Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:2.7.10.2 (focal adhesion kinase)
 44,029 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

A principally new programme is described which overcomes the disadvantages of the usual calculation methods. It is based on the application of each surface of the optical system. The point for the anterior chamber lens is chosen in dependence on the anterior chamber depth; for the posterior chamber lens on the posterior surface of the eye lens. The programme is able to calculate 12 different cases. In each case calculations are made for intraocular lens power, aniseikonia and anisometropia. The calculations are made for possible emmetropia as well as for intended myopia or hypermetropia corresponding to the other eye. The programme can also be used to estimate the effect of mistakes made by measuring the single parameters, for instance: refraction, corneal curvature, eye length, anterior chamber depth. Compared to the SRK II-equation the results of the new programme are much more precise.
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PMID:[A new program for calculating intraocular lenses]. 145 63

Intraocular lens power calculation is increasing in use in the United Kingdom. Primarily to avoid anisometropia, intraocular lens power calculation may also be used to provide the patient with three rather than two working distances, but to achieve this greater accuracy of IOL power calculation is required. Using the SRK regression formula, three groups of patients have been studied. The effect of inaccurate use of the formula of choice is shown and the need to modify the 'A' constant to account for variation both in technique and biometry equipment emphasised. The variation in results due to inaccurate biometry are statistically assessed. Accuracy of IOL power calculation requires consistency but not absolute accuracy in biometry. No ocular factors were found to affect the accuracy of IOL power calculation.
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PMID:Factors affecting intraocular lens power calculation. 347 92

With the increasing number of keratorefractive surgical procedures, an increasing number of cataract surgeries in eyes after keratorefractive surgery is anticipated within a few decades. Although cataract extraction seems to be feasible without major technical obstacles, intraocular lens (IOL) power calculation turned out to be problematic. Insertion of the measured average K-readings (= "central corneal power" = keratometric diopters) after myopic radial keratotomy (RK), photorefractive keratectomy (PRK), or laser in situ keratomileusis (LASIK) into standard IOL power-predictive formulas commonly results in substantial undercorrection and postoperative hyperopic refraction or anisometropia. In this article, the major reasons for IOL power miscalculations (which are different for RK versus RRK/LASIK) are discussed based on model calculations and based on case series of cataract surgeries, methods for improved assessment of keratometric diopters as the major underlying problem are exemplary illustrated, and finally a clinical step-by-step approach to minimize IOL power miscalculations status after corneal refractive surgery is suggested. The "clinical history method" (i.e., subtraction of the spherical equivalent [SEQ] change after refractive surgery from the original K-reading) should be applied whenever refraction and K-reading before the keratorefractive procedure are available to cataract surgeons. In addition, more than one modern third-generation formula (e.g., Haigis, Hoffer Q, Holladay 2, or SRK/T) but not a regression formula (e.g., SRK I or SRK II) should be applied and the highest resulting IOL power should be used for the implant.
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PMID:Intraocular lens calculations status after corneal refractive surgery. 1072 26