
AFX 3
HIF-1 alpha 3
NMDA receptor 3
O-GlcNAc transferase 3
CA IX 3
inositol phosphatase 3
STIM1 3
LCE 3
scratch 3
myosin heavy chain 3
glial fibrillary acidic protein 3
Smad3 3
prion 3
transcriptional factor 3
FGF receptor 3
PERK 3
ERR 3
ACOX1 3
EMT 3
ACSS1 3
Cyclin D1 3
alanyl 3
Citrate synthase 3
CCND1 3
GBL 3
GRP78 3
FLIP 3
A431 3
VIII 3
atrial natriuretic factor 3
vasopressin 3
TGF-beta 3
glycoprotein VI 3
NADPH 3
ACC1 3
HDAC 3
MRF4 3
PARKIN 3
insulin receptor substrate-2 3
TXNIP 3
ENO2 3
EAAC1 3
TIEG1 3
stearoyl-CoA desaturase 3
RPS6KB2 3
STAT1 3
transmembrane protein 3
lactate dehydrogenase-A 3
protein serine/threonine kinase 3
GBS 3
Gallus gallus 3
all-trans 3
vascular endothelial growth factor A 3
HER3 3
Oct4 3
MAST 3
tyrosine phosphatase 3
vascular endothelial growth factor receptor 2 3
protein kinase D 3
myosin light chain 3
homeobox 3
LATS 3
CBP 3
orexin 3
TAK1 3
NOX4 3
SOX2 3
metadherin 3
MYCN 3
EGR1 3
non-catalytic 3
Protein kinase 3
IL-8 3
malonyl-CoA decarboxylase 3
ezrin 3
PINK1 3
adhesion molecule 3
Raptor 3
malate dehydrogenase 3
PDGFR 3
VPS34 3
HSP70 3
FBS 3
glutathione synthetase 3
MKK6 3
natriuretic peptide 3
PUMA 3
alanine aminotransferase 3
2-oxoglutarate dehydrogenase 3
cyclin-dependent kinase inhibitor 3
RPS6KB1 3
Tumor necrosis factor 3
Pol 3
AS1 3
NRF1 3
MAP2K1 3
GAPDH 3
chymotrypsin 3
more...
Disease
cancer 490
tumor 267
diabetes 127
breast cancer 75
obesity 70
tumor growth 68
tumorigenesis 67
type 2 diabetes 47
carcinoma 42
ischemia 41
hepatocellular carcinoma 39
tumor progression 37
colorectal cancer 35
lung cancer 33
heart failure 31
prostate cancer 30
hyperglycemia 28
glioblastoma 28
colon cancer 25
carcinogenesis 25
adenocarcinoma 24
glioma 23
hypertension 23
non-small cell lung cancer 22
leukemia 22
gastric cancer 21
sepsis 20
sepsis 20
MCF 19
stroke 19
Alzheimer's disease 19
pancreatic cancer 17
dengue 17
acute myeloid leukemia 15
neuroblastoma 15
metastases 15
ovarian cancer 14
squamous cell carcinoma 13
lactic acidosis 13
hyperinsulinemia 13
metabolic syndrome 12
myocardial infarction 11
tuberous sclerosis 11
melanoma 11
PDC 11
glucose intolerance 11
depression 11
lymphoma 11
hyperthyroidism 11
cardiovascular disease 11
cold 11
cervical cancer 10
FAS 10
glioblastoma multiforme 10
Parkinson's disease 9
PDP 9
brain tumor 8
cerebral ischemia 8
atherosclerosis 8
plaque 8
Blocking 8
fatty liver 8
renal cell carcinoma 8
GSH 8
sickle cell disease 7
vascular disease 7
peripheral neuropathy 7
liver cancer 7
lung carcinoma 7
aggressiveness 7
Hippel 7
hypoglycemia 7
amyotrophic lateral sclerosis 7
osteosarcoma 7
hyperlipidemia 7
ATM 6
dyslipidemia 6
neuropathy 6
myocardial ischemia 6
ventricular hypertrophy 6
retinoblastoma 6
SDS 6
SCD 6
dilated cardiomyopathy 6
liver cancer 6
Glioblastoma 6
blindness 5
Charcot-Marie-Tooth disease 5
polycystic kidney 5
B-cell lymphoma 5
tumor angiogenesis 5
hypercholesterolemia 5
mammary tumor 5
myopathy 5
APC 5
cognitive impairment 5
solid tumor 5
