Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: EC:2.7.11.1 (
protein kinase
)
81,284
document(s) hit in 31,850,051 MEDLINE articles (0.06 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
PKA
0.084
cAMP-dependent protein kinase
0.075
cyclin-dependent kinase
0.068
serine/threonine protein kinase
0.022
PKG
0.021
casein kinase
0.016
Raf-1
0.014
calmodulin
0.011
CK2
0.010
PKC
0.007
AMP
0.007
cyclin
0.007
GSK
0.007
PKR
0.006
PKI
0.005
serine kinase
0.004
adenylyl cyclase
0.004
threonine
0.004
protein kinase inhibitor
0.004
protein phosphatase
0.003
phosphorylating
0.003
p38
0.003
ERK1
0.003
phosphatase
0.003
ATP
0.003
MEK
0.003
adenylate cyclase
0.003
Protein kinase
0.003
CREB
0.003
A-kinase anchoring protein
0.002
protein kinase B
0.002
CaMKII
0.002
MAPK
0.002
ERK
0.002
p27
0.002
phosphodiesterase
0.002
phosphoprotein
0.002
mitogen-activated protein
0.002
p21
0.002
MAP kinase
0.002
Mol
0.002
phosphatidylinositol 3-kinase
0.002
extracellular signal-regulated kinase
0.002
HIPK2
0.002
c-Jun
0.002
CDK2
0.002
AKAP
0.001
serine/threonine kinase
0.001
phosvitin
0.001
cAMP response element-binding protein
0.001
phospholamban
0.001
PKB
0.001
mTOR
0.001
phosphorylase kinase
0.001
MEK1
0.001
cAMP-response element
0.001
cyclin D1
0.001
choline kinase
0.001
Rho
0.001
ERK2
0.001
cyclin E
0.001
ribosomal S6 protein kinase
0.001
protein kinase C inhibitor
0.001
AKT
0.001
PRKAR1A
0.001
tyrosine kinase
0.001
AMPK
0.001
glycogen synthase
0.001
phosphoinositide 3-kinase
0.001
CDK4
0.001
A kinase
0.001
cyclin A
0.001
cAMP response element binding protein
0.001
EPAC
0.001
GTP
0.001
insulin
0.001
casein
0.001
JNK
0.001
initiation factor 2
0.001
myosin light chain kinase
0.001
more...
Disease
retinoblastoma
0.001
cancer
0.001
pertussis
0.000
tumor
0.000
Alzheimer's disease
0.000
tumorigenesis
0.000
ATM
0.000
neuroblastoma
0.000
Rous sarcoma
0.000
cholera
0.000
PDE
0.000
breast cancer
0.000
tumor growth
0.000
hepatocellular carcinoma
0.000
ischemia
0.000
MCF
0.000
SDS
0.000
diabetes
0.000
Blocking
0.000
leukemia
0.000
type 2 diabetes
0.000
carcinogenesis
0.000
tumor progression
0.000
heart failure
0.000
DMAT
0.000
melanoma
0.000
obesity
0.000
DM1
0.000
glioma
0.000
hyperglycemia
0.000
pheochromocytoma
0.000
NAME
0.000
colon cancer
0.000
avian sarcoma
0.000
prostate cancer
0.000
acrodysostosis
0.000
carcinoma
0.000
Parkinson's disease
0.000
virus infection
0.000
herpes simplex
0.000
CLN1
0.000
vaccinia
0.000
depression
0.000
CLN2
0.000
osteosarcoma
0.000
cystic fibrosis
0.000
fatty liver
0.000
memory impairment
0.000
cerebral ischemia
0.000
APC
0.000
atherosclerosis
0.000
lung cancer
0.000
glioblastoma
0.000
colorectal cancer
0.000
polycystic kidney
0.000
lymphoma
0.000
B-cell lymphoma
0.000
tuberous sclerosis
0.000
bipolar disorder
0.000
hypertension
0.000
AIP
0.000
papillary thyroid cancer
0.000
neoplastic transformation
0.000
AIP
0.000
acute promyelocytic leukemia
0.000
adenocarcinoma
0.000
cognitive impairment
0.000
osteoblastic osteosarcoma
0.000
AGS
0.000
LTD
0.000
RGS
0.000
squamous cell carcinoma
0.000
insulinoma
0.000
diabetic cardiomyopathy
0.000
cytomegalovirus
0.000
chronic myeloid leukemia
0.000
diabetic nephropathy
0.000
ovarian cancer
0.000
stomatitis
0.000
sarcoma
0.000
more...
