Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:2.7.10.1 (ERK)
 95,504 document(s) hit in 31,850,051 MEDLINE articles (0.08 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
ERK 0.275
EGFR 0.145
HER2 0.105
PCL 0.053
MET 0.044
KIT 0.043
RET 0.034
MEK 0.028
ALK 0.028
FLT3 0.026
anaplastic lymphoma kinase 0.021
FGFR1 0.020
VEGFR2 0.020
KDR 0.018
MAPK 0.018
ERBB2 0.018
PDGFR 0.015
tyrosine kinase 0.015
JNK 0.013
NET 0.013
FGFR2 0.013
PDGFRA 0.012
FGFR3 0.012
IGF1R 0.011
p38 0.011
AKT 0.010
ERK1 0.010
receptor tyrosine kinase 0.010
epidermal growth factor receptor 0.009
PI3K 0.008
BRAF 0.008
HER3 0.008
HEP 0.007
neu 0.007
ROS1 0.007
KRAS 0.007
NEP 0.006
AXL 0.006
IRR 0.005
VEGFR-1 0.005
RAF 0.005
c-fms 0.004
MEK1 0.004
FGFR4 0.004
EML4 0.004
PDGFRB 0.004
PIK3CA 0.004
ERBB 0.004
ACH 0.004
EPH 0.004
NTRK1 0.004
TRK 0.004
ERBB3 0.004
PTK 0.003
HER4 0.003
TIF 0.003
CSF1R 0.003
RON 0.003
RET proto-oncogene 0.003
NTRK3 0.003
NRAS 0.003
VEGF 0.003
ERBB4 0.003
MER 0.003
NPM1 0.003
EGF 0.003
tyrosine kinase 3 0.003
ERK2 0.003
INSR 0.002
FLT1 0.002
mTOR 0.002
receptor protein tyrosine kinase 0.002
MAP kinase 0.002
tyrosine kinase receptor 0.002
vascular endothelial growth factor 0.002
DDR1 0.002
HTK 0.002
platelet-derived growth factor receptor 0.002
NTRK2 0.002
FLG 0.002
more...
Disease
PCL 0.052
HEP 0.007
tumor 0.007
breast cancer 0.007
cancer 0.006
non-small cell lung cancer 0.004
anaplastic large cell lymphoma 0.003
stromal tumors 0.002
gastrointestinal stromal tumor 0.002
achondroplasia 0.002
lung cancer 0.002
acute myeloid leukemia 0.002
tumor growth 0.002
medullary thyroid carcinoma 0.002
tumorigenesis 0.002
metastatic breast cancer 0.001
MEN 2 0.001
adenocarcinoma 0.001
MEN 2B 0.001
tumor progression 0.001
multiple endocrine neoplasia 0.001
HGF 0.001
carcinoma 0.001
metastases 0.001
glioblastoma 0.001
colorectal cancer 0.001
mastocytosis 0.001
MCF 0.001
melanoma 0.001
psychopathy 0.001
papillary thyroid cancer 0.000
gastric cancer 0.000
tumor angiogenesis 0.000
carcinogenesis 0.000
leukemia 0.000
ductal carcinoma 0.000
glioma 0.000
brain metastases 0.000
lung carcinoma 0.000
squamous cell carcinoma 0.000
hepatocellular carcinoma 0.000
ABL 0.000
chronic eosinophilic leukemia 0.000
mast cell leukemia 0.000