Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:2.7.11.12 (PKG)
 2,515 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
SGK494 13.6
CGKII 13.6
PRKG1B 13.6
PKG 13.6
GKAP42 12.9
TRIM39R 12.6
CT42 12.6
SLC8A1 protein 12.6
PKG1 12.4
G-substrate 12.4
IRAG 12.3
G-septin 12.2
cGKI 12.2
poliovirus receptor-related 3 12.0
eukaryotic translation initiation factor 4E nuclear import factor 1 12.0
cGMP-stimulated phosphodiesterase 2 12.0
CRIK 11.8
Regulator of G-protein signaling 18 11.6
synaptonemal complex protein 2 11.6
PLEKHA2 11.3
mitogen-activated protein kinase kinase kinase kinase 3 11.3
serine/threonine kinase 38 11.3
M-RIP 11.3
PRKG1 11.2
SNAP1 11.0
Rap1GAP2 11.0
PDED 11.0
myosin phosphatase regulatory subunit 10.8
RAP2C 10.8
PIG-F 10.8
PLEKHB1 10.8
SPHKAP 10.8
phosphodiesterase 9A 10.8
vasodilator-stimulated phosphoprotein 10.8
ENOPH1 10.6
cGKII 10.6
SLC8A2 10.6
PARD6G 10.6
PNPLA7 10.6
phosphodiesterase 5A 10.5
p116Rip 10.5
POTEE 10.5
GMPS 10.3
SLC9A2 10.3
smoothelin-like 1 10.2
soluble guanylyl cyclase 10.2
cysteine-rich protein 2 10.2
TSNAX 10.2
MDFI 10.2
GPR176 10.2
MRVI1 10.2
natriuretic peptide receptor B 10.1
RASGEF1B 10.0
GA protein 10.0
PPP1R9B 9.9
GUCY1B3 9.9
Nucleobindin 2 9.9
Fibroblast growth factor 5 9.9
rd2 9.9
guanylyl cyclase 9.8
phosphoprotein phosphatase-1 9.8
TRIM39 9.8
adenylyl cyclase type V 9.8
ARPP 9.8
natriuretic peptide clearance receptor 9.8
PDE5A 9.7
PRKY 9.7
PNPLA8 9.7
DECR1 9.7
cAMP-dependent protein kinase catalytic subunit 9.7
PDE5 9.7
transient receptor potential channel 3 9.6
SRRM2 9.6
KEPI 9.6
telokin 9.6
PDE1A 9.5
PDE2 9.4
DG2 9.4
GNG11 9.4
putative anion transporter 9.4
more...
Disease
Multiple carboxylase deficiency 10.8
CNC2 10.6
FHM2 8.8
Spring viremia of carp 7.9
PDE 7.8
Waterhouse-Friderichsen syndrome 7.6
Renal interstitial fibrosis 7.5
ischemic ulcer 7.3
AD8 7.3
hypertensive cardiomyopathy 7.1
MBS 6.7
NAME 6.6
Diabetes and Pregnancy 6.3
CHH 6.2
LTD 6.2
achromatopsia 6.2
PAPA 6.0
learning disorder 6.0
Diaz 5.9
Vidal 5.9
delayed speech 5.8
MLC 5.7
erectile dysfunction 5.5
AGS 5.5
SMC 5.5
memory disorder 5.4
RGS 5.4
Vascular lesions 5.4
anxiety state 5.2
LIN 5.2
coccidiosis 5.2
anal fissure 5.1
uterine leiomyosarcoma 5.0
hearing disorder 5.0
Renal fibrosis 5.0
Bardet-Biedl syndrome 4.9
platelet disorder 4.9
Hypertrophic 4.8
CSE 4.8
Pulmonary arterial hypertension 4.8
AS1 4.8
PDD 4.7
HRS 4.7
SM1 4.7
Frey 4.6
meningococcal infection 4.5
hereditary spherocytosis 4.5
hemiplegic migraine 4.5
tularemia 4.4
MLS 4.4
Luminal 4.4
opisthorchiasis 4.4
Wilson's disease 4.4
Endothelial dysfunction 4.3
PIN 4.3
postmenopausal bone loss 4.2
adenocarcinoma of the colon 4.2
LCD 4.2
pertussis 4.1
Hepatotoxicity 4.1
pulmonary hypertension 4.0
paroxysmal nocturnal hemoglobinuria 4.0
FAS 4.0
CLN3 4.0
Harada 3.9
hypertensive heart disease 3.9
antidiuresis 3.9
acute monocytic leukemia 3.9
HCI 3.8
ICS 3.7
PTP 3.7
prediabetes 3.7
bone cancer 3.6
Adenovirus 3.6
GCE 3.6
PIN 3.5
cocaine addiction 3.5
SCD 3.5
heart failure 3.5
intermittent claudication 3.4
more...
