Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:2.7.10.2 (focal adhesion kinase)
 44,029 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Microwave digestion and isotope dilution inductively coupled plasma mass spectrometry (ID-ICP-SFMS) has been applied to the determination of Pb in rice flour. In order to achieve highly precise determination of low concentrations of Pb, the digestion blank for Pb was reduced to 0.21 ng g(-1) after optimization of the digestion conditions, in which 20 mL analysis solution was obtained after digestion of 0.5 g rice flour. The observed value of Pb in a non-fat milk powder certified reference material (CRM), NIST SRM 1549, was 16.8 +/- 0.8 ng g(-1) (mean +/- expanded uncertainty, k = 2; n = 5), which agreed with the certified value of 19 +/- 3 ng g(-1) and indicated the effectiveness of the method. Analytical results for Pb in three brown rice flour CRMs, NIST SRM 1568a, NIES CRM 10-a, and NIES CRM 10-b, were 7.32 +/- 0.24 ng g(-1) (n = 5), 1010 +/- 10 ng g(-1) (n = 5), and 1250 +/- 20 ng g(-1) (n = 5), respectively. The concentration of Pb in a candidate white rice flour reference material (RM) sample prepared by the National Metrology Institute of Japan (NMIJ) was observed to be 4.36 +/- 0.28 ng g(-1) (n = 10 bottles).
 ...
PMID:Development of a highly precise ID-ICP-SFMS method for analysis of low concentrations of lead in rice flour reference materials. 1850 30

This paper proposes an in vitro hemodiafiltration (HDF) model in which the patient is represented by a 2 L bag of fresh heparinized bovine blood circulated by a 4008H monitor through a 0.6 m2 hemodialyzer to investigate kinetics of bicarbonate (HCO,) during online post-dilution HDF. Five tests were carried out, with three ultrafiltration rates, zero (HD test), 30 and 50 ml/min. Blood gases, pH, HCO3, hematocrit and electrolytes were measured with an ABL 77 (Radiometer) blood gas analyzer, and HCO3- was simultaneously measured with a biochemistry analyzer. The variation over time of plasma HCO3- concentrations was also calculated using mass conservation and the model of Legallais et al (JMS 168, 2000, 3-15). Agreement between theoretical and measured concentrations was good during the first 25 minutes of each test, corresponding to the time necessary to dialyze the blood. In hemodialysis (HD), there was an HCO3- mass transfer into blood through the membrane due to diffusion which vanished after 40 minutes, while in HDF tests, blood lost HCO3 due to ultrafiltration after 10 minutes. With reinjection, the net HCO3- mass flow rate to the "patient" decayed, from 1.8 mmol/min at t = 0 to zero at the end of the test (t = 60 min), and was higher in HD than in HDF "Patient" dialysance, taking into account reinjection, was positive in all tests, and decayed from about 110 ml/ min to 40 m/min at the end of dialysis. These data confirmed that online HDF automatically corrects acidosis without creating alkalosis when HCO3- dialysate concentration is around 30 mmol/L.
 ...
PMID:In vitro tests and modelization of bicarbonate kinetics and mass transfers during online hemodiafiltration. 1984 92