Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: EC:2.7.11.13 (
protein kinase C
)
49,245
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
Rat brain protein kinase C (
PKC
) isozymes I, II and III were stimulated by fatty acids in the absence and presence of calcium.
Ethyl oleate
, which by itself has no effect on
PKC
activity, had a potentiating effect on fatty acid-induced activation of all 3 isozymes. Potentiation was observed predominantly in the presence of calcium. Interaction of ethyl oleate with a signalling mechanism involving
PKC
may underlie the cognitive disturbances noted after alcohol consumption.
...
PMID:Response of brain protein kinase C isozymes to ethyl oleate, an alcohol metabolite. 193 86