Symptom
Lower urinary tract symptoms 6.1
Noise-induced hearing loss 6.0
rundown 4.7
clumsiness 4.5
Anoxia 4.5
orofacial pain 3.7
acute pain 3.3
bradykinesia 2.4
angina 1.8
cerebellar ataxia 1.8
memory loss 1.8
spasm 1.8
hypercapnia 1.7
hemiplegia 1.7
dystonia 1.6
myoclonus 1.6
functional recovery 1.5
collapse 1.4
cachexia 1.2
hepatomegaly 1.1
hypotonia 1.1
pain 1.0
arthralgia 0.8
diarrhea 0.8
nausea and vomiting 0.4
splenomegaly 0.4
constipation 0.3
anorexia -0.1
respiratory distress -0.6
cough -0.9
starvation -1.0
overweight -1.1
analgesia -1.2
vomiting -1.3
seizures -1.7
fatigue -2.0
anesthesia -2.1
Drug
Primacor 12.0
Primacor 11.3
Indolidan 10.8
Carperitide 10.7
Levitra 9.4
Levitra 9.0
Alarin 8.8
Vardenafil 8.2
Darifenacin 8.1
Sodium nitroprusside 7.6
Cicletanine 7.2
Glybenclamide 7.0
Viagra 6.8
Rhubarb 6.6
Nitric Oxide 6.5
Rolipram 6.5
Viagra 6.4
Vinpocetine 6.4
Trental 6.3
Forskolin 6.3
BOTOX 6.2
K-252a 6.2
CIA 6.0
Cilostazol 5.9
Iloprost 5.6
Methylene blue 5.3
GEO 5.0
Bosentan 4.9
Bosentan 4.9
Liraglutide 4.9
Angiotensin II 4.8
Papaverine 4.8
nitroglycerin 4.7
Donepezil 4.5
Phosphatidylserine 4.2
Heme 4.0
Ouabain 3.9
BoNT/A 3.9
APD 3.8
Adenosine triphosphate 3.8
Photofrin 3.8
TAK 3.7
Diphenhydramine 3.6
Etoposide 3.5
caffeine 3.3
Arsenic trioxide 3.3
ROS 3.3
Honey 3.3
Alliance 3.2
IL-1ra 3.2
FeCl3 3.2
Vitamin K 3.2
Glycyrrhiza 3.2
TAC 3.0
MAP 2.9
TTC 2.8
Glucagon 2.8
Theophylline 2.6
-deoxyadenosine 2.6
Indomethacin 2.6
CaCl2 2.6
CaCl2 2.6
EPI 2.6
CaCl2 2.5
Estrogens 2.5
Captopril 2.5
Glycerol 2.5
L-tyrosine 2.4
Silica 2.4
TAT 2.4
ICI 2.2
Alanine 2.2
Asn 2.1
Atropine 1.9
EE2 1.7
Monit 1.5
Nephron 1.5
Ethanol 1.4
lysine 1.2
Glutathione 1.2
more...