diabetic nephropathy 5
pulmonary hypertension 5
bladder cancer 5
AGS 5
virus infection 5
endometrial cancer 4
multiple myeloma 4
pertussis 4
autoimmune disease 4
NS3 4
SAR 4
Neuroblastoma 4
Huntington's disease 4
rheumatoid arthritis 4
MRS 4
cardiomyopathy 4
malnutrition 4
epithelial ovarian cancer 4
right heart failure 4
epilepsy 4
diabetic retinopathy 4
Evans 4
Neuroblastoma 4
anemia 4
HGF 4
heart disease 3
congestive heart failure 3
AS1 3
worms 3
chronic lymphocytic leukemia 3
oral cancer 3
brain cancer 3
chronic myeloid leukemia 3
leukemogenesis 3
hematologic malignancies 3
PDH deficiency 3
hepatitis C 3
Pineal 3
colitis 3
ulcerative colitis 3
dementia 3
SEM 3
renal failure 3
NF2 3
infectious diseases 3
Japanese encephalitis 3
herpes simplex 3
WT1 3
head and neck cancer 3
Leigh syndrome 3
RP11 3
Hepatocellular carcinoma 3
diabetic cardiomyopathy 3
Melanoma 3
ABL 3
thyroid cancer 3
abortion 3
renal disease 3
EMT 3
Pulmonary arterial hypertension 3
viremia 3
adenoma 3
renal cancer 3
PDB 3
FBS 3
peptic ulcer 3
osteoporosis 3
polycythemia 3
type 1 diabetes 3
infertility 3
addiction 3
SCID 3
meningioma 3
immunodeficiency 3
HTS 3
asthma 3
influenza 3
OPA1 2
Graves' disease 2
chronic renal failure 2
papillary thyroid cancer 2
Cholangiocarcinoma 2
proteinuria 2
periodontitis 2
gastrointestinal cancer 2
multiple sclerosis 2
NCR 2
fibrosarcoma 2
yellow fever 2
Neovascular age-related macular degeneration 2
muscular atrophy 2
Mycobacterium 2
Peutz-Jeghers syndrome 2
Tumour necrosis 2
chronic pain 2
non-Hodgkin's lymphoma 2
glomerulosclerosis 2
metastatic breast cancer 2
PIN 2
DM1 2
endometriosis 2
pheochromocytoma 2
Friedreich's ataxia 2
cleft palate 2
SHORT syndrome 2
hepatitis 2
tumor initiation 2
primary pulmonary hypertension 2
esophageal cancer 2
polyposis 2
mitochondrial disease 2
Age-related macular degeneration 2
sarcoma 2
retinopathy 2
Osteosarcoma 2
intraocular pressure 2
LIN 2
Still 2
fits 2
NOD 2
coronary artery disease 2
Osteosarcoma 2
coronary occlusion 2
HIV 2
proliferative vitreoretinopathy 2
uterus 2
laryngeal cancer 2
TAM 2
Cryptococcus neoformans 2
rectal cancer 2
skin cancer 2
laryngeal cancer 2
hypernatremia 2
AIDS 2
vaccinia 2
dehydration 2
esophageal cancer 2
Cholangiocarcinoma 2
glaucoma 2
CEP 2
CAP 2
dermatitis 2
cirrhosis 2
cataract 2
PARK2 2
polycystic ovary syndrome 2
SARS 2
diabetic neuropathy 2
aggression 2
Infection 2
male infertility 2
chronic lymphocytic leukemia 2
TEM 2
West 2
inflammatory bowel disease 2
Duchenne muscular dystrophy 2
metabolic disorder 2
TEM 2
tuberculosis 2
cerebral infarction 1
vitamin D deficiency 1
bowel obstruction 1
Pleura 1
lung disease 1
transient ischemic attack 1
LDLR 1
gout 1
PSN 1
Creutzfeldt-Jakob disease 1
astrocytoma 1
Esophageal squamous cell carcinoma 1
HRD 1
hemiparkinsonism 1
CMT1A 1
chronic obstructive pulmonary disease 1
WSN 1
THC 1
von Willebrand disease 1
FED 1
CEBPG 1
cervicitis 1
infectious endocarditis 1
anal cancer 1
bone disease 1
MSF 1
renal insufficiency 1
