Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: EC:2.7.10.2 (focal adhesion kinase)
 44,029 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)


Int J STD AIDS 1990 Sep
PMID:AIDS in the brain. 209 49


Int J STD AIDS 1990 Sep
PMID:Serological perspectives on hepatitis B and D. 209 50

Serum samples of 62 African patients who had clinical manifestations of HIV-1 infection but were seronegative for HIV-1 by ELISA (Organon) were subsequently further tested by another HIV-1 ELISA test (Wellcozyme), HIV-1 IgG Western blot, HIV-1 antigen detection and HIV-2 ELISA. Patients' lymphocytes were cultured for HIV-1 and 2. Because of limited quantities of serum available all tests were not performed on all samples. Seven (26%) of 27 sera of patients meeting the WHO clinical case definition of AIDS were Western-blot-positive. In contrast, of 35 patients' sera with possible HIV related disease, only one (3%) was Western blot positive (P = 0.02) and none of 75 sera from HIV-1 ELISA (Organon) seronegative blood donors (P less than 0.01) were Western blot positive. Of 30 HIV-1 ELISA (Organon) seronegative patients tested with the HIV-1 ELISA Wellcozyme assay only one was seropositive (this patient's serum was also Western blot positive). Of 17 HIV-1 ELISA (Organon) seronegative patients tested, HIV-1 antigen was found in 1 case (6%) (this patient's serum was Western blot negative). None of the 34 patients tested by HIV-2 serology was HIV-2 seropositive. HIV-1 was isolated by culture in 3 (21%) of 14 HIV-1 ELISA seronegative patients (sera of the 3 patients were Western blot negative). In total, 12 (19%) of 62 HIV-1 ELISA (Organon) seronegative patients were found to be positive for HIV, either by Western blot HIV antigen testing or viral culture.(ABSTRACT TRUNCATED AT 250 WORDS)
Int J STD AIDS 1990 Sep
PMID:HIV-1 infection in HIV-1 enzyme-linked immunoassay seronegative patients in Kinshasa, Zaire. 209 51

A survey of acquired immunodeficiency syndrome (AIDS)-related knowledge and attitudes was conducted during July and August 1988 in rural SW Uganda. The aim was to assess the impact of Uganda's AIDS education programme and to consider how future programmes could be more effectively implemented. Four hundred and seventy-six individuals aged 12-45 years were selected by a quota method, to form a sample stratified by age and sex. Mass AIDS education has successfully raised levels of knowledge but misconceptions persist. However, it has failed, firstly, to stress the urgency of AIDS as a personal issue, and secondly, to change negative attitudes toward people with AIDS: 57% would avoid or stigmatise an individual with AIDS. Unexpectedly, findings show that a correlation exists (P less than 0.05) between high levels of 'correct' beliefs and negative attitudes toward people with AIDS. To achieve future behavioural and attitude changes, possible ways forward for Ugandan AIDS education include involvement of HIV carriers in education, small-scale targetted approaches developed by active participation of the target group and through role playing of people with AIDS.
Int J STD AIDS 1990 Sep
PMID:AIDS education in rural Uganda--a way forward. 209 52

Two aspects of the performance of Abbott's improved Chlamydiazyme enzyme immunoassay (EIA) were studied. Firstly, the test was compared with cell culture in cervical specimens from 100 abortion applicants. The results showed good correlation between the two methods, with 12 women positive with both methods and one woman EIA-positive but culture-negative. Compared with cell culture the EIA had sensitivity of 100% and specificity of 98.9%. Secondly, the reproducibility of positive EIA tests was evaluated by re-analysing 100 consecutive positive specimens. Ninety-nine of these remained positive and one weakly positive specimen became negative. There was close correlation between absorbance values on first and second analyses. The performance of the Chlamydiazyme EIA in terms of sensitivity, specificity and reproducibility is acceptable in this patient population.
Int J STD AIDS 1990 Sep
PMID:Performance of Chlamydiazyme enzyme immunoassay for detecting Chlamydia trachomatis in cervical specimens. 209 53

Estimating the number of male prostitutes working at any given time is fraught with difficulties. We suggest that perhaps around 600-700 men were selling sex in London in 1989. We report some preliminary observations gained during the setting up of a specific service for male prostitutes. Of 32 male prostitutes seen, 26 worked as rent-boys, 4 worked through agencies and 2 worked independently from home. Forty-one per cent had evidence of at least one sexually transmissible disease and 3 of 16 men tested (19%) were human immunodeficiency virus (HIV) positive.
Int J STD AIDS 1990 Sep
PMID:Setting up a support service for male prostitutes in London. 209 54


Int J STD AIDS 1990 Sep
PMID:Epidermoid cyst of the testis. 209 55


Int J STD AIDS 1990 Sep
PMID:Sexually transmitted diseases and rape. 209 93


Int J STD AIDS 1990 Sep
PMID:Single-dose fluconazole in the treatment of Candida albicans balanoposthitis. 209 57


Int J STD AIDS 1990 Sep
PMID:Goals and objectives for STD/AIDS control into the 1990s. 209 58


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