Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:2.7.10.2 (focal adhesion kinase)
 44,029 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

IgM and IgG anti-sheep red blood cells agglutinins were measured from dayy + 2 to day + 30 in SPF mice immunized with 108 SRC and treated with 2.5 or 25 mg LMS/dg. Untreated control mice produced high levels (1:8200) of IgM-antibodies from day + 4 to day + 20. Early, day + 4, IgG-agglutinins appeared together with IgM-antibodies in mice treated with 2.5 mg LMS/kg, whereas administration of 25 mg LMS/kg induced the synthesis of antibodies belonging only to the IgG class. Titres were significantly lower (1:512) in LMS-treated mice than in controls. The switch to IgG of antibody formation is another for the ability of LMS to stimulate T cell activities.
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PMID:[Influence of levamisole on antibody production]. 84 84

Table I lists the physiological criteria for ranking each control mode (hemodynamic conditions assumed are listed in Figure 4). For each criteria, each mode was given a ranking of 0 to 3, with 3 the best. At the bottom of the table is the total of all criteria grades. The ranking from best to worst mode is in order: IND, LMA/LMS, Low FR/High FR, RMA/RMS. A discussion of Table I follows: FR is a reliable control mode and has been used extensively clinically, including the recent TAH human implants. The advantage of this mode is its simplicity: if the venous return is below pump capacity, then all incoming blood can be pumped out without any sophisticated controller. However, when the flow demand exceeds the pump capacity, HR must be increased. The ideal situation would be to set FR at one HR and %S, and leave these settings over the life of the recipient. However, a high HR like this would result in relatively high atrial pressures and low flow rates with respect to IND (as shown theoretically, in vitro, and in vivo). Although the patient would have a high maximum COR, the daily COR would be low, resulting in a relatively high AVO2 difference. Finally, FR lacks afterload sensitivity. RMA and RMS received the lowest grade of all modes. Because of the L-L shunt, the stroke length of these modes are smallest, and thus the CO curves and FPS are poorer than any other mode.(ABSTRACT TRUNCATED AT 250 WORDS)
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PMID:A mathematical model to predict the optimal control mode for a pusher-plate total artificial heart (TAH). 383 47

The Centers for Disease Control and Prevention (CDC) is looking for improved ways to collect complex, and highly sensitive, public health surveillance data. The Sexually Transmitted Diseases - Laboratory Test Methods Survey (STD-LMS) was developed to replace the traditional STD mail survey. The web-based STD-LMS offered distinct advantages over the traditional mail survey technique including,reduced time and cost of conducting the survey and avoiding the often error prone and tedious task of data entry.
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PMID:Assessing a web-based approach to collect complex and sensitive surveillance data: the sexually transmitted diseases- laboratory tests methods survey. 1677 86