Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:2.7.11.10 (IKK)
 4,900 document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
IKK 0.504
IkappaB kinase 0.291
TBK1 0.156
TANK-binding kinase 1 0.064
IKBKB 0.021
IkappaBalpha 0.019
IRF3 0.015
NEMO 0.014
IKK2 0.012
CHUK 0.010
IKK1 0.010
p65 0.008
TANK 0.008
TAK1 0.005
STING 0.005
interferon regulatory factor 3 0.004
NIK 0.004
IKK epsilon 0.004
TRAF6 0.003
RIG-I 0.003
IkappaBbeta 0.003
MAVS 0.003
TRAF2 0.003
TRAF3 0.002
MITA 0.002
IKBKE 0.002
p50 0.001
TRIF 0.001
TAB2 0.001
IRF7 0.001
type I interferon 0.001
IkappaB alpha 0.001
JNK 0.001
SINTBAD 0.001
p100 0.001
SIKE 0.001
IkappaBepsilon 0.001
CARMA1 0.001
MyD88 0.001
optineurin 0.001
TNF 0.001
AZI2 0.001
conserved helix-loop-helix ubiquitous kinase 0.001
p52 0.001
tumor necrosis factor 0.001
p38 0.001
p105 0.001
MALT1 0.001
TAB1 0.001
TGF-beta-activated kinase 1 0.001
Ubc13 0.001
TLR4 0.001
interferon 0.001
LMBR1 0.001
MEKK3 0.001
IP1 0.001
MDA5 0.001
OPTN 0.001
TLR3 0.001
NFKBIA 0.001
IFN 0.001
TAX1BP1 0.001
Optineurin 0.001
NDP52 0.000
LPS 0.000
IKBKA 0.000
inducible nitric oxide synthase 0.000
IRAK-1 0.000
ubiquitin 0.000
A20 0.000
CYLD 0.000
cytokine 0.000
TAB3 0.000
transforming growth factor-beta-activated kinase 1 0.000
NAK-associated protein 1 0.000
RIP1 0.000
IL-6 0.000
lipopolysaccharide 0.000
AP-1 0.000
TRADD 0.000
MEKK1 0.000
IRAK1 0.000
IRAK4 0.000
MEKK 0.000
NLRP4 0.000
TNF receptor 0.000
CISD2 0.000
RLR 0.000
MAPK 0.000
Ubiquitin 0.000
Deltex4 0.000
TAK1-binding protein 1 0.000
cIAP2 0.000
TRAF family member-associated NF-kappa-B activator 0.000
TNF-alpha 0.000
CHCHD10 0.000
RIPK1 0.000
cyclooxygenase-2 0.000
c-Rel 0.000
NAK 0.000
DDX41 0.000
G patch domain-containing protein 3 0.000
Parkinson disease (autosomal recessive, juvenile) 2, parkin 0.000
TMEM203 0.000
peroxisomal biogenesis factor 3 0.000
FBXO18 0.000
RAS-like GTPase 0.000
IKBKB protein 0.000
transporter for antigen processing 1 0.000
IFITM2 protein 0.000
ZSWIM4 0.000
IL-8 0.000
CARD11 0.000
tumor necrosis factor alpha 0.000
IKK-interacting protein 0.000
TRIM56 0.000
RIP 0.000
TRAF5 0.000
ERK 0.000
IRF-7 0.000
VISA 0.000
proteasome 0.000
calcium binding and coiled-coil domain 2 0.000
c-Jun 0.000
TBC1D17 0.000
TRAF3 interacting protein 2 0.000
TXBP151 0.000
IFI16 0.000
RALB 0.000
mitogen-activated protein kinase kinase kinase 3 0.000
adaptor protein 0.000
tumor necrosis factor receptor 0.000
CARMA3 0.000
UBQLN2 0.000
BCL10 0.000
ISG56 0.000
zinc finger protein 268 0.000
LMTK2 protein 0.000
TBC1 domain family member 15 0.000
ZDHHC11 0.000
ankyrin repeat and SOCS box-containing 8 0.000
TBC1 domain family member 9 0.000
EID-2-like inhibitor of differentiation-3 0.000
G1/S-specific cyclin E2 0.000
TANK protein 0.000
ASB8 0.000
coilin-interacting nuclear ATPase protein 0.000
ADCK2 0.000
ubiquitin specific peptidase 10 0.000
NFkappaB essential modulator 0.000
COX-2 0.000
RELA 0.000
IFN-beta 0.000
IL-1 0.000
ABIN-2 0.000
C9orf72 0.000
TICAM1 0.000
Z-DNA binding protein 1 0.000
MAP3K14 0.000
ZF7 0.000
more...
