Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:2.7.11.2 (PDK1)
 2,238 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds) .

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Human Gene/Protein
aldose reductase-related protein 13.8
alcohol dehydrogenase, iron containing, 1 13.8
pyruvate dehydrogenase kinase 13.8
OXCT protein 13.8
SRM160 13.8
Ankyrin repeat domain-containing protein 22 13.8
CRHSP24 13.8
PDK1 13.8
branched chain alpha-ketoacid dehydrogenase kinase 13.8
SYT16 13.8
SGK494 13.8
PDK2 13.8
PDK3 13.8
acyl-CoA synthetase short-chain family member 1 13.8
PDK4 13.8
STK1 13.8
actinin, alpha 2 13.8
PDK 13.6
stk2 13.2
PDK4 protein 13.0
PDP2 12.9
CORO2A 12.8
TBC1D30 12.8
ATP1G1 12.8
CSRNP3 12.8
PCYT1B 12.8
epithelial protein lost in neoplasm beta 12.8
phosphoinositide-3-kinase, catalytic, beta polypeptide 12.8
PDHK2 12.6
PDK1 protein 12.4
STK2 12.3
BRP44 12.2
stem cell tyrosine kinase 1 12.2
PANK4 12.2
PLEKHG4B 12.2
CRIK 12.0
BRP44L 11.8
NEDL2 11.8
tolloid-like protein 11.8
mitochondrial fission regulator 1 11.8
VPP1 11.5
INPP4B protein 11.5
apoptosis facilitator 11.5
PHLPPL 11.5
THBS1 protein 11.5
Pak-2 11.5
ZNF367 11.5
pyruvate dehydrogenase alpha subunit 11.5
NFKBIL2 11.5
bpoz 11.5
ZBTB2 11.3
SGK3 11.3
hMAP126 11.2
FRMD8 11.2
GNGT2 11.2
PLXDC2 11.2
FASTK 11.2
CHPPR 11.2
DAPL1 11.2
C1QTNF3 11.2
CSNK1G1 11.2
OSBPL3 11.2
RPS6KB2 11.1
cytokine-independent survival kinase 11.1
MYO1B 11.1
GRAP 11.1
PRK2 11.0
PDPK1 11.0
HIST1H2AC 11.0
ACN9 11.0
BTNL9 11.0
SYT5 11.0
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 11.0
ACSS1 11.0
TMEM129 11.0
ZPR9 11.0
KIAA1324 11.0
PFKFB4 10.9
COX4I2 10.9
3-phosphoinositide-dependent protein kinase 1 10.8
ADHFE1 10.8
PKB beta 10.8
RPS6KA2 10.8
CRIP2 10.8
CDC2L5 10.8
TARSH 10.8
tenascin XB 10.8
AGXT2L1 10.8
OXCT 10.8
MOGAT2 10.8
PDHC 10.8
PDH 10.7
pyruvate dehydrogenase complex 10.7
pyruvate dehydrogenase kinase 4 10.7
MUSTN1 10.6
ORP9 10.6
carboxypeptidase Z 10.6
LPGAT1 10.6
CALML3 10.6
EIF4H 10.6
SGK 10.6
Pyruvate dehydrogenase 10.5
BNIP2 10.5
MKNK1 10.5
TBCK 10.5
ABLIM 10.5
RBPMS2 10.5
serum/glucocorticoid regulated kinase 10.5
BMCC1 10.5
OTUD1 10.5
TSPEAR 10.5
TNFAIP8L3 10.5
nuclear factor of kappa light chain gene 10.5
STK3 10.4
CTMP 10.4
GPR176 10.3
EIF3C 10.3
RAB35 10.3
PIPPin 10.3
Orc4p 10.3
SGK2 10.3
pyruvate dehydrogenase 10.3
eukaryotic translation elongation factor 1 alpha 10.2
FRS2beta 10.2
ENTPD5 10.2
GPR19 10.2
CAMKK 10.2
DAGLA 10.2
ANKRD2 10.2
NEK3 10.2
Raftlin 10.2
DACH2 10.1
NEDL1 10.1
v-myc myelocytomatosis viral oncogene homolog 10.1
BCKDK 10.1
lactate dehydrogenase A 10.0
PRK1 10.0
LDHA 10.0
G-protein coupled receptor protein 10.0
MYOF 10.0
CLC1 10.0
hnRNP-R 10.0
Max-like protein X 10.0
CBFA2T1 10.0
NR1D2 10.0
SGK1 10.0
CTSZ 9.9
PHK 9.9
PTPN4 9.9
DECR1 9.9
protein kinase N1 9.9
TAF1B 9.9
SEC13 protein 9.9
IFRD1 9.9
PRKY 9.9
GSTZ1 9.9
PDHA1 9.8
PRUNE2 9.8
AP1S2 9.8
PKN3 9.8
more...
