Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:2.7.11.13 (protein kinase C)
49,245 document(s) hit in 31,850,051 MEDLINE articles (0.03 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
PKC 11365
Mol 4123
Sep 3589
ATP 2312
calmodulin 2287
insulin 2193
tyrosine kinase 2035
PKA 1595
AMP 1503
ERK1 1495
MAPK 1484
p38 1441
ERK 1359
threonine 1344
protein kinase C inhibitor 1220
cytokine 1165
TPA 1126
adenylate cyclase 1065
PKC-alpha 1019
phosphatase 996
angiotensin II 953
epidermal growth factor 919
MEK 914
thrombin 906
mitogen-activated protein 894
phosphatidylinositol 3-kinase 869
GTP 866
ATPase 820
extracellular signal-regulated kinase 818
phospholipase D 796
cAMP-dependent protein kinase 793
MAP kinase 785
PLC 783
c-fos 763
PI3K 697
collagen 690
phospholipase A2 671
tumor necrosis factor 666
Rho 659
JNK 650
adenylyl cyclase 642
AP-1 633
lipopolysaccharide 617
bradykinin 611
protein tyrosine kinase 559
caspase-3 555
nitric oxide synthase 546
endoplasmic reticulum 540
membrane-bound 538
Ang II 535
c-Jun 530
ADP 525
platelet-derived growth factor 513
protein phosphatase 512
cyclooxygenase 510
endothelin-1 494
vasopressin 475
alpha, beta 473
histone 468
phospholipase 452
TNF 444
fibronectin 420
CA1 409
polypeptide 404
myosin light chain 401
phosphoprotein 393
protein kinase inhibitor 393
calcineurin 392
RhoA 391
IL-2 390
p42 387
phosphodiesterase 382
epidermal growth factor receptor 378
PKC-beta 378
TNF-alpha 377
ras 377
PKC zeta 377
EGF receptor 376
EGF 374
myosin 369
more...
Disease
tumor 2938
cancer 2760
pertussis 1576
diabetes 1254
ischemia 915
leukemia 586
hypertension 577
Alzheimer's disease 546
neuroblastoma 531
carcinogenesis 509
hyperglycemia 504
breast cancer 484
cholera 475
atherosclerosis 451
depression 446
carcinoma 420
glioma 386
melanoma 353
hepatocellular carcinoma 341
MCF 329
HIV 325
SDS 287
tumorigenesis 286
type 2 diabetes 247
lymphoma 241
diabetic nephropathy 232
obesity 229
prostate cancer 228
tumor growth 223
heart failure 220
ATM 212
adenocarcinoma 204
tumor progression 192
colon cancer 190
immunodeficiency 186
stroke 182
Blocking 164
myocardial ischemia 155
asthma 152
pheochromocytoma 152
diabetic retinopathy 149
myocardial infarction 149
NAME 148
lung cancer 143
acute promyelocytic leukemia 140
cardiovascular disease 137
squamous cell carcinoma 132
metastases 130
astrocytoma 130
renal disease 127
PDD 125
sepsis 123
sepsis 122
GSH 120
Parkinson's disease 113
cerebral ischemia 109
glioblastoma 108
osteosarcoma 108
erythroleukemia 103
plaque 99
myeloid leukemia 98
Epstein 96
polycystic kidney 93
acute myeloid leukemia 93
rheumatoid arthritis 89
PDB 85
vascular disease 85
virus infection 83
lung carcinoma 82
bipolar disorder 81
cold 81
infectious diseases 80
colorectal cancer 80
cystic fibrosis 79
dementia 79
AIDS 79
gastric cancer 78
retinoblastoma 78
neuropathy 77
chronic lymphocytic leukemia 77
more...
Symptom
pain 515
seizures 104
starvation 89
functional recovery 67
analgesia 66
collapse 40
anesthesia 39
diarrhea 39
ataxia 35
rundown 29
hypothermia 27
myalgia 18
acute stress 17
hypercapnia 16
thinning 16
fatigue 16
acute pain 15
memory loss 14
exhaustion 14
spasm 13
respiratory distress 13
hyperoxia 13
anorexia 13
angina 12
weakness 12
vomiting 12
splenomegaly 10
cachexia 10
fasciculation 9
Anoxia 9
nausea 9
acidity 9
headache 8
skin damage 8
overweight 7
cerebellar ataxia 7
Neuropathic pain 7
erythema 7
dystonia 7
cough 7
HSA 6
chest pain 6
tremor 5
incoordination 5
flushing 4
twitching 4
discomfort 4
syncope 4
constipation 4
bitter taste 4
impaired motor coordination 4
discomfort 4
skin irritant 4
orofacial pain 4
ENT 3
cancer pain 3
muscle stiffness 3
paresthesia 3
myoclonus 3
bone pain 3
Spots 3
polyuria 3
despair 3
dyspnea 3
distraction 3
sleepiness 3
neuralgia 3
menopausal symptoms 3
abdominal pain 3
autodigestion 2
hepatosplenomegaly 2
numbness 2
neck pain 2
hepatomegaly 2
agitation 2
bradykinesia 2
dizziness 2
Scratch 2
rhinorrhea 2
rigors 2
more...
