Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:2.7.11.13 (protein kinase C)
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Human Gene/Protein
transmembrane protein 40 9.3
STK24 9.3
FBXO10 protein 9.3
Alpha-tropomyosin 9.3
tumor necrosis factor type 1 receptor associated protein 9.3
CaCC2 9.3
NDUFS6 subunit 9.3
phorbolin 1 9.3
Sad1/unc-84 protein-like 1 9.3
FAM65A 9.3
P2Y purinoceptor 1 9.3
DXS1179E 9.3
bitter taste receptor T2R2 9.3
Adenylyl cyclase type II 9.3
phorbolin 2 9.3
ATPIF 9.3
V5-2 9.3
AKAP12 protein 9.3
hDGKzeta 9.3
HNRPH2 9.3
EGR alpha 9.3
PKCG 9.3
DNA replication licensing factor MCM5 9.3
axin interactor, dorsalization associated 9.3
collagen triple helix repeat-containing 9.3
vesicular nucleotide transporter SLC17A9 9.3
slingshot 2 9.3
NAG11 9.3
clone 112 9.3
SGK494 9.3
Bcd orf1 9.3
TWIK-originated similarity sequence 9.3
Protein kinase C eta 9.3
OK/SW-CL.16 9.3
GL014 9.3
KIAA1257 9.3
RINCK 9.3
PKC 9.1
PKC-L 9.0
PKC-alpha 8.9
MARCKS protein 8.8
PKC-beta 8.8
KCIP-1 8.8
PKCI 8.7
CD6 protein 8.6
CPI-17 8.5
protein kinase C inhibitor 8.5
MARCKS 8.5
PKC-gamma 8.4
C1q/TNF-related protein 8 8.3
RNF113B 8.3
Pyroglutamylated RFamide peptide 8.3
fibrous sheath protein of 95 kDa 8.3
unc-51-like kinase 4 8.3
V5-1 8.3
WW-domain binding protein 2 8.3
KIAA0846 8.3
RING finger protein 121 8.3
STX1A protein 8.3
PLCeta2 8.3
ZNFD 8.3
Transient receptor potential cation channel, subfamily V, member 1 8.3
ZNF354A 8.3
cerebral cavernous malformation 2 8.3
PKC2 8.3
inward rectifier K+ channel protein 8.3
Gz-selective GTPase-activating protein 8.3
ZNF99 8.3
F-box protein 10 8.3
PKCA 8.3
cytoplasmic linker associated protein 1 8.3
SHP2-interacting transmembrane adaptor protein 8.3
Josephin domain containing 1 8.3
Interferon-induced protein with tetratricopeptide repeats 2 8.3
FcGR 8.3
AMMECR1L 8.3
serine(threonine) protein kinase 8.3
HSD-3.1 8.3
opsin 4 8.3
Protein kinase D 8.3
more...
