Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:2.7.10.2 (focal adhesion kinase)
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Human Gene/Protein
synuclein, gamma 9.5
RAP1GAP protein 9.5
CHK 9.5
MRPL30 9.5
RAD21L1 9.5
CCDC107 9.5
Inositol polyphosphate-1-phosphatase 9.5
mitochondrial translation optimization 1 homolog 9.5
ZBTB22 9.5
PCDHGA10 9.5
SLK 9.5
ITK 9.5
FYN 9.5
LOC100129345 9.5
LCK 9.5
EMT 9.5
JAK3 9.5
TEC 9.5
PTK2 9.5
six-transmembrane epithelial antigen of prostate 2 9.5
FER 9.5
CCDC152 9.5
KLHL33 9.5
FYN protein 9.5
C8orf55 9.5
RBM4B 9.5
Myeloproliferative leukemia virus oncogene 9.5
C11orf45 9.5
mitogen-activated protein kinase kinase kinase kinase 2 9.5
PLOD2 protein 9.5
PCTK2 9.5
LAMB1 protein 9.5
tyrosine kinase 2 variant 9.5
SH2B3 protein 9.5
MRIP-1 9.5
focal adhesion kinase 9.5
SRM 9.5
HMGXB4 9.5
ABL1 9.5
ETK 9.5
more...
Disease
Autosomal recessive agammaglobulinemia 9.5
anemia; progressive 9.5
IMD1 9.5
MDS/MPD-U 9.5
EMT 9.5
Hereditary neutrophilia 9.5
Mumps epididymo-orchitis 9.5
genito-anorectal syndrome 9.5
TEC 9.5
ABL 9.4
STD 8.6
CMPD-U 8.5
kidney; damage 8.5
XLA2 8.5
Acute renal failure due to ischemia 8.5
Congenital agammaglobulinemia 8.5
Other anaemias 8.5
Mediastinal large B-cell lymphoma 8.5
TSC4 8.5
Plasma cell vulvitis 8.5
Sexual molestation 8.5
refractory CML 8.4
Rectal gonorrhea 8.3
male genital warts 8.2
Acquired lymphangioma 7.9
Brisket disease 7.9
esthiomene 7.9
Acute gonococcal urethritis 7.9
Syringomyelia and syringobulbia 7.9
oligocythemia 7.9
Nutritional muscular dystrophy 7.9
CORD5 7.9
hypercalcaemia due to parathyroid adenoma 7.9
X-linked agammaglobulinemia 7.9
essential thrombocytopenia 7.8
essential thrombocythemia 7.8
CML progression 7.7
chronic phase CML 7.7
Plasma cell mastitis 7.7
Ph-positive acute lymphoblastic leukemia 7.7
more...
Symptom
Genital discharge 9.5
male urethral discharge 9.5
Vulval soreness 9.5
Asynergia 8.5
Skin wetting 8.5
Factitious fever 7.9
Anal symptoms 7.5
Genital irritation 7.5
Mixed incontinence 6.5
Primary syphilis 6.1
urethral discharge 6.1
GU symptoms 6.0
Gastrointestinal distress 5.9
penile discharge 5.6
Prostatodynia 5.6
Fear of falling 5.5
Fear of falling 5.5
vaginal itching 5.4
gumma 5.3
unable to sleep 5.0
false labor 4.9
penile lesion 4.9
feeling nervous 4.9
testicular lump 4.6
splenomegaly 4.6
painful erections 4.3
vestibulitis 4.1
musculoskeletal disability 4.0
vaginal pain 3.9
Flu-like symptoms 3.7
Scratch 3.7
itchy nose 3.5
PAIN 3.4
skin pain 3.3
night sweats 3.2
lumbar back pain 3.1
Spotting 3.0
impaired motor coordination 2.9
dysuria 2.9
bewilderment 2.7
more...