Symptom
starvation
0.000
rundown
0.000
pain
0.000
memory loss
0.000
collapse
0.000
functional recovery
0.000
Incisional pain
0.000
Neuropathic pain
0.000
neurological pain
0.000
seizures
0.000
ataxia
0.000
Anoxia
0.000
Inflammatory pain
0.000
Mucosal hyperplasia
0.000
Diaphragmatic weakness
0.000
Quadriceps weakness
0.000
skin damage
0.000
diarrhea
0.000
acute stress
0.000
hyperoxia
0.000
Scratch
0.000
Mechanical pain
0.000
cerebellar ataxia
0.000
cachexia
0.000
breast hyperplasia
0.000
analgesia
0.000
exhaustion
0.000
polyuria
0.000
acute pain
0.000
hypothermia
0.000
Crushing
0.000
fatigue
0.000
Pain symptoms
0.000
ACHE
0.000
Organ failure
0.000
despair
0.000
Catch
0.000
Lower urinary tract symptoms
0.000
weakness
0.000
impaired motor coordination
0.000
anesthesia
0.000
Excitable
0.000
Fluctuation
0.000
trigeminy
0.000
respiratory distress
0.000
disturbed balance
0.000
blemishes
0.000
hypercapnia
0.000
stigma
0.000
infant diarrhea
0.000
Spots
0.000
acidity
0.000
HSA
0.000
female puberty
0.000
astasia
0.000
anorexia
0.000
POA
0.000
bradykinesia
0.000
splenomegaly
0.000
bitter taste
0.000
masculinization
0.000
overweight
0.000
polydipsia
0.000
skin irritant
0.000
hypotonia
0.000
incoordination
0.000
Noise-induced hearing loss
0.000
stomach pain
0.000
tremor
0.000
hepatomegaly
0.000
neurological disability
0.000
Decreased activity
0.000
hunger
0.000
prostatism
0.000
dry eye
0.000
decreased appetite
0.000
forgetfulness
0.000
muscle stiffness
0.000
thinning
0.000
autodigestion
0.000
more...
Drug
Forskolin
0.002
K-252a
0.000
MAP
0.000
Glucagon
0.000
Flavopiridol
0.000
Rolipram
0.000
lysine
0.000
ICI
0.000
PTH
0.000
caffeine
0.000
Balanol
0.000
ROS
0.000
DM1
0.000
Cilostazol
0.000
Sorafenib
0.000
Gel
0.000
Radicicol
0.000
Angiotensin II
0.000
Butaprost
0.000
IFN-gamma
0.000
Histamine
0.000
Asn
0.000
Parkin
0.000
Parkin
0.000
IL-2
0.000
Sodium nitroprusside
0.000
IFN-beta
0.000
Imatinib
0.000
Gleevec
0.000
Liraglutide
0.000
Ethanol
0.000
Alsterpaullone
0.000
Emodin
0.000
Acadesine
0.000
Purvalanol
0.000
K506
0.000
2-Fluoroadenosine
0.000
Indolidan
0.000
Nitric Oxide
0.000
Carperitide
0.000
Nexavar
0.000
Retinoic acid
0.000
Emodin
0.000
GHRP
0.000
Trifluoperazine
0.000
Nephron
0.000
Edotecarin
0.000
Doramapimod
0.000
Secretin
0.000
Activin
0.000
Roflumilast
0.000
Roflumilast
0.000
Hymenialdisine
0.000
Phosphatidylserine
0.000
Gefitinib
0.000
p75
0.000
Iloprost
0.000
Parotin
0.000
CaCl2
0.000
CaCl2
0.000
CaCl2
0.000
Alanine
0.000
EE2
0.000
Arsenic trioxide
0.000
Taxol
0.000
AC2
0.000
Montirelin
0.000
Trodusquemine
0.000
IL-11
0.000
Olomoucine
0.000
GRF
0.000
Fructose
0.000
TAK
0.000
Estrogens
0.000
Pyrethrum extract
0.000
1-Aminoethyl
0.000
Xaliproden
0.000
Heme
0.000
Exenatide
0.000
Lobucavir
0.000
more...