Disease
Hyper IgM syndrome 10.1
CEBPG 9.9
SHORT syndrome 9.8
Familial dilated cardiomyopathy 9.3
PDH deficiency 8.9
Neovascular age-related macular degeneration 8.8
Endometrioid carcinoma 8.6
Parvovirus infection 8.4
Late pregnancy 8.3
AUTS2 8.0
Calcium deficiency 7.9
PDP 7.6
PDC 7.6
ARTS 7.5
Transient cerebral ischemia 7.3
adult brain tumor 7.3
FED 7.1
recurrent NSCLC 7.1
hereditary sensory neuropathy 7.0
HRD 6.9
recurrent endometrial cancer 6.9
Peritoneum 6.7
Peritoneum 6.7
DMM 6.7
cancer angiogenesis 6.7
RP11 6.6
cancer regression 6.6
Ileum 6.6
Pleura 6.6
Pleura 6.5
PSN 6.5
Dengue hemorrhagic fever 6.4
Diabetic peripheral neuropathy 6.4
hemiparkinsonism 6.3
Postoperative cognitive dysfunction 6.3
SCD 6.2
Malignant glioma 6.0
MSF 6.0
Autosomal recessive polycystic kidney disease 5.8
PARK2 5.8
CAE 5.8
hypoglycemic coma 5.7
CMT1A 5.7
NCR 5.6
HTS 5.5
lactic acidosis 5.5
CYLD 5.5
Estrogen deficiency 5.4
OPA1 5.4
LIN 5.4
metastatic ovarian cancer 5.3
large cell carcinomas 5.3
Liver regeneration 5.3
FAS 5.1
CLS 5.1
Vesicular stomatitis 5.1
RBS 5.1
Cholangiocarcinoma 5.0
CEP 5.0
AGS 5.0
Pulmonary arterial hypertension 4.9
Glioblastoma 4.9
Cholangiocarcinoma 4.9
Peutz-Jeghers syndrome 4.9
Leigh syndrome 4.9
tuberous sclerosis 4.8
Diaphragm 4.8
proliferative vitreoretinopathy 4.7
TEC 4.7
heroin addiction 4.7
diabetic cardiomyopathy 4.7
eastern equine encephalitis 4.7
Neuroblastoma 4.7
Neuroblastoma 4.7
ovarian dysfunction 4.7
vascular obstruction 4.6
Charcot-Marie-Tooth disease 4.6
FBS 4.6
polycythemia 4.6
intestinal cancer 4.5
AS1 4.5
Hippel 4.5
HGF 4.5
Ovarian Cancer 4.5
glioblastoma 4.4
biliary tract cancer 4.4
inflammatory breast cancer 4.4
WSN 4.4
WSN 4.4
ganglioglioma 4.4
brain cancer 4.3
NPS 4.3
HBB 4.3
HBB 4.3
HBB 4.3
lipoatrophy 4.3
syndrome X 4.3
Worms 4.2
COL2A1 4.2
anal cancer 4.2
pulmonary insufficiency 4.2
lipid disorder 4.2
familial cancer 4.1
anal cancer 4.1
NLS 4.1
embryonal rhabdomyosarcoma 4.1
laryngeal squamous cell carcinoma 4.1
cowpox 4.1
hyperinsulinemia 4.1
hypernatremia 4.1
myxedema 4.1
ischemic optic neuropathy 4.1
primary pulmonary hypertension 4.1
NF2 4.1
tumorigenesis 4.1
NS3 4.0
tumor growth 4.0
pulmonic stenosis 4.0
dengue 4.0
Hypertrophic 4.0
nonmelanoma skin cancer 4.0
second cancer 4.0
oropharyngeal cancer 4.0
glioblastoma multiforme 4.0
right heart failure 3.9
mitochondrial disease 3.9
acute myocarditis 3.9
polycystic kidney 3.9
hyperthyroidism 3.9
trichotillomania 3.9
EMT 3.9
Tumour necrosis 3.9
Rhabdomyosarcoma 3.9
adenocarcinoma of the pancreas 3.8
TAM 3.8
non-small cell lung cancer 3.8
bone cancer 3.8
Friedreich's ataxia 3.8
hyperglycemia 3.8
cervicitis 3.8
myoma 3.8
protein deficiency 3.7
glucose intolerance 3.7
Japanese encephalitis 3.7
Osteosarcoma 3.7
Osteosarcoma 3.7
Pineal 3.7
tumor progression 3.7
LDLR 3.7
hereditary spherocytosis 3.7
limb-girdle muscular dystrophy 3.7
Blocking 3.6
PIN 3.6
gastrointestinal cancer 3.6
colon cancer 3.6
Colon cancer 3.6
MRS 3.6
acoustic neuroma 3.6
CHS 3.6
pancreatic cancer 3.6
more...
