Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:2.7.11.10 (IKK)
 4,900 document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
IKBKB protein 12.7
Parkinson disease (autosomal recessive, juvenile) 2, parkin 12.7
TMEM203 12.7
IKBKA 12.7
IFITM2 protein 12.7
G patch domain-containing protein 3 12.7
TBK1 12.7
RAS-like GTPase 12.7
IKBKB 12.7
ZSWIM4 12.7
CHUK 12.7
TANK-binding kinase 1 12.7
transporter for antigen processing 1 12.7
peroxisomal biogenesis factor 3 12.7
FBXO18 12.7
IKK 12.7
IkappaB kinase 12.6
IKK epsilon 12.1
SIKE 12.0
conserved helix-loop-helix ubiquitous kinase 11.9
AZI2 11.9
SINTBAD 11.9
ADCK2 11.7
LMTK2 protein 11.7
TRAF family member-associated NF-kappa-B activator 11.7
ASB8 11.7
TBC1 domain family member 9 11.7
ubiquitin specific peptidase 10 11.7
TANK protein 11.7
ZDHHC11 11.7
zinc finger protein 268 11.7
ankyrin repeat and SOCS box-containing 8 11.7
coilin-interacting nuclear ATPase protein 11.7
TBC1 domain family member 15 11.7
G1/S-specific cyclin E2 11.7
NAK-associated protein 1 11.7
EID-2-like inhibitor of differentiation-3 11.7
IKK1 11.7
IKK2 11.4
IKK-interacting protein 11.3
TANK 11.3
MITA 11.1
OTUD2 11.1
wingless-type MMTV integration site family, member 1 11.1
Erbb2 interacting protein 11.1
TBC1D17 11.1
LIPJ 11.1
ZNF268 protein 11.1
AP2 associated kinase 1 11.1
SPTY2D1 11.1
TXBP151 11.1
LPAL2 11.1
RAB2A, member RAS oncogene family 11.1
TRAF3 interacting protein 2 11.1
serine/threonine kinase 24 11.1
IKBKE 11.0
IkappaBepsilon 11.0
NFkappaB essential modulator 10.9
Deltex4 10.9
NLRP4 10.7
NEMO 10.7
TNF receptor-associated factor 5 10.7
OSBPL8 10.7
ZF7 10.7
ZNF395 10.7
transportin 2 10.7
CCL27 protein 10.7
Interleukin-1 receptor associated kinase-4 10.7
ATP-dependent RNA helicase DDX3X 10.7
TXBP181 10.7
PLA1A 10.7
SID1 transmembrane family member 2 10.7
TMEM24 10.7
IRF3 10.6
IkappaBbeta 10.6
LMBR1 10.5
NIK 10.5
ERLIN1 10.5
XPOT 10.5
TRIM56 10.5
more...
Disease
chronic tracheitis 9.2
CYLD 9.2
EDA-ID 9.1
Sendai virus infection 8.9
NEK1 8.8
VISA 8.5
Spring viremia of carp 7.9
ABC-DLBCL 7.9
Aortic calcification 7.9
incontinentia pigmenti 7.8
MODY4 7.7
Escherichia coli pneumonia 7.5
Hypertensive retinopathy 7.4
Hypertensive retinopathy 7.4
EBSS 7.1
viral keratitis 7.1
SPG11 6.9
FTD-ALS 6.8
Gram-positive bacterial infection 6.8
Cytokine storm 6.8
Epithelioma 6.6
viral arthritis 6.6
Papillary renal cell carcinoma 6.5
Other variants 6.3
AA1 6.2
Lumbar disc herniation 6.2
Cutaneous lupus erythematosus 6.1
low tension glaucoma 6.1
ectodermal dysplasia 6.1
Primary effusion lymphoma 6.1
Splenic marginal zone lymphoma 6.0
FUS 5.9
Herpes simplex encephalitis 5.9
Advanced cancer 5.9
Meconium aspiration syndrome 5.9
herpangina 5.9
Frontotemporal dementia 5.8
Oral infection 5.7
ALS2 5.7
PLAT 5.7
acute gastritis 5.6
FTLD 5.6
Chronic gastritis 5.6
early disease onset 5.5
Vesicular stomatitis 5.5
ocular herpes 5.5
familial dysautonomia 5.5
adult T-cell leukemia/lymphoma 5.4
Cancer cachexia 5.4
Psoriasis vulgaris 5.4
salivary gland cancer 5.4
lymphoblastoma 5.4
ISD 5.3
osteopoikilosis 5.3
sandfly fever 5.2
Primary open-angle glaucoma 5.1
FANCI 5.1
XFS 5.1
molluscum contagiosum 5.1
Primary immunodeficiency 5.0
US1 5.0
DRM 5.0
Lequesne 5.0
X-linked lymphoproliferative syndrome 5.0
Middle cerebral artery occlusion 5.0
primary lateral sclerosis 5.0
HOPS 4.9
Borna disease 4.9
virus infection 4.8
liver infection 4.8
B-cell neoplasm 4.8
HNSCC 4.8
CCL 4.7
Autosomal recessive polycystic kidney disease 4.7
multicentric Castleman's disease 4.6
inflammatory joint disease 4.6
skin tumor 4.6
overnutrition 4.6
stomatitis 4.6
Mixed infection 4.5
more...
