Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:2.7.11.1 (protein kinase)
81,284 document(s) hit in 31,850,051 MEDLINE articles (0.06 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
Mol 9771
PKA 7170
cAMP-dependent protein kinase 6110
Sep 5579
ATP 5558
cyclin-dependent kinase 5526
AMP 4657
calmodulin 4655
insulin 3614
PKC 2823
threonine 2769
p38 2649
phosphatase 2575
cyclin 2417
MAPK 2416
ERK1 2317
Raf-1 2269
ERK 2153
PKG 2086
adenylate cyclase 1999
p21 1826
GSK 1802
serine/threonine protein kinase 1789
p53 1789
phosphodiesterase 1750
adenylyl cyclase 1703
MEK 1702
tyrosine kinase 1672
mTOR 1578
cytokine 1537
endoplasmic reticulum 1527
caspase-3 1371
protein phosphatase 1363
AKT 1331
GTP 1324
CK2 1323
mitogen-activated protein 1321
extracellular signal-regulated kinase 1307
phosphatidylinositol 3-kinase 1279
casein kinase 1261
more...
Disease
cancer 6994
tumor 5111
Alzheimer's disease 1533
diabetes 1509
breast cancer 1289
tumorigenesis 1098
ischemia 924
pertussis 867
hepatocellular carcinoma 839
obesity 834
retinoblastoma 825
carcinoma 823
leukemia 802
depression 775
tumor growth 765
heart failure 673
SDS 653
carcinogenesis 645
melanoma 628
type 2 diabetes 619
hypertension 602
neuroblastoma 584
prostate cancer 523
ATM 512
Parkinson's disease 507
tumor progression 507
MCF 503
cholera 498
atherosclerosis 453
virus infection 443
lung cancer 428
lymphoma 421
glioma 407
hyperglycemia 397
HIV 383
colon cancer 382
adenocarcinoma 365
colorectal cancer 363
stroke 360
cold 343
more...
Symptom
pain 609
starvation 546
seizures 147
collapse 118
diarrhea 93
functional recovery 72
anesthesia 70
ataxia 63
fatigue 60
analgesia 53
rundown 48
memory loss 42
weakness 41
exhaustion 35
hypothermia 35
respiratory distress 27
hyperoxia 25
acute stress 25
overweight 24
cachexia 24
acidity 22
stigma 21
anorexia 20
Neuropathic pain 20
cerebellar ataxia 19
vomiting 18
tremor 17
acute pain 17
hypercapnia 16
splenomegaly 15
polyuria 15
skin damage 15
headache 12
angina 11
nausea 11
thinning 11
erythema 11
Anoxia 10
constipation 10
hypotonia 10
more...
Drug
Forskolin 638
lysine 609
MAP 465
caffeine 297
ROS 278
IFN-gamma 239
Cardiovasc 235
IL-2 223
Gel 194
Dermatol 185
PTH 173
Glucagon 172
ICI 168
Asn 145
Nephron 119
K-252a 109
Angiotensin II 107
Ethanol 106
CSF 105
Histamine 101
NADH 80
EE2 70
DM1 70
IFN-beta 69
CaCl2 65
CaCl2 64
CaCl2 64
Sorafenib 62
Imatinib 61
ascorbate 59
Parkin 56
Rolipram 56
Parkin 56
Retinoic acid 55
DNase I 54
p75 51
Nitric Oxide 49
vitamin E 46
Gleevec 45
Indomethacin 44
more...
Enzyme
protein kinase 81284
protein kinase C 9214
mitogen-activated protein kinase 8941
AMPK 6885
ERK 3041
MEK 2472
calcineurin 2414
adenylate cyclase 2106
PKG 2085
GSK 1908
phosphodiesterase 1759
cdc2 1494
ATPase 1287
AMP-activated protein kinase 1285
phosphatidylinositol 3-kinase 1283
CaMKII 1236
focal adhesion kinase 1235
phospholipase C 1182
caspase-3 1071
guanylate cyclase 911
luciferase 894
proteasome 855
AMPK 697
phosphoinositide 3-kinase 644
alkaline phosphatase 613
RNA polymerase 570
NO synthase 498
protein phosphatase 2A 472
superoxide dismutase 453
myosin light chain kinase 448
trypsin 446
glutathione S-transferase 437
phosphorylase 399
MAP 388
tyrosine hydroxylase 384
thrombin 372
catalase 344
NADPH oxidase 322
PARP 314
PDE 313
more...
Compound
cAMP 13554
calcium 9629
DNA 6868
Dec 5957
ATP 5560
serine 5397
AMP 5147
threonine 4272
tyrosine 4030
glucose 3625
phosphate 3047
cGMP 3023
acetate 2620
sodium 2519
oxygen 2456
nitric oxide 2019
alanine 1679
MEK 1480
arginine 1444
GTP 1328
water 1214
Clin 1178
glutamate 1163
lysine 972
sulfate 817
potassium 815
salt 795
Mg2+ 784
adenylate 773
leucine 757
ADP 710
cysteine 698
SDS 697
TNF 696
hydrogen 683
ADP 661
ADP 659
Forskolin 639
Insulin 636
His 625
more...