Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts: Gene/Protein Disease Symptom Drug Enzyme Compound   Target Concepts: Gene/Protein Disease Symptom Drug Enzyme Compound

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Query: EC:2.7.11.10 (IKK)
4,900 document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .

Human Gene/Protein IKK 2478 IkappaB kinase 1468 TBK1 766 p65 755 Mol 564 cytokine 554 TNF 506 IkappaBalpha 499 tumor necrosis factor 473 interferon 422 lipopolysaccharide 348 IL-6 339 IFN 334 p38 330 Sep 321 IRF3 318 TANK-binding kinase 1 314 JNK 289 NEMO 269 ubiquitin 267 more...

Disease cancer 726 tumor 433 virus infection 215 tumorigenesis 152 breast cancer 120 leukemia 100 obesity 96 rheumatoid arthritis 85 carcinogenesis 78 diabetes 78 hepatocellular carcinoma 69 amyotrophic lateral sclerosis 67 tumor progression 64 tumor growth 57 lymphoma 55 arthritis 53 prostate cancer 53 ischemia 53 sepsis 52 type 2 diabetes 51 more...

Symptom pain 20 starvation 15 diarrhea 15 cachexia 6 hypothermia 6 fatigue 4 ataxia 3 collapse 3 vomiting 3 erythema 3 overweight 2 exhaustion 2 insomnia 2 functional recovery 2 weakness 2 nausea 2 acute stress 2 analgesia 2 splenomegaly 2 memory loss 2 more...

Drug lysine 68 IFN-beta 52 ROS 49 IL-2 42 IFN-gamma 28 MAP 28 CSF 16 TAK 13 Dermatol 13 Amlexanox 9 Parkin 9 Parkin 9 Retinoic acid 9 p75 7 Gel 6 Bortezomib 6 uPA 6 Taxol 6 Arsenic trioxide 5 Auranofin 5 more...

Enzyme IKK 4900 mitogen-activated protein kinase 725 protein kinase 269 ERK 245 proteasome 175 luciferase 157 MEK 149 protein kinase C 130 focal adhesion kinase 103 caspase-3 82 MEKK1 81 NO synthase 64 phosphatidylinositol 3-kinase 62 p100 55 AMP-activated protein kinase 50 calcineurin 42 caspase-8 42 glutathione S-transferase 42 PARP 41 peroxidase 34 more...

Compound DNA 717 TNF 506 Dec 308 serine 224 oxygen 207 nitric oxide 148 lysine 105 glucose 103 tyrosine 98 threonine 87 Clin 82 MEK 74 AMP 72 acetate 69 alanine 56 sodium 54 cGMP 54 calcium 52 THP 52 cysteine 51 more...

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