Drug
Somavubove 8.2
Tikosyn 7.9
Bosutinib 7.9
Dasatinib 7.8
Lestaurtinib 7.8
Leridistim 7.5
Mudanpi 7.2
Imatinib 7.1
Gleevec 7.0
TEL 7.0
Trocade 6.9
Myvacet 6.3
Cilengitide 6.3
Kollicoat MAE 6.0
Propylene glycol alginate 5.9
Lisofylline 5.7
CCl2F2 5.6
Diphenidol 5.5
Citrus unshiu peel 5.4
Distigmine bromide 5.4
Gardenia fruit 5.3
Safingol 5.3
Olvanil 5.3
Magnesium phosphate 5.3
Ilomastat 5.3
Midostaurin 5.1
PT-141 5.0
PNT 5.0
Histoplasmin 5.0
Epothilone B 5.0
Avelox 4.9
Rayon 4.9
NOV 4.8
Berberine chloride 4.7
Podophyllotoxin 4.7
Tykerb 4.7
Hypnomidate 4.7
Photofrin II 4.6
Protein hydrolysate 4.6
Belatacept 4.6
more...
Enzyme
FPS 9.5
focal adhesion kinase 9.5
4-carboxy-2-hydroxymuconate-6-semialdehyde dehydrogenase 8.8
beta4GalNAc-T3 7.9
CobM 7.5
protocatechuate 4,5-dioxygenase 7.1
phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase 6.9
STK4 6.7
MMA(V) reductase 6.5
4-N-trimethylaminobutyraldehyde dehydrogenase 6.3
vanillin dehydrogenase 6.3
NAAT 6.0
PDK1 5.6
phosphoinositide 3-kinase 5.4
phosphatidylinositol-4,5-bisphosphate 3-kinase 5.4
phosphatidylinositol 3-kinase 5.4
galactosyltransferase I 5.3
Cypridina luciferase 5.3
tail-specific protease 5.3
inositol 3-kinase 5.2
acylcarnitine hydrolase 5.1
matrix metalloproteinase 14 5.0
MHCK 5.0
N-acetylglucosaminyltransferase V 5.0
amine transaminase 5.0
STK11 4.9
STK 4.9
MGAT 4.8
ferric chelate reductase 4.8
GalNAc4S-6ST 4.8
MEK 4.7
PurE 4.7
GSK 4.7
HK2 4.6
PTPase 4.6
arachidonate 5-lipoxygenase 4.6
mitogen-activated protein kinase 4.6
UDP-galactopyranose mutase 4.6
inositol phosphatase 4.6
ERK 4.5
more...
Compound
4-chloro-N-cyclohexylbenzamide 9.5
Bis(4-fluorophenyl)sulfone 9.5
TEC 9.5
ABL 9.0
BCR 8.7
C7H14N2O3 8.5
C7H14N2O3 8.5
C7H14N2O3 8.5
1,2,3,4,5,6-hexabromocyclohexane 8.5
C7H14N2O3 8.5
C7H14N2O3 8.5
C7H14N2O3 8.5
C7H14N2O3 8.5
C7H14N2O3 8.5
C7H14N2O3 8.5
C7H14N2O3 8.5
C7H14N2O3 8.5
C7H14N2O3 8.5
Tetraethyleneglycol dimethacrylate 8.5
C7H14N2O3 8.5
ethyl 3-hydroxy-3-phenylpropanoate 8.5
C7H14N2O3 8.5
C7H14N2O3 8.5
C7H14N2O3 8.5
C7H14N2O3 8.5
C7H14N2O3 8.5
C7H14N2O3 8.5
C7H14N2O3 8.5
C7H14N2O3 8.5
C7H14N2O3 8.5
C7H14N2O3 8.5
C7H14N2O3 8.5
C7H14N2O3 8.5
C7H14N2O3 7.9
imidazo[1,5-a]pyrazine 7.9
Chloropyramine hydrochloride 7.9
C7H14N2O3 7.9
C7H14N2O3 7.9
C7H14N2O3 7.9
C7H14N2O3 7.9
more...