Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:2.7.10.2 (focal adhesion kinase)
 44,029 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

A clinical and investigational study of 25 cases of Donovanosis was undertaken. The incidence was found to be 1.53% of all STD cases and 2.9% of GUD. M:F ratio was 2.12:1. Incidence was more in unmarried people. Fleshy exuberant type was seen in 88% of cases. Two patients (8%) had extragenital ulcers. Donovan bodies were found in 88%. Pseudo elephantiasis was seen in 8 patients. Biopsy was done in 8 cases and showed acanthosis, plasma cell infiltration and pseudo epitheliomatous hyperplasia. One patient developed squamous cell carcinoma of vulva.
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PMID:A clinical and investigational study of donovanosis. 1764 66

Two hundred patients comprising of 144 males and 56 females ranging in age from 10 years to 68 years were studied. The incidence of HIV positive cases in STD patients was 13.5%. Maximum incidence of STD cases were seen in the age group between 21-25 years (27%). Maximum incidence of HIV seropositivity was seen in 19 and 20 years age group (33.8%). In HIV positive cases, there was a male predominance (62.9%). Most of the patients were from low socio-economic status, CSW were the common source and GUD was the most common STD association.
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PMID:Incidence of HIV seropositivity in STD cases. 2092 61