Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:2.7.11.2 (PDK1)
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Human Gene/Protein
alcohol dehydrogenase, iron containing, 1 13.8
pyruvate dehydrogenase kinase 13.8
SYT16 13.8
aldose reductase-related protein 13.8
SGK494 13.8
Ankyrin repeat domain-containing protein 22 13.8
acyl-CoA synthetase short-chain family member 1 13.8
actinin, alpha 2 13.8
STK1 13.8
PDK4 13.8
OXCT protein 13.8
branched chain alpha-ketoacid dehydrogenase kinase 13.8
CRHSP24 13.8
PDK3 13.8
PDK2 13.8
SRM160 13.8
PDK1 13.8
PDK 13.6
stk2 13.2
PDK4 protein 13.0
more...
Disease
Hyper IgM syndrome 10.1
CEBPG 9.9
SHORT syndrome 9.8
Familial dilated cardiomyopathy 9.3
PDH deficiency 8.9
Neovascular age-related macular degeneration 8.8
Endometrioid carcinoma 8.6
Parvovirus infection 8.4
Late pregnancy 8.3
AUTS2 8.0
Calcium deficiency 7.9
PDP 7.6
PDC 7.6
ARTS 7.5
Transient cerebral ischemia 7.3
adult brain tumor 7.3
FED 7.1
recurrent NSCLC 7.1
hereditary sensory neuropathy 7.0
HRD 6.9
more...
Symptom
starvation 5.3
eye pain 5.2
neurological disability 3.9
cachexia 3.7
decreased appetite 3.6
skin damage 3.2
exhaustion 3.1
dry eye 2.4
sore throat 2.4
hunger 2.3
HSA 2.2
acidity 2.2
polyuria 2.2
ophthalmoplegia 2.1
memory loss 2.0
pelvic pain 1.8
acute stress 1.6
numbness 1.5
hyperoxia 1.4
hypothermia 1.3
more...
Drug
Diisopropylamine dichloroacetate 12.8
Sodium dichloroacetate 10.8
Hymenialdisine 10.5
Japanese encephalitis vaccine 7.7
Red ginseng 6.9
Etodolac 6.8
RAL 6.8
Triclosan 6.3
Flavopiridol 6.1
NOV 6.1
Ranolazine 5.8
Ranolazine 5.8
Zmax 5.8
Troglitazone 5.7
Rosiglitazone 5.7
CER 5.7
Exenatide 5.5
Cilostazol 5.1
AHF 4.9
KGF 4.9
more...
Enzyme
PDK1 13.8
pyruvate dehydrogenase phosphatase 12.4
BCKDH 10.9
STK2 10.9
pyruvate dehydrogenase 10.4
pyruvate dehydrogenase 10.4
pyruvate dehydrogenase 10.2
PDH 10.2
lipoate acetyltransferase 9.7
HK3 9.0
STK3 9.0
HK2 8.8
inositol polyphosphate 4-phosphatase 8.6
serum carnosinase 8.0
glycogenin 7.6
malonyl-CoA decarboxylase 7.6
myo-inositol oxygenase 7.5
protein L-isoaspartyl methyltransferase 7.5
CYP8B1 7.3
branched-chain alpha-keto acid dehydrogenase 7.2
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Compound
C9H10O3 11.8
GRP-1 10.6
Pachypodol 10.5
Dichloroacetate 10.4
Palmitoyl-L-carnitine 10.0
Pachymic acid 10.0
TCPA 9.9
S152 9.9
2-oxopropanamide 9.9
PDH 9.6
Deoxyelephantopin 9.6
2-methylpropanamide 9.5
difluoroacetic acid 9.3
Hymenialdisine 9.2
Hordenine 9.0
2,2-dichloroacetamide 8.9
Morusin 8.9
Phytosphingosine 8.8
WY-14,643 8.7
1H-pyrazolo[3,4-d]pyrimidine 8.4
more...