Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:2.7.11.2 (PDK1)
 2,238 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
PDK1 0.438
pyruvate dehydrogenase kinase 0.284
PDK 0.212
PDK4 0.134
PDK2 0.058
PDK3 0.018
pyruvate dehydrogenase 0.014
pyruvate dehydrogenase complex 0.010
PDK4 protein 0.009
STK1 0.009
PDH 0.005
PDP2 0.003
Pyruvate dehydrogenase 0.002
PKB 0.002
PDK1 protein 0.002
SGK3 0.001
PI3K 0.001
SGK1 0.001
pyruvate dehydrogenase kinase 4 0.001
STK2 0.001
SGK 0.001
lactate dehydrogenase A 0.001
PDHK2 0.001
SGK494 0.001
branched chain alpha-ketoacid dehydrogenase kinase 0.001
AKT 0.001
LDHA 0.001
PDPK1 0.001
stk2 0.001
3-phosphoinositide-dependent protein kinase 1 0.001
mTOR 0.001
S6K1 0.001
PRK2 0.001
SRM160 0.001
aldose reductase-related protein 0.001
SYT16 0.001
actinin, alpha 2 0.001
CRHSP24 0.001
OXCT protein 0.001
Ankyrin repeat domain-containing protein 22 0.001
acyl-CoA synthetase short-chain family member 1 0.001
alcohol dehydrogenase, iron containing, 1 0.001
protein kinase B 0.000
PTEN 0.000
CSRNP3 0.000
CORO2A 0.000
ATP1G1 0.000
epithelial protein lost in neoplasm beta 0.000
phosphoinositide-3-kinase, catalytic, beta polypeptide 0.000
PCYT1B 0.000
TBC1D30 0.000
CRIK 0.000
PFKFB4 0.000
COX4I2 0.000
PDHC 0.000
PANK4 0.000
stem cell tyrosine kinase 1 0.000
PLEKHG4B 0.000
BRP44 0.000
PKM2 0.000
RPS6KB2 0.000
RSK 0.000
ZNF367 0.000
ACSS1 0.000
PH domain 0.000
ZBTB2 0.000
CPT1 0.000
phosphatidylinositol 3-kinase 0.000
mitochondrial fission regulator 1 0.000
tolloid-like protein 0.000
NEDL2 0.000
BRP44L 0.000
PLXDC2 0.000
RPS6KA2 0.000
PGC 0.000
MYO1B 0.000
cytokine-independent survival kinase 0.000
GRAP 0.000
phosphoinositide 3-kinase 0.000
HK2 0.000
pyruvate kinase M2 0.000
PHLPPL 0.000
apoptosis facilitator 0.000
Pak-2 0.000
pyruvate dehydrogenase alpha subunit 0.000
INPP4B protein 0.000
THBS1 protein 0.000
bpoz 0.000
VPP1 0.000
NFKBIL2 0.000
UCP3 0.000
TORC2 0.000
PIF 0.000
SGK2 0.000
PDHA1 0.000
RSK1 0.000
ribosomal S6 kinase 0.000
insulin 0.000
GNGT2 0.000
FRMD8 0.000
FASTK 0.000
OSBPL3 0.000
C1QTNF3 0.000
CHPPR 0.000
CSNK1G1 0.000
DAPL1 0.000
hMAP126 0.000
pleckstrin 0.000
SIN1 0.000
STK3 0.000
CTMP 0.000
ANGPTL4 0.000
PIP3 0.000
ACN9 0.000
BTNL9 0.000
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 0.000
TMEM129 0.000
HIST1H2AC 0.000
KIAA1324 0.000
ZPR9 0.000
SYT5 0.000
PRK1 0.000
Pyruvate kinase M2 0.000
hexokinase 2 0.000
PKC 0.000
Nedd4-2 0.000
OXCT 0.000
ADHFE1 0.000
tenascin XB 0.000
CRIP2 0.000
CDC2L5 0.000
PKB beta 0.000
TARSH 0.000
MOGAT2 0.000
AGXT2L1 0.000
PKN 0.000
phosphatase 0.000
ORP9 0.000
MUSTN1 0.000
EIF4H 0.000
CALML3 0.000
LPGAT1 0.000
carboxypeptidase Z 0.000
PI3 0.000
hexokinase II 0.000
glucose transporter 0.000
nuclear factor of kappa light chain gene 0.000
OTUD1 0.000
serum/glucocorticoid regulated kinase 0.000
TBCK 0.000
TSPEAR 0.000
ABLIM 0.000
BNIP2 0.000
RBPMS2 0.000
BMCC1 0.000
GSTZ1 0.000
TNFAIP8L3 0.000
MKNK1 0.000
ATP 0.000
p70 0.000
more...