Disease
CYLD 0.001
Sendai virus infection 0.000
VISA 0.000
virus infection 0.000
incontinentia pigmenti 0.000
cancer 0.000
tumorigenesis 0.000
NEK1 0.000
chronic tracheitis 0.000
EDA-ID 0.000
tumor 0.000
amyotrophic lateral sclerosis 0.000
ectodermal dysplasia 0.000
ABC-DLBCL 0.000
Spring viremia of carp 0.000
rheumatoid arthritis 0.000
Aortic calcification 0.000
adult T-cell leukemia/lymphoma 0.000
stomatitis 0.000
FUS 0.000
MODY4 0.000
leukemia 0.000
tumor progression 0.000
Escherichia coli pneumonia 0.000
Hypertensive retinopathy 0.000
Hypertensive retinopathy 0.000
carcinogenesis 0.000
Blocking 0.000
breast cancer 0.000
B-cell lymphoma 0.000
colitis 0.000
SPG11 0.000
EBSS 0.000
viral keratitis 0.000
Primary effusion lymphoma 0.000
obesity 0.000
NOD 0.000
hepatocellular carcinoma 0.000
FTD-ALS 0.000
bacterial infection 0.000
Gram-positive bacterial infection 0.000
herpes simplex 0.000
Cytokine storm 0.000
Epithelioma 0.000
viral arthritis 0.000
tumor growth 0.000
Papillary renal cell carcinoma 0.000
Frontotemporal dementia 0.000
AA1 0.000
prostate cancer 0.000
Other variants 0.000
MCF 0.000
sepsis 0.000
sepsis 0.000
type 2 diabetes 0.000
Kaposi's sarcoma 0.000
Lumbar disc herniation 0.000
MIP 0.000
pancreatic cancer 0.000
lymphoma 0.000
arthritis 0.000
low tension glaucoma 0.000
Cutaneous lupus erythematosus 0.000
multiple myeloma 0.000
dermatitis 0.000
NS3 0.000
Herpes simplex encephalitis 0.000
FTLD 0.000
Splenic marginal zone lymphoma 0.000
influenza 0.000
Vesicular stomatitis 0.000
ATM 0.000
immunodeficiency 0.000
Advanced cancer 0.000
inflammatory bowel disease 0.000
Meconium aspiration syndrome 0.000
familial dysautonomia 0.000
melanoma 0.000
herpangina 0.000
atherosclerosis 0.000
hepatitis C 0.000
skin tumor 0.000
Oral infection 0.000
molluscum contagiosum 0.000
ischemia 0.000
Recruitment 0.000
ALS2 0.000
ocular herpes 0.000
PLAT 0.000
acute gastritis 0.000
Chronic gastritis 0.000
Cancer cachexia 0.000
early disease onset 0.000
CCL 0.000
Epstein 0.000
mucosa-associated lymphoid tissue 0.000
vaccinia 0.000
lung cancer 0.000
GSH 0.000
dementia 0.000
Psoriasis vulgaris 0.000
endotoxic shock 0.000
osteoarthritis 0.000
DSS 0.000
salivary gland cancer 0.000
lymphoblastoma 0.000
ISD 0.000
Primary open-angle glaucoma 0.000
Borna disease 0.000
osteopoikilosis 0.000
colon cancer 0.000
overnutrition 0.000
chondrosarcoma 0.000
osteopetrosis 0.000
diabetes 0.000
Hodgkin's disease 0.000
sandfly fever 0.000
HNSCC 0.000
SCD 0.000
FANCI 0.000
autoimmune disease 0.000
hyperglycemia 0.000
XFS 0.000
infectious diseases 0.000
DSS 0.000
ovarian cancer 0.000
skin cancer 0.000
Primary immunodeficiency 0.000
African swine fever 0.000
US1 0.000
DRM 0.000
Lequesne 0.000
X-linked lymphoproliferative syndrome 0.000
viremia 0.000
Middle cerebral artery occlusion 0.000
latent infection 0.000
cerebral ischemia 0.000
asthma 0.000
primary lateral sclerosis 0.000
HOPS 0.000
Tumour necrosis 0.000
chronic obstructive pulmonary disease 0.000
orf 0.000
EDA 0.000
encephalomyelitis 0.000
multicentric Castleman's disease 0.000
immune deficiency 0.000
RSV infection 0.000
Mycobacterium 0.000
liver cancer 0.000
gastritis 0.000
hypogammaglobulinemia 0.000
adenocarcinoma 0.000
liver cancer 0.000
Newcastle disease 0.000
inflammatory joint disease 0.000
liver infection 0.000
B-cell neoplasm 0.000
B-cell lymphomas 0.000
Huntington's disease 0.000
more...