Enzyme
PKG 13.6
guanylate cyclase 9.4
AMPK 8.3
protein kinase 8.3
cGMP phosphodiesterase 7.8
PDE 7.6
myosin light chain kinase 7.4
phosphodiesterase 7.3
protein phosphatase 2A 7.2
NOS 7.1
CaMKII 6.9
NO synthase 6.8
CPT 6.7
sulfiredoxin 6.7
phosphorylase kinase 6.6
CPT 6.6
protein kinase C 6.3
type 1 protein phosphatase 6.3
CPT 6.2
phosphoribulokinase 6.2
PI-PLC 6.1
rhodopsin kinase 6.0
AMP-activated kinase 5.8
guanase 5.8
sphingomyelin synthase 5.7
3-mercaptopyruvate sulfurtransferase 5.7
PRPP synthetase 5.7
PHT 5.7
PDK1 5.7
CPL 5.6
ADPase 5.5
GRK5 5.5
GRK2 5.5
calcineurin 5.4
dimethylarginine dimethylaminohydrolase 5.4
MPP 5.3
6-phosphofructo-2-kinase 5.3
propionyl-CoA carboxylase 5.2
ADP-ribosyltransferase 5.2
mu-calpain 5.2
propionyl-CoA carboxylase 5.2
ADP-ribosyltransferase 5.2
hormone-sensitive lipase 5.1
guanylate kinase 5.1
AMPK 5.1
prostacyclin synthase 5.1
SNO 5.1
AGT 5.0
m-calpain 5.0
heme oxygenase 4.9
TSP-1 4.9
NAD glycohydrolase 4.9
phosphoglycerate kinase 4.9
sucrase-isomaltase 4.9
phosphatidylinositol 3-kinase 4.8
C3 convertase 4.8
caspase-6 4.7
prolidase 4.7
caspase-6 4.7
PTPase 4.6
N-acetylglucosaminyltransferase 4.6
apyrase 4.6
phospholipase C 4.6
mitogen-activated protein kinase 4.6
aromatic L-amino acid decarboxylase 4.6
CNPase 4.6
AMP-activated protein kinase 4.5
GSK 4.5
MEK 4.5
CDH 4.5
1-hydroxylase 4.5
5'-nucleotidase 4.3
factor C 4.3
adenylate cyclase 4.3
neutral sphingomyelinase 4.2
phosphoglucomutase 4.2
AMP deaminase 4.2
GCA 4.2
ornithine aminotransferase 4.1
aequorin 4.1
more...
Compound
D-NONOate 13.6
8-Bromoinosine 13.6
8-Br-cGMP 11.6
DT3 11.1
1-methylpiperidine 10.6
ethanimidamide 10.3
cGMP 9.9
Isopropylamine 9.8
p-Synephrine 9.7
4-methoxybenzenesulfonamide 9.5
C6H12O5 9.4
Sildenafil 8.7
1-methyl-1,2,3,6-tetrahydropyridine 8.7
DEA 8.7
DEA 8.7
DETA 8.6
DEA 8.6
Fostriecin 8.4
Malvidin 8.2
GMP 8.0
Ginsenoside Re 7.9
Cyclic ADP-ribose 7.7
Synephrine 7.5
Cinnamyl alcohol 7.5
GF 109203X 7.5
ITG 7.4
IAA-94 7.3
Sulindac 7.3
12-hydroperoxyeicosatetraenoic acid 7.2
2-methylpiperazine 7.2
Xamoterol 7.0
Genipin 7.0
Nitroglycerin 6.8
cAMP 6.8
CPT 6.7
Phosphoserine 6.7
BNP 6.7
Repaglinide 6.6
CPT 6.6
Tirofiban 6.6
nitric oxide 6.5
Naringenin 6.5
1,3-benzodioxole 6.5
Naringenin 6.4
Milrinone 6.4
BayK8644 6.4
NPR 6.4
dichloroacetonitrile 6.3
DCL 6.3
Forskolin 6.3
Isoliquiritigenin 6.3
6-aminonicotinamide 6.2
2-imidazolidinone 6.2
LTD 6.2
Osthole 6.2
Nobiletin 6.1
4-AP 6.1
Glu-Glu 6.1
Barbiturate 6.1
nonyl 6.0
Cinnamic acid 6.0
APT 6.0
Cytochalasin D 6.0
GC-1 5.9
Magnolol 5.9
Tempol 5.9
Sarcosine 5.8
Relaxant 5.8
Chelerythrine 5.8
Chelerythrine 5.8
BBM 5.7
Naringin 5.7
Methacholine 5.7
AET 5.7
1H-indazole 5.7
PHT 5.7
Cinnamaldehyde 5.6
phosphoserine 5.6
Protoporphyrin IX 5.6
MPT 5.6
more...