Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:2.7.11.11 (AMPK)
12,425 document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
AMPK 6226
cAMP-dependent protein kinase 6110
ATP 1352
insulin 1284
mTOR 1266
Mol 1171
AMP 736
Sep 726
AMP-activated protein kinase 537
calmodulin 506
PI3K 413
adenylate cyclase 410
AKT 408
LKB1 387
PKA 374
phosphodiesterase 346
PGC 332
MAPK 327
PKG 319
phosphatase 316
adiponectin 312
LC3 298
SIRT1 291
threonine 273
p53 271
ROS 259
adenylyl cyclase 248
AICAR 237
TNF 237
ERK 232
p38 226
caspase-3 220
ACC 216
ULK1 206
ATPase 202
endoplasmic reticulum 199
p62 199
PKC 188
phosphoprotein 186
ERK1 180
JNK 178
protein phosphatase 177
glucagon 174
histone 171
protein kinase inhibitor 169
Bcl-2 167
leptin 166
GLUT4 165
IL-6 163
polypeptide 160
acetyl-CoA carboxylase 156
ADP 154
GTP 153
cytokine 153
Beclin-1 150
PKI 148
peroxisome proliferator-activated receptor 142
PPAR 135
Nrf2 135
SDS 130
CREB 129
phosphorylating 125
tyrosine kinase 116
IRS-1 111
phospholamban 108
casein 106
p21 106
tumor necrosis factor 104
lipopolysaccharide 103
CPT 103
ubiquitin 103
collagen 103
eNOS 101
calcineurin 100
Adiponectin 100
Dictyostelium 100
alkaline phosphatase 99
superoxide dismutase 96
FAS 95
phosphorylase kinase 95
more...
Disease
cancer 1250
tumor 787
obesity 659
diabetes 646
type 2 diabetes 387
fatty liver 206
breast cancer 202
hepatocellular carcinoma 184
tumor growth 178
hyperglycemia 176
ischemia 162
Alzheimer's disease 151
tumorigenesis 141
SDS 130
metabolic syndrome 123
atherosclerosis 116
hypertension 102
cholera 101
heart failure 100
depression 99
FAS 97
prostate cancer 91
lung cancer 90
cardiovascular disease 87
pertussis 84
tumor progression 81
colorectal cancer 79
carcinoma 77
hyperlipidemia 76
lymphoma 72
glucose intolerance 71
carcinogenesis 71
dyslipidemia 70
MCF 68
Parkinson's disease 68
stroke 68
leukemia 66
myocardial ischemia 65
GSH 64
myocardial infarction 63
adenocarcinoma 62
neuroblastoma 62
glioma 59
alcoholic fatty liver 59
melanoma 55
ATM 54
cold 54
colon cancer 49
pancreatic cancer 46
non-small cell lung cancer 44
glioblastoma 43
tuberous sclerosis 43
diabetic nephropathy 41
cerebral ischemia 40
liver disease 39
NAME 38
sepsis 38
sepsis 38
osteosarcoma 38
hypoglycemia 36
cystic fibrosis 36
liver cancer 36
ovarian cancer 35
gastric cancer 34
PDE 33
cognitive impairment 33
pheochromocytoma 32
cardiomyopathy 32
metabolic disorder 32
liver fibrosis 31
hyperinsulinemia 31
HIV 30
acute myeloid leukemia 30
squamous cell carcinoma 29
liver cancer 29
mole 28
mole 28
diabetic cardiomyopathy 28
Blocking 28
renal cell carcinoma 27
more...