Symptom
impaired motor coordination 0.000
bradypnea 0.000
starvation 0.000
Scratch 0.000
cachexia 0.000
Decreased activity 0.000
swollen joints 0.000
diarrhea 0.000
productive cough 0.000
hypothermia 0.000
Neuropathic pain 0.000
memory loss 0.000
menopausal symptoms 0.000
acute stress 0.000
hyperoxia 0.000
pain 0.000
dysuria 0.000
polyuria 0.000
cancer pain 0.000
bone pain 0.000
erythema 0.000
cerebellar ataxia 0.000
ataxia 0.000
apathy 0.000
splenomegaly 0.000
insomnia 0.000
paresthesia 0.000
hepatomegaly 0.000
paresis 0.000
hypotonia 0.000
functional recovery 0.000
exhaustion 0.000
collapse 0.000
arthralgia 0.000
hypercapnia 0.000
vomiting 0.000
fatigue 0.000
dizziness 0.000
nausea 0.000
overweight 0.000
analgesia 0.000
anorexia 0.000
weakness 0.000
angina 0.000
cough 0.000
seizures 0.000
anesthesia 0.000
Drug
Amlexanox 0.000
IFN-beta 0.000
Pelubiprofen 0.000
Ertiprotafib 0.000
TAK 0.000
ROS 0.000
Auranofin 0.000
E5564 0.000
Myotrophin 0.000
lysine 0.000
IL-2 0.000
RAL 0.000
Radicicol 0.000
Parkin 0.000
MAP 0.000
Parkin 0.000
Vesnarinone 0.000
Ciglitazone 0.000
Glybenclamide 0.000
Compound 16 0.000
Fluticasone propionate 0.000
Red ginseng 0.000
Ginger 0.000
Bortezomib 0.000
NAH 0.000
Retinoic acid 0.000
IFN-gamma 0.000
Salicylate 0.000
Arsenic trioxide 0.000
CCL 0.000
Febuxostat 0.000
Vinpocetine 0.000
Darunavir 0.000
Dasatinib 0.000
Artesunate 0.000
Rebamipide 0.000
Rasagiline 0.000
Nitazoxanide 0.000
3-Methyladenine 0.000
uPA 0.000
BLyS 0.000
Glycyrrhiza 0.000
p75 0.000
Taxol 0.000
IL-11 0.000
ID2 0.000
Myricetin 0.000
K-252a 0.000
CIA 0.000
Fulvestrant 0.000
Rosiglitazone 0.000
Imatinib 0.000
Simvastatin 0.000
CSF 0.000
Epigallocatechin 0.000
Moxifloxacin 0.000
Emodin 0.000
Heme 0.000
Dihydro 0.000
Gefitinib 0.000
Troglitazone 0.000
Papain 0.000
GHRP 0.000
Emodin 0.000
CPM 0.000
TAT 0.000
Taxotere 0.000
Budesonide 0.000
R1881 0.000
Kainic acid 0.000
Alanine 0.000
Ginseng 0.000
Gelatin 0.000
TEL 0.000
Docetaxel 0.000
Fructose 0.000
APD 0.000
DEX 0.000
Herceptin 0.000
Acyclovir 0.000
CTC 0.000
Doxycycline 0.000
ETS 0.000
Gel 0.000
RFP 0.000
Azithromycin 0.000
ALA 0.000
Angiotensin II 0.000
Fentanyl 0.000
CTC 0.000
Glutathione 0.000
IL-1ra 0.000
CTA 0.000
Gleevec 0.000
IPM 0.000
MRC 0.000
balanced salt solution 0.000
Fluorescein 0.000
Award 0.000
Norplant 0.000
Bevacizumab 0.000
TTC 0.000
Itraconazole 0.000
Propofol 0.000
Captopril 0.000
G-CSF 0.000
pyridoxal phosphate 0.000
ascorbate 0.000
Fraction 0.000
Nitric Oxide 0.000
Alliance 0.000
vitamin E 0.000
Indomethacin 0.000
Asthma 0.000
Rituximab 0.000
Asn 0.000
Portal 0.000
Dermatol 0.000
CTX 0.000
CTX 0.000
EPA 0.000
ROC 0.000
DNase I 0.000
Monit 0.000
ABC 0.000
Ethanol 0.000
CTX 0.000
TiO2 0.000
caffeine 0.000
NADH 0.000
Cardiovasc 0.000
Enzyme
IKK 1.000
mitogen-activated protein kinase 0.001
MEKK1 0.001
p100 0.001
MEK 0.000
proteasome 0.000
protein kinase 0.000
luciferase 0.000
ERK 0.000
phosphatidylinositol 3-kinase 0.000
protein kinase C 0.000
caspase-8 0.000
NO synthase 0.000
focal adhesion kinase 0.000
phosphatidylinositol 3-phosphate 5-kinase 0.000