Disease
SHORT syndrome 0.000
Hyper IgM syndrome 0.000
CEBPG 0.000
cancer 0.000
PDC 0.000
PDH deficiency 0.000
Familial dilated cardiomyopathy 0.000
PDP 0.000
Neovascular age-related macular degeneration 0.000
tumor 0.000
Endometrioid carcinoma 0.000
Parvovirus infection 0.000
Late pregnancy 0.000
tumor growth 0.000
tumorigenesis 0.000
AUTS2 0.000
Calcium deficiency 0.000
diabetes 0.000
ARTS 0.000
lactic acidosis 0.000
glioblastoma 0.000
Transient cerebral ischemia 0.000
SCD 0.000
adult brain tumor 0.000
obesity 0.000
type 2 diabetes 0.000
FED 0.000
RP11 0.000
recurrent NSCLC 0.000
breast cancer 0.000
tumor progression 0.000
hereditary sensory neuropathy 0.000
HRD 0.000
recurrent endometrial cancer 0.000
FAS 0.000
Peritoneum 0.000
Peritoneum 0.000
DMM 0.000
hyperglycemia 0.000
cancer angiogenesis 0.000
cancer regression 0.000
Pleura 0.000
Ileum 0.000
Pleura 0.000
tuberous sclerosis 0.000
PSN 0.000
colorectal cancer 0.000
colon cancer 0.000
non-small cell lung cancer 0.000
Dengue hemorrhagic fever 0.000
Diabetic peripheral neuropathy 0.000
hemiparkinsonism 0.000
hepatocellular carcinoma 0.000
dengue 0.000
Postoperative cognitive dysfunction 0.000
ischemia 0.000
glioma 0.000
hyperinsulinemia 0.000
Malignant glioma 0.000
MSF 0.000
PARK2 0.000
HTS 0.000
Glioblastoma 0.000
prostate cancer 0.000
lung cancer 0.000
AGS 0.000
pancreatic cancer 0.000
NCR 0.000
Autosomal recessive polycystic kidney disease 0.000
CAE 0.000
hypoglycemic coma 0.000
CMT1A 0.000
Hippel 0.000
heart failure 0.000
MCF 0.000
hyperthyroidism 0.000
OPA1 0.000
gastric cancer 0.000
glioblastoma multiforme 0.000
LIN 0.000
CYLD 0.000
Estrogen deficiency 0.000
glucose intolerance 0.000
Charcot-Marie-Tooth disease 0.000
carcinoma 0.000
Pulmonary arterial hypertension 0.000
metastatic ovarian cancer 0.000
Neuroblastoma 0.000
Neuroblastoma 0.000
large cell carcinomas 0.000
Liver regeneration 0.000
Leigh syndrome 0.000
carcinogenesis 0.000
Cholangiocarcinoma 0.000
CEP 0.000
diabetic cardiomyopathy 0.000
CLS 0.000
HGF 0.000
Vesicular stomatitis 0.000
RBS 0.000
neuroblastoma 0.000
Cholangiocarcinoma 0.000
Peutz-Jeghers syndrome 0.000
adenocarcinoma 0.000
FBS 0.000
polycythemia 0.000
Blocking 0.000
AS1 0.000
sepsis 0.000
proliferative vitreoretinopathy 0.000
ovarian cancer 0.000
Diaphragm 0.000
polycystic kidney 0.000
brain cancer 0.000
sepsis 0.000
TEC 0.000
heroin addiction 0.000
acute myeloid leukemia 0.000
NS3 0.000
eastern equine encephalitis 0.000
ovarian dysfunction 0.000
metabolic syndrome 0.000
vascular obstruction 0.000
right heart failure 0.000
brain tumor 0.000
intestinal cancer 0.000
NF2 0.000
Ovarian Cancer 0.000
peripheral neuropathy 0.000
tumor angiogenesis 0.000
biliary tract cancer 0.000
inflammatory breast cancer 0.000
fatty liver 0.000
WSN 0.000
WSN 0.000
ganglioglioma 0.000
leukemia 0.000
EMT 0.000
NPS 0.000
cervical cancer 0.000
sickle cell disease 0.000
mammary tumor 0.000
hypernatremia 0.000
HBB 0.000
HBB 0.000
HBB 0.000
lipoatrophy 0.000
syndrome X 0.000
Worms 0.000
dilated cardiomyopathy 0.000
primary pulmonary hypertension 0.000
COL2A1 0.000
MRS 0.000
aggressiveness 0.000
anal cancer 0.000
pulmonary insufficiency 0.000
lipid disorder 0.000
familial cancer 0.000
anal cancer 0.000
NLS 0.000
more...