Disease
EVR2 9.3
Pulseless ventricular tachycardia 9.3
Deficiency of protein kinase 9.3
Calcium abnormality 9.3
EVR3 8.3
Atopic allergy 7.8
Moraxella catarrhalis infection 7.3
bronchial disorder 7.0
pediatric anaplastic astrocytoma 7.0
EVR1 6.8
INAD 6.7
congenital hyperbilirubinemia 6.6
Myxoid chondrosarcoma 6.5
Chronic respiratory acidosis 6.5
Bladder hypertrophy 6.5
TKC 6.3
CNC2 6.3
blood neoplasm 6.2
SAPD 6.2
histiocytic leukemia 6.2
AD9 6.0
Moraxella infection 6.0
Diabetic macroangiopathy 5.9
cerebral ischemia/hypoxia 5.9
KCS2 5.9
PDD 5.8
NEM1 5.8
DSCR 5.8
pertussis 5.7
urinary tract neoplasm 5.6
PNKD 5.5
Gastric infection 5.5
L.tropica 5.5
Psychological dependence 5.5
cystathioninuria 5.5
Necrobiosis lipoidica diabeticorum 5.4
Diabetic polyneuropathy 5.4
Bonnier 5.3
osteoblastic osteosarcoma 5.3
allergic edema 5.2
activation of latent virus 5.2
ICCA 5.2
LGMD1C 5.1
PGL3 5.1
EA4 5.0
Squamous cell carcinoma of the tongue 5.0
cartilage disorder 4.9
CACA 4.9
monocytic leukemia 4.9
endotheliosis 4.8
OBX 4.8
Diabetic maculopathy 4.8
Neutrophil dysfunction 4.8
Xeroderma 4.8
Diabetic neuropathy 4.7
SCA14 4.7
learning defect 4.7
Maternal diabetes mellitus 4.7
Neurocytomas 4.6
HCA1 4.6
brain anoxia 4.6
LTD 4.6
KAR 4.6
Mucolipidosis 4.5
CCM3 4.5
choline deficiency 4.5
Chloroma 4.4
Neurotrophic keratopathy 4.4
MLC 4.3
Feingold syndrome 4.3
skin tumor 4.3
Mauriac syndrome 4.3
amphetamine addiction 4.3
Diabetic macular edema 4.3
EL4 4.3
Chloracne 4.2
Bernhardt 4.2
Diabetic microangiopathy 4.2
Glanzmann 4.2
Scott syndrome 4.2
more...
Symptom
rundown 5.2
Mechanical pain 4.3
skin irritant 3.8
impaired motor coordination 3.8
Anoxia 3.4
Inflammatory pain 3.1
Hyperekplexia 2.9
Excitable 2.9
Crawling 2.8
stump pain 2.4
female puberty 2.4
fasciculation 2.2
Spots 2.1
autodigestion 2.0
scaly skin 1.9
skin damage 1.8
generalized pain 1.7
Scratch 1.7
Noise-induced hearing loss 1.7
functional recovery 1.7
Neuropathic pain 1.7
tonic seizure 1.6
disturbed balance 1.5
ACHE 1.5
orofacial pain 1.4
memory loss 1.3
athetosis 1.3
acute pain 1.3
acute stress 1.3
starvation 1.2
lassitude 1.2
Stepping 1.1
Excitability 1.0
bitter taste 0.9
incoordination 0.9
myalgia 0.8
eye pain 0.8
hyperoxia 0.7
muscle stiffness 0.7
rigors 0.7
analgesia 0.6
loss of balance 0.5
ataxia 0.5
hypercapnia 0.4
HSA 0.4
pain 0.3
twitching 0.3
cerebellar ataxia 0.3
Decreased activity 0.3
despair 0.3
menopausal symptoms 0.2
cachexia 0.2
spasm 0.2
neuralgia 0.2
Gastrointestinal symptoms 0.1
Fluctuation 0.1
hypothermia 0.0
asynergy -0.0
forgetfulness -0.1
right upper quadrant pain -0.1
thinning -0.1
collapse -0.1
seizures -0.3
general problem -0.4
DNA marker -0.5
exhaustion -0.6
splenomegaly -0.6
polyuria -0.7
cancer pain -0.7
bone pain -0.7
anorexia -0.7
eds -0.7
hot flashes -0.7
skin irritation -0.7
muscle rigidity -0.7
urinary frequency -0.8
abnormal gait -0.8
rhinorrhea -0.8
bradykinesia -0.9
dystonia -0.9
more...