AMP-activated protein kinase 0.000
phosphoinositide 3-kinase 0.000
caspase-3 0.000
AMPK 0.000
HK3 0.000
PARP 0.000
MAP 0.000
calcineurin 0.000
caspase-1 0.000
GSK 0.000
NADPH oxidase 0.000
STK4 0.000
NADPH oxidase 0.000
GK2 0.000
glutathione S-transferase 0.000
AMPK 0.000
ECH 0.000
PDK1 0.000
caspase-11 0.000
caspase-11 0.000
protein phosphatase 2A 0.000
aggrecanase-1 0.000
MHCK 0.000
diaminopimelate decarboxylase 0.000
octopine dehydrogenase 0.000
choline dehydrogenase 0.000
caspase-10 0.000
MIP 0.000
ubiquitin-protein ligase 0.000
methylcrotonyl-CoA carboxylase 0.000
polo-like kinase 1 0.000
caspase-9 0.000
GalT 0.000
7-dehydrocholesterol reductase 0.000
macrophage elastase 0.000
disulfide reductase 0.000
calpain 3 0.000
glycine N-methyltransferase 0.000
phospholipase C 0.000
neutral sphingomyelinase 0.000
type 1 protein phosphatase 0.000
mu-calpain 0.000
NQO1 0.000
caspase-10 0.000
sphingosine kinase 0.000
GD3 synthase 0.000
urokinase-type plasminogen activator 0.000
heme oxygenase 0.000
STK11 0.000
peroxidase 0.000
catalase 0.000
GRK2 0.000
3C protease 0.000
myosin light chain kinase 0.000
TOR 0.000
superoxide dismutase 0.000
meprin 0.000
HK2 0.000
lysyl hydroxylase 0.000
MMP-3 0.000
collagenase 0.000
dimethylarginine dimethylaminohydrolase 0.000
CaMKII 0.000
ceramidase 0.000
caspase-2 0.000
TACE 0.000
gamma-glutamylcysteine synthetase 0.000
NOS 0.000
caspase-2 0.000
guanylate kinase 0.000
thioredoxin reductase 0.000
caspase-7 0.000
caspase-7 0.000
cdc2 0.000
Protein 2 0.000
calpain 3 0.000
histone acetyltransferase 0.000
CGT 0.000
caspase-6 0.000
glucosylceramide synthase 0.000
BAL 0.000
caspase-6 0.000
O-GlcNAc transferase 0.000
phosphoribulokinase 0.000
CYP27A1 0.000
chaperonin 0.000
matrix metalloproteinase 9 0.000
thromboxane synthase 0.000
myrosinase 0.000
PI-PLC 0.000
matrix metalloproteinase 2 0.000
TAT 0.000
glutathione peroxidase 0.000
factor C 0.000
GTP cyclohydrolase I 0.000
chalcone synthase 0.000
AST 0.000
CPM 0.000
phosphatidylinositol 4-kinase 0.000
firefly luciferase 0.000
lipoxygenase 0.000
RNA polymerase 0.000
papain 0.000
alanine aminotransferase 0.000
phosphoenolpyruvate carboxykinase 0.000
topoisomerase 0.000
cytosine deaminase 0.000
creatine kinase 0.000
AGT 0.000
peptidyl-prolyl cis-trans isomerase 0.000
thrombin 0.000
prolyl hydroxylase 0.000
topoisomerase 0.000
aldose reductase 0.000
MPP 0.000
lysozyme 0.000
12-lipoxygenase 0.000
aspartate aminotransferase 0.000
beta-secretase 0.000
arginase 0.000
adenosine kinase 0.000
interstitial collagenase 0.000
complex I 0.000
farnesyltransferase 0.000
acid phosphatase 0.000
phosphoenolpyruvate carboxykinase 0.000
phosphoenolpyruvate carboxykinase 0.000
MMP 0.000
P-glycoprotein 0.000
PKG 0.000
3-hydroxy-3-methylglutaryl-CoA reductase 0.000
RNase 0.000
GRK5 0.000
SPC 0.000
15-lipoxygenase 0.000
phosphodiesterase 0.000
MDP 0.000
TSA 0.000
reverse transcriptase 0.000
acetyl-CoA carboxylase 0.000
succinate dehydrogenase 0.000
RNase 0.000
xanthine oxidase 0.000
glucose-6-phosphatase 0.000
PGM 0.000
more...