Symptom
impaired motor coordination 5.1
bradypnea 5.0
Scratch 4.0
Decreased activity 3.6
swollen joints 3.6
cachexia 2.8
productive cough 2.5
Neuropathic pain 2.2
menopausal symptoms 2.0
starvation 2.0
memory loss 1.8
acute stress 1.5
dysuria 1.4
hyperoxia 1.3
hypothermia 1.2
polyuria 1.1
cancer pain 1.1
bone pain 1.1
cerebellar ataxia 0.8
diarrhea 0.8
apathy 0.7
erythema 0.6
splenomegaly 0.4
paresthesia 0.4
ataxia 0.3
insomnia 0.3
hepatomegaly 0.2
paresis 0.2
hypotonia 0.1
functional recovery -0.0
exhaustion -0.1
arthralgia -0.1
hypercapnia -0.3
collapse -0.6
dizziness -0.6
vomiting -0.7
nausea -0.9
fatigue -1.0
pain -1.0
overweight -1.0
anorexia -1.1
analgesia -1.1
weakness -1.5
angina -1.7
cough -1.9
seizures -3.6
anesthesia -4.1
Drug
Pelubiprofen 11.1
Amlexanox 10.4
Ertiprotafib 10.3
E5564 7.5
Myotrophin 7.2
IFN-beta 6.8
Radicicol 6.6
Auranofin 6.6
TAK 6.4
Vesnarinone 6.4
Ciglitazone 6.4
RAL 6.3
Glybenclamide 6.0
Compound 16 6.0
Fluticasone propionate 5.8
Red ginseng 5.8
NAH 5.7
Febuxostat 5.5
Vinpocetine 5.5
Darunavir 5.4
Rebamipide 5.4
Rasagiline 5.4
Nitazoxanide 5.4
Ginger 5.4
3-Methyladenine 5.3
Artesunate 5.2
Salicylate 5.1
Dasatinib 5.0
BLyS 5.0
Parkin 5.0
Parkin 5.0
Bortezomib 4.7
Arsenic trioxide 4.7
CCL 4.7
ID2 4.5
Myricetin 4.4
K-252a 4.2
uPA 4.2
Fulvestrant 4.2
Glycyrrhiza 4.2
IL-11 4.1
Retinoic acid 4.1
CIA 4.0
ROS 4.0
Rosiglitazone 4.0
Epigallocatechin 3.9
Moxifloxacin 3.8
Emodin 3.8
Dihydro 3.6
Taxol 3.6
Troglitazone 3.6
Simvastatin 3.6
p75 3.5
Papain 3.5
MAP 3.5
GHRP 3.5
Emodin 3.5
CPM 3.5
Gefitinib 3.4
Imatinib 3.4
Taxotere 3.4
Budesonide 3.4
R1881 3.4
Kainic acid 3.3
IL-2 3.2
Heme 3.1
TEL 3.1
TAT 3.0
Ginseng 3.0
lysine 2.9
Gelatin 2.9
Docetaxel 2.9
APD 2.8
DEX 2.8
Alanine 2.8
Fructose 2.8
IFN-gamma 2.7
Acyclovir 2.6
CTC 2.6
Doxycycline 2.6
more...
