Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: EC:2.7.10.2 (
focal adhesion kinase
)
44,029
document(s) hit in 31,850,051 MEDLINE articles (0.03 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
STD
7778
JAK2
5448
focal adhesion kinase
4790
ABL
4280
BCR
3722
tyrosine kinase
3403
Mol
2948
EMT
2868
FAK
2860
Sep
2804
PKB
2642
STAT3
2190
cytokine
1785
SRM
1688
JAK1
1669
SRC
1641
AKT
1584
PI3K
1430
STAT
1322
ERK
1178
paxillin
1092
Bruton's tyrosine kinase
1077
insulin
1077
Janus kinase 2
1070
MAPK
1038
ERK1
1007
protein kinase B
978
fibronectin
976
collagen
916
STAT5
906
JAK3
837
p53
805
mTOR
788
p38
758
IL-6
747
E-cadherin
732
STAT1
691
CD4
689
Janus kinase
686
phosphatidylinositol 3-kinase
647
ABL1
610
ARG
602
caspase-3
573
lymphoid
558
interferon
550
spleen tyrosine kinase
534
TEC
530
catenin
520
Bcl-2
502
Rho
500
TNF
496
FES
493
BTK
489
IFN
488
EGFR
482
MEK
479
ATP
474
JNK
470
receptor tyrosine kinase
433
RhoA
431
ZAP-70
430
phosphatase
428
extracellular signal-regulated kinase
427
signal transducer and activator of transcription 3
425
MPL
420
c-Src
419
vascular endothelial growth factor
400
PTEN
393
erythroid
385
epidermal growth factor receptor
381
BCR-ABL1
379
vinculin
373
vimentin
371
phosphoinositide 3-kinase
352
PKC
348
FPS
347
CML
345
TYK2
344
NMR
335
CD34
329
more...
Disease
STD
7780
cancer
7623
AIDS
6379
tumor
5148
ABL
4280
HIV
3413
chronic myeloid leukemia
3051
EMT
2868
leukemia
2083
breast cancer
1457
myeloproliferative disorders
1008
tumor growth
962
tumorigenesis
895
tumor progression
849
polycythemia vera
834
acute lymphoblastic leukemia
805
essential thrombocythemia
758
lymphoma
722
carcinoma
691
acute myeloid leukemia
674
Leukemia
605
myelofibrosis
589
immunodeficiency
587
primary myelofibrosis
581
syphilis
580
hepatocellular carcinoma
570
TEC
530
metastases
528
lung cancer
508
melanoma
479
prostate cancer
463
diabetes
449
chronic lymphocytic leukemia
447
Chlamydia
447
carcinogenesis
417
adenocarcinoma
409
blast crisis
394
colorectal cancer
393
chronic lymphocytic leukemia
336
obesity
324
gastric cancer
319
thrombocytosis
317
squamous cell carcinoma
316
rheumatoid arthritis
313
MCF
308
glioma
306
anemia
298
non-small cell lung cancer
268
colon cancer
268
myelodysplastic syndrome
266
multiple myeloma
262
glioblastoma
260
pancreatic cancer
254
B-cell lymphoma
248
ovarian cancer
247
minimal residual disease
244
X-linked agammaglobulinemia
235
ischemia
229
atherosclerosis
225
SCID
223
hepatitis B
222
Alzheimer's disease
221
gonococcal
214
hypertension
214
infectious diseases
212
leukemogenesis
208
tuberculosis
204
Hodgkin's disease
197
neuroblastoma
193
herpes simplex
178
cold
177
type 2 diabetes
176
ICP
176
thrombocytopenia
175
arthritis
174
depression
173
genital warts
167
cervical cancer
163
acute leukemia
163
stroke
161
more...
Symptom
splenomegaly
335
pain
204
diarrhea
124
fatigue
107
stigma
92
starvation
81
headache
52
collapse
47
abdominal pain
41
nausea
41
seizures
39
anesthesia
36
exhaustion
34
vomiting
33
functional recovery
32
respiratory distress
31
hepatosplenomegaly
30
anorexia
28
discomfort
28
urethral discharge
28
cough
26
discomfort
25
dysuria
25
dyspnea
24
overweight
23
weakness
21
acidity
18
pelvic pain
17
erythema
17
hypothermia
15
night sweats
15
tremor
14
dizziness
14
hepatomegaly
14
HSA
13
arthralgia
12
chest pain
12
nausea and vomiting
11
cachexia
10
thinning
10
hyperoxia
9
constipation
9
agitation
9
insomnia
9
Ill
9
hemiplegia
9
dry eye
8
asthenia
8
bone pain
8
acute pain
8
Scratch
7
shortness of breath
7
dystonia
7
ataxia
7
Neuropathic pain
7
abdominal discomfort
7
spasticity
7
angina
6
vertigo
6
lethargy
6
low back pain
6
analgesia
6
Fear of falling
6
cerebellar ataxia
6
Fear of falling
6
distraction
6
gumma
5
epigastric pain
5
back pain
5
muscle cramps
5
syncope
5
sore throat
4
hypercapnia
4
shoulder pain
4
tinnitus
4
hypotonia
4
myalgia
4
rales
3
neurological disability
3
paresthesia
3
more...
