Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: EC:2.7.11.13 (
protein kinase C
)
49,245
document(s) hit in 31,850,051 MEDLINE articles (0.03 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
PKC
11365
Mol
4123
Sep
3589
ATP
2312
calmodulin
2287
insulin
2193
tyrosine kinase
2035
PKA
1595
AMP
1503
ERK1
1495
MAPK
1484
p38
1441
ERK
1359
threonine
1344
protein kinase C inhibitor
1220
cytokine
1165
TPA
1126
adenylate cyclase
1065
PKC-alpha
1019
phosphatase
996
angiotensin II
953
epidermal growth factor
919
MEK
914
thrombin
906
mitogen-activated protein
894
phosphatidylinositol 3-kinase
869
GTP
866
ATPase
820
extracellular signal-regulated kinase
818
phospholipase D
796
cAMP-dependent protein kinase
793
MAP kinase
785
PLC
783
c-fos
763
PI3K
697
collagen
690
phospholipase A2
671
tumor necrosis factor
666
Rho
659
JNK
650
more...
Disease
tumor
2938
cancer
2760
pertussis
1576
diabetes
1254
ischemia
915
leukemia
586
hypertension
577
Alzheimer's disease
546
neuroblastoma
531
carcinogenesis
509
hyperglycemia
504
breast cancer
484
cholera
475
atherosclerosis
451
depression
446
carcinoma
420
glioma
386
melanoma
353
hepatocellular carcinoma
341
MCF
329
HIV
325
SDS
287
tumorigenesis
286
type 2 diabetes
247
lymphoma
241
diabetic nephropathy
232
obesity
229
prostate cancer
228
tumor growth
223
heart failure
220
ATM
212
adenocarcinoma
204
tumor progression
192
colon cancer
190
immunodeficiency
186
stroke
182
Blocking
164
myocardial ischemia
155
pheochromocytoma
152
asthma
152
more...
Symptom
pain
515
seizures
104
starvation
89
functional recovery
67
analgesia
66
collapse
40
diarrhea
39
anesthesia
39
ataxia
35
rundown
29
hypothermia
27
myalgia
18
acute stress
17
hypercapnia
16
fatigue
16
thinning
16
acute pain
15
exhaustion
14
memory loss
14
hyperoxia
13
anorexia
13
respiratory distress
13
spasm
13
vomiting
12
angina
12
weakness
12
splenomegaly
10
cachexia
10
nausea
9
Anoxia
9
acidity
9
fasciculation
9
skin damage
8
headache
8
cerebellar ataxia
7
dystonia
7
overweight
7
erythema
7
cough
7
Neuropathic pain
7
more...
Drug
IL-2
393
MAP
297
Angiotensin II
267
Forskolin
263
ROS
247
Cardiovasc
231
IFN-gamma
231
Dermatol
213
lysine
205
caffeine
182
CSF
162
PTH
134
vitamin E
133
Histamine
127
Ethanol
125
Nephron
106
ETA
94
K-252a
83
CaCl2
80
CaCl2
80
CaCl2
80
ICI
80
Gel
78
Indomethacin
73
Asn
57
Ouabain
50
Phosphatidylserine
47
Retinoic acid
46
ascorbate
42
EE2
40
nitroglycerin
40
Glucagon
39
p75
35
CAM
35
ADR
35
Amiloride
34
Amiloride
34
NADH
33
Adriamycin
33
Vitamin E
33
more...
Enzyme
protein kinase C
49245
protein kinase
9214
mitogen-activated protein kinase
5579
phospholipase C
3614
ERK
1847
MEK
1390
adenylate cyclase
1115
calcineurin
999
thrombin
901
phospholipase A2
901
AMPK
884
phosphatidylinositol 3-kinase
872
ATPase
870
phospholipase D
796
focal adhesion kinase
772
NADPH oxidase
746
NADPH oxidase
680
CaMKII
540
luciferase
478
caspase-3
430
myosin light chain kinase
423
phosphodiesterase
384
phosphoinositide 3-kinase
333
PKG
310
catalase
301
superoxide dismutase
300
lipoxygenase
276
NO synthase
274
alkaline phosphatase
269
MAP
256
diacylglycerol kinase
228
trypsin
226
guanylate cyclase
214
protein phosphatase 2A
209
GSK
208
proteasome
199
glutathione S-transferase
197
AMP-activated protein kinase
195
cdc2
193
ornithine decarboxylase
189
more...
Compound
calcium
12612
acetate
9883
cAMP
3852
Dec
3745
DNA
3047
tyrosine
2958
serine
2549
ATP
2316
PMA
2213
PMA
2204
sodium
2161
glucose
2044
threonine
1849
oxygen
1795
phosphate
1713
AMP
1546
glutamate
1180
TPA
1126
TPA
1126
nitric oxide
1072
Phorbol
1059
glycerol
1050
Clin
927
alanine
887
GTP
871
cGMP
852
MEK
833
potassium
741
arginine
736
Phe
671
Staurosporine
599
Staurosporine
599
2-methylpiperazine
596
ADP
569
ethanol
548
water
538
ADP
528
ADP
527
leucine
481
cysteine
465
more...