cancer regression 1
lupus 1
hallucinations 1
systemic lupus erythematosus 1
protein deficiency 1
aortic stenosis 1
metastatic ovarian cancer 1
hamartoma 1
TEC 1
CHS 1
ovarian dysfunction 1
brain atrophy 1
parvovirus 1
acute tubular necrosis 1
synovitis 1
ureter 1
middle ear 1
MLC 1
acute lymphoblastic leukemia 1
Epstein 1
peritonitis 1
second cancer 1
pancytopenia 1
lymphadenopathy 1
Diaphragm 1
ventricular septal defect 1
cancer angiogenesis 1
cholestasis 1
cholesteatoma 1
familial cancer 1
Mycoplasma 1
fungal infection 1
myelodysplastic syndrome 1
choriocarcinoma 1
metastatic melanoma 1
pulmonary edema 1
emphysema 1
pulmonary fibrosis 1
Liver regeneration 1
Estrogen deficiency 1
adult brain tumor 1
NHL 1
myoma 1
uveal melanoma 1
pulmonary insufficiency 1
anaphylaxis 1
Parvovirus infection 1
SMS 1
bronchitis 1
pulmonic stenosis 1
Hypertrophic 1
myxedema 1
azoospermia 1
macular degeneration 1
Dengue hemorrhagic fever 1
HSP 1
PLS 1
acute myocardial infarction 1
hemorrhagic fever 1
Wells 1
dysplasia 1
angiomyolipoma 1
Burkitt's lymphoma 1
NPS 1
hereditary sensory neuropathy 1
DSS 1
mastocytoma 1
malaria 1
Recruitment 1
adenocarcinoma of the pancreas 1
hepatitis B 1
syndrome X 1
Esophageal 1
Wilson's disease 1
genetic disorder 1
ketosis 1
ADH 1
enteritis 1
lipid disorder 1
lung metastases 1
T-cell acute lymphoblastic leukemia 1
Postoperative cognitive dysfunction 1
oropharyngeal cancer 1
AIN 1
suicide 1
growth hormone deficiency 1
Cannabis 1
heroin addiction 1
prediabetes 1
nonmelanoma skin cancer 1
lipoatrophy 1
liver fibrosis 1
endometrial adenocarcinoma 1
urethra 1
intestinal cancer 1
atrophic gastritis 1
biliary tract cancer 1
Late pregnancy 1
iron deficiency 1
retinitis pigmentosa 1
gastroenteritis 1
retinopathy of prematurity 1
metachromatic leukodystrophy 1
HBB 1
vascular obstruction 1
paroxysmal nocturnal hemoglobinuria 1
CAE 1
embryonal rhabdomyosarcoma 1
Marek's disease 1
recurrent NSCLC 1
Chronic kidney disease (CKD) 1
NPC 1
rhabdomyosarcoma 1
idiopathic dilated cardiomyopathy 1
mastitis 1
arthritis 1
Colon cancer 1
acoustic neuroma 1
neuromuscular disorder 1
CYLD 1
cowpox 1
mental illness 1
bone cancer 1
Autosomal recessive polycystic kidney disease 1
Familial dilated cardiomyopathy 1
encephalomyelitis 1
NLS 1
craniosynostosis 1
essential hypertension 1
HCC 1
Hyper IgM syndrome 1
DMM 1
salmonellosis 1
acute myocarditis 1
hydronephrosis 1
periosteum 1
microalbuminuria 1
RBS 1
clear cell carcinoma 1
acute leukemia 1
metabolic alkalosis 1
anxiety disorders 1
inflammatory breast cancer 1
pneumonia 1
cystic fibrosis 1
wasting 1
limb-girdle muscular dystrophy 1
lipodystrophy 1
hyperlipoproteinemia 1
cytomegalovirus 1
Worms 1
Ileum 1
Calcium deficiency 1
ARTS 1
Endometrioid carcinoma 1
idiopathic pulmonary fibrosis 1
ALD 1
DSS 1
ischemic optic neuropathy 1
lymphangioleiomyomatosis 1
Malignant glioma 1
PCP 1
schizophrenia 1
hyperphagia 1
recurrent endometrial cancer 1
GAD 1
NAME 1
malignant mesothelioma 1
HBB 1