Symptom
starvation 0.000
eye pain 0.000
cachexia 0.000
exhaustion 0.000
neurological disability 0.000
decreased appetite 0.000
skin damage 0.000
acidity 0.000
hunger 0.000
dry eye 0.000
sore throat 0.000
HSA 0.000
polyuria 0.000
ophthalmoplegia 0.000
memory loss 0.000
pelvic pain 0.000
weakness 0.000
fatigue 0.000
hypothermia 0.000
acute stress 0.000
numbness 0.000
hyperoxia 0.000
anorexia 0.000
flushing 0.000
myalgia 0.000
overweight 0.000
ataxia 0.000
tremor 0.000
Ill 0.000
collapse 0.000
seizures 0.000
functional recovery 0.000
pain 0.000
anesthesia 0.000
headache 0.000
Drug
Diisopropylamine dichloroacetate 0.000
Sodium dichloroacetate 0.000
Hymenialdisine 0.000
Triclosan 0.000
NADH 0.000
ROS 0.000
Japanese encephalitis vaccine 0.000
RAL 0.000
Red ginseng 0.000
Etodolac 0.000
Rosiglitazone 0.000
Flavopiridol 0.000
NOV 0.000
Troglitazone 0.000
Ranolazine 0.000
Ranolazine 0.000
Zmax 0.000
citric acid 0.000
CER 0.000
Exenatide 0.000
Cilostazol 0.000
NVP 0.000
AHF 0.000
KGF 0.000
AMC 0.000
Fragment 0.000
lysine 0.000
Glycyrrhiza 0.000
Gleevec 0.000
Amiloride 0.000
Alanine 0.000
OTC 0.000
Simvastatin 0.000
Erlotinib 0.000
Amiloride 0.000
vitamin E 0.000
Itraconazole 0.000
MAP 0.000
TAK 0.000
Ketoconazole 0.000
OTC 0.000
Imatinib 0.000
Ouabain 0.000
Etoposide 0.000
Gefitinib 0.000
Azithromycin 0.000
Heme 0.000
Bortezomib 0.000
Retinoic acid 0.000
Sorafenib 0.000
GEO 0.000
Ginseng 0.000
Parkin 0.000
Parkin 0.000
Portal 0.000
Fructose 0.000
uPA 0.000
Herceptin 0.000
Glycerol 0.000
TMS 0.000
ICI 0.000
Nitric Oxide 0.000
Forskolin 0.000
ALA 0.000
Rituximab 0.000
Asn 0.000
ADM 0.000
Taxol 0.000
MRC 0.000
Kenyan 0.000
PCP 0.000
Glucagon 0.000
niacin 0.000
Angiotensin II 0.000
caffeine 0.000
Leaf 0.000
ascorbate 0.000
CaCl2 0.000
CaCl2 0.000
CaCl2 0.000
ROC 0.000
EE2 0.000
Monit 0.000
ABC 0.000
Gel 0.000
Nephron 0.000
Asthma 0.000
IFN-gamma 0.000
CSF 0.000
Cardiovasc 0.000
Enzyme
PDK1 0.999
pyruvate dehydrogenase 0.018
pyruvate dehydrogenase 0.015
pyruvate dehydrogenase 0.015
pyruvate dehydrogenase phosphatase 0.006
PDH 0.002
STK2 0.001
protein kinase 0.000
phosphatidylinositol 3-kinase 0.000
lipoate acetyltransferase 0.000
BCKDH 0.000
phosphoinositide 3-kinase 0.000
HK2 0.000
focal adhesion kinase 0.000
protein kinase C 0.000
mitogen-activated protein kinase 0.000
AMP-activated protein kinase 0.000
CPT 0.000
MEK 0.000
ERK 0.000
GSK 0.000
AMPK 0.000
ACE 0.000
STK3 0.000
AMPK 0.000
HK3 0.000
TOR 0.000
inositol polyphosphate 4-phosphatase 0.000
pyruvate kinase 0.000
hexokinase 0.000
serum carnosinase 0.000
prolyl hydroxylase 0.000
hormone-sensitive lipase 0.000
phosphofructokinase 0.000
branched-chain alpha-keto acid dehydrogenase 0.000
phosphoenolpyruvate carboxykinase 0.000
CPT 0.000
glycogenin 0.000
malonyl-CoA decarboxylase 0.000
acetyl-CoA carboxylase 0.000
CPT 0.000
lactate dehydrogenase 0.000
