Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: EC:2.7.11.11 (
AMPK
)
12,425
document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
AMPK
6226
cAMP-dependent protein kinase
6110
ATP
1352
insulin
1284
mTOR
1266
Mol
1171
AMP
736
Sep
726
AMP-activated protein kinase
537
calmodulin
506
PI3K
413
adenylate cyclase
410
AKT
408
LKB1
387
PKA
374
phosphodiesterase
346
PGC
332
MAPK
327
PKG
319
phosphatase
316
adiponectin
312
LC3
298
SIRT1
291
threonine
273
p53
271
ROS
259
adenylyl cyclase
248
AICAR
237
TNF
237
ERK
232
p38
226
caspase-3
220
ACC
216
ULK1
206
ATPase
202
p62
199
endoplasmic reticulum
199
PKC
188
phosphoprotein
186
ERK1
180
more...
Disease
cancer
1250
tumor
787
obesity
659
diabetes
646
type 2 diabetes
387
fatty liver
206
breast cancer
202
hepatocellular carcinoma
184
tumor growth
178
hyperglycemia
176
ischemia
162
Alzheimer's disease
151
tumorigenesis
141
SDS
130
metabolic syndrome
123
atherosclerosis
116
hypertension
102
cholera
101
heart failure
100
depression
99
FAS
97
prostate cancer
91
lung cancer
90
cardiovascular disease
87
pertussis
84
tumor progression
81
colorectal cancer
79
carcinoma
77
hyperlipidemia
76
lymphoma
72
carcinogenesis
71
glucose intolerance
71
dyslipidemia
70
stroke
68
Parkinson's disease
68
MCF
68
leukemia
66
myocardial ischemia
65
GSH
64
myocardial infarction
63
more...
Symptom
starvation
184
pain
47
fatigue
31
collapse
27
functional recovery
21
exhaustion
20
overweight
20
cachexia
14
diarrhea
13
seizures
13
weakness
11
hunger
10
anesthesia
10
memory loss
8
hypothermia
7
respiratory distress
6
thinning
5
rundown
5
ataxia
5
anorexia
5
hypercapnia
4
analgesia
4
stigma
4
hyperoxia
4
tremor
4
hepatomegaly
4
low back pain
3
bradykinesia
2
Anoxia
2
chills
2
angina
2
Neuropathic pain
2
pallor
2
menopausal symptoms
2
back pain
2
insomnia
2
cough
2
acute pain
2
Cushingoid
1
vomiting
1
more...
Drug
ROS
259
Forskolin
114
lysine
78
Asn
42
NADH
38
MAP
37
Glucagon
35
caffeine
33
Parkin
29
Parkin
29
Cardiovasc
28
Gel
28
PTH
25
Ethanol
21
Monit
21
CaCl2
17
CaCl2
17
CaCl2
17
IL-2
16
Ginseng
13
RFP
13
Dermatol
13
DNase I
12
Rolipram
12
ascorbate
11
K-252a
11
IFN-gamma
11
Retinoic acid
11
Fructose
11
Liraglutide
11
Nephron
11
CSF
10
Rosiglitazone
10
Histamine
9
vitamin E
9
Cilostazol
8
L-tyrosine
8
citric acid
8
BH4
7
3-Methyladenine
7
more...
Enzyme
AMPK
12425
protein kinase
6885
AMP-activated protein kinase
6254
AMPK
6226
protein kinase C
884
mitogen-activated protein kinase
817
adenylate cyclase
434
calcineurin
358
ERK
353
phosphodiesterase
348
PKG
319
CaMKII
244
ATPase
212
acetyl-CoA carboxylase
162
focal adhesion kinase
158
caspase-3
153
superoxide dismutase
152
CPT
135
phosphorylase
122
phosphorylase kinase
112
trypsin
111
CPT
103
CPT
103
MEK
101
alkaline phosphatase
99
phospholipase C
98
myosin light chain kinase
91
luciferase
89
proteasome
88
catalase
86
PARP
86
alanine aminotransferase
82
GSK
81
polo-like kinase 1
80
PDE
78
complex I
76
hormone-sensitive lipase
75
tyrosine hydroxylase
74
aspartate aminotransferase
74
phosphatidylinositol 3-kinase
71
more...
Compound
cAMP
3049
glucose
1607
ATP
1352
calcium
1310
Dec
850
AMP
839
DNA
655
oxygen
654
phosphate
622
serine
593
threonine
518
sodium
428
cGMP
384
alanine
292
Metformin
284
Metformin
284
arginine
282
tyrosine
278
AICAR
252
AICAR
239
TNF
237
acetate
234
water
232
sulfate
206
Clin
200
adenylate
190
nitric oxide
177
DEAE
166
ADP
163
Insulin
157
GTP
155
leucine
155
ADP
154
ADP
154
lysine
151
SDS
141
Mg2+
138
hydrogen
127
glutamate
124
salt
116
more...