Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:2.7.10.2 (focal adhesion kinase)
44,029 document(s) hit in 31,850,051 MEDLINE articles (0.03 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
STD 7778
JAK2 5448
focal adhesion kinase 4790
ABL 4280
BCR 3722
tyrosine kinase 3403
Mol 2948
EMT 2868
FAK 2860
Sep 2804
PKB 2642
STAT3 2190
cytokine 1785
SRM 1688
JAK1 1669
SRC 1641
AKT 1584
PI3K 1430
STAT 1322
ERK 1178
paxillin 1092
Bruton's tyrosine kinase 1077
insulin 1077
Janus kinase 2 1070
MAPK 1038
ERK1 1007
protein kinase B 978
fibronectin 976
collagen 916
STAT5 906
JAK3 837
p53 805
mTOR 788
p38 758
IL-6 747
E-cadherin 732
STAT1 691
CD4 689
Janus kinase 686
phosphatidylinositol 3-kinase 647
ABL1 610
ARG 602
caspase-3 573
lymphoid 558
interferon 550
spleen tyrosine kinase 534
TEC 530
catenin 520
Bcl-2 502
Rho 500
TNF 496
FES 493
BTK 489
IFN 488
EGFR 482
MEK 479
ATP 474
JNK 470
receptor tyrosine kinase 433
RhoA 431
ZAP-70 430
phosphatase 428
extracellular signal-regulated kinase 427
signal transducer and activator of transcription 3 425
MPL 420
c-Src 419
vascular endothelial growth factor 400
PTEN 393
erythroid 385
epidermal growth factor receptor 381
BCR-ABL1 379
vinculin 373
vimentin 371
phosphoinositide 3-kinase 352
PKC 348
FPS 347
CML 345
TYK2 344
NMR 335
CD34 329
more...
Disease
STD 7780
cancer 7623
AIDS 6379
tumor 5148
ABL 4280
HIV 3413
chronic myeloid leukemia 3051
EMT 2868
leukemia 2083
breast cancer 1457
myeloproliferative disorders 1008
tumor growth 962
tumorigenesis 895
tumor progression 849
polycythemia vera 834
acute lymphoblastic leukemia 805
essential thrombocythemia 758
lymphoma 722
carcinoma 691
acute myeloid leukemia 674
Leukemia 605
myelofibrosis 589
immunodeficiency 587
primary myelofibrosis 581
syphilis 580
hepatocellular carcinoma 570
TEC 530
metastases 528
lung cancer 508
melanoma 479
prostate cancer 463
diabetes 449
chronic lymphocytic leukemia 447
Chlamydia 447
carcinogenesis 417
adenocarcinoma 409
blast crisis 394
colorectal cancer 393
chronic lymphocytic leukemia 336
obesity 324
gastric cancer 319
thrombocytosis 317
squamous cell carcinoma 316
rheumatoid arthritis 313
MCF 308
glioma 306
anemia 298
non-small cell lung cancer 268
colon cancer 268
myelodysplastic syndrome 266
multiple myeloma 262
glioblastoma 260
pancreatic cancer 254
B-cell lymphoma 248
ovarian cancer 247
minimal residual disease 244
X-linked agammaglobulinemia 235
ischemia 229
atherosclerosis 225
SCID 223
hepatitis B 222
Alzheimer's disease 221
gonococcal 214
hypertension 214
infectious diseases 212
leukemogenesis 208
tuberculosis 204
Hodgkin's disease 197
neuroblastoma 193
herpes simplex 178
cold 177
type 2 diabetes 176
ICP 176
thrombocytopenia 175
arthritis 174
depression 173
genital warts 167
cervical cancer 163
acute leukemia 163
stroke 161
more...
Symptom
splenomegaly 335
pain 204
diarrhea 124
fatigue 107
stigma 92
starvation 81
headache 52
collapse 47
abdominal pain 41
nausea 41
seizures 39
anesthesia 36
exhaustion 34
vomiting 33
functional recovery 32
respiratory distress 31
hepatosplenomegaly 30
anorexia 28
discomfort 28
urethral discharge 28
cough 26
discomfort 25
dysuria 25
dyspnea 24
overweight 23
weakness 21
acidity 18
pelvic pain 17
erythema 17
hypothermia 15
night sweats 15
tremor 14
dizziness 14
hepatomegaly 14
HSA 13
arthralgia 12
chest pain 12
nausea and vomiting 11
cachexia 10
thinning 10
hyperoxia 9
constipation 9
agitation 9
insomnia 9
Ill 9
hemiplegia 9
dry eye 8
asthenia 8
bone pain 8
acute pain 8
Scratch 7
shortness of breath 7
dystonia 7
ataxia 7
Neuropathic pain 7
abdominal discomfort 7
spasticity 7
angina 6
vertigo 6
lethargy 6
low back pain 6
analgesia 6
Fear of falling 6
cerebellar ataxia 6
Fear of falling 6
distraction 6
gumma 5
epigastric pain 5
back pain 5
muscle cramps 5
syncope 5
sore throat 4
hypercapnia 4
shoulder pain 4
tinnitus 4
hypotonia 4
myalgia 4
rales 3
neurological disability 3
paresthesia 3
more...
