Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:2.7.11.17 (CaMKII)
 4,029 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
CaMKII 2224
calmodulin 1445
CaM kinase II 507
Mol 388
Sep 295
ATP 255
CA1 213
CREB 185
calcineurin 180
phosphatase 176
NMDA receptor 175
PKA 168
PKC 166
threonine 149
AMP 139
cAMP-dependent protein kinase 139
ERK 123
protein phosphatase 116
calmodulin-dependent protein kinase IV 114
ERK1 113
insulin 110
MAPK 106
brain-derived neurotrophic factor 103
phospholamban 101
synapsin I 100
ATPase 98
p38 91
NR2B 79
AMP-activated protein kinase 75
calcium/calmodulin-dependent protein kinase II 73
endoplasmic reticulum 72
ryanodine receptor 68
PSD-95 67
glutamate receptor 65
myosin light chain kinase 64
MEK 57
histone 57
olfactory 56
phosphoprotein 54
phosphorylating 53
myosin 52
extracellular signal-regulated kinase 51
tyrosine kinase 50
mitogen-activated protein 50
c-fos 49
CA3 48
nitric oxide synthase 48
JNK 47
GABA 46
NR1 45
axonal 45
AMPK 44
RyR2 44
MAP kinase 43
tyrosine hydroxylase 42
angiotensin II 41
PI3K 41
STO 40
NR2A 40
neurogranin 40
polypeptide 39
PKG 39
PP1 39
L-type calcium channel 37
phosphodiesterase 37
synaptophysin 35
cytokine 34
CaMKK 33
AIP 33
Ang II 33
PP2A 32
adenylate cyclase 32
ionotropic 32
cAMP response element-binding protein 32
calcium channel 31
adenylyl cyclase 31
CaM kinase I 30
phosphatidylinositol 3-kinase 30
caspase-3 30
SDS 30
MEK1 30
calpain 29
GTP 29
cardiac muscle 28
Bcl-2 28
LKB1 28
tau protein 28
Mem 28
myosin light chain 27
casein 27
neuronal nitric oxide synthase 26
protein kinase C inhibitor 26
cAMP response element binding protein 25
amyloid precursor protein 25
AKT 25
GSK 25
protein kinase inhibitor 25
caldesmon 25
PLC 25
mTOR 24
phospholipase 24
ERK2 24
Rho 23
fused 23
ROS 22
thrombin 22
metabotropic glutamate receptor 22
GAP-43 22
MAP 22
14-3-3 22
extracellular signal-regulated kinase 1 22
cAMP-response element 21
myelin basic protein 21
membrane-bound 21
HDAC4 21
nerve growth factor 20
glucagon 20
proteasome 20
alpha isoform 20
protein kinase B 19
Raf-1 19
bradykinin 19
c-Src 19
catenin 19
NMDA receptor subunit 19
serine/threonine kinase 19
CAMKII 19
microtubule-associated protein 2 19
glial fibrillary acidic protein 18
ubiquitin 18
HDAC5 18
ADP 18
cyclin 18
HEK 18
protein tyrosine kinase 18
TNF 18
AP-1 18
alpha, beta 18
p53 18
IL-6 17
histone deacetylase 17
superoxide dismutase 17
serine/threonine protein kinase 17
Ca2+-ATPase 17
vasopressin 17
atrial natriuretic peptide 16
LPS 16
GTPase 16
endothelin-1 16
tumor necrosis factor 16
Protein kinase 15
tropomyosin 15
lipopolysaccharide 15
epidermal growth factor 15
glycogen synthase 15
STAT3 14
MEF2 14
neurotrophic factor 14
calponin 14
thymus 14
more...
