Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:2.7.10.2 (focal adhesion kinase)
 44,029 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Fifty consecutive patients who had cataract extraction and intraocular lens implantation with a can-opener anterior capsulotomy were compared to 50 patients who had a continuous tear capsulotomy and confirmed capsular bag lens placement. The actual versus the predicted postoperative refraction was calculated with both the SRK II and the Holladay lens power formulas. With both formulas, the capsulorhexis patients required a spectacle correction 0.43 (or 0.44) diopter greater than the can-opener patients when the same A-constant or surgeon factor was used. The recalculated A-constant was 118.23 for the can-opener patients and 118.76 for the capsulorhexis patients; the manufacturer's recommended A-constant was 118.3. The results were statistically significant.
J Cataract Refract Surg 1992 Mar
PMID:Refractive effect of capsular bag lens placement with the capsulorhexis technique. 156 47

Five methods for predicting pseudophakic anterior chamber depth (ACD) by five previously described intraocular lens power calculation formulas (Binkhorst II, Lepper and Trier, Holladay et al., Sanders-Retzlaff-Kraff (SRK/T), Olsen et al.) were evaluated in a series of 640 patients with a posterior chamber lens implant. Significant differences in formula performance were found in unusually short and long eyes. High errors were found in long eyes with the Lepper and Trier formula, the Holladay formula, and the SRK/T method. The highest accuracy was found with the Binkhorst formula and our previously described linear regression formula which expresses the pseudophakic ACD as a function of the average pseudophakic ACD for a given lens style, the preoperative ACD, and the axial length. The use of the preoperative ACD in combination with the axial length for the prediction of the pseudophakic ACD can therefore be expected to improve the accuracy of IOL power calculation.
J Cataract Refract Surg 1992 May
PMID:Prediction of pseudophakic anterior chamber depth with the newer IOL calculation formulas. 159 34

A retrospective study of 183 eyes that had undergone extracapsular cataract extraction and posterior chamber intraocular lens (IOL) implantation was undertaken to compare the accuracy of eight IOL power calculation formulas (modified Binkhorst, Colenbrander, Gullstrand, Fyodorov-Galin-Linksz, Gill, Axt, Donzis-Kastle-Gordon and SRK regression). We found that the regression formulas were more accurate than the theoretical formulas, giving enough approximation to the ideal IOL as to assure its clinical use. We prefer the SRK formula because it is easier and it has a constant A that can be adapted in a personalized way to each surgical team.
 ...
PMID:A comparative study of eight intraocular lens calculation formulas. 177 3

Axial length and corneal curvature are entered into formulae to calculate intraocular lens power for cataract surgery and the absolute measurement of fundus structures such as neuroretinal rim area in glaucoma. The reproducibility (coefficient of variation, CV) of biometry and keratometry was investigated by taking five measurements of thirty phakic eyes. Although both techniques were found to be highly reproducible (CV less than 1%), keratometry was the more so. However, a clinically significant difference was noted between the first and the mean of five readings for both biometry (0.15 +/- 0.05 mm) and keratometry (0.05 +/- 0.03). Taken together, these errors would result in a postoperative refractive error of 0.65D using the SRK formula. Measurement errors were just as likely to occur with short or long eyes. Similar results were found when the analysis was performed on three measurements of both axial length and corneal curvatures. We recommend taking the average of three biometry and keratometry readings to improve the reliability of the techniques, and to increase the accuracy of calculating intraocular lens power and fundus structure dimensions.
 ...
PMID:The reproducibility of biometry and keratometry measurements. 180 Jan 71

The accuracy of two newer generation theoretical intraocular lens (IOL) power calculation formulas and of the empirical SRK I and II formulas was evaluated in a series of 500 IOL implantations including a series of unusually long and short eyes. The prediction error of the theoretical formulas was found to be largely unaffected by the variation in axial length and corneal power, while the prediction of the SRK I formula was less accurate in the short and long eyes. The prediction of the SRK II formula was more accurate than the SRK I in that no systematic offset error with axial length could be demonstrated. However, because of a relatively larger scatter in the long eyes and a significant bias with the corneal power, the absolute error of the SRK II formula was higher than that of the theoretical formulas in the long eyes. The higher accuracy of the newer generation theoretical formulas was attributed to their improved prediction of the pseudophakic anterior chamber depth.
J Cataract Refract Surg 1991 Mar
PMID:Accuracy of the newer generation intraocular lens power calculation formulas in long and short eyes. 204 Sep 76