MRSA 1
HBB 1
scotoma 1
Peritoneum 1
intracranial tumors 1
Vesicular stomatitis 1
Ovarian Cancer 1
large cell carcinomas 1
Rhabdomyosarcoma 1
pneumothorax 1
spongiform encephalopathy 1
trichotillomania 1
invasive cancer 1
lupus 1
primary tumor 1
IBM 1
anal cancer 1
brain dysfunction 1
DES 1
hypoglycemic coma 1
DDP 1
thalassemia 1
mimicry 1
hypopituitarism 1
osteoarthritis 1
gallbladder cancer 1
Adhesion 1
hypothyroidism 1
AAA 1
human papilloma virus 1
human papilloma virus 1
Diabetic peripheral neuropathy 1
Transient cerebral ischemia 1
osteoma 1
COL2A1 1
MTS 1
acute renal failure 1
endocarditis 1
adenocarcinoma of the lung 1
obstructive sleep apnea 1
STD 1
Autism spectrum disorder 1
ventricular fibrillation 1
alcoholic fatty liver 1
glycogen storage disease 1
AMD 1
primary myelofibrosis 1
ganglioglioma 1
neoplastic transformation 1
silicosis 1
mantle cell lymphoma 1
chronic liver disease 1
abdominal aortic aneurysm 1
AUTS2 1
bronchitis 1
CEM 1
abdominal obesity 1
hereditary spherocytosis 1
preeclampsia 1
coagulopathy 1
Leukemia 1
Plaque 1
INS 1
laryngeal squamous cell carcinoma 1
eastern equine encephalitis 1
liver metastases 1
mesothelioma 1
Peritoneum 1
Esophagus 1
alkalosis 1
PIN 1
sleep apnea 1
Esophagus 1
Pleura 1
insulinoma 1
CLS 1
pH increased 1
WSN 1
Symptom
starvation 70
exhaustion 8
fatigue 6
pain 6
weakness 5
acidity 5
cachexia 5
seizures 4
hypothermia 3
overweight 3
hunger 2
ataxia 2
anesthesia 2
tremor 2
collapse 2
anorexia 2
eye pain 1
polyuria 1
functional recovery 1
skin damage 1
numbness 1
memory loss 1
Ill 1
hyperoxia 1
neurological disability 1
headache 1
ophthalmoplegia 1
acute stress 1
dry eye 1
decreased appetite 1
HSA 1
flushing 1
sore throat 1
myalgia 1
pelvic pain 1
Drug
NADH 36
ROS 33
lysine 19
citric acid 11
Triclosan 9
vitamin E 8
MAP 7
Cardiovasc 4
caffeine 3
ascorbate 3
Monit 3
Rosiglitazone 3
Asn 3
Alanine 3
Sodium dichloroacetate 3
Leaf 3
Fragment 3
Gleevec 2
AMC 2
Ouabain 2
Troglitazone 2
Heme 2
Retinoic acid 2
Amiloride 2
Portal 2
Itraconazole 2
Amiloride 2
Imatinib 2
NVP 2
Simvastatin 2
Glycyrrhiza 2
RAL 2
ICI 2
Red ginseng 1
GEO 1
AHF 1
PCP 1
ROC 1
ALA 1
Angiotensin II 1
Kenyan 1
Forskolin 1
CSF 1
Japanese encephalitis vaccine 1
Ranolazine 1
Ketoconazole 1
TMS 1
EE2 1
KGF 1
Hymenialdisine 1
NOV 1
Cilostazol 1
TAK 1
CaCl2 1
Taxol 1
MRC 1
Etodolac 1
OTC 1
Parkin 1
Exenatide 1
Ginseng 1
uPA 1
Nitric Oxide 1
Azithromycin 1
Bortezomib 1
Erlotinib 1
Zmax 1
Gefitinib 1
Diisopropylamine dichloroacetate 1
Rituximab 1
OTC 1
CER 1
CaCl2 1
Glucagon 1
Ranolazine 1
Nephron 1
Glycerol 1
Herceptin 1
Etoposide 1
IFN-gamma 1
Flavopiridol 1
ADM 1
niacin 1
Parkin 1
ABC 1
Asthma 1
CaCl2 1
Sorafenib 1
Fructose 1
Gel 1
Enzyme
PDK1 2238
pyruvate dehydrogenase 470
pyruvate dehydrogenase 337
pyruvate dehydrogenase 337
protein kinase 258
mitogen-activated protein kinase 175
focal adhesion kinase 148
ERK 145
protein kinase C 134
phosphatidylinositol 3-kinase 85
MEK 63
AMP-activated protein kinase 60