protein L-isoaspartyl methyltransferase 0.000
myo-inositol oxygenase 0.000
6-phosphofructo-2-kinase 0.000
inositol phosphatase 0.000
CYP8B1 0.000
calcineurin 0.000
pyruvate carboxylase 0.000
PKG 0.000
2,4-dienoyl-CoA reductase 0.000
PHT 0.000
rhomboid protease 0.000
IKK 0.000
acyl-CoA dehydrogenase 0.000
AMP-activated kinase 0.000
phosphoenolpyruvate carboxykinase 0.000
phosphoenolpyruvate carboxykinase 0.000
citrate synthase 0.000
luciferase 0.000
carnosinase 0.000
myo-inositol-1-phosphate synthase 0.000
caspase-3 0.000
STK 0.000
LPL 0.000
glutaminase 0.000
oxoglutarate dehydrogenase 0.000
3-hydroxyacyl-CoA dehydrogenase 0.000
ubiquinol-cytochrome c oxidoreductase 0.000
glutathione synthetase 0.000
3'-phosphatase 0.000
glucokinase 0.000
complex I 0.000
succinyl-CoA synthetase 0.000
protein phosphatase 2A 0.000
acyl-CoA dehydrogenase 0.000
cdc2 0.000
TACE 0.000
alpha-ketoglutarate dehydrogenase 0.000
STK11 0.000
caspase-9 0.000
pyruvate decarboxylase 0.000
phosphoribulokinase 0.000
eEF2 kinase 0.000
phosphomannomutase 0.000
PARP 0.000
polo-like kinase 1 0.000
peptide deformylase 0.000
glutathione S-transferase 0.000
glucose-6-phosphatase 0.000
isocitrate dehydrogenase 0.000
fatty acid elongase 0.000
farnesyltransferase 0.000
citrate lyase 0.000
isocitrate dehydrogenase 0.000
CEP 0.000
Omi/HtrA2 0.000
fructose 1,6-bisphosphatase 0.000
NADPH oxidase 0.000
farnesyltransferase 0.000
PHD 0.000
glucose-6-phosphate dehydrogenase 0.000
GRK2 0.000
phosphorylase kinase 0.000
ALDH 0.000
phospholipase D 0.000
histone demethylase 0.000
calpain 3 0.000
diaphorase 0.000
glyceraldehyde-3-phosphate dehydrogenase 0.000
HMG-CoA synthase 0.000
CEP 0.000
NADPH oxidase 0.000
NADH-cytochrome b5 reductase 0.000
caspase-8 0.000
glycine decarboxylase 0.000
TPP 0.000
lipoprotein lipase 0.000
cysteine synthase 0.000
15-hydroxyprostaglandin dehydrogenase 0.000
TPP 0.000
superoxide dismutase 0.000
succinate dehydrogenase 0.000
arylalkylamine N-acetyltransferase 0.000
neutral sphingomyelinase 0.000
phosphatidylinositol 4-kinase 0.000
monoacylglycerol lipase 0.000
3-hydroxyacyl-CoA dehydrogenase 0.000
glycerol kinase 0.000
phospholipase C 0.000
aldehyde oxidase 0.000
FAST 0.000
caspase-2 0.000
DNA methyltransferase 0.000
glutamine synthetase 0.000
caspase-2 0.000
MAP 0.000
MEKK1 0.000
BAT 0.000
thymidine kinase 0.000
TdT 0.000
phenol oxidase 0.000
diacylglycerol acyltransferase 0.000
phosphorylase 0.000
ATPase 0.000
cystathionine beta-synthase 0.000
acyl-CoA oxidase 0.000
cytochrome oxidase 0.000
CYP7A1 0.000
diacylglycerol kinase 0.000
SCS 0.000
PTPase 0.000
ALA synthase 0.000
glyceraldehyde-3-phosphate dehydrogenase 0.000
histidine kinase 0.000
flavin-containing monooxygenase 0.000
3-hydroxy-3-methylglutaryl-CoA reductase 0.000
fumarase 0.000
malate dehydrogenase 0.000
proteasome 0.000
more...