Disease
depression 125
Alzheimer's disease 114
heart failure 109
ischemia 106
cancer 90
tumor 55
diabetes 52
neuroblastoma 51
epilepsy 41
cerebral ischemia 37
hypertension 34
AIP 33
AIP 33
cognitive impairment 32
memory impairment 31
SDS 30
pertussis 29
myocardial infarction 26
schizophrenia 24
obesity 24
stroke 23
type 2 diabetes 22
Parkinson's disease 20
LTD 20
glioma 20
pheochromocytoma 19
tetanus 17
autism 17
Blocking 17
dementia 16
hyperglycemia 15
addiction 15
atherosclerosis 14
heart disease 14
cardiomyopathy 14
myocardial ischemia 14
NAME 14
prostate cancer 13
cardiovascular disease 12
tumorigenesis 12
metabolic syndrome 10
breast cancer 10
carcinoma 10
hypothyroidism 10
insulinoma 10
leukemia 10
APC 10
chronic pain 9
cold 9
dilated cardiomyopathy 9
mental illness 9
drug addiction 9
sepsis 8
plaque 8
posttraumatic stress disorder 8
sepsis 8
OBX 8
hepatocellular carcinoma 8
amyotrophic lateral sclerosis 7
GSH 7
mental retardation 7
status epilepticus 7
Rous sarcoma 7
bipolar disorder 7
ventricular hypertrophy 7
CAM 7
cystic fibrosis 7
mental retardation 7
tumor growth 7
colorectal cancer 6
fits 6
cholera 6
polycystic kidney 6
diabetic cardiomyopathy 6
physical dependence 6
MCF 6
ATM 5
chronic myeloid leukemia 5
diphtheria 5
worms 5
psychosis 5
sarcoma 5
lung carcinoma 5
Frey 5
Down syndrome 5
MLC 5
asthma 5
astrocytoma 5
lymphoma 5
coronary artery disease 5
lung cancer 4
immunodeficiency 4
osteoporosis 4
Angelman syndrome 4
congestive heart failure 4
diabetic nephropathy 4
myeloid leukemia 4
Huntington's disease 4
Evans 4
FAS 4
cocaine addiction 4
HIV 4
Recruitment 4
mole 4
carcinogenesis 4
squamous cell carcinoma 4
ADHD 4
glaucoma 4
PCP 4
mole 4
PND 4
Rett syndrome 3
liver cancer 3
migraine 3
colon cancer 3
drug abuse 3
neurological disease 3
infectious diseases 3
influenza 3
gastric cancer 3
chronic renal failure 3
alcoholism 3
aggression 3
IVA 3
hepatic encephalopathy 3
Hypertrophic 3
lissencephaly 3
pulmonary edema 3
mimicry 3
tumor progression 3
arthritis 3
affective disorder 3
adenoma 3
pulmonary hypertension 3
myopathy 3
rheumatoid arthritis 3
disinhibition 3
hyperinsulinemia 3
movement disorder 3
multiple sclerosis 3
major depressive disorder 3
metabolic disorder 3
glucose intolerance 3
brain edema 3
lung disease 3
endometrial cancer 3
vascular disease 3
familial adenomatous polyposis 3
glioblastoma 3
hypertrophic cardiomyopathy 3
uterus 3
erythroleukemia 2
drug withdrawal 2
Schistosoma mansoni 2
parkinsonism 2
fragile X syndrome 2
fear and anxiety 2
acute myocardial infarction 2
bone metastases 2
malaria 2
more...
Symptom
pain 56
seizures 39
fatigue 9
memory loss 8
anesthesia 7
ataxia 7
exhaustion 6
hypothermia 6
collapse 5
vomiting 4
starvation 4
analgesia 4
rundown 4
acute stress 3
functional recovery 3
respiratory distress 3
bone pain 3
hypercapnia 3
despair 2
hypocapnia 2
insomnia 2
thinning 1
discomfort 1
acidity 1
Ill 1
Mobility Limitations 1
Cushingoid 1
eds 1
overweight 1
tremor 1
discomfort 1
fasciculation 1
cancer pain 1
headache 1
sleepiness 1
cerebellar ataxia 1
nausea 1
