Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:2.7.11.11 (AMPK)
12,425 document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
AMPK 6226
cAMP-dependent protein kinase 6110
ATP 1352
insulin 1284
mTOR 1266
Mol 1171
AMP 736
Sep 726
AMP-activated protein kinase 537
calmodulin 506
PI3K 413
adenylate cyclase 410
AKT 408
LKB1 387
PKA 374
phosphodiesterase 346
PGC 332
MAPK 327
PKG 319
phosphatase 316
adiponectin 312
LC3 298
SIRT1 291
threonine 273
p53 271
ROS 259
adenylyl cyclase 248
AICAR 237
TNF 237
ERK 232
p38 226
caspase-3 220
ACC 216
ULK1 206
ATPase 202
p62 199
endoplasmic reticulum 199
PKC 188
phosphoprotein 186
ERK1 180
more...
Disease
cancer 1250
tumor 787
obesity 659
diabetes 646
type 2 diabetes 387
fatty liver 206
breast cancer 202
hepatocellular carcinoma 184
tumor growth 178
hyperglycemia 176
ischemia 162
Alzheimer's disease 151
tumorigenesis 141
SDS 130
metabolic syndrome 123
atherosclerosis 116
hypertension 102
cholera 101
heart failure 100
depression 99
FAS 97
prostate cancer 91
lung cancer 90
cardiovascular disease 87
pertussis 84
tumor progression 81
colorectal cancer 79
carcinoma 77
hyperlipidemia 76
lymphoma 72
carcinogenesis 71
glucose intolerance 71
dyslipidemia 70
stroke 68
Parkinson's disease 68
MCF 68
leukemia 66
myocardial ischemia 65
GSH 64
myocardial infarction 63
more...
Symptom
starvation 184
pain 47
fatigue 31
collapse 27
functional recovery 21
exhaustion 20
overweight 20
cachexia 14
diarrhea 13
seizures 13
weakness 11
hunger 10
anesthesia 10
memory loss 8
hypothermia 7
respiratory distress 6
thinning 5
rundown 5
ataxia 5
anorexia 5
hypercapnia 4
analgesia 4
stigma 4
hyperoxia 4
tremor 4
hepatomegaly 4
low back pain 3
bradykinesia 2
Anoxia 2
chills 2
angina 2
Neuropathic pain 2
pallor 2
menopausal symptoms 2
back pain 2
insomnia 2
cough 2
acute pain 2
Cushingoid 1
vomiting 1
more...
Drug
ROS 259
Forskolin 114
lysine 78
Asn 42
NADH 38
MAP 37
Glucagon 35
caffeine 33
Parkin 29
Parkin 29
Cardiovasc 28
Gel 28
PTH 25
Ethanol 21
Monit 21
CaCl2 17
CaCl2 17
CaCl2 17
IL-2 16
Ginseng 13
RFP 13
Dermatol 13
DNase I 12
Rolipram 12
ascorbate 11
K-252a 11
IFN-gamma 11
Retinoic acid 11
Fructose 11
Liraglutide 11
Nephron 11
CSF 10
Rosiglitazone 10
Histamine 9
vitamin E 9
Cilostazol 8
L-tyrosine 8
citric acid 8
BH4 7
3-Methyladenine 7
more...
Enzyme
AMPK 12425
protein kinase 6885
AMP-activated protein kinase 6254
AMPK 6226
protein kinase C 884
mitogen-activated protein kinase 817
adenylate cyclase 434
calcineurin 358
ERK 353
phosphodiesterase 348
PKG 319
CaMKII 244
ATPase 212
acetyl-CoA carboxylase 162
focal adhesion kinase 158
caspase-3 153
superoxide dismutase 152
CPT 135
phosphorylase 122
phosphorylase kinase 112
trypsin 111
CPT 103
CPT 103
MEK 101
alkaline phosphatase 99
phospholipase C 98
myosin light chain kinase 91
luciferase 89
proteasome 88
catalase 86
PARP 86
alanine aminotransferase 82
GSK 81
polo-like kinase 1 80
PDE 78
complex I 76
hormone-sensitive lipase 75
tyrosine hydroxylase 74
aspartate aminotransferase 74
phosphatidylinositol 3-kinase 71
more...
Compound
cAMP 3049
glucose 1607
ATP 1352
calcium 1310
Dec 850
AMP 839
DNA 655
oxygen 654
phosphate 622
serine 593
threonine 518
sodium 428
cGMP 384
alanine 292
Metformin 284
Metformin 284
arginine 282
tyrosine 278
AICAR 252
AICAR 239
TNF 237
acetate 234
water 232
sulfate 206
Clin 200
adenylate 190
nitric oxide 177
DEAE 166
ADP 163
Insulin 157
GTP 155
leucine 155
ADP 154
ADP 154
lysine 151
SDS 141
Mg2+ 138
hydrogen 127
glutamate 124
salt 116
more...