Symptom
starvation 184
pain 47
fatigue 31
collapse 27
functional recovery 21
exhaustion 20
overweight 20
cachexia 14
diarrhea 13
seizures 13
weakness 11
anesthesia 10
hunger 10
memory loss 8
hypothermia 7
respiratory distress 6
thinning 5
ataxia 5
rundown 5
anorexia 5
hypercapnia 4
analgesia 4
hepatomegaly 4
stigma 4
hyperoxia 4
tremor 4
low back pain 3
bradykinesia 2
Anoxia 2
chills 2
angina 2
acute pain 2
Neuropathic pain 2
insomnia 2
cough 2
menopausal symptoms 2
back pain 2
pallor 2
Cushingoid 1
vomiting 1
syncope 1
stomach cramps 1
myalgia 1
Catch 1
muscle rigidity 1
twitching 1
spasticity 1
shoulder pain 1
bitter taste 1
nausea 1
constipation 1
ophthalmoplegia 1
acidity 1
HSA 1
cyanosis 1
hemoptysis 1
incoordination 1
dyspnea 1
POA 1
Cushingoid 1
Scratch 1
skin damage 1
headache 1
abdominal pain 1
neurological disability 1
Spots 1
Ill 1
Drug
ROS 259
Forskolin 114
lysine 78
Asn 42
NADH 38
MAP 37
Glucagon 35
caffeine 33
Parkin 29
Parkin 29
Gel 28
Cardiovasc 28
PTH 25
Ethanol 21
Monit 21
CaCl2 17
CaCl2 17
CaCl2 17
IL-2 16
Dermatol 13
Ginseng 13
RFP 13
Rolipram 12
DNase I 12
Retinoic acid 11
Liraglutide 11
K-252a 11
Fructose 11
Nephron 11
IFN-gamma 11
ascorbate 11
CSF 10
Rosiglitazone 10
Histamine 9
vitamin E 9
L-tyrosine 8
citric acid 8
Cilostazol 8
CAM 7
Sodium nitroprusside 7
Leaf 7
BH4 7
Itraconazole 7
EE2 7
ALA 7
Sorafenib 7
3-Methyladenine 7
G418 6
Arsenic trioxide 6
Angiotensin II 6
Iloprost 6
Emodin 5
Glycyrrhiza 5
Nitric Oxide 5
Emodin 5
Alanine 5
-deoxyadenosine 5
ICI 5
NH3 5
Trifluoperazine 5
TAK 5
Ara-A 5
EPA 5
Simvastatin 5
Adriamycin 4
Acadesine 4
Salicylate 4
Kenyan 4
GEO 4
Indomethacin 4
Adenosine Monophosphate 4
Glycerol 4
Methylene blue 4
Docetaxel 4
Taxol 4
Ezetimibe 4
Troglitazone 4
Portal 4
Orlistat 4
nitroglycerin 4
more...
Enzyme
AMPK 12425
protein kinase 6885
AMP-activated protein kinase 6254
AMPK 6226
protein kinase C 884
mitogen-activated protein kinase 817
adenylate cyclase 434
calcineurin 358
ERK 353
phosphodiesterase 348
PKG 319
CaMKII 244
ATPase 212
acetyl-CoA carboxylase 162
focal adhesion kinase 158
caspase-3 153
superoxide dismutase 152
CPT 135
phosphorylase 122
phosphorylase kinase 112
trypsin 111
CPT 103
CPT 103
MEK 101
alkaline phosphatase 99
phospholipase C 98
myosin light chain kinase 91
luciferase 89
proteasome 88
catalase 86
PARP 86
alanine aminotransferase 82
GSK 81
polo-like kinase 1 80
PDE 78
complex I 76
hormone-sensitive lipase 75
aspartate aminotransferase 74
tyrosine hydroxylase 74
phosphatidylinositol 3-kinase 71
phosphoenolpyruvate carboxykinase 69
lactate dehydrogenase 55
glutathione S-transferase 55
lipase 54
guanylate cyclase 52
NO synthase 49
citrate synthase 49
thrombin 49
protein phosphatase 2A 49
TOR 48
pyruvate kinase 48
PDK1 46
phosphofructokinase 43
phosphoenolpyruvate carboxykinase 38
phosphoenolpyruvate carboxykinase 38
NADPH oxidase 37
NADPH oxidase 37
AST 37
glutathione peroxidase 33
lipoprotein lipase 31
AMP-activated kinase 31
peroxidase 30
IKK 30
ATP synthase 30
chymotrypsin 29
creatine kinase 29
caspase-1 29
NOS 29
cdc2 26
6-phosphofructo-2-kinase 26
trehalase 25
glucose-6-phosphatase 25
NQO1 25
phosphoinositide 3-kinase 25
STK11 24
chloramphenicol acetyltransferase 24
urokinase-type plasminogen activator 23
pyruvate dehydrogenase 23
caspase-9 23
hexokinase 23
more...
Compound
cAMP 3049
glucose 1607
ATP 1352
calcium 1310
Dec 850
AMP 839
DNA 655
oxygen 654
phosphate 622
serine 593
threonine 518
sodium 428
cGMP 384
alanine 292
Metformin 284
Metformin 284
arginine 282
tyrosine 278
AICAR 252
AICAR 239
TNF 237
acetate 234
water 232
sulfate 206
Clin 200
adenylate 190
nitric oxide 177
DEAE 166
ADP 163
Insulin 157
leucine 155
GTP 155
ADP 154
ADP 154
lysine 151
SDS 141
Mg2+ 138
hydrogen 127
glutamate 124
salt 116
Forskolin 114
Gly 110
ethanol 109
methionine 108
NAD 106
potassium 105
CPT 103
CPT 103
cysteine 96
glycerol 91
Phe 89
Asp 88
NH2 85
NAD 85
MDA 82
galactose 82
nitrogen 80
Cardiol 79
ACTH 79
MTT 77
Resveratrol 75
urea 71
palmitic acid 70
CoA 67
His 66
GSH 65
Ile 65
GSH 65
MEK 64
phosphoserine 63
bromide 59
glutamine 59
prostaglandin E1 55
manganese 53
proline 51
Isoproterenol 50
Triton X-100 50
palmitic acid 48
retinoic acid 42
N-acetylcysteine 42
more...