abnormal gait 1
dystonia 1
hyperoxia 1
Cushingoid 1
disturbed balance 1
Neuropathic pain 1
Drug
caffeine 32
MAP 22
ROS 22
lysine 18
Cardiovasc 18
Angiotensin II 11
Asn 11
Gel 11
K-252a 10
DFP 8
CaCl2 7
CaCl2 7
IL-2 7
CAM 7
CaCl2 7
CSF 6
Histamine 6
Forskolin 5
Glucagon 5
PCP 4
Ethanol 4
Trifluoperazine 4
Nitric Oxide 3
GHRP 3
Parkin 3
Nephron 3
ETA 3
Leaf 3
Monit 3
Parkin 3
IFN-gamma 3
Retinoic acid 3
vitamin E 3
TAK 2
Dasatinib 2
p75 2
Sorafenib 2
Escitalopram 2
Tianeptine 2
SMP 2
Ouabain 2
EE2 2
ascorbate 2
ABC 2
uPA 2
MgSO4 2
Reserpine 2
ALA 2
ICI 2
Pronase 2
Flurothyl 2
NVP 2
Felodipine 2
Fragment 2
ENT 2
Quisqualate 2
Propofol 2
Adenosine triphosphate 1
Thioridazine 1
Emodin 1
ETS 1
Heme 1
BH4 1
TiO2 1
Allergen 1
Estrogens 1
RFP 1
CDP 1
Ranolazine 1
ZnCl2 1
EPI 1
Pimobendan 1
CG1 1
APD 1
Rolipram 1
ID2 1
L-tyrosine 1
NH3 1
Fluphenazine 1
Sulfadimethoxine 1
Phenytoin 1
Glycerol 1
SNL 1
ZnCl2 1
FAD 1
Valcyte 1
NADH 1
Photofrin 1
Rimonabant 1
TAT 1
MDM 1
Monensin 1
Menthol 1
FLP 1
Glide 1
Mutagen 1
Liraglutide 1
Simvastatin 1
Lubeluzole 1
Aluminum chloride 1
DHT 1
Luteinizing 1
IPD 1
Ranitidine 1
Lovastatin 1
Glutathione 1
AC2 1
Olomoucine 1
Emodin 1
Doxycycline 1
Growth hormone 1
Adriamycin 1
Butaprost 1
Itraconazole 1
TAC 1
Imatinib 1
G418 1
Gleevec 1
lactose 1
Growth hormone 1
Ranolazine 1
Taxol 1
Irinotecan 1
Asthma 1
-deoxyadenosine 1
DBS 1
Hyperforin 1
Kainic acid 1
DEX 1
Atosiban 1
Ganciclovir 1
ROC 1
Everolimus 1
DHT 1
Honey 1
PTH 1
Enzyme
CaMKII 4029
protein kinase 1236
protein kinase C 540
mitogen-activated protein kinase 385
calcineurin 284
AMPK 244
ERK 149
AMP-activated protein kinase 114
ATPase 103
MEK 84
myosin light chain kinase 83
phospholipase C 79
polo-like kinase 1 76
AMPK 44
tyrosine hydroxylase 40
PKG 39
phosphodiesterase 37
luciferase 34
adenylate cyclase 33
focal adhesion kinase 32
phosphatidylinositol 3-kinase 30
GSK 28
caspase-3 25
protein phosphatase 2A 23
MAP 22
NO synthase 22
thrombin 22
superoxide dismutase 20
proteasome 20
NOS 19
NADPH oxidase 17
trypsin 16
NADPH oxidase 16
glutathione S-transferase 16
phospholipase A2 16
cdc2 15
guanylate cyclase 14
alkaline phosphatase 13
tryptophan hydroxylase 13
lactate dehydrogenase 13
phosphoinositide 3-kinase 12
catalase 11
acetyl-CoA carboxylase 11
reverse transcriptase 11
CPT 11
CPT 10
APC 10
PDE 10
CPT 10
chymotrypsin 9
phosphorylase kinase 9
beta-galactosidase 9
acetylcholinesterase 8
glyceraldehyde-3-phosphate dehydrogenase 8
RNase 8
glyceraldehyde-3-phosphate dehydrogenase 8
MEKK1 8
glyceraldehyde-3-phosphate dehydrogenase 8
glyceraldehyde-3-phosphate dehydrogenase 8
RNase 8
glyceraldehyde-3-phosphate dehydrogenase 8
phosphorylase 7
kinesin 7
myosin ATPase 7
lipoxygenase 6
eEF2 kinase 6
RNA polymerase 6
pyruvate kinase 6
IKK 6
lipase 6
collagenase 6
choline acetyltransferase 6
calcium pump 6
NSY 5
renin 5
PI-PLC 5
phospholipase D 5
chloramphenicol acetyltransferase 5
Mg2+-ATPase 5
PCP 4
cytochrome oxidase 4
ACS 4
NQO1 4
lysozyme 4
ATP synthase 4
guanylate kinase 4
papain 3
mu-calpain 3
calpain 3 3
diacylglycerol kinase 3
