EC:2.7.11.12 - FACTA Search

Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: EC:2.7.11.12 (PKG)
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Human Gene/Protein
CGKII	13.6
PRKG1B	13.6
SGK494	13.6
PKG	13.6
GKAP42	12.9
TRIM39R	12.6
SLC8A1 protein	12.6
CT42	12.6
PKG1	12.4
G-substrate	12.4
IRAG	12.3
G-septin	12.2
cGKI	12.2
eukaryotic translation initiation factor 4E nuclear import factor 1	12.0
cGMP-stimulated phosphodiesterase 2	12.0
poliovirus receptor-related 3	12.0
CRIK	11.8
Regulator of G-protein signaling 18	11.6
synaptonemal complex protein 2	11.6
M-RIP	11.3
serine/threonine kinase 38	11.3
PLEKHA2	11.3
mitogen-activated protein kinase kinase kinase kinase 3	11.3
PRKG1	11.2
PDED	11.0
Rap1GAP2	11.0
SNAP1	11.0
myosin phosphatase regulatory subunit	10.8
PIG-F	10.8
PLEKHB1	10.8
SPHKAP	10.8
phosphodiesterase 9A	10.8
RAP2C	10.8
vasodilator-stimulated phosphoprotein	10.8
PARD6G	10.6
SLC8A2	10.6
ENOPH1	10.6
PNPLA7	10.6
cGKII	10.6
phosphodiesterase 5A	10.5

Disease
Multiple carboxylase deficiency	10.8
CNC2	10.6
FHM2	8.8
Spring viremia of carp	7.9
PDE	7.8
Waterhouse-Friderichsen syndrome	7.6
Renal interstitial fibrosis	7.5
ischemic ulcer	7.3
AD8	7.3
hypertensive cardiomyopathy	7.1
MBS	6.7
NAME	6.6
Diabetes and Pregnancy	6.3
CHH	6.2
LTD	6.2
achromatopsia	6.2
learning disorder	6.0
PAPA	6.0
Diaz	5.9
Vidal	5.9
delayed speech	5.8
MLC	5.7
erectile dysfunction	5.5
AGS	5.5
SMC	5.5
memory disorder	5.4
RGS	5.4
Vascular lesions	5.4
anxiety state	5.2
LIN	5.2
coccidiosis	5.2
anal fissure	5.1
uterine leiomyosarcoma	5.0
hearing disorder	5.0
Renal fibrosis	5.0
Bardet-Biedl syndrome	4.9
platelet disorder	4.9
Hypertrophic	4.8
CSE	4.8
Pulmonary arterial hypertension	4.8

Symptom
Lower urinary tract symptoms	6.1
Noise-induced hearing loss	6.0
rundown	4.7
clumsiness	4.5
Anoxia	4.5
orofacial pain	3.7
acute pain	3.3
bradykinesia	2.4
angina	1.8
cerebellar ataxia	1.8
memory loss	1.8
spasm	1.8
hypercapnia	1.7
hemiplegia	1.7
dystonia	1.6
myoclonus	1.6
functional recovery	1.5
collapse	1.4
cachexia	1.2
hepatomegaly	1.1
hypotonia	1.1
pain	1.0
arthralgia	0.8
diarrhea	0.8
nausea and vomiting	0.4
splenomegaly	0.4
constipation	0.3
anorexia	-0.1
respiratory distress	-0.6
cough	-0.9
starvation	-1.0
overweight	-1.1
analgesia	-1.2
vomiting	-1.3
seizures	-1.7
fatigue	-2.0
anesthesia	-2.1

Enzyme
PKG	13.6
guanylate cyclase	9.4
AMPK	8.3
protein kinase	8.3
cGMP phosphodiesterase	7.8
PDE	7.6
myosin light chain kinase	7.4
phosphodiesterase	7.3
protein phosphatase 2A	7.2
NOS	7.1
CaMKII	6.9
NO synthase	6.8
CPT	6.7
sulfiredoxin	6.7
phosphorylase kinase	6.6
CPT	6.6
protein kinase C	6.3
type 1 protein phosphatase	6.3
CPT	6.2
phosphoribulokinase	6.2
PI-PLC	6.1
rhodopsin kinase	6.0
AMP-activated kinase	5.8
guanase	5.8
sphingomyelin synthase	5.7
3-mercaptopyruvate sulfurtransferase	5.7
PRPP synthetase	5.7
PHT	5.7
PDK1	5.7
CPL	5.6
ADPase	5.5
GRK5	5.5
GRK2	5.5
calcineurin	5.4
dimethylarginine dimethylaminohydrolase	5.4
MPP	5.3
6-phosphofructo-2-kinase	5.3
propionyl-CoA carboxylase	5.2
ADP-ribosyltransferase	5.2
mu-calpain	5.2

Compound
D-NONOate	13.6
8-Bromoinosine	13.6
8-Br-cGMP	11.6
DT3	11.1
1-methylpiperidine	10.6
ethanimidamide	10.3
cGMP	9.9
Isopropylamine	9.8
p-Synephrine	9.7
4-methoxybenzenesulfonamide	9.5
C6H12O5	9.4
Sildenafil	8.7
1-methyl-1,2,3,6-tetrahydropyridine	8.7
DEA	8.7
DEA	8.7
DETA	8.6
DEA	8.6
Fostriecin	8.4
Malvidin	8.2
GMP	8.0
Ginsenoside Re	7.9
Cyclic ADP-ribose	7.7
Synephrine	7.5
Cinnamyl alcohol	7.5
GF 109203X	7.5
ITG	7.4
IAA-94	7.3
Sulindac	7.3
12-hydroperoxyeicosatetraenoic acid	7.2
2-methylpiperazine	7.2
Xamoterol	7.0
Genipin	7.0
Nitroglycerin	6.8
cAMP	6.8
CPT	6.7
Phosphoserine	6.7
BNP	6.7
Repaglinide	6.6
CPT	6.6
Tirofiban	6.6