Drug
IL-2 393
MAP 297
Angiotensin II 267
Forskolin 263
ROS 247
Cardiovasc 231
IFN-gamma 231
Dermatol 213
lysine 205
caffeine 182
CSF 162
PTH 134
vitamin E 133
Histamine 127
Ethanol 125
Nephron 106
ETA 94
K-252a 83
CaCl2 80
ICI 80
CaCl2 80
CaCl2 80
Gel 78
Indomethacin 73
Asn 57
Ouabain 50
Phosphatidylserine 47
Retinoic acid 46
ascorbate 42
nitroglycerin 40
EE2 40
Glucagon 39
CAM 35
ADR 35
p75 35
Amiloride 34
Amiloride 34
Adriamycin 33
NADH 33
Vitamin E 33
IFN-beta 31
Heme 30
GHRP 26
Leaf 24
TAT 24
Taxol 23
CTX 23
Atropine 22
Growth hormone 22
Growth hormone 22
DNase I 22
uPA 21
Sodium nitroprusside 21
Trifluoperazine 20
Nitric Oxide 20
G-CSF 19
CCL 19
MRC 18
Activin 18
Imatinib 17
ABC 17
Alanine 17
ETS 16
ENT 16
EPA 15
Estrogens 14
GRF 13
Luteinizing 13
Quisqualate 13
Propofol 13
Monit 13
CDP 12
Vitamin A 12
Fructose 12
Arsenic trioxide 11
Gleevec 11
Gelatin 11
PCP 11
Portal 11
Adenosine triphosphate 11
more...
Enzyme
protein kinase C 49245
protein kinase 9214
mitogen-activated protein kinase 5579
phospholipase C 3614
ERK 1847
MEK 1390
adenylate cyclase 1115
calcineurin 999
phospholipase A2 901
thrombin 901
AMPK 884
phosphatidylinositol 3-kinase 872
ATPase 870
phospholipase D 796
focal adhesion kinase 772
NADPH oxidase 746
NADPH oxidase 680
CaMKII 540
luciferase 478
caspase-3 430
myosin light chain kinase 423
phosphodiesterase 384
phosphoinositide 3-kinase 333
PKG 310
catalase 301
superoxide dismutase 300
lipoxygenase 276
NO synthase 274
alkaline phosphatase 269
MAP 256
diacylglycerol kinase 228
trypsin 226
guanylate cyclase 214
protein phosphatase 2A 209
GSK 208
proteasome 199
glutathione S-transferase 197
AMP-activated protein kinase 195
cdc2 193
ornithine decarboxylase 189
collagenase 177
P-glycoprotein 174
renin 172
tyrosine hydroxylase 167
lactate dehydrogenase 166
urokinase-type plasminogen activator 138
PDK1 134
peroxidase 132
IKK 130
reverse transcriptase 129
PARP 122
chloramphenicol acetyltransferase 116
GRK5 113
aldose reductase 112
NOS 103
MEKK1 98
PI-PLC 94
lipase 91
lipoprotein lipase 87
AMPK 86
RNA polymerase 86
xanthine oxidase 85
acetylcholinesterase 84
topoisomerase 82
creatine kinase 81
caspase-8 80
glutathione peroxidase 78
GRK2 78
caspase-9 75
APC 69
topoisomerase 68
RNase 66
RNase 65
phosphorylase 62
acid phosphatase 60
sphingosine kinase 59
tissue plasminogen activator 55
transglutaminase 54
tyrosinase 52
MMP-3 52
more...
Compound
calcium 12612
acetate 9883
cAMP 3852
Dec 3745
DNA 3047
tyrosine 2958
serine 2549
ATP 2316
PMA 2213
PMA 2204
sodium 2161
glucose 2044
threonine 1849
oxygen 1795
phosphate 1713
AMP 1546
glutamate 1180
TPA 1126
TPA 1126
nitric oxide 1072
Phorbol 1059
glycerol 1050
Clin 927
alanine 887
GTP 871
cGMP 852
MEK 833
potassium 741
arginine 736
Phe 671
Staurosporine 599
Staurosporine 599
2-methylpiperazine 596
ADP 569
ethanol 548
water 538
ADP 528
ADP 527
leucine 481
cysteine 465
TNF 444
Insulin 427
sulfate 414
noradrenaline 397
Phorbol 12-myristate 13-acetate 378
hydrogen 375
GF 109203X 374
5-HT 365
GABA 361
GABA 355
lysine 348
Ang II 344
retinoic acid 344
H2O2 340
Cardiol 336
NMDA 329
methionine 329
COS 325
salt 311
PGE2 301
Angiotensin II 294
SDS 290
zinc 290
GDP 265
Forskolin 263
MAP 257
Mg2+ 256
DAD 251
DAG 251
NH2 240
AMPA 238
prostacyclin 231
Thrombin 230
aldosterone 222
Asp 219
NADPH 204
NADPH 203
PGE 199
galactose 197
bromide 197
more...