SMP-I 3
heme oxygenase 3
glutathione peroxidase 3
aspartate aminotransferase 3
acid phosphatase 3
factor C 3
creatine kinase 3
TSA 3
histone acetyltransferase 3
caspase-9 3
rhodopsin kinase 2
CAD 2
CAD 2
GRK2 2
PARP 2
GRK5 2
CDP-diacylglycerol synthase 2
monoamine oxidase 2
cathepsin K 2
transcriptase 2
PDK1 2
CAD 2
caspase-8 2
adenosine kinase 2
AMP-activated kinase 2
xanthine oxidase 2
ornithine decarboxylase 2
6-phosphofructo-2-kinase 2
SMP 2
p80 2
type 1 protein phosphatase 2
12-lipoxygenase 2
histidine kinase 2
proton-translocating ATPase 2
urokinase-type plasminogen activator 2
pepsin 2
topoisomerase 2
sepiapterin reductase 2
hyaluronidase 2
phenylalanine hydroxylase 2
PAH 2
topoisomerase 2
DAT 2
dihydropteridine reductase 2
peroxidase 2
O-GlcNAc transferase 2
diacylglycerol acyltransferase 2
cholinesterase 2
aldolase 2
guanase 1
chondroitinase 1
paraoxonase 1
cathepsin B 1
glycerol kinase 1
aldehyde dehydrogenase 1
phosphatidate phosphatase 1
cathepsin L 1
aldehyde dehydrogenase 1
alpha-amylase 1
glycerophosphate acyltransferase 1
phosphoribulokinase 1
hypoxanthine-guanine phosphoribosyltransferase 1
glutamine synthetase 1
caspase-1 1
triphosphatase 1
m-calpain 1
acrosin 1
farnesyltransferase 1
pyruvate dehydrogenase 1
glucokinase 1
more...
Compound
calcium 1772
Dec 308
threonine 285
cAMP 270
ATP 256
glutamate 239
serine 233
NMDA 186
AMPA 144
AMP 140
tyrosine 115
glucose 112
DNA 111
oxygen 110
phosphate 108
sodium 106
water 96
alanine 79
cGMP 71
nitric oxide 65
potassium 65
acetate 64
arginine 57
Cardiol 57
GABA 49
GABA 48
MEK 47
lysine 42
Mg2+ 41
Clin 39
Neuronal 35
5-HT 35
sulfate 32
SDS 32
caffeine 32
leucine 31
Asp 30
GTP 29
Phe 28
Ang II 27
Glutamate 24
COS 24
cysteine 23
MAP 22
PMA 22
PMA 22
salt 21
PEG 21
hydrogen 21
proline 20
H2O2 20
LTD 20
ethanol 20
Insulin 19
DEAE 19
2-hydroxyethyl 18
TNF 18
ADP 18
2-hydroxyethyl 18
2-hydroxyethyl 18
2-hydroxyethyl 18
ADP 18
2-hydroxyethyl 18
methionine 18
ADP 18
2-hydroxyethyl 18
2-hydroxyethyl 18
Triton X-100 18
2-hydroxyethyl 18
aspartic acid 17
Cereb 16
retinoic acid 16
ACh 16
phosphoserine 16
Gly 15
Angiotensin II 15
gamma-aminobutyric acid 15
Nicotine 14
5-methylisoxazole 14
propionic acid 14
propionic acid 14
APV 14
tryptophan 13
PEG 13
manganese 13
aldosterone 13
zinc 12
FK506 12
Ryanodine 12
nitrogen 11
Nifedipine 11
NH2 11
Serine 11
KIV 10
His 10
Okadaic acid 10
CPT 10
2-methylpiperazine 10
Ile 10
CPT 10
NAD 10
glutamic acid 10
aspartic acid 10
Hearts 9
aspartic acid 9
Hearts 9
tryptophan 9
TRH 9
aspartic acid 9
MK801 9
isoquinoline 9
cadmium 8
CMK 8
Staurosporine 8
Thrombin 8
noradrenaline 8
NBQX 8
phosphocreatine 8
tryptophan 8
GSH 8
galactose 8
GSH 8
ammonium 8
Staurosporine 8
TPA 8
GM1 8
TPA 8
tryptophan 8
Tyrosine 8
CAM 7
Dopamine 7
CaCl2 7
bromide 7
NADPH 7
NADPH 7
Genistein 7
L-DOPA 7
GlcNAc 7
urea 7
Diisopropyl 7
isoxazole 7
NAD 6
Curcumin 6
Phorbol 6
glycerol 6
6-12 6
Melatonin 6
Histamine 6
Thapsigargin 6
nickel 6
Morphine 6
glutamine 6
Carbachol 6
UTP 6
acrylamide 6
MTT 6
adenylate 6
ADP-ribose 5
N-acetylcysteine 5
EDTA 5
more...