Drug
Imatinib
462
IL-2
268
Gleevec
258
Dasatinib
188
lysine
181
CSF
174
IFN-gamma
160
ROS
157
Dermatol
151
MAP
143
TEL
137
Monit
78
Growth hormone
70
Growth hormone
70
Leaf
55
Cardiovasc
51
MDS
51
G-CSF
42
CTX
40
ABC
38
uPA
38
Angiotensin II
38
Gel
36
GEO
36
Bosutinib
31
CTX
31
CTX
31
NVP
28
ROC
28
ETS
26
ICI
25
IL-11
24
EE2
24
MIL
23
ALA
23
EPA
22
CAM
22
Sorafenib
22
Herceptin
22
IFN-beta
21
ascorbate
21
lactose
21
MRC
20
vitamin E
20
Gefitinib
20
NADH
18
Erlotinib
18
caffeine
17
DNase I
17
Asthma
16
THF
16
Kenyan
16
CPR
15
Imiquimod
15
AZT
15
Asn
15
Lenalidomide
15
Florisil
14
AZT
14
TAT
14
ampicillin
14
Vitamin A
14
Norplant
13
Arsenic trioxide
13
citric acid
13
Taxol
12
ADM
12
Gelatin
12
Bortezomib
11
Simvastatin
11
p75
11
Cetuximab
11
Doxycycline
11
Heme
11
Nephron
11
Azithromycin
10
G418
10
Rituximab
10
niacin
10
CCL
10
more...
Enzyme
focal adhesion kinase
44029
mitogen-activated protein kinase
3173
ERK
3081
protein kinase
1235
protein kinase C
772
MEK
675
phosphatidylinositol 3-kinase
650
luciferase
446
caspase-3
422
phosphoinositide 3-kinase
353
FPS
347
GSK
247
reverse transcriptase
236
phospholipase C
227
AMP-activated protein kinase
213
proteasome
208
AMPK
199
PARP
177
AMPK
158
PDK1
148
calcineurin
148
ACS
138
alkaline phosphatase
137
thrombin
132
superoxide dismutase
130
MAP
130
glutathione S-transferase
127
NO synthase
115
ATPase
108
cdc2
106
urokinase-type plasminogen activator
105
IKK
103
RNA polymerase
98
APC
95
collagenase
93
catalase
88
alanine aminotransferase
86
MMP
86
lactate dehydrogenase
84
NADPH oxidase
78
caspase-9
75
peroxidase
72
aspartate aminotransferase
72
caspase-8
71
NADPH oxidase
66
beta-lactamase
58
renin
52
AOR
51
CD10
50
transcriptase
50
arginase
49
NOS
48
phosphodiesterase
48
ACE
44
trypsin
44
aldehyde dehydrogenase
42
protein phosphatase 2A
40
P-glycoprotein
40
STR
40
creatine kinase
35
glyceraldehyde-3-phosphate dehydrogenase
35
BMT
34
PTPase
34
DNA methyltransferase
34
myosin light chain kinase
33
glutathione peroxidase
33
CaMKII
32
MEKK1
32
aldehyde dehydrogenase
31
aldehyde dehydrogenase
29
phospholipase A2
29
caspase-1
29
aldehyde dehydrogenase
29
RNase
29
RNase
29
aldehyde dehydrogenase
29
adenylate cyclase
29
GAS
29
AST
28
topoisomerase
27
more...
Compound
tyrosine
4311
ABL
4281
BCR
3722
Dec
2878
DNA
2463
Clin
1267
oxygen
896
arginine
887
glucose
876
calcium
833
water
784
serine
600
TEC
530
TNF
496
ATP
476
MEK
472
threonine
446
MDA
420
nitric oxide
402
methionine
358
sodium
344
phosphate
324
MTT
303
hydrogen
270
lysine
270
acetate
266
cAMP
248
Tyrosine
242
cysteine
242
Insulin
236
iron
203
Phe
193
sulfate
174
alanine
173
GTP
163
leucine
161
ASA
158
PAM
151
Asp
149
zinc
145
ACS
138
ACS
138
TEL
137
His
135
Vimentin
132
MAP
130
nitrogen
126
copper
125
Gly
121
COS
119
pyrimidine
114
retinoic acid
114
pyrimidine
112
urea
109
ethanol
109
ADP
106
glutamate
104
galactose
104
TNM
103
proline
102
NH2
100
AMP
97
ammonium
97
salt
95
GSH
94
GSH
94
potassium
93
THP
90
THP
89
ADP
89
ADP
89
H2O2
88
bromide
86
Cbl
84
methanol
83
acetonitrile
82
creatinine
82
HCl
81
Ang II
79
iodine
78
more...