Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:2.7.11.17 (CaMKII)
4,029 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
CaMKII 2224
calmodulin 1445
CaM kinase II 507
Mol 388
Sep 295
ATP 255
CA1 213
CREB 185
calcineurin 180
phosphatase 176
NMDA receptor 175
PKA 168
PKC 166
threonine 149
AMP 139
cAMP-dependent protein kinase 139
ERK 123
protein phosphatase 116
calmodulin-dependent protein kinase IV 114
ERK1 113
insulin 110
MAPK 106
brain-derived neurotrophic factor 103
phospholamban 101
synapsin I 100
ATPase 98
p38 91
NR2B 79
AMP-activated protein kinase 75
calcium/calmodulin-dependent protein kinase II 73
endoplasmic reticulum 72
ryanodine receptor 68
PSD-95 67
glutamate receptor 65
myosin light chain kinase 64
histone 57
MEK 57
olfactory 56
phosphoprotein 54
phosphorylating 53
myosin 52
extracellular signal-regulated kinase 51
mitogen-activated protein 50
tyrosine kinase 50
c-fos 49
CA3 48
nitric oxide synthase 48
JNK 47
GABA 46
axonal 45
NR1 45
AMPK 44
RyR2 44
MAP kinase 43
tyrosine hydroxylase 42
PI3K 41
angiotensin II 41
STO 40
NR2A 40
neurogranin 40
PP1 39
polypeptide 39
PKG 39
phosphodiesterase 37
L-type calcium channel 37
synaptophysin 35
cytokine 34
Ang II 33
AIP 33
CaMKK 33
ionotropic 32
adenylate cyclase 32
cAMP response element-binding protein 32
PP2A 32
adenylyl cyclase 31
calcium channel 31
caspase-3 30
SDS 30
MEK1 30
phosphatidylinositol 3-kinase 30
more...
Disease
depression 125
Alzheimer's disease 114
heart failure 109
ischemia 106
cancer 90
tumor 55
diabetes 52
neuroblastoma 51
epilepsy 41
cerebral ischemia 37
hypertension 34
AIP 33
AIP 33
cognitive impairment 32
memory impairment 31
SDS 30
pertussis 29
myocardial infarction 26
obesity 24
schizophrenia 24
stroke 23
type 2 diabetes 22
LTD 20
glioma 20
Parkinson's disease 20
pheochromocytoma 19
autism 17
tetanus 17
Blocking 17
dementia 16
addiction 15
hyperglycemia 15
myocardial ischemia 14
heart disease 14
cardiomyopathy 14
NAME 14
atherosclerosis 14
prostate cancer 13
cardiovascular disease 12
tumorigenesis 12
metabolic syndrome 10
breast cancer 10
APC 10
hypothyroidism 10
leukemia 10
carcinoma 10
insulinoma 10
drug addiction 9
cold 9
chronic pain 9
dilated cardiomyopathy 9
mental illness 9
sepsis 8
hepatocellular carcinoma 8
plaque 8
OBX 8
posttraumatic stress disorder 8
sepsis 8
amyotrophic lateral sclerosis 7
mental retardation 7
GSH 7
status epilepticus 7
tumor growth 7
ventricular hypertrophy 7
cystic fibrosis 7
CAM 7
bipolar disorder 7
Rous sarcoma 7
mental retardation 7
fits 6
MCF 6
physical dependence 6
colorectal cancer 6
polycystic kidney 6
cholera 6
diabetic cardiomyopathy 6
coronary artery disease 5
MLC 5
chronic myeloid leukemia 5
lymphoma 5
more...
Symptom
pain 56
seizures 39
fatigue 9
memory loss 8
anesthesia 7
ataxia 7
exhaustion 6
hypothermia 6
collapse 5
vomiting 4
starvation 4
analgesia 4
rundown 4
acute stress 3
functional recovery 3
respiratory distress 3
bone pain 3
hypercapnia 3
despair 2
hypocapnia 2
insomnia 2
thinning 1
discomfort 1
acidity 1
Ill 1
Mobility Limitations 1
Cushingoid 1
eds 1
overweight 1
tremor 1
discomfort 1
fasciculation 1
cancer pain 1
headache 1
sleepiness 1
cerebellar ataxia 1
nausea 1
abnormal gait 1
dystonia 1
hyperoxia 1
Cushingoid 1
disturbed balance 1
Neuropathic pain 1
Drug
caffeine 32
ROS 22
MAP 22
Cardiovasc 18
lysine 18
Asn 11
Gel 11
Angiotensin II 11
K-252a 10
DFP 8
CAM 7
CaCl2 7
IL-2 7
CaCl2 7
CaCl2 7
CSF 6
Histamine 6
Forskolin 5
Glucagon 5
Ethanol 4
PCP 4
Trifluoperazine 4
Nitric Oxide 3
GHRP 3
ETA 3
vitamin E 3
Parkin 3
Monit 3
Retinoic acid 3
IFN-gamma 3
Parkin 3
Nephron 3
Leaf 3
Pronase 2
ENT 2
Dasatinib 2
Sorafenib 2
Escitalopram 2
MgSO4 2
Felodipine 2
Fragment 2
Ouabain 2
TAK 2
EE2 2
ascorbate 2
ABC 2
Flurothyl 2
ICI 2
Reserpine 2
p75 2
ALA 2
uPA 2
NVP 2
SMP 2
Tianeptine 2
Quisqualate 2
Propofol 2
Hyperforin 1
Ranolazine 1
Adenosine triphosphate 1
ETS 1
BH4 1
Allergen 1
Estrogens 1
RFP 1
CDP 1
Ranolazine 1
ZnCl2 1
EPI 1
Pimobendan 1
CG1 1
APD 1
Rolipram 1
ID2 1
L-tyrosine 1
NH3 1
Fluphenazine 1
Sulfadimethoxine 1
Phenytoin 1
Glycerol 1
more...
