Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:2.7.11.12 (PKG)
 2,515 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
PKG 2515
cAMP-dependent protein kinase 302
PKA 298
guanylate cyclase 289
phosphodiesterase 231
nitric oxide synthase 221
Mol 215
Sep 179
ATP 173
soluble guanylyl cyclase 171
guanylyl cyclase 164
PKC 161
calmodulin 110
vasodilator-stimulated phosphoprotein 89
atrial natriuretic peptide 80
MAPK 78
threonine 72
phosphatase 70
ATPase 65
natriuretic peptide 63
more...
Disease
NAME 100
hypertension 79
cancer 77
heart failure 63
ischemia 63
tumor 60
PDE 45
depression 44
diabetes 37
malaria 33
atherosclerosis 31
pertussis 27
erectile dysfunction 25
pulmonary hypertension 24
Alzheimer's disease 24
obesity 22
stroke 21
SDS 20
colon cancer 16
neuroblastoma 16
more...
Symptom
pain 40
diarrhea 8
collapse 6
angina 6
functional recovery 3
acute pain 3
seizures 2
anesthesia 2
dystonia 2
hypercapnia 2
spasm 2
cough 1
overweight 1
nausea and vomiting 1
Lower urinary tract symptoms 1
hypotonia 1
clumsiness 1
orofacial pain 1
hepatomegaly 1
rundown 1
more...
Drug
Cardiovasc 25
Nitric Oxide 19
nitroglycerin 18
caffeine 17
Forskolin 16
Sodium nitroprusside 15
ROS 15
Angiotensin II 11
lysine 11
MAP 9
Monit 8
GEO 4
Heme 4
Viagra 4
Asn 4
NADH 4
CIA 4
Methylene blue 4
IFN-gamma 4
Nephron 4
more...
Enzyme
PKG 2515
protein kinase 2085
guanylate cyclase 453
AMPK 319
protein kinase C 310
phosphodiesterase 231
mitogen-activated protein kinase 181
NO synthase 143
NOS 77
ATPase 65
ERK 60
calcineurin 59
PDE 58
CaMKII 39
myosin light chain kinase 36
phospholipase C 35
thrombin 34
protein phosphatase 2A 34
MEK 32
adenylate cyclase 30
more...
Compound
cGMP 1590
nitric oxide 715
cAMP 502
calcium 454
sodium 242
Dec 189
GMP 181
ATP 173
arginine 167
8-Br-cGMP 158
serine 127
threonine 103
oxygen 94
phosphate 77
potassium 75
DNA 71
AMP 64
glucose 57
tyrosine 54
alanine 54
more...