phosphoinositide 3-kinase 58
ACE 57
PDH 56
AMPK 46
GSK 37
lactate dehydrogenase 37
AMPK 35
CPT 34
luciferase 34
pyruvate dehydrogenase phosphatase 33
caspase-3 31
calcineurin 26
pyruvate kinase 20
hexokinase 19
superoxide dismutase 18
glutathione S-transferase 18
HK2 17
ATPase 16
phosphoenolpyruvate carboxykinase 16
phosphofructokinase 15
PARP 14
CPT 13
CPT 13
complex I 13
catalase 12
acetyl-CoA carboxylase 12
cdc2 12
STK2 12
TOR 12
IKK 12
caspase-9 11
hormone-sensitive lipase 11
citrate synthase 11
phosphoenolpyruvate carboxykinase 11
phosphoenolpyruvate carboxykinase 11
NADPH oxidase 10
prolyl hydroxylase 10
proteasome 9
phospholipase C 9
PKG 9
lipoate acetyltransferase 9
NADPH oxidase 8
glucose-6-phosphate dehydrogenase 8
pyruvate carboxylase 7
glucokinase 7
thrombin 7
protein phosphatase 2A 7
glutaminase 6
glucose-6-phosphatase 6
succinate dehydrogenase 6
acyl-CoA dehydrogenase 6
glyceraldehyde-3-phosphate dehydrogenase 6
RNA polymerase 6
caspase-8 6
ACS 6
isocitrate dehydrogenase 6
isocitrate dehydrogenase 6
lipoprotein lipase 6
phosphodiesterase 5
thymidine kinase 5
phospholipase D 5
LPL 5
APC 5
MAP 5
cytochrome oxidase 5
creatine kinase 5
alpha-ketoglutarate dehydrogenase 4
branched-chain alpha-keto acid dehydrogenase 4
NO synthase 4
trypsin 4
transcriptase 4
glutamine synthetase 4
polo-like kinase 1 4
DNA methyltransferase 4
diaphorase 4
phosphorylase 4
glyceraldehyde-3-phosphate dehydrogenase 4
6-phosphofructo-2-kinase 3
3-hydroxyacyl-CoA dehydrogenase 3
TACE 3
farnesyltransferase 3
glutathione peroxidase 3
farnesyltransferase 3
ATP synthase 3
demethylase 3
chymotrypsin 3
adenylate cyclase 3
BCKDH 3
CPR 3
AMP-activated kinase 3
diaphorase 3
STK3 3
malate dehydrogenase 3
alanine aminotransferase 3
alkaline phosphatase 3
inositol phosphatase 3
pyruvate decarboxylase 3
acyl-CoA dehydrogenase 3
glutathione synthetase 3
phospholipase A2 3
histone demethylase 2
phosphoribulokinase 2
PDE 2
CEP 2
succinyl-CoA synthetase 2
PHT 2
glutamate dehydrogenase 2
PHD 2
TPP 2
glutamate dehydrogenase 2
TdT 2
glutamate dehydrogenase 2
GRK2 2
reverse transcriptase 2
CaMKII 2
phosphorylase kinase 2
glycogenin 2
MEKK1 2
malonyl-CoA decarboxylase 2
STK11 2
aldolase 2
fructose 1,6-bisphosphatase 2
histidine kinase 2
xanthine oxidase 2
CEP 2
collagenase 2
glucose oxidase 2
ALDH 2
TPP 2
phosphoglucose isomerase 1
diacylglycerol kinase 1
alcohol dehydrogenase 1
endonuclease 1
CAD 1
transketolase 1
acyl-CoA synthetase 1
PGM 1
fumarase 1
SPC 1
neutral sphingomyelinase 1
cystathionine beta-synthase 1
acyl-CoA oxidase 1
PAH 1
SCS 1
urease 1
adenosine deaminase 1
MDR 1
glycerol-3-phosphate dehydrogenase 1
CYP7A1 1
arylsulfatase 1
adenosine deaminase 1
2,4-dienoyl-CoA reductase 1
CAD 1
topoisomerase 1
CAD 1
glyceraldehyde-3-phosphate dehydrogenase 1
aconitase 1
topoisomerase 1
cathepsin B 1
protein L-isoaspartyl methyltransferase 1
peroxidase 1
hypoxanthine-guanine phosphoribosyltransferase 1
glycine decarboxylase 1
thyroid peroxidase 1