Drug
Imatinib 462
IL-2 268
Gleevec 258
Dasatinib 188
lysine 181
CSF 174
IFN-gamma 160
ROS 157
Dermatol 151
MAP 143
TEL 137
Monit 78
Growth hormone 70
Growth hormone 70
Leaf 55
Cardiovasc 51
MDS 51
G-CSF 42
CTX 40
ABC 38
uPA 38
Angiotensin II 38
Gel 36
GEO 36
Bosutinib 31
CTX 31
CTX 31
NVP 28
ROC 28
ETS 26
ICI 25
IL-11 24
EE2 24
MIL 23
ALA 23
EPA 22
CAM 22
Sorafenib 22
Herceptin 22
IFN-beta 21
ascorbate 21
lactose 21
MRC 20
vitamin E 20
Gefitinib 20
NADH 18
Erlotinib 18
caffeine 17
DNase I 17
Asthma 16
THF 16
Kenyan 16
CPR 15
Imiquimod 15
AZT 15
Asn 15
Lenalidomide 15
Florisil 14
AZT 14
TAT 14
ampicillin 14
Vitamin A 14
Norplant 13
Arsenic trioxide 13
citric acid 13
Taxol 12
ADM 12
Gelatin 12
Bortezomib 11
Simvastatin 11
p75 11
Cetuximab 11
Doxycycline 11
Heme 11
Nephron 11
Azithromycin 10
G418 10
Rituximab 10
niacin 10
CCL 10
more...
Enzyme
focal adhesion kinase 44029
mitogen-activated protein kinase 3173
ERK 3081
protein kinase 1235
protein kinase C 772
MEK 675
phosphatidylinositol 3-kinase 650
luciferase 446
caspase-3 422
phosphoinositide 3-kinase 353
FPS 347
GSK 247
reverse transcriptase 236
phospholipase C 227
AMP-activated protein kinase 213
proteasome 208
AMPK 199
PARP 177
AMPK 158
PDK1 148
calcineurin 148
ACS 138
alkaline phosphatase 137
thrombin 132
superoxide dismutase 130
MAP 130
glutathione S-transferase 127
NO synthase 115
ATPase 108
cdc2 106
urokinase-type plasminogen activator 105
IKK 103
RNA polymerase 98
APC 95
collagenase 93
catalase 88
alanine aminotransferase 86
MMP 86
lactate dehydrogenase 84
NADPH oxidase 78
caspase-9 75
peroxidase 72
aspartate aminotransferase 72
caspase-8 71
NADPH oxidase 66
beta-lactamase 58
renin 52
AOR 51
CD10 50
transcriptase 50
arginase 49
NOS 48
phosphodiesterase 48
ACE 44
trypsin 44
aldehyde dehydrogenase 42
protein phosphatase 2A 40
P-glycoprotein 40
STR 40
creatine kinase 35
glyceraldehyde-3-phosphate dehydrogenase 35
BMT 34
PTPase 34
DNA methyltransferase 34
myosin light chain kinase 33
glutathione peroxidase 33
CaMKII 32
MEKK1 32
aldehyde dehydrogenase 31
aldehyde dehydrogenase 29
phospholipase A2 29
caspase-1 29
aldehyde dehydrogenase 29
RNase 29
RNase 29
aldehyde dehydrogenase 29
adenylate cyclase 29
GAS 29
AST 28
topoisomerase 27
more...
Compound
tyrosine 4311
ABL 4281
BCR 3722
Dec 2878
DNA 2463
Clin 1267
oxygen 896
arginine 887
glucose 876
calcium 833
water 784
serine 600
TEC 530
TNF 496
ATP 476
MEK 472
threonine 446
MDA 420
nitric oxide 402
methionine 358
sodium 344
phosphate 324
MTT 303
hydrogen 270
lysine 270
acetate 266
cAMP 248
Tyrosine 242
cysteine 242
Insulin 236
iron 203
Phe 193
sulfate 174
alanine 173
GTP 163
leucine 161
ASA 158
PAM 151
Asp 149
zinc 145
ACS 138
ACS 138
TEL 137
His 135
Vimentin 132
MAP 130
nitrogen 126
copper 125
Gly 121
COS 119
pyrimidine 114
retinoic acid 114
pyrimidine 112
urea 109
ethanol 109
ADP 106
glutamate 104
galactose 104
TNM 103
proline 102
NH2 100
AMP 97
ammonium 97
salt 95
GSH 94
GSH 94
potassium 93
THP 90
THP 89
ADP 89
ADP 89
H2O2 88
bromide 86
Cbl 84
methanol 83
acetonitrile 82
creatinine 82
HCl 81
Ang II 79
iodine 78
more...