Enzyme
CaMKII 4029
protein kinase 1236
protein kinase C 540
mitogen-activated protein kinase 385
calcineurin 284
AMPK 244
ERK 149
AMP-activated protein kinase 114
ATPase 103
MEK 84
myosin light chain kinase 83
phospholipase C 79
polo-like kinase 1 76
AMPK 44
tyrosine hydroxylase 40
PKG 39
phosphodiesterase 37
luciferase 34
adenylate cyclase 33
focal adhesion kinase 32
phosphatidylinositol 3-kinase 30
GSK 28
caspase-3 25
protein phosphatase 2A 23
thrombin 22
NO synthase 22
MAP 22
superoxide dismutase 20
proteasome 20
NOS 19
NADPH oxidase 17
trypsin 16
phospholipase A2 16
NADPH oxidase 16
glutathione S-transferase 16
cdc2 15
guanylate cyclase 14
tryptophan hydroxylase 13
lactate dehydrogenase 13
alkaline phosphatase 13
phosphoinositide 3-kinase 12
acetyl-CoA carboxylase 11
CPT 11
catalase 11
reverse transcriptase 11
CPT 10
PDE 10
CPT 10
APC 10
beta-galactosidase 9
phosphorylase kinase 9
chymotrypsin 9
acetylcholinesterase 8
RNase 8
MEKK1 8
RNase 8
glyceraldehyde-3-phosphate dehydrogenase 8
glyceraldehyde-3-phosphate dehydrogenase 8
glyceraldehyde-3-phosphate dehydrogenase 8
glyceraldehyde-3-phosphate dehydrogenase 8
glyceraldehyde-3-phosphate dehydrogenase 8
phosphorylase 7
myosin ATPase 7
kinesin 7
choline acetyltransferase 6
collagenase 6
lipoxygenase 6
eEF2 kinase 6
pyruvate kinase 6
calcium pump 6
IKK 6
lipase 6
RNA polymerase 6
renin 5
phospholipase D 5
NSY 5
chloramphenicol acetyltransferase 5
PI-PLC 5
Mg2+-ATPase 5
guanylate kinase 4
more...
Compound
calcium 1772
Dec 308
threonine 285
cAMP 270
ATP 256
glutamate 239
serine 233
NMDA 186
AMPA 144
AMP 140
tyrosine 115
glucose 112
DNA 111
oxygen 110
phosphate 108
sodium 106
water 96
alanine 79
cGMP 71
potassium 65
nitric oxide 65
acetate 64
arginine 57
Cardiol 57
GABA 49
GABA 48
MEK 47
lysine 42
Mg2+ 41
Clin 39
Neuronal 35
5-HT 35
SDS 32
caffeine 32
sulfate 32
leucine 31
Asp 30
GTP 29
Phe 28
Ang II 27
COS 24
Glutamate 24
cysteine 23
MAP 22
PMA 22
PMA 22
salt 21
hydrogen 21
PEG 21
LTD 20
proline 20
ethanol 20
H2O2 20
DEAE 19
Insulin 19
ADP 18
ADP 18
2-hydroxyethyl 18
Triton X-100 18
methionine 18
2-hydroxyethyl 18
TNF 18
2-hydroxyethyl 18
2-hydroxyethyl 18
2-hydroxyethyl 18
2-hydroxyethyl 18
2-hydroxyethyl 18
ADP 18
2-hydroxyethyl 18
aspartic acid 17
retinoic acid 16
phosphoserine 16
Cereb 16
ACh 16
Gly 15
Angiotensin II 15
gamma-aminobutyric acid 15
propionic acid 14
5-methylisoxazole 14
propionic acid 14
more...