Compound
Dichloroacetate 0.003
PDH 0.001
acetyl-CoA 0.000
glucose 0.000
C9H10O3 0.000
threonine 0.000
GRP-1 0.000
Pachypodol 0.000
ATP 0.000
Pyruvate 0.000
Palmitoyl-L-carnitine 0.000
Pachymic acid 0.000
S152 0.000
TCPA 0.000
2-oxopropanamide 0.000
2-methylpropanamide 0.000
PDP 0.000
Deoxyelephantopin 0.000
WY-14,643 0.000
difluoroacetic acid 0.000
serine 0.000
Hymenialdisine 0.000
Hordenine 0.000
oxygen 0.000
DCA 0.000
DCA 0.000
2,2-dichloroacetamide 0.000
Morusin 0.000
CoA 0.000
Phytosphingosine 0.000
MEK 0.000
TCA 0.000
Insulin 0.000
1H-pyrazolo[3,4-d]pyrimidine 0.000
Dibenzoylmethane 0.000
Phosphatidylinositol 0.000
Anacardic acid 0.000
malonyl-CoA 0.000
NADH 0.000
TPP 0.000
CPT 0.000
DEN 0.000
DX-52-1 0.000
ADP 0.000
ADP 0.000
Rapamycin 0.000
CPT 0.000
ADP 0.000
Fusaric acid 0.000
Fusaric acid 0.000
Wortmannin 0.000
LY 294002 0.000
Fusaric acid 0.000
Betulinic acid 0.000
pentose 0.000
pentose 0.000
DOCA 0.000
pentose 0.000
Asiaticoside 0.000
Succinyl-CoA 0.000
Monocrotaline 0.000
pentose 0.000
dihydrolipoamide 0.000
NAD 0.000
tyrosine 0.000
Diacetoxyscirpenol 0.000
Acriflavine 0.000
TSC 0.000
DBI 0.000
Rottlerin 0.000
NIX 0.000
AGE 0.000
PHT 0.000
bromoacetic acid 0.000
alanine 0.000
Rottlerin 0.000
Phenethyl isothiocyanate 0.000
Rottlerin 0.000
Betulin 0.000
Kojic acid 0.000
NAD 0.000
PAP 0.000
PAP 0.000
Carnosine 0.000
phosphate 0.000
Dihydromyricetin 0.000
2-Deoxy-D-glucose 0.000
2-oxoglutarate 0.000
Celecoxib 0.000
MDA 0.000
alloxan 0.000
TPCK 0.000
Isoliquiritigenin 0.000
Hearts 0.000
AA861 0.000
KIV 0.000
Sesamin 0.000
glutamine 0.000
octanoyl-CoA 0.000
DGE 0.000
DGE 0.000
DGE 0.000
TACE 0.000
Baicalein 0.000
8-quinolinol 0.000
cis-vaccenic acid 0.000
Glyoxylate 0.000
Pro-Gly 0.000
DNA 0.000
Lactate 0.000
Salinomycin 0.000
Plumbagin 0.000
heptadecanoic acid 0.000
(-)-Epigallocatechin 0.000
Hearts 0.000
Caffeic acid phenethyl ester 0.000
ASK 0.000
2-oxobutyrate 0.000
heptadecanoic acid 0.000
MGBG 0.000
3-hydroxy-2-butanone 0.000
MGBG 0.000
Tetrandrine 0.000
Tetrandrine 0.000
Tetrandrine 0.000
Tetrandrine 0.000
COX 0.000
Cinnamaldehyde 0.000
Digitonin 0.000
cAMP 0.000
Shikonin 0.000
4-Hydroxynonenal 0.000
BIP 0.000
AMP 0.000
glutamate 0.000
Serine 0.000
TCH 0.000
merocyanine 540 0.000
acetamide 0.000
PH2 0.000
acetamide 0.000
alpha-ketoisocaproate 0.000
Bacitracin 0.000
glycerol 0.000
Oleanolic acid 0.000
TME 0.000
Asp 0.000
MTT 0.000
Leflunomide 0.000
Celastrol 0.000
Dec 0.000
Apigenin 0.000
PPI 0.000
Sulforaphane 0.000
1H-pyrrole-2,5-dione 0.000
Quercetin 0.000
Temozolomide 0.000
LIN 0.000
AICAR 0.000
Carvacrol 0.000
more...