Enzyme
IKK 12.7
phosphatidylinositol 3-phosphate 5-kinase 8.7
p100 8.6
MEKK1 8.1
HK3 7.9
STK4 7.2
GK2 7.2
aggrecanase-1 6.7
MHCK 6.6
diaminopimelate decarboxylase 6.5
octopine dehydrogenase 6.4
choline dehydrogenase 6.4
caspase-11 6.2
caspase-11 6.2
methylcrotonyl-CoA carboxylase 6.2
caspase-10 6.1
MEK 5.7
ECH 5.6
mitogen-activated protein kinase 5.6
GalT 5.5
7-dehydrocholesterol reductase 5.5
macrophage elastase 5.5
calpain 3 5.4
glycine N-methyltransferase 5.4
ubiquitin-protein ligase 5.3
caspase-8 5.3
proteasome 5.3
type 1 protein phosphatase 5.3
disulfide reductase 5.3
phosphoinositide 3-kinase 5.2
phosphatidylinositol 3-kinase 5.2
caspase-10 5.2
PDK1 5.1
GD3 synthase 5.1
AMPK 5.0
polo-like kinase 1 4.9
neutral sphingomyelinase 4.9
mu-calpain 4.8
protein phosphatase 2A 4.8
STK11 4.8
luciferase 4.7
3C protease 4.7
NO synthase 4.7
lysyl hydroxylase 4.7
sphingosine kinase 4.7
caspase-1 4.7
MAP 4.7
GSK 4.6
AMP-activated protein kinase 4.6
HK2 4.5
meprin 4.5
GRK2 4.5
protein kinase 4.4
dimethylarginine dimethylaminohydrolase 4.4
PARP 4.3
ceramidase 4.3
MIP 4.2
NADPH oxidase 4.2
NADPH oxidase 4.2
guanylate kinase 4.2
TOR 4.1
protein kinase C 4.1
caspase-2 4.1
ERK 4.1
TACE 4.0
caspase-2 4.0
calcineurin 4.0
AMPK 4.0
focal adhesion kinase 3.9
calpain 3 3.9
Protein 2 3.9
caspase-3 3.9
CGT 3.9
caspase-7 3.9
myosin light chain kinase 3.9
caspase-7 3.8
caspase-9 3.8
caspase-6 3.8
gamma-glutamylcysteine synthetase 3.8
glucosylceramide synthase 3.8
more...
Compound
C13H9ClFNO2 12.7
Robinin 10.3
Robinin 10.3
Humulone 10.1
Nodakenin 10.1
Tylophorine 9.8
Ovatodiolide 9.8
Ginkgolide C 9.7
Wedelolactone 9.6
Malabaricone C 9.3
Taraxerol 9.2
Monotropein 9.2
Miltirone 9.2
Taraxerol 9.2
DuP 697 9.1
Sulfuretin 9.0
Pachymic acid 8.9
Ginkgolide C 8.8
Humulone 8.6
Prunetin 8.5
Deoxyelephantopin 8.5
Isovitexin 8.3
Sarsasapogenin 8.3
Gramine 8.1
TPCK 8.1
Magnoflorine 8.1
Psoralidin 8.0
4-Thiouridine 8.0
Ginsenoside Re 7.9
Falcarindiol 7.9
Arctiin 7.9
Parthenolide 7.8
Eupatilin 7.8
Fangchinoline 7.7
Guggulsterone 7.7
2,6-dichloropyridine 7.7
Swertiamarin 7.7
Boswellic acid 7.6
Dihydromyricetin 7.6
Parthenolide 7.6
Celastrol 7.5
Iturin A 7.4
Butein 7.3
RELA 7.2
Gambogic acid 7.2
Withaferin A 7.2
Daphnetin 7.0
Carnosic acid 7.0
Pristimerin 6.9
Pristimerin 6.9
Ginkgolide B 6.9
Pristimerin 6.9
Pristimerin 6.9
Flavone acetic acid 6.9
Alantolactone 6.9
HFr 6.8
CUE 6.8
Bergenin 6.8
Diosmetin 6.7
Digitoxin 6.7
Acacetin 6.7
Cryptoxanthin 6.6
Carnosol 6.6
celastrol 6.6
1-heptene 6.6
Benznidazole 6.6
Benznidazole 6.6
Benznidazole 6.6
3-cyanopyridine 6.6
Garcinol 6.6
pentyl acetate 6.6
thieno[2,3-b]pyridine 6.5
Glabridin 6.5
4-hydroxy-3-methoxybenzaldehyde 6.5
4-hydroxy-3-methoxybenzaldehyde 6.5
Tangeretin 6.5
PRD 6.5
Chrysin 6.4
Surfactin 6.4
Manumycin 6.4
more...