Enzyme
protein kinase
1.000
AMPK
0.047
PKG
0.021
protein kinase C
0.021
mitogen-activated protein kinase
0.010
GSK
0.007
CaMKII
0.005
calcineurin
0.004
MEK
0.004
cdc2
0.003
adenylate cyclase
0.003
phosphodiesterase
0.002
phosphatidylinositol 3-kinase
0.002
AMP-activated protein kinase
0.002
phosphorylase kinase
0.001
guanylate cyclase
0.001
ERK
0.001
AMPK
0.001
phospholipase C
0.001
myosin light chain kinase
0.001
protein phosphatase 2A
0.001
phosphoinositide 3-kinase
0.001
MEKK1
0.001
focal adhesion kinase
0.000
caspase-3
0.000
hormone-sensitive lipase
0.000
PDK1
0.000
phosphorylase
0.000
polo-like kinase 1
0.000
PDE
0.000
proteasome
0.000
ATPase
0.000
acetyl-CoA carboxylase
0.000
luciferase
0.000
MAP
0.000
CPT
0.000
CPT
0.000
CPT
0.000
NO synthase
0.000
IKK
0.000
TOR
0.000
GRK5
0.000
6-phosphofructo-2-kinase
0.000
tyrosine hydroxylase
0.000
CLK1
0.000
GRK2
0.000
RNA polymerase
0.000
NADPH oxidase
0.000
NADPH oxidase
0.000
eEF2 kinase
0.000
type 1 protein phosphatase
0.000
glutathione S-transferase
0.000
phosphoenolpyruvate carboxykinase
0.000
phosphoenolpyruvate carboxykinase
0.000
alkaline phosphatase
0.000
phosphoenolpyruvate carboxykinase
0.000
PARP
0.000
fructose-2,6-bisphosphatase
0.000
phospholipase D
0.000
phospholipase A2
0.000
caspase-9
0.000
NOS
0.000
cGMP phosphodiesterase
0.000
CTD kinase
0.000
trypsin
0.000
inositol 3-kinase
0.000
AMP-activated kinase
0.000
pyruvate kinase
0.000
thrombin
0.000
caspase-8
0.000
chloramphenicol acetyltransferase
0.000
rhodopsin kinase
0.000
cholesterol esterase
0.000
phosphatidylinositol 4-kinase
0.000
MHCK
0.000
phosphatidylinositol-4,5-bisphosphate 3-kinase
0.000
superoxide dismutase
0.000
phosphoenolpyruvate carboxylase
0.000
trehalase
0.000
glucose-6-phosphatase
0.000
more...
Compound
cAMP
0.039
AMP
0.008
serine
0.005
cGMP
0.005
threonine
0.005
calcium
0.003
ATP
0.003
MEK
0.002
tyrosine
0.002
Forskolin
0.002
adenylate
0.001
phosphoserine
0.001
8-Br-cGMP
0.001
GTP
0.001
Casein
0.001
acetate
0.001
DNA
0.001
phosphate
0.001
2-methylpiperazine
0.001
Glycogen synthase
0.001
glucose
0.001
nitric oxide
0.001
alanine
0.000
Staurosporine
0.000
PMA
0.000
Staurosporine
0.000
PMA
0.000
sodium
0.000
GMP
0.000
DEAE
0.000
Phorbol
0.000
arginine
0.000
Mg2+
0.000
PGE
0.000
Serine
0.000
CPT
0.000
glutamate
0.000
Okadaic acid
0.000
CPT
0.000
GF 109203X
0.000
Dec
0.000
COS
0.000
oxygen
0.000
MAP
0.000
TPA
0.000
Insulin
0.000
AICAR
0.000
TPA
0.000
isoquinoline
0.000
NMDA
0.000
AMPA
0.000
ADP
0.000
lysine
0.000
ADP
0.000
ADP
0.000
Wortmannin
0.000
Phorbol 12-myristate 13-acetate
0.000
AICAR
0.000
Asp
0.000
Rapamycin
0.000
Phosphatidylinositol
0.000
ATF
0.000
PGE2
0.000
leucine
0.000
5-chloroisoquinoline
0.000
SDS
0.000
Adenosine
0.000
GDP
0.000
Phosphoserine
0.000
Glucagon
0.000
TNF
0.000
Isoproterenol
0.000
Calyculin A
0.000
Metformin
0.000
glycerol
0.000
Metformin
0.000
Genistein
0.000
proline
0.000
potassium
0.000
cysteine
0.000
more...