Drug
Affinitak 9.3
Balanol 8.6
Safingol 8.5
Gypsum fibrosum 8.3
Xaliproden 8.3
7-Hydroxystaurosporine 8.2
Squalamine lactate 7.3
Petrin 7.3
K-252a 7.3
Lysophosphatidylglycerol 6.8
Azilect 6.6
Bromadryl 6.5
Indolidan 6.5
Gris-PEG 6.2
Forskolin 6.0
Emedastine difumarate 6.0
Hymenialdisine 6.0
Butaprost 6.0
Myotrophin 5.9
Benfotiamine 5.8
Loxoribine 5.8
Cnidii rhizoma 5.6
Ilmofosine 5.6
Stelazine 5.6
Elcatonin 5.6
Quisqualate 5.6
Phosphatidylserine 5.5
Olomoucine 5.5
Omacor 5.4
Octapressin 5.4
Carperitide 5.4
Midostaurin 5.4
1-Deoxymannojirimycin 5.3
Kifunensine 5.3
Epalrestat 5.3
Coix seed 5.2
Medalist 5.2
Amaryl 5.1
Angiotensin II 5.1
Rasagiline 5.1
TMX 5.1
Ganaxolone 5.0
Spiegel 4.9
GHRP 4.9
Nitecapone 4.9
Trifluoperazine 4.9
Purvalanol 4.8
Arachidonic Acid 4.7
Gliquidone 4.6
Blonanserin 4.6
4-Hydroxytamoxifen 4.6
Tenidap 4.6
Fidarestat 4.5
Sodium phenylbutyrate 4.5
Fidarestat 4.5
ETA 4.5
Adenosine Monophosphate 4.4
Batimastat 4.4
Batimastat 4.4
Dithranol 4.4
Acadesine 4.4
Concerta 4.3
Fluticasone furoate 4.2
Exelon 4.2
AC2 4.2
Flavopiridol 4.2
Fenoldopam 4.1
Ilomastat 4.1
Gastrozepin 4.1
Miltefosine 4.0
Gold sodium thiomalate 4.0
Propentofylline 4.0
Exelon 4.0
Palmitoyl 3.9
FSH-beta 3.9
Cicletanine 3.9
Sulprostone 3.9
FSH-beta 3.9
Histamine 3.9
Amiloride 3.9
more...
Enzyme
protein kinase C 9.3
1-alkyl-2-acetyl-sn-glycero-3-phosphate phosphohydrolase 9.3
alkyllyso-GP:acetyl-CoA acetyltransferase 7.8
diacylglycerol kinase 7.2
SMP-I 7.2
phospholipase D 7.1
phospholipase C 7.0
PI-PLC 6.7
myosin light chain kinase 6.7
CaMKII 6.4
peptidoglutaminase 6.3
PKG 6.3
protein kinase 6.2
STK13 6.2
Ins(1,4,5)P3 3-kinase 6.1
GRK5 6.0
ceramide cholinephosphotransferase 5.9
GRK2 5.9
pyroglutamyl peptidase II 5.8
PNAE 5.8
25-hydroxyvitamin D3 1alpha-hydroxylase 5.7
sphingosine kinase 5.7
phosphatidylinositol 3-kinase 5.7
MEK 5.6
PIP kinase 5.6
inositol 3-kinase 5.6
phosphatidylinositol phospholipase C 5.5
aspartate 1-decarboxylase 5.5
PAF acetyltransferase 5.5
2',3'-cyclic nucleotide phosphohydrolase 5.5
AMPK 5.5
STK4 5.5
protein phosphatase 2A 5.5
phosphoinositide 5-phosphatase 5.5
yapsin 1 5.4
NADPH oxidase 5.4
NADPH oxidase 5.4
PAF acetyltransferase 5.4
phospholipase A2 5.3
CMP-sialic acid:lactosylceramide sialyltransferase 5.3
PDK1 5.3
MHCK 5.2
calcineurin 5.2
mitogen-activated protein kinase 5.2
adenylate cyclase 5.2
rhodopsin kinase 5.2
phosphoinositide 3-kinase 5.2
alpha-1,6-mannosyltransferase 5.2
neutral sphingomyelinase 5.2
MEKK1 5.1
adamalysin 5.1
phosphatidylinositol 4-kinase 5.0
LTC4 synthase 5.0
phosphatidate phosphatase 4.9
eEF2 kinase 4.9
arachidonoyl-CoA synthetase 4.9
phosphorylase kinase 4.8
AMP-activated kinase 4.8
sphingomyelin synthase 4.8
phosphocholine cytidylyltransferase 4.8
duodenase 4.7
ceramide synthetase 4.7
PTPase 4.7
ceramidase 4.6
MGDG synthase 4.6
phenylacetone monooxygenase 4.6
p80 4.6
lysophosphatidylcholine acyltransferase 4.6
6-phosphofructo-2-kinase 4.5
12-lipoxygenase 4.5
KAR 4.5
phosphatidylinositol-4,5-bisphosphate 3-kinase 4.5
STK3 4.5
MAP 4.5
EC 3.2.1.58 4.5
aldose reductase 4.5
glycerol 3-phosphatase 4.4
GSase 4.4
lipoxygenase 4.4
CDP-diacylglycerol synthase 4.3
more...
