Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:2.7.11.13 (protein kinase C)
49,245 document(s) hit in 31,850,051 MEDLINE articles (0.03 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
PKC 11365
Mol 4123
Sep 3589
ATP 2312
calmodulin 2287
insulin 2193
tyrosine kinase 2035
PKA 1595
AMP 1503
ERK1 1495
MAPK 1484
p38 1441
ERK 1359
threonine 1344
protein kinase C inhibitor 1220
cytokine 1165
TPA 1126
adenylate cyclase 1065
PKC-alpha 1019
phosphatase 996
angiotensin II 953
epidermal growth factor 919
MEK 914
thrombin 906
mitogen-activated protein 894
phosphatidylinositol 3-kinase 869
GTP 866
ATPase 820
extracellular signal-regulated kinase 818
phospholipase D 796
cAMP-dependent protein kinase 793
MAP kinase 785
PLC 783
c-fos 763
PI3K 697
collagen 690
phospholipase A2 671
tumor necrosis factor 666
Rho 659
JNK 650
more...
Disease
tumor 2938
cancer 2760
pertussis 1576
diabetes 1254
ischemia 915
leukemia 586
hypertension 577
Alzheimer's disease 546
neuroblastoma 531
carcinogenesis 509
hyperglycemia 504
breast cancer 484
cholera 475
atherosclerosis 451
depression 446
carcinoma 420
glioma 386
melanoma 353
hepatocellular carcinoma 341
MCF 329
HIV 325
SDS 287
tumorigenesis 286
type 2 diabetes 247
lymphoma 241
diabetic nephropathy 232
obesity 229
prostate cancer 228
tumor growth 223
heart failure 220
ATM 212
adenocarcinoma 204
tumor progression 192
colon cancer 190
immunodeficiency 186
stroke 182
Blocking 164
myocardial ischemia 155
pheochromocytoma 152
asthma 152
more...
Symptom
pain 515
seizures 104
starvation 89
functional recovery 67
analgesia 66
collapse 40
diarrhea 39
anesthesia 39
ataxia 35
rundown 29
hypothermia 27
myalgia 18
acute stress 17
hypercapnia 16
fatigue 16
thinning 16
acute pain 15
exhaustion 14
memory loss 14
hyperoxia 13
anorexia 13
respiratory distress 13
spasm 13
vomiting 12
angina 12
weakness 12
splenomegaly 10
cachexia 10
nausea 9
Anoxia 9
acidity 9
fasciculation 9
skin damage 8
headache 8
cerebellar ataxia 7
dystonia 7
overweight 7
erythema 7
cough 7
Neuropathic pain 7
more...
Drug
IL-2 393
MAP 297
Angiotensin II 267
Forskolin 263
ROS 247
Cardiovasc 231
IFN-gamma 231
Dermatol 213
lysine 205
caffeine 182
CSF 162
PTH 134
vitamin E 133
Histamine 127
Ethanol 125
Nephron 106
ETA 94
K-252a 83
CaCl2 80
CaCl2 80
CaCl2 80
ICI 80
Gel 78
Indomethacin 73
Asn 57
Ouabain 50
Phosphatidylserine 47
Retinoic acid 46
ascorbate 42
EE2 40
nitroglycerin 40
Glucagon 39
p75 35
CAM 35
ADR 35
Amiloride 34
Amiloride 34
NADH 33
Adriamycin 33
Vitamin E 33
more...
Enzyme
protein kinase C 49245
protein kinase 9214
mitogen-activated protein kinase 5579
phospholipase C 3614
ERK 1847
MEK 1390
adenylate cyclase 1115
calcineurin 999
thrombin 901
phospholipase A2 901
AMPK 884
phosphatidylinositol 3-kinase 872
ATPase 870
phospholipase D 796
focal adhesion kinase 772
NADPH oxidase 746
NADPH oxidase 680
CaMKII 540
luciferase 478
caspase-3 430
myosin light chain kinase 423
phosphodiesterase 384
phosphoinositide 3-kinase 333
PKG 310
catalase 301
superoxide dismutase 300
lipoxygenase 276
NO synthase 274
alkaline phosphatase 269
MAP 256
diacylglycerol kinase 228
trypsin 226
guanylate cyclase 214
protein phosphatase 2A 209
GSK 208
proteasome 199
glutathione S-transferase 197
AMP-activated protein kinase 195
cdc2 193
ornithine decarboxylase 189
more...
Compound
calcium 12612
acetate 9883
cAMP 3852
Dec 3745
DNA 3047
tyrosine 2958
serine 2549
ATP 2316
PMA 2213
PMA 2204
sodium 2161
glucose 2044
threonine 1849
oxygen 1795
phosphate 1713
AMP 1546
glutamate 1180
TPA 1126
TPA 1126
nitric oxide 1072
Phorbol 1059
glycerol 1050
Clin 927
alanine 887
GTP 871
cGMP 852
MEK 833
potassium 741
arginine 736
Phe 671
Staurosporine 599
Staurosporine 599
2-methylpiperazine 596
ADP 569
ethanol 548
water 538
ADP 528
ADP 527
leucine 481
cysteine 465
more...