indoleamine 2,3-dioxygenase 1
triphosphatase 1
myosin light chain kinase 1
calpain 3 1
dipeptidyl peptidase IV 1
glyceraldehyde-3-phosphate dehydrogenase 1
ADH 1
caspase-2 1
NOS 1
DNA polymerase 1
eEF2 kinase 1
flavin-containing monooxygenase 1
Mg2+-ATPase 1
aldehyde dehydrogenase 1
diacylglycerol acyltransferase 1
cysteine synthase 1
oxoglutarate dehydrogenase 1
carnosinase 1
ubiquinol-cytochrome c oxidoreductase 1
lipoxygenase 1
PTPase 1
CYP8B1 1
ALA synthase 1
peptide deformylase 1
MAT 1
Thy1 1
alpha-glucosidase 1
caspase-2 1
N-acetyltransferase 1
beta-glucuronidase 1
P-glycoprotein 1
citrate lyase 1
STK 1
xylanase 1
NADH-cytochrome b5 reductase 1
phosphatidylinositol 4-kinase 1
phenol oxidase 1
renin 1
HSD 1
NQO1 1
rhomboid protease 1
firefly luciferase 1
aspartate aminotransferase 1
3-hydroxy-3-methylglutaryl-CoA reductase 1
thymidylate synthase 1
BAT 1
myo-inositol oxygenase 1
3-hydroxyacyl-CoA dehydrogenase 1
phosphomannomutase 1
aldehyde oxidase 1
gamma-glutamylcysteine synthetase 1
hexosaminidase 1
3'-phosphatase 1
chalcone synthase 1
FAST 1
MAT 1
urease 1
arylalkylamine N-acetyltransferase 1
glycerol kinase 1
Omi/HtrA2 1
tissue plasminogen activator 1
xylanase 1
glutathione reductase 1
ceruloplasmin 1
carbonic anhydrase 1
MMP-3 1
glycerol-3-phosphate dehydrogenase 1
monoacylglycerol lipase 1
HK3 1
MMP 1
PCP 1
inositol polyphosphate 4-phosphatase 1
matrix metalloproteinase 2 1
HMG-CoA synthase 1
3-hydroxy-3-methylglutaryl coenzyme A reductase 1
urokinase-type plasminogen activator 1
lipase 1
phosphoenolpyruvate carboxylase 1
fatty acid elongase 1
15-hydroxyprostaglandin dehydrogenase 1
enolase 1
matrix metalloproteinase 9 1
phosphoglucomutase 1
aldehyde dehydrogenase 1
serum carnosinase 1
ornithine transcarbamylase 1
glyceraldehyde-3-phosphate dehydrogenase 1
myo-inositol-1-phosphate synthase 1
cathepsin G 1
phosphoglycerate kinase 1
Compound
glucose 478
oxygen 224
ATP 208
Dec 159
threonine 157
DNA 122
serine 100
acetyl-CoA 74
phosphate 72
Dichloroacetate 67
tyrosine 64
PDH 56
Insulin 52
calcium 49
alanine 49
ADP 48
ADP 46
ADP 46
sodium 43
CoA 42
MEK 36
NADH 36
water 34
NAD 33
glutamate 32
cAMP 29
TCA 29
acetate 24
NAD 24
AMP 24
MDA 24
glutamine 23
lysine 23
His 22
glycerol 22
Pyruvate 22
hydrogen 20
Asp 20
cysteine 20
Clin 20
arginine 19
MTT 19
Cardiol 18
pentose 17
pentose 17
pentose 17
pentose 17
Phosphatidylinositol 14
salt 14
nitric oxide 14
Rapamycin 13
CPT 13
CPT 13
TNF 13
2-oxoglutarate 13
methionine 13
leucine 13
TPP 11
potassium 11
Gly 10
malonyl-CoA 10
Phe 10
Mg2+ 10
Lactate 10
PAP 9
ammonium 9
palmitic acid 9
DCA 9
alloxan 9
retinoic acid 9
DCA 9
PDP 9
DOCA 9
PAP 9
iron 8
GSH 8
H2O2 8
GSH 8
N-acetylcysteine 8
Hearts 8
DEN 8
proline 8
nitrogen 7
Hearts 7
boron 7
Wortmannin 7
Adriamycin 6
MAP 6
ADR 6
palmitic acid 6
tryptophan 6
zinc 6
urea 6
NH2 6
GTP 6
DDP 6
acetamide 6
acetamide 6
SDS 6
bromide 6
Serine 6
valine 6
DMSO 6
sulfate 6
ACS 6
ACS 6
COX 6
nicotinamide 6
PMA 5
AGE 5
tryptophan 5
pyrimidine 5
Metformin 5