Compound
TNF 0.001
C13H9ClFNO2 0.000
TPCK 0.000
serine 0.000
Wedelolactone 0.000
DNA 0.000
Robinin 0.000
Robinin 0.000
Ovatodiolide 0.000
Tylophorine 0.000
Humulone 0.000
Nodakenin 0.000
MEK 0.000
RELA 0.000
Ginkgolide C 0.000
Sulfuretin 0.000
Malabaricone C 0.000
Parthenolide 0.000
Taraxerol 0.000
Monotropein 0.000
Taraxerol 0.000
Miltirone 0.000
Celastrol 0.000
DuP 697 0.000
1H-imidazole 0.000
Parthenolide 0.000
THP 0.000
THP 0.000
PGE 0.000
Pachymic acid 0.000
Ginkgolide C 0.000
nitric oxide 0.000
Humulone 0.000
Prunetin 0.000
Deoxyelephantopin 0.000
Dihydromyricetin 0.000
Isovitexin 0.000
celastrol 0.000
threonine 0.000
Sarsasapogenin 0.000
PMA 0.000
Ginsenoside Re 0.000
Gramine 0.000
Curcumin 0.000
Magnoflorine 0.000
Eupatilin 0.000
Psoralidin 0.000
cGMP 0.000
4-Thiouridine 0.000
Withaferin A 0.000
lysine 0.000
Guggulsterone 0.000
Falcarindiol 0.000
Arctiin 0.000
AMP 0.000
Gambogic acid 0.000
2,6-dichloropyridine 0.000
Swertiamarin 0.000
Fangchinoline 0.000
oxygen 0.000
PMA 0.000
Boswellic acid 0.000
Butein 0.000
pyrrolidine 0.000
Carnosic acid 0.000
tyrosine 0.000
Iturin A 0.000
pyrrolidine 0.000
CUE 0.000
N-acetylcysteine 0.000
MAP 0.000
Poly(I:C) 0.000
Chrysin 0.000
Ginkgolide B 0.000
Benznidazole 0.000
Benznidazole 0.000
Benznidazole 0.000
Daphnetin 0.000
ATF 0.000
EPC 0.000
Pristimerin 0.000
Pristimerin 0.000
Pristimerin 0.000
Flavone acetic acid 0.000
Pristimerin 0.000
Phosphatidylinositol 0.000
PRD 0.000
Digitoxin 0.000
Alantolactone 0.000
Lipoxin A4 0.000
HFr 0.000
MDA 0.000
Bergenin 0.000
3-cyanopyridine 0.000
Poly I 0.000
Ubiquitin 0.000
Diosmetin 0.000
ASC 0.000
Acacetin 0.000
Carnosol 0.000
Cryptoxanthin 0.000
Surfactin 0.000
Arsenite 0.000
1-heptene 0.000
pentyl acetate 0.000
Garcinol 0.000
thieno[2,3-b]pyridine 0.000
Glabridin 0.000
4-hydroxy-3-methoxybenzaldehyde 0.000
4-hydroxy-3-methoxybenzaldehyde 0.000
Luteolin 0.000
Tangeretin 0.000
GMP 0.000
Manumycin 0.000
Zingerone 0.000
9Z,11E-octadecadienoic acid 0.000
PGE2 0.000
Pinocembrin 0.000
Deguelin 0.000
Piceatannol 0.000
Pterostilbene 0.000
Mimosine 0.000
Apigenin 0.000
cephalotaxine 0.000
Salina 0.000
alanine 0.000
3-aminobenzoic acid 0.000
Mimosine 0.000
Dec 0.000
Punicalagin 0.000
cephalotaxine 0.000
Sterigmatocystin 0.000
PGJ2 0.000
Noscapine 0.000
Emetine 0.000
acetate 0.000
(S)-4-carboxyphenylglycine 0.000
Tyrosol 0.000
chalcone 0.000
4-hydroxy-3-methoxybenzaldehyde 0.000
DMU 0.000
DMU 0.000
Mangiferin 0.000
Rottlerin 0.000
Caffeic acid phenethyl ester 0.000
DMSP 0.000
NIX 0.000
Serine 0.000
glucose 0.000
cysteine 0.000
DFD 0.000
Geldanamycin 0.000
Sulfasalazine 0.000
Cinnamaldehyde 0.000
CeCl3 0.000
Fenvalerate 0.000
Ethyl pyruvate 0.000
Rottlerin 0.000
Embelin 0.000
Phenethyl isothiocyanate 0.000
more...