Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: EC:2.7.11.13 (
protein kinase C
)
49,245
document(s) hit in 31,850,051 MEDLINE articles (0.03 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
PKC
11365
Mol
4123
Sep
3589
ATP
2312
calmodulin
2287
insulin
2193
tyrosine kinase
2035
PKA
1595
AMP
1503
ERK1
1495
MAPK
1484
p38
1441
ERK
1359
threonine
1344
protein kinase C inhibitor
1220
cytokine
1165
TPA
1126
adenylate cyclase
1065
PKC-alpha
1019
phosphatase
996
more...
Disease
tumor
2938
cancer
2760
pertussis
1576
diabetes
1254
ischemia
915
leukemia
586
hypertension
577
Alzheimer's disease
546
neuroblastoma
531
carcinogenesis
509
hyperglycemia
504
breast cancer
484
cholera
475
atherosclerosis
451
depression
446
carcinoma
420
glioma
386
melanoma
353
hepatocellular carcinoma
341
MCF
329
more...
Symptom
pain
515
seizures
104
starvation
89
functional recovery
67
analgesia
66
collapse
40
diarrhea
39
anesthesia
39
ataxia
35
rundown
29
hypothermia
27
myalgia
18
acute stress
17
thinning
16
hypercapnia
16
fatigue
16
acute pain
15
exhaustion
14
memory loss
14
anorexia
13
more...
Drug
IL-2
393
MAP
297
Angiotensin II
267
Forskolin
263
ROS
247
Cardiovasc
231
IFN-gamma
231
Dermatol
213
lysine
205
caffeine
182
CSF
162
PTH
134
vitamin E
133
Histamine
127
Ethanol
125
Nephron
106
ETA
94
K-252a
83
CaCl2
80
ICI
80
more...
Enzyme
protein kinase C
49245
protein kinase
9214
mitogen-activated protein kinase
5579
phospholipase C
3614
ERK
1847
MEK
1390
adenylate cyclase
1115
calcineurin
999
phospholipase A2
901
thrombin
901
AMPK
884
phosphatidylinositol 3-kinase
872
ATPase
870
phospholipase D
796
focal adhesion kinase
772
NADPH oxidase
746
NADPH oxidase
680
CaMKII
540
luciferase
478
caspase-3
430
more...
Compound
calcium
12612
acetate
9883
cAMP
3852
Dec
3745
DNA
3047
tyrosine
2958
serine
2549
ATP
2316
PMA
2213
PMA
2204
sodium
2161
glucose
2044
threonine
1849
oxygen
1795
phosphate
1713
AMP
1546
glutamate
1180
TPA
1126
TPA
1126
nitric oxide
1072
more...