tryptophan 5
aspartic acid 5
pyrimidine 5
tryptophan 5
Metformin 5
Quercetin 5
cGMP 5
aspartic acid 5
Panam 5
CO2 5
dUTP 5
Melatonin 5
aspartic acid 5
ethanol 5
aspartic acid 5
TOF 4
glucose-6-phosphate 4
TSC 4
Celecoxib 4
glutamic acid 4
Pro-Gly 4
Curcumin 4
5-FU 4
galactose 4
PPI 4
phosphocreatine 4
WY-14,643 4
BCR 4
L-carnitine 4
FFA 3
Tamoxifen 3
Austin 3
silver 3
Cholesterol 3
Ang II 3
cadmium 3
caffeine 3
cobalt 3
CAP 3
uridine 3
Tyrosine 3
NADPH 3
DEHP 3
ABL 3
CAT 3
LY 294002 3
Adenosine 3
CAT 3
Betulinic acid 3
Alanine 3
Thrombin 3
2-ethylhexyl 3
cyanide 3
pyridine 3
Carnosine 3
TSH 3
aldosterone 3
quinazoline 3
CAT 3
2-ethylhexyl 3
CAM 3
TACE 3
Tamoxifen 3
2-ethylhexyl 3
NADPH 3
quinazoline 3
DPG 3
5-HT 3
PGE2 3
acetic acid 3
STZ 3
LIN 3
formaldehyde 2
nicotinic acid 2
Heme 2
stearic acid 2
GlcNAc 2
Sulforaphane 2
palmitoyl-CoA 2
DEAE 2
adenosylmethionine 2
L-threonine 2
dihydrolipoamide 2
TPP 2
manganese 2
Sucrose 2
nickel 2
Cyclosporine 2
isoleucine 2
Progesterone 2
DBP 2
Androgen 2
Arsenic 2
naphthalene 2
nicotinic acid 2
hydroxyglutarate 2
COI 2
nicotinic acid 2
Rottlerin 2
isocitrate 2
pentacene 2
Ile 2
NADP 2
ethyl acetate 2
Monocrotaline 2
alpha-ketoisocaproate 2
Cereb 2
Baicalein 2
Neuronal 2
L-DOPA 2
GABA 2
benzene 2
AICAR 2
AICAR 2
iodine 2
TPP 2
ITC 2
C-3 2
succinic acid 2
GABA 2
Amiloride 2
Rottlerin 2
nitrate 2
Pac 2
CoQ 2
Dexamethasone 2
MAL 2
Rottlerin 2
Lip 2
Estrogen 2
EMS 2
Collagen 2
phosphoric acid 2
asparagine 2
carbonate 2
Apigenin 2
isoleucine 2
Thiamine 2
adenylate 2
Histone 2
PDB 2
Staurosporine 2
Thyroid 2
CAP 2
TPCK 2
stearic acid 2
Pima 2
2-methylpropanamide 2
COS 2
Staurosporine 2
FK506 2
DBI 2
UTP 2
PHT 2
stearic acid 2
ACTH 2
Glutamate 2
PMA 2
Temozolomide 2
TEM 2
retinol 2
fluorine 2
Flux 2
nicotinic acid 2
ICI 2
Cbl 2
Ouabain 2
H2S 2
homocysteine 2
butyric acid 2
MIA 2
DBP 2
Losartan 2
Diabetol 1
alcohol dehydrogenase 1
TCM 1
chloroform 1
DPPH 1
Palmitoyl-L-carnitine 1
(-)-Epigallocatechin 1
DPI 1
Phenylephrine 1
ACM 1
Amphetamine 1
MAOA 1
Alizarin 1
hydroxycinnamic acid 1
Ferulic acid 1
CPB 1
Dextran 1
PNP 1
2-mercaptoethanol 1
BIP 1
thiourea 1
formaldehyde 1
Anacardic acid 1
Acriflavine 1
aflatoxin B1 1
DX-52-1 1
MNU 1
Dibenzoylmethane 1
PCP 1
Cortisol 1
40S 1
2-(dimethylamino)ethyl 1
bromoacetic acid 1
Propionate 1
Estradiol 1
MCA 1
2-oxobutyrate 1
8-quinolinol 1
heptadecanoic acid 1
triphenylphosphine 1
decanoic acid 1
TBE 1
cholestane 1
succinic acid 1
TCH 1
succinic acid 1
Thromboxane 1
pyrrolidine 1
Putrescine 1
piperazine 1
NTA 1
Flavonoid 1
Coenzyme A 1
Cefotaxime 1
Eugenol 1
Deoxyelephantopin 1
Letter 1
formic acid 1
MGBG 1
Atorvastatin 1
PHB 1
Hordenine 1
isonicotinic acid 1
Morusin 1
ethylbenzene 1
CCP 1
piperidine 1
Testosterone 1
2-oxopropanamide 1
indole-3-carbinol 1
Amide 1
NPPB 1
Tetrandrine 1
phosphorus 1
DNP 1
Fructose 1
Calcitonin 1
hydroxide 1
Vitamin D3 1
Gemcitabine 1
MNU 1
Vimentin 1
Adrenal 1
Glucagon 1
PPi 1
MPC 1
Ruthenium 1
ASA 1
Cobalt 1
