Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: EC:2.7.11.17 (
CaMKII
)
4,029
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
CaMKII
2224
calmodulin
1445
CaM kinase II
507
Mol
388
Sep
295
ATP
255
CA1
213
CREB
185
calcineurin
180
phosphatase
176
NMDA receptor
175
PKA
168
PKC
166
threonine
149
AMP
139
cAMP-dependent protein kinase
139
ERK
123
protein phosphatase
116
calmodulin-dependent protein kinase IV
114
ERK1
113
insulin
110
MAPK
106
brain-derived neurotrophic factor
103
phospholamban
101
synapsin I
100
ATPase
98
p38
91
NR2B
79
AMP-activated protein kinase
75
calcium/calmodulin-dependent protein kinase II
73
endoplasmic reticulum
72
ryanodine receptor
68
PSD-95
67
glutamate receptor
65
myosin light chain kinase
64
histone
57
MEK
57
olfactory
56
phosphoprotein
54
phosphorylating
53
myosin
52
extracellular signal-regulated kinase
51
mitogen-activated protein
50
tyrosine kinase
50
c-fos
49
CA3
48
nitric oxide synthase
48
JNK
47
GABA
46
axonal
45
NR1
45
AMPK
44
RyR2
44
MAP kinase
43
tyrosine hydroxylase
42
PI3K
41
angiotensin II
41
STO
40
NR2A
40
neurogranin
40
PP1
39
polypeptide
39
PKG
39
phosphodiesterase
37
L-type calcium channel
37
synaptophysin
35
cytokine
34
Ang II
33
AIP
33
CaMKK
33
ionotropic
32
adenylate cyclase
32
cAMP response element-binding protein
32
PP2A
32
adenylyl cyclase
31
calcium channel
31
caspase-3
30
SDS
30
MEK1
30
phosphatidylinositol 3-kinase
30
more...
Disease
depression
125
Alzheimer's disease
114
heart failure
109
ischemia
106
cancer
90
tumor
55
diabetes
52
neuroblastoma
51
epilepsy
41
cerebral ischemia
37
hypertension
34
AIP
33
AIP
33
cognitive impairment
32
memory impairment
31
SDS
30
pertussis
29
myocardial infarction
26
obesity
24
schizophrenia
24
stroke
23
type 2 diabetes
22
LTD
20
glioma
20
Parkinson's disease
20
pheochromocytoma
19
autism
17
tetanus
17
Blocking
17
dementia
16
addiction
15
hyperglycemia
15
myocardial ischemia
14
heart disease
14
cardiomyopathy
14
NAME
14
atherosclerosis
14
prostate cancer
13
cardiovascular disease
12
tumorigenesis
12
metabolic syndrome
10
breast cancer
10
APC
10
hypothyroidism
10
leukemia
10
carcinoma
10
insulinoma
10
drug addiction
9
cold
9
chronic pain
9
dilated cardiomyopathy
9
mental illness
9
sepsis
8
hepatocellular carcinoma
8
plaque
8
OBX
8
posttraumatic stress disorder
8
sepsis
8
amyotrophic lateral sclerosis
7
mental retardation
7
GSH
7
status epilepticus
7
tumor growth
7
ventricular hypertrophy
7
cystic fibrosis
7
CAM
7
bipolar disorder
7
Rous sarcoma
7
mental retardation
7
fits
6
MCF
6
physical dependence
6
colorectal cancer
6
polycystic kidney
6
cholera
6
diabetic cardiomyopathy
6
coronary artery disease
5
MLC
5
chronic myeloid leukemia
5
lymphoma
5
more...
Symptom
pain
56
seizures
39
fatigue
9
memory loss
8
anesthesia
7
ataxia
7
exhaustion
6
hypothermia
6
collapse
5
vomiting
4
starvation
4
analgesia
4
rundown
4
acute stress
3
functional recovery
3
respiratory distress
3
bone pain
3
hypercapnia
3
despair
2
hypocapnia
2
insomnia
2
thinning
1
discomfort
1
acidity
1
Ill
1
Mobility Limitations
1
Cushingoid
1
eds
1
overweight
1
tremor
1
discomfort
1
fasciculation
1
cancer pain
1
headache
1
sleepiness
1
cerebellar ataxia
1
nausea
1
abnormal gait
1
dystonia
1
hyperoxia
1
Cushingoid
1
disturbed balance
1
Neuropathic pain
1
Drug
caffeine
32
ROS
22
MAP
22
Cardiovasc
18
lysine
18
Asn
11
Gel
11
Angiotensin II
11
K-252a
10
DFP
8
CAM
7
CaCl2
7
IL-2
7
CaCl2
7
CaCl2
7
CSF
6
Histamine
6
Forskolin
5
Glucagon
5
Ethanol
4
PCP
4
Trifluoperazine
4
Nitric Oxide
3
GHRP
3
ETA
3
vitamin E
3
Parkin
3
Monit
3
Retinoic acid
3
IFN-gamma
3
Parkin
3
Nephron
3
Leaf
3
Pronase
2
ENT
2
Dasatinib
2
Sorafenib
2
Escitalopram
2
MgSO4
2
Felodipine
2
Fragment
2
Ouabain
2
TAK
2
EE2
2
ascorbate
2
ABC
2
Flurothyl
2
ICI
2
Reserpine
2
p75
2
ALA
2
uPA
2
NVP
2
SMP
2
Tianeptine
2
Quisqualate
2
Propofol
2
Hyperforin
1
Ranolazine
1
Adenosine triphosphate
1
ETS
1
BH4
1
Allergen
1
Estrogens
1
RFP
1
CDP
1
Ranolazine
1
ZnCl2
1
EPI
1
Pimobendan
1
CG1
1
APD
1
Rolipram
1
ID2
1
L-tyrosine
1
NH3
1
Fluphenazine
1
Sulfadimethoxine
1
Phenytoin
1
Glycerol
1
more...