Symptom
starvation 5.3
eye pain 5.2
neurological disability 3.9
cachexia 3.7
decreased appetite 3.6
skin damage 3.2
exhaustion 3.1
dry eye 2.4
sore throat 2.4
hunger 2.3
HSA 2.2
acidity 2.2
polyuria 2.2
ophthalmoplegia 2.1
memory loss 2.0
pelvic pain 1.8
acute stress 1.6
numbness 1.5
hyperoxia 1.4
hypothermia 1.3
flushing 1.2
myalgia 1.1
anorexia 1.0
weakness 0.9
ataxia 0.8
fatigue 0.7
overweight 0.7
tremor 0.6
Ill 0.3
functional recovery 0.1
collapse -0.0
seizures -0.5
pain -1.6
anesthesia -2.0
headache -2.0
Drug
Diisopropylamine dichloroacetate 12.8
Sodium dichloroacetate 10.8
Hymenialdisine 10.5
Japanese encephalitis vaccine 7.7
Red ginseng 6.9
Etodolac 6.8
RAL 6.8
Triclosan 6.3
Flavopiridol 6.1
NOV 6.1
Ranolazine 5.8
Ranolazine 5.8
Zmax 5.8
Troglitazone 5.7
Rosiglitazone 5.7
CER 5.7
Exenatide 5.5
Cilostazol 5.1
AHF 4.9
KGF 4.9
NVP 4.9
ROS 4.6
AMC 4.6
NADH 4.5
Glycyrrhiza 4.3
Gleevec 4.3
OTC 4.3
Erlotinib 4.2
Amiloride 4.2
Fragment 4.2
Simvastatin 4.1
citric acid 4.0
Amiloride 4.0
Alanine 3.9
Itraconazole 3.9
TAK 3.8
Ketoconazole 3.8
OTC 3.7
Etoposide 3.6
Gefitinib 3.6
Azithromycin 3.5
Imatinib 3.5
Ouabain 3.5
Bortezomib 3.3
Sorafenib 3.2
Heme 3.2
GEO 3.2
Ginseng 3.1
Retinoic acid 3.1
Parkin 2.9
Parkin 2.9
Fructose 2.9
Portal 2.8
uPA 2.8
vitamin E 2.7
MAP 2.7
Herceptin 2.6
Glycerol 2.6
TMS 2.6
Nitric Oxide 2.5
Forskolin 2.4
ICI 2.4
ALA 2.3
Rituximab 2.3
lysine 2.2
ADM 2.2
Taxol 2.2
MRC 2.1
Kenyan 2.0
PCP 1.9
Glucagon 1.9
niacin 1.9
Asn 1.9
Angiotensin II 1.5
CaCl2 1.2
CaCl2 1.2
CaCl2 1.1
caffeine 1.0
Leaf 1.0
ascorbate 0.9
ROC 0.9
EE2 0.9
ABC 0.7
Monit 0.3
Gel -0.1
Nephron -0.3
Asthma -0.9
IFN-gamma -1.0
CSF -1.1
Cardiovasc -1.8
Enzyme
PDK1 13.8
pyruvate dehydrogenase phosphatase 12.4
STK2 10.9
BCKDH 10.9
pyruvate dehydrogenase 10.4
pyruvate dehydrogenase 10.4
pyruvate dehydrogenase 10.2
PDH 10.2
lipoate acetyltransferase 9.7
HK3 9.0
STK3 9.0
HK2 8.8
inositol polyphosphate 4-phosphatase 8.6
serum carnosinase 8.0
glycogenin 7.6
malonyl-CoA decarboxylase 7.6
myo-inositol oxygenase 7.5
protein L-isoaspartyl methyltransferase 7.5
CYP8B1 7.3
branched-chain alpha-keto acid dehydrogenase 7.2
phosphoinositide 3-kinase 7.1
2,4-dienoyl-CoA reductase 7.1
6-phosphofructo-2-kinase 7.0
rhomboid protease 7.0
inositol phosphatase 7.0
TOR 6.9
carnosinase 6.9
PHT 6.8
myo-inositol-1-phosphate synthase 6.8
phosphatidylinositol 3-kinase 6.8
CPT 6.7
STK 6.6
AMP-activated kinase 6.5
oxoglutarate dehydrogenase 6.5
ubiquinol-cytochrome c oxidoreductase 6.4
3'-phosphatase 6.4
AMPK 6.3
prolyl hydroxylase 6.3
GSK 6.3
hormone-sensitive lipase 6.2
