Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:2.7.10.2 (focal adhesion kinase)
 44,029 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

After previous assessment of the dioptric potency (by means of a SRK formula) the authors implanted the appropriate intraocular lenses. After 4-18 months following implantation the calculated refraction calculated before the intervention was compared with the postoperative reality. In 85% the difference was not greater than +/- 1.5 Dsf. The calculation of aniseiconia was made only in case of preoperative ametropia greater than +/- 2 Dsf.
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PMID:[Comparison of the predicted and actual refraction of the eye after intraocular lens implantation]. 233 90

The purpose of this study is to appreciate post-operative ametropia in pseudophakic patients (EEC and posterior chamber IOL). Two groups were implanted either with a standard 21 D IOL (group 1) or after calculation of implant power according to the SRK formula (group 2). Results show residual refractive errors over 2 D in 7% of case in group 2 and 22.3% of case in group 1.
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PMID:[Validity of prediction after standard implant and the implant calculated according to the SRK formula]. 276 Apr 7

The postoperative refraction prediction was evaluated in 99 patients with a 19.0-diopter standard power anterior chamber lens using a theoretical, computer-assisted method based on Gaussian optics and an empirical intraocular lens calculation method based on the SRK formula. Both the theoretical and the empirical predictions accorded with the observed values in the near emmetropia region. In the prediction of ametropia, the SRK method showed a tendency to predict refractions that were lower than the actual values in hyperopic eyes and higher than the actual values in myopic eyes. The bias of the SRK method may be due to the use of an erroneous refraction factor that converts the ametropia to the deviation in implant power from the emmetropia power. By introducing an individual refraction factor, the accuracy of the SRK method approached that of the theoretical method.
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PMID:Theoretical, computer-assisted prediction versus SRK prediction of postoperative refraction after intraocular lens implantation. 357 70

The postoperative refraction of the eye after intraocular lens (IOL) implantation is an important aspect of the quality of aphakia correction. The postoperative refraction cannot be guessed with consistent accuracy as the refractive power of an eye is multifactorial. Calculation of IOL power is based upon measurements of corneal curvature and axial length and an estimation of postoperative anterior chamber depth. There are a number of formulae available for the calculation of IOL power. The optical formulae, of which those of R. D. Binkhorst are the most popular, give results which are very similar and which all differ from the mathematical regression SRK formula by the indication of a stronger IOL power for short eyes. A statistical analysis of postoperative results confirms that the R. D. Binkhorst formula gives the author an over-powered IOL for short eyes when calculated for emmetropia but not when calculated for planned ametropia. Results with the R. D. Binkhorst formula will be improved by the modification of the anterior chamber depth according to the axial length. Both formulae give satisfactory results for the range of axial lengths commonly encountered in clinical practice. Whichever formula is used, it is important for each surgeon to analyse postoperative results and to modify the selection of IOL power according to this feedback to correct for consistent errors of instrumentation or technique.
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PMID:Intraocular lens power calculation--the selection of formula. 386 11

In this retrospective study we compared the preoperative target ametropia, calculated with the SRK-T formula, with the postoperative refraction after extracapsular extraction by phacoemulsification and implantation of different posterior chamber lenses. The results show, for all 3 types of lenses, a postoperative refraction stability after the first month. According to our criteria, after 6 month, we have respectively for the non foldable PMMA lens, the PMMA-copolymere foldable and the acrylic foldable lens: 78%, 72% and 78% of good results; 13%, 28% and 9% of mild results and 9%, 0% and 13% of bad results. According to our criteria, the acrylic foldable lens has a tendency to move slightly backwards and the foldable PMMA-copolymere lens to move slightly frontwards. The non foldable lens gives pretty good results, however it is difficult to compare this lens with the 2 other lenses because of the large size of the incision.
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PMID:[Comparison of preoperative target ametropia and postoperative refraction for three types of lenses and intra-ocular differences (one pliable acrylic, one pliable PMMA-copolymer and one non-pliable PMMA) ]. 1148 62