Compound
Stearoylcarnitine 9.3
Distearin 9.3
8-hydroxy-1,3,6-naphthalenetrisulfonic acid 9.3
Ingenol 3,20-dibenzoate 9.3
2,2',4',5,5'-pentachloro-4-biphenylol 9.3
GF 109203X 9.2
2-methylpiperazine 8.9
Cystathionine ketimine 8.8
NAc-OCPC 8.8
Rottlerin 8.7
Chelerythrine 8.7
Chelerythrine 8.7
Rottlerin 8.6
Rottlerin 8.6
Phorbol 12-myristate 13-acetate 8.5
Phorbol-12,13-dibutyrate 8.5
Staurosporine 8.4
Phorbol 8.4
Staurosporine 8.4
Sangivamycin 8.2
Mezerein 8.2
C18H14N2O3 7.8
Isochamaejasmin 7.8
C17H14O5 7.8
Phorbol-12-myristate-13-acetate 7.7
DTBHQ 7.5
5-isoquinolinesulfonic acid 7.5
N-hydroxy-5-phenylpentanamide 7.5
methyl dihydrogen phosphate 7.5
PMA 7.5
Euxanthone 7.5
GW 7647 7.3
Daphnoretin 7.3
1-pyrrolidinecarbodithioic acid 7.3
2,2'-Dichlorobiphenyl 7.3
2-acetyl-1,3-cyclopentanedione 7.3
TPA 7.2
beta-tocopherol 7.2
DAG 7.2
TPA 7.0
3-methylisoquinoline 7.0
N-benzylguanidine 7.0
Daphnetoxin 7.0
CoQ4 7.0
1H-pyrrole-2,5-dione 7.0
PMA 6.9
LY 294002 6.8
Ingenol 6.8
Herbimycin 6.8
Tambulin 6.8
Jatrophone 6.8
13-Hydroxyoctadecadienoic acid 6.8
3,4,5-Trimethoxycinnamic acid 6.8
S 62 6.8
Calyculin A 6.7
8-Bromo-cyclic AMP 6.6
Triphenylethylene 6.6
2,5-pyrrolidinedione 6.6
Eudesmin 6.5
Dihydrofisetin 6.5
Temocaprilat 6.5
Okadaic acid 6.5
2-naphthalenesulfonamide 6.5
Sphingosine 6.5
Sphinganine 6.4
S152 6.4
Taurolithocholate 6.4
12(S)-HETE 6.4
alpha-Amyrin 6.3
1,2,4-trimethylcyclohexane 6.3
1,2,4-trimethylcyclohexane 6.3
NOCA 6.3
Resistomycin 6.3
Ammonium pyrrolidine dithiocarbamate 6.3
8-Bromoadenosine 6.3
8-Bromoadenosine 6.3
8-Bromoadenosine 6.3
8-Bromoadenosine 6.3
8-Bromoadenosine 6.3
8-Bromoadenosine 6.3
more...