Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts: Gene/Protein Disease Symptom Drug Enzyme Compound   Target Concepts: Gene/Protein Disease Symptom Drug Enzyme Compound

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Query: EC:2.7.11.10 (IKK)
4,900 document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .

Human Gene/Protein IKK 2478 IkappaB kinase 1468 TBK1 766 p65 755 Mol 564 cytokine 554 TNF 506 IkappaBalpha 499 tumor necrosis factor 473 interferon 422 lipopolysaccharide 348 IL-6 339 IFN 334 p38 330 Sep 321 IRF3 318 TANK-binding kinase 1 314 JNK 289 NEMO 269 ubiquitin 267 LPS 257 MAPK 225 TLR4 217 inducible nitric oxide synthase 210 TNF-alpha 198 RIG-I 179 STING 179 IL-8 177 p50 174 ERK 173 proteasome 172 TAK1 152 TRAF6 151 insulin 148 IKK2 147 MyD88 146 AP-1 145 type I interferon 144 interferon regulatory factor 3 141 tumor necrosis factor alpha 136 more...

Disease cancer 726 tumor 433 virus infection 215 tumorigenesis 152 breast cancer 120 leukemia 100 obesity 96 rheumatoid arthritis 85 diabetes 78 carcinogenesis 78 hepatocellular carcinoma 69 amyotrophic lateral sclerosis 67 tumor progression 64 tumor growth 57 lymphoma 55 prostate cancer 53 arthritis 53 ischemia 53 sepsis 52 atherosclerosis 51 type 2 diabetes 51 immunodeficiency 50 melanoma 49 sepsis 49 carcinoma 48 influenza 46 lung cancer 43 herpes simplex 42 infectious diseases 41 asthma 39 colitis 39 HIV 38 multiple myeloma 38 B-cell lymphoma 37 dementia 37 MCF 36 Alzheimer's disease 33 hepatitis C 33 adenocarcinoma 33 stomatitis 32 more...

Symptom pain 20 starvation 15 diarrhea 15 cachexia 6 hypothermia 6 fatigue 4 erythema 3 collapse 3 vomiting 3 ataxia 3 weakness 2 splenomegaly 2 overweight 2 insomnia 2 functional recovery 2 nausea 2 analgesia 2 memory loss 2 acute stress 2 hyperoxia 2 exhaustion 2 anesthesia 1 cough 1 dysuria 1 Neuropathic pain 1 productive cough 1 angina 1 paresis 1 apathy 1 hypotonia 1 paresthesia 1 Scratch 1 swollen joints 1 anorexia 1 dizziness 1 hepatomegaly 1 impaired motor coordination 1 hypercapnia 1 seizures 1 Decreased activity 1 more...

Drug lysine 68 IFN-beta 52 ROS 49 IL-2 42 MAP 28 IFN-gamma 28 CSF 16 Dermatol 13 TAK 13 Retinoic acid 9 Amlexanox 9 Parkin 9 Parkin 9 p75 7 Taxol 6 uPA 6 Gel 6 Bortezomib 6 Arsenic trioxide 5 ascorbate 5 Asthma 5 Auranofin 5 CCL 5 vitamin E 4 Heme 4 Glycyrrhiza 4 Imatinib 4 Monit 3 TAT 3 Cardiovasc 3 Glutathione 3 Salicylate 3 Asn 3 Angiotensin II 3 RAL 3 Alanine 3 IL-11 3 Simvastatin 3 Dasatinib 3 Ginger 3 more...

Enzyme IKK 4900 mitogen-activated protein kinase 725 protein kinase 269 ERK 245 proteasome 175 luciferase 157 MEK 149 protein kinase C 130 focal adhesion kinase 103 caspase-3 82 MEKK1 81 NO synthase 64 phosphatidylinositol 3-kinase 62 p100 55 AMP-activated protein kinase 50 glutathione S-transferase 42 caspase-8 42 calcineurin 42 PARP 41 peroxidase 34 phosphoinositide 3-kinase 33 NADPH oxidase 32 catalase 31 AMPK 30 superoxide dismutase 30 AMPK 30 MAP 29 NADPH oxidase 29 GSK 26 caspase-1 25 phospholipase C 20 caspase-9 16 collagenase 15 urokinase-type plasminogen activator 14 MIP 14 protein phosphatase 2A 13 RNA polymerase 13 PDK1 12 thrombin 12 NQO1 11 more...

Compound DNA 717 TNF 506 Dec 308 serine 224 oxygen 207 nitric oxide 148 lysine 105 glucose 103 tyrosine 98 threonine 87 Clin 82 MEK 74 AMP 72 acetate 69 alanine 56 sodium 54 cGMP 54 calcium 52 THP 52 cysteine 51 ATP 51 THP 51 PGE 46 MDA 39 PMA 37 hydrogen 36 PMA 36 water 34 GSH 33 GSH 33 ethanol 32 Curcumin 31 N-acetylcysteine 30 MAP 28 leucine 27 arginine 27 phosphate 26 PGE2 26 cAMP 26 pyrrolidine 24 more...

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