Enzyme
CaMKII
4029
protein kinase
1236
protein kinase C
540
mitogen-activated protein kinase
385
calcineurin
284
AMPK
244
ERK
149
AMP-activated protein kinase
114
ATPase
103
MEK
84
myosin light chain kinase
83
phospholipase C
79
polo-like kinase 1
76
AMPK
44
tyrosine hydroxylase
40
PKG
39
phosphodiesterase
37
luciferase
34
adenylate cyclase
33
focal adhesion kinase
32
phosphatidylinositol 3-kinase
30
GSK
28
caspase-3
25
protein phosphatase 2A
23
thrombin
22
NO synthase
22
MAP
22
superoxide dismutase
20
proteasome
20
NOS
19
NADPH oxidase
17
trypsin
16
phospholipase A2
16
NADPH oxidase
16
glutathione S-transferase
16
cdc2
15
guanylate cyclase
14
tryptophan hydroxylase
13
lactate dehydrogenase
13
alkaline phosphatase
13
phosphoinositide 3-kinase
12
acetyl-CoA carboxylase
11
CPT
11
catalase
11
reverse transcriptase
11
CPT
10
PDE
10
CPT
10
APC
10
beta-galactosidase
9
phosphorylase kinase
9
chymotrypsin
9
acetylcholinesterase
8
RNase
8
MEKK1
8
RNase
8
glyceraldehyde-3-phosphate dehydrogenase
8
glyceraldehyde-3-phosphate dehydrogenase
8
glyceraldehyde-3-phosphate dehydrogenase
8
glyceraldehyde-3-phosphate dehydrogenase
8
glyceraldehyde-3-phosphate dehydrogenase
8
phosphorylase
7
myosin ATPase
7
kinesin
7
choline acetyltransferase
6
collagenase
6
lipoxygenase
6
eEF2 kinase
6
pyruvate kinase
6
calcium pump
6
IKK
6
lipase
6
RNA polymerase
6
renin
5
phospholipase D
5
NSY
5
chloramphenicol acetyltransferase
5
PI-PLC
5
Mg2+-ATPase
5
guanylate kinase
4
more...
Compound
calcium
1772
Dec
308
threonine
285
cAMP
270
ATP
256
glutamate
239
serine
233
NMDA
186
AMPA
144
AMP
140
tyrosine
115
glucose
112
DNA
111
oxygen
110
phosphate
108
sodium
106
water
96
alanine
79
cGMP
71
potassium
65
nitric oxide
65
acetate
64
arginine
57
Cardiol
57
GABA
49
GABA
48
MEK
47
lysine
42
Mg2+
41
Clin
39
Neuronal
35
5-HT
35
SDS
32
caffeine
32
sulfate
32
leucine
31
Asp
30
GTP
29
Phe
28
Ang II
27
COS
24
Glutamate
24
cysteine
23
MAP
22
PMA
22
PMA
22
salt
21
hydrogen
21
PEG
21
LTD
20
proline
20
ethanol
20
H2O2
20
DEAE
19
Insulin
19
ADP
18
ADP
18
2-hydroxyethyl
18
Triton X-100
18
methionine
18
2-hydroxyethyl
18
TNF
18
2-hydroxyethyl
18
2-hydroxyethyl
18
2-hydroxyethyl
18
2-hydroxyethyl
18
2-hydroxyethyl
18
ADP
18
2-hydroxyethyl
18
aspartic acid
17
retinoic acid
16
phosphoserine
16
Cereb
16
ACh
16
Gly
15
Angiotensin II
15
gamma-aminobutyric acid
15
propionic acid
14
5-methylisoxazole
14
propionic acid
14
more...