A series of 90 eyes of 88 myopic patients who underwent extracapsular cataract surgery with intraocular lens implants (IOLs) between 1984 and 1989 were analysed in a retrospective study. The axial length as obtained by ultrasonic A scan and keratometry readings were applied to the SRK1 and modified SRK (SRK2) formulae and the result compared with the actual post-operative state achieved.
 ...
PMID:An analysis of the accuracy of prediction of intraocular implant power in the myopic patient. 206 Jun 73

The preoperative and postoperative influence of different parameters on the predictability of formulas used for intraocular lens (IOL) power calculation (axial length, corneal dioptric power, IOL malposition, postoperative astigmatism) has been shown by various authors. In this study, we evaluated the preoperative astigmatic influence on the prediction of postoperative refraction in eyes operated on for cataract with IOL implantation. Three hundred and fifty-nine eyes were evaluated after cataract surgery and IOL implantation. We calculated predictive errors of both the Binkhorst and SRK formulas for each eye. Based on the outcome of the predictive errors we divided the eyes into six groups: three of high and three of low predictability. Preoperative astigmatism in these groups was statistically compared (using the Student's t-test). The preoperative astigmatism was always higher in the group with low predictability than in the group with high predictability (P less than .05).
J Cataract Refract Surg 1990 Sep
PMID:Preoperative astigmatic influence on the predictability of intraocular lens power calculation. 223 75

The anterior chamber depth was measured in 15 eyes with sulcus placed (Group 1) and 12 eyes with bag placed (Group 2) IOGEL PC-12 lenses, and in 11 eyes with bag placed IOGEL 1103 lenses (Group 3). The mean anterior chamber depth was 3.29 mm in Group 1, 4.17 mm in Group 2, and 4.16 mm in Group 3. The difference between the mean anterior chamber depth with sulcus and bag placed IOGEL PC-12 lenses is statistically significant (P less than .0005). One effect of the different anterior chamber depths was that the anterior surface of a sulcus placed IOGEL lens frequently touched the pupillary border, whereas this rarely occurred when it was placed in the capsular bag. Another effect of differing anterior chamber depths was a different A-constant for the SRK-formula for sulcus or bag placement. In this study it was about 1 diopter greater with bag fixation than with sulcus fixation. It is recommended that each surgeon use specific A-constants to enhance the predictability of the postoperative refraction.
J Cataract Refract Surg 1990 Nov
PMID:Anterior chamber depth with sulcus and capsular bag placed IOGEL lenses. 225 10

Analytical predictions of primary implant power using presumptive errors in keratometer and axial length measurements were performed using the modified Binkhorst, modified Colenbrander, Holladay, Hoffer, and SRK II equations. These predictions demonstrate that the contributions to primary implant power error resulting from inaccurate axial length and keratometer measurements are algebraically additive. In eyes with a normal axial length, the resulting implant power determination error can be larger than differences in implant power prediction among these five IOL equations. Calculations using measurement errors of 0.2 mm in axial length and 0.50 diopter (D) in corneal curvature predicted a worst case primary implant power error of +/- 1.17 D. These calculations were performed using an axial length and corneal curvature near the population mean. In contrast, implant equation variability was determined to be +/- 0.19 D by calculating the standard deviation of the five implant power formulas with the measurement errors set to zero. Implant power prediction errors were increased when a flat cornea was paired with an axial hyperopic or an axial myopic eye. These combinations maximize the implant power error resulting from both implant formula variation and inaccurate measurements. Primary implant power error prediction tables are presented for emmetropic, axial hyperopic, and axial myopic eyes, as a function of presumed errors in axial length and corneal curvature. These error predictions clearly show that inaccuracy in axial length measurements and keratometer readings can be first order determinants of postoperative spherical refractive error.
J Cataract Refract Surg 1990 Jan
PMID:Effect of keratometer and axial length measurement errors on primary implant power calculations. 229 77

We compared the accuracy of the Holladay and SRK II intraocular lens power calculation formulas with that of two commonly used formulas, the Binkhorst and SRK. We found no significant difference between the accuracy of the four formulas in cases of posterior chamber lens implantation. For anterior chamber lenses, the SRK II formula was significantly less accurate than the other three formulas in eyes with long axial length.
J Cataract Refract Surg 1990 Jan
PMID:Clinical evaluation of the Holladay and SRK II formulas. 229 78


1 2 3 4 5 6 7 8 9 Next >>