cholestane 1
DGE 1
Thymidine 1
MDR 1
Isoproterenol 1
Phorbol 1
Plumbagin 1
Cysteine 1
Estrogen 1
octanoyl-CoA 1
Lac 1
GA3 1
diacetate 1
HBB 1
Leflunomide 1
hexanoic acid 1
3-hydroxy-2-butanone 1
1H-pyrrole-2,5-dione 1
THP 1
Methionine 1
Keratin 1
1H-pyrazolo[3,4-d]pyrimidine 1
Phenylalanine 1
DPT 1
DHA 1
Amphetamine 1
Angiotensin II 1
PEI 1
Carbon 1
chromium 1
quinoline 1
MBT 1
Ferulic acid 1
Testosterone 1
TXA2 1
8-OHdG 1
ADP-ribose 1
Xenon 1
Diazepam 1
octanoic acid 1
aminomethyl 1
Ketoconazole 1
Ceftriaxone 1
BLM 1
Fusaric acid 1
Tiron 1
MPA 1
superoxide radical 1
DHA 1
TME 1
acridine 1
malonic acid 1
Theophylline 1
CIT 1
dipropyl 1
formic acid 1
TEC 1
Pachymic acid 1
Vasopressin 1
Tetrandrine 1
succinic acid 1
formic acid 1
3-hydroxyanthranilic acid 1
Isoform 1
heptadecanoic acid 1
GM1 1
MOD 1
hydroquinone 1
Casein 1
phosphoserine 1
TCPA 1
Diclofenac 1
Tetrandrine 1
PIN 1
NIX 1
piperidine 1
Bradykinin 1
Sodium 1
BUdR 1
DSS 1
Arachidonic acid 1
Kojic acid 1
Biotin 1
Resveratrol 1
Luteolin 1
Caffeic acid phenethyl ester 1
Flavin 1
pyrrolidine 1
cis-vaccenic acid 1
OHB 1
Glycogen synthase 1
MGBG 1
PAS 1
CBDCA 1
AMPA 1
CBDCA 1
Isoliquiritigenin 1
Tetrandrine 1
Oleanolic acid 1
chalcone 1
Hymenialdisine 1
Glutamine 1
AA861 1
Asiaticoside 1
Salinomycin 1
Ochratoxin A 1
TCM 1
resorcinol 1
DON 1
Tanshinone 1
Succinyl-CoA 1
GSSG 1
Carnitine 1
DGE 1
Glyoxylate 1
1H-imidazole 1
AAA 1
sodium chloride 1
Ciprofloxacin 1
Forskolin 1
Hematoxylin 1
DGE 1
acetonitrile 1
H2S 1
4-Hydroxynonenal 1
Celastrol 1
2,2-dichloroacetamide 1
formic acid 1
gamma-aminobutyric acid 1
TBI 1
decanoic acid 1
isopropanol 1
Pachypodol 1
Haloperidol 1
PEG 1
toluene 1
octanoic acid 1
THP 1
2-(dimethylamino)ethyl 1
Digoxin 1
pyrene 1
Homocysteine 1
phenol 1
DCM 1
Rifampicin 1
kaempferol 1
Dihydromyricetin 1
quinoline 1
ubiquinone 1
Vitamin D3 1
MgCl2 1
Epigallocatechin gallate 1
phenazine 1
Fluo-3 1
GRP-1 1
difluoroacetic acid 1
MTS 1
Cinnamaldehyde 1
CaCl2 1
Optimal 1
6-12 1
TEA 1
C9H10O3 1
Guo 1
L-leucine 1
HCl 1
Digitonin 1
2-Deoxy-D-glucose 1
Oleic acid 1
acrylic acid 1
octanoic acid 1
merocyanine 540 1
DDT 1
Shikonin 1
KIV 1
Phenethyl isothiocyanate 1
TCDD 1
ammonia 1
Emodin 1
DHA 1
PEG 1
fMet 1
MK801 1
Paclitaxel 1
hydrazine 1
Phytosphingosine 1
PGE 1
1-chloro-2,4-dinitrobenzene 1
celastrol 1
formic acid 1
formic acid 1
MPA 1
PCN 1
dicarboxylic acid 1
AMD 1
CaO 1
VP-16 1
DAG 1
ACN 1
Carvacrol 1
T11 1
ubiquinol 1
octanoic acid 1
Lead 1
Glycogen 1
DCC 1
S152 1
Betulin 1
Diacetoxyscirpenol 1
MPA 1
SPD 1
formic acid 1
Gemcitabine 1
PAH 1
Diltiazem 1
Triton X-100 1
Cyt 1
Diltiazem 1
N-acetylaspartate 1
DAD 1
PEI 1
Eugenol 1
prostacyclin 1
Diabetol 1
BSO 1
formic acid 1
TNM 1
Ach 1
itaconic acid 1
methane 1
Sorbitol 1
selenium 1
octanoic acid 1
chlorine 1
succinic acid 1
GDP 1
Fusaric acid 1
PH2 1
CBS 1
Homocysteine 1
SOA 1
TTS 1
TEA 1
Bacitracin 1
BNP 1
Fusaric acid 1
Triton 1
DES 1
formic acid 1
formic acid 1
Valine 1
Ruthenium 1
Sesamin 1
pyrazine 1
ASK 1