Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts: Gene/Protein Disease Symptom Drug Enzyme Compound   Target Concepts: Gene/Protein Disease Symptom Drug Enzyme Compound

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Query: EC:2.7.11.2 (PDK1)
2,238 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .

Human Gene/Protein PDK1 980 pyruvate dehydrogenase kinase 637 PDK 528 pyruvate dehydrogenase 348 insulin 327 PDK4 300 PI3K 256 AKT 223 Mol 220 mTOR 210 ATP 208 pyruvate dehydrogenase complex 201 Sep 143 PDK2 129 PKB 105 phosphatase 101 PTEN 95 protein kinase B 87 PDH 86 phosphatidylinositol 3-kinase 85 more...

Disease cancer 490 tumor 267 diabetes 127 breast cancer 75 obesity 70 tumor growth 68 tumorigenesis 67 type 2 diabetes 47 carcinoma 42 ischemia 41 hepatocellular carcinoma 39 tumor progression 37 colorectal cancer 35 lung cancer 33 heart failure 31 prostate cancer 30 hyperglycemia 28 glioblastoma 28 carcinogenesis 25 colon cancer 25 more...

Symptom starvation 70 exhaustion 8 fatigue 6 pain 6 acidity 5 cachexia 5 weakness 5 seizures 4 overweight 3 hypothermia 3 hunger 2 tremor 2 anesthesia 2 collapse 2 ataxia 2 anorexia 2 dry eye 1 functional recovery 1 skin damage 1 numbness 1 more...

Drug NADH 36 ROS 33 lysine 19 citric acid 11 Triclosan 9 vitamin E 8 MAP 7 Cardiovasc 4 ascorbate 3 Monit 3 Sodium dichloroacetate 3 caffeine 3 Leaf 3 Alanine 3 Fragment 3 Asn 3 Rosiglitazone 3 Heme 2 Simvastatin 2 Portal 2 more...

Enzyme PDK1 2238 pyruvate dehydrogenase 470 pyruvate dehydrogenase 337 pyruvate dehydrogenase 337 protein kinase 258 mitogen-activated protein kinase 175 focal adhesion kinase 148 ERK 145 protein kinase C 134 phosphatidylinositol 3-kinase 85 MEK 63 AMP-activated protein kinase 60 phosphoinositide 3-kinase 58 ACE 57 PDH 56 AMPK 46 lactate dehydrogenase 37 GSK 37 AMPK 35 luciferase 34 more...

Compound glucose 478 oxygen 224 ATP 208 Dec 159 threonine 157 DNA 122 serine 100 acetyl-CoA 74 phosphate 72 Dichloroacetate 67 tyrosine 64 PDH 56 Insulin 52 calcium 49 alanine 49 ADP 48 ADP 46 ADP 46 sodium 43 CoA 42 more...

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