succinyl-CoA synthetase 6.1
pyruvate carboxylase 6.0
AMP-activated protein kinase 6.0
3-hydroxyacyl-CoA dehydrogenase 6.0
glutathione synthetase 6.0
STK11 5.9
eEF2 kinase 5.9
acyl-CoA dehydrogenase 5.9
phosphomannomutase 5.9
acetyl-CoA carboxylase 5.9
CPT 5.9
peptide deformylase 5.9
fatty acid elongase 5.8
phosphofructokinase 5.8
phosphoribulokinase 5.8
pyruvate kinase 5.8
acyl-CoA dehydrogenase 5.8
TACE 5.7
CPT 5.7
AMPK 5.7
LPL 5.7
hexokinase 5.7
citrate lyase 5.7
PKG 5.7
pyruvate decarboxylase 5.7
MEK 5.6
phosphoenolpyruvate carboxykinase 5.6
focal adhesion kinase 5.6
protein kinase 5.5
glutaminase 5.5
alpha-ketoglutarate dehydrogenase 5.5
ACE 5.5
Omi/HtrA2 5.4
farnesyltransferase 5.4
protein kinase C 5.3
CEP 5.2
phosphoenolpyruvate carboxykinase 5.2
phosphoenolpyruvate carboxykinase 5.2
polo-like kinase 1 5.2
fructose 1,6-bisphosphatase 5.2
citrate synthase 5.1
IKK 5.1
glucokinase 5.1
calpain 3 5.0
PHD 5.0
protein phosphatase 2A 5.0
GRK2 5.0
phosphorylase kinase 5.0
ALDH 5.0
histone demethylase 4.9
HMG-CoA synthase 4.9
farnesyltransferase 4.8
glucose-6-phosphatase 4.8
isocitrate dehydrogenase 4.8
NADH-cytochrome b5 reductase 4.7
mitogen-activated protein kinase 4.7
CEP 4.7
glycine decarboxylase 4.6
isocitrate dehydrogenase 4.6
cysteine synthase 4.5
15-hydroxyprostaglandin dehydrogenase 4.5
TPP 4.5
calcineurin 4.4
ERK 4.4
arylalkylamine N-acetyltransferase 4.4
neutral sphingomyelinase 4.4
phosphatidylinositol 4-kinase 4.4
monoacylglycerol lipase 4.4
caspase-9 4.4
complex I 4.4
3-hydroxyacyl-CoA dehydrogenase 4.4
diaphorase 4.4
cdc2 4.4
TPP 4.3
glycerol kinase 4.3
aldehyde oxidase 4.3
phospholipase D 4.2
FAST 4.2
caspase-2 4.2
lactate dehydrogenase 4.2
caspase-2 4.1
BAT 4.1
phenol oxidase 4.1
diacylglycerol acyltransferase 4.0
MEKK1 3.9
glyceraldehyde-3-phosphate dehydrogenase 3.9
TdT 3.9
cystathionine beta-synthase 3.9
PARP 3.9
acyl-CoA oxidase 3.9
glucose-6-phosphate dehydrogenase 3.9
CYP7A1 3.9
diacylglycerol kinase 3.8
SCS 3.8
PTPase 3.8
ALA synthase 3.8
flavin-containing monooxygenase 3.7
3-hydroxy-3-methylglutaryl-CoA reductase 3.7
luciferase 3.7
fumarase 3.7
NADPH oxidase 3.7
caspase-8 3.6
caspase-3 3.6
lipoprotein lipase 3.6
histidine kinase 3.6
Thy1 3.6
arylsulfatase 3.5
DNA methyltransferase 3.5
glutathione S-transferase 3.5
glutamine synthetase 3.5
acyl-CoA synthetase 3.5
NADPH oxidase 3.5
transketolase 3.5
phosphoglucomutase 3.4
succinate dehydrogenase 3.4
phosphorylase 3.3
PGM 3.3
indoleamine 2,3-dioxygenase 3.3
gamma-glutamylcysteine synthetase 3.3
3-hydroxy-3-methylglutaryl coenzyme A reductase 3.3
more...
Compound
C9H10O3 11.8
GRP-1 10.6
Pachypodol 10.5
Dichloroacetate 10.4
Palmitoyl-L-carnitine 10.0
Pachymic acid 10.0
TCPA 9.9
S152 9.9
2-oxopropanamide 9.9
PDH 9.6
Deoxyelephantopin 9.6
2-methylpropanamide 9.5
difluoroacetic acid 9.3
Hymenialdisine 9.2
Hordenine 9.0
2,2-dichloroacetamide 8.9
Morusin 8.9
Phytosphingosine 8.8
WY-14,643 8.7
1H-pyrazolo[3,4-d]pyrimidine 8.4
Dibenzoylmethane 8.4
PDP 8.1
Anacardic acid 8.0
DX-52-1 7.8
Fusaric acid 7.7
Fusaric acid 7.7
Fusaric acid 7.7
acetyl-CoA 7.6
Asiaticoside 7.5
Succinyl-CoA 7.5
DCA 7.4
DCA 7.4
Pyruvate 7.4
Monocrotaline 7.3
LY 294002 7.2
Diacetoxyscirpenol 7.2
Acriflavine 7.2
Betulinic acid 7.2
dihydrolipoamide 7.1
NIX 7.0
bromoacetic acid 7.0
Phenethyl isothiocyanate 7.0
DBI 6.9
Betulin 6.9
Rottlerin 6.9
Kojic acid 6.9
PHT 6.8
Rottlerin 6.8
Rottlerin 6.8
Dihydromyricetin 6.8
2-Deoxy-D-glucose 6.6
TSC 6.5
Wortmannin 6.4
DEN 6.4
Isoliquiritigenin 6.4
Carnosine 6.4
KIV 6.3
AA861 6.3
Sesamin 6.3
octanoyl-CoA 6.3
TPCK 6.3
malonyl-CoA 6.2
Phosphatidylinositol 6.2
DGE 6.2
AGE 6.2
DGE 6.1
DGE 6.1
TPP 6.1
8-quinolinol 6.1
cis-vaccenic acid 6.0
Glyoxylate 6.0
DOCA 6.0
Salinomycin 6.0
Plumbagin 6.0
heptadecanoic acid 5.9
Celecoxib 5.9
(-)-Epigallocatechin 5.9
Baicalein 5.9
Caffeic acid phenethyl ester 5.9
CPT 5.9
ASK 5.9
2-oxobutyrate 5.9
heptadecanoic acid 5.9
3-hydroxy-2-butanone 5.9
MGBG 5.9
MGBG 5.9
Tetrandrine 5.8
Tetrandrine 5.8
Tetrandrine 5.8
Tetrandrine 5.8
Cinnamaldehyde 5.8
Digitonin 5.8
Shikonin 5.8
4-Hydroxynonenal 5.8
Rapamycin 5.8
BIP 5.7
CPT 5.7
TACE 5.7
threonine 5.7
TCH 5.7
merocyanine 540 5.6
PH2 5.6
Bacitracin 5.6
Oleanolic acid 5.5
TCA 5.5
TME 5.5
Leflunomide 5.5
Celastrol 5.4
alpha-ketoisocaproate 5.4
1H-pyrrole-2,5-dione 5.4
Pro-Gly 5.4
MEK 5.3
PAP 5.3
PAP 5.3
pentose 5.3
pentose 5.3
CoA 5.3
Carvacrol 5.3
Apigenin 5.2
pentose 5.2
Sulforaphane 5.2
Hearts 5.2
TBE 5.2
pentose 5.2
Temozolomide 5.1
AICAR 5.1
ITC 5.0
MAL 5.0
alloxan 5.0
MAOA 5.0
Flavin 5.0
Pima 4.9
3-hydroxyanthranilic acid 4.9
hydroxyglutarate 4.9
LIN 4.9
itaconic acid 4.9
Eugenol 4.9
Eugenol 4.8
Tanshinone 4.8
PPI 4.8
COX 4.8
MNU 4.8
Valine 4.8
PCN 4.7
Coenzyme A 4.7
Insulin 4.7
TEC 4.7
Staurosporine 4.7
Serine 4.7
2-oxoglutarate 4.6
decanoic acid 4.6
pentacene 4.6
Ferulic acid 4.6
Ferulic acid 4.6
Staurosporine 4.6
DPG 4.6
Isoform 4.6
OHB 4.6
NADH 4.5
quinazoline 4.5
more...