Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: EC:2.7.11.1 (
protein kinase
)
81,284
document(s) hit in 31,850,051 MEDLINE articles (0.06 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
Mol
9771
PKA
7170
cAMP-dependent protein kinase
6110
Sep
5579
ATP
5558
cyclin-dependent kinase
5526
AMP
4657
calmodulin
4655
insulin
3614
PKC
2823
threonine
2769
p38
2649
phosphatase
2575
cyclin
2417
MAPK
2416
ERK1
2317
Raf-1
2269
ERK
2153
PKG
2086
adenylate cyclase
1999
more...
Disease
cancer
6994
tumor
5111
Alzheimer's disease
1533
diabetes
1509
breast cancer
1289
tumorigenesis
1098
ischemia
924
pertussis
867
hepatocellular carcinoma
839
obesity
834
retinoblastoma
825
carcinoma
823
leukemia
802
depression
775
tumor growth
765
heart failure
673
SDS
653
carcinogenesis
645
melanoma
628
type 2 diabetes
619
more...
Symptom
pain
609
starvation
546
seizures
147
collapse
118
diarrhea
93
functional recovery
72
anesthesia
70
ataxia
63
fatigue
60
analgesia
53
rundown
48
memory loss
42
weakness
41
exhaustion
35
hypothermia
35
respiratory distress
27
hyperoxia
25
acute stress
25
cachexia
24
overweight
24
more...
Drug
Forskolin
638
lysine
609
MAP
465
caffeine
297
ROS
278
IFN-gamma
239
Cardiovasc
235
IL-2
223
Gel
194
Dermatol
185
PTH
173
Glucagon
172
ICI
168
Asn
145
Nephron
119
K-252a
109
Angiotensin II
107
Ethanol
106
CSF
105
Histamine
101
more...
Enzyme
protein kinase
81284
protein kinase C
9214
mitogen-activated protein kinase
8941
AMPK
6885
ERK
3041
MEK
2472
calcineurin
2414
adenylate cyclase
2106
PKG
2085
GSK
1908
phosphodiesterase
1759
cdc2
1494
ATPase
1287
AMP-activated protein kinase
1285
phosphatidylinositol 3-kinase
1283
CaMKII
1236
focal adhesion kinase
1235
phospholipase C
1182
caspase-3
1071
guanylate cyclase
911
more...
Compound
cAMP
13554
calcium
9629
DNA
6868
Dec
5957
ATP
5560
serine
5397
AMP
5147
threonine
4272
tyrosine
4030
glucose
3625
phosphate
3047
cGMP
3023
acetate
2620
sodium
2519
oxygen
2456
nitric oxide
2019
alanine
1679
MEK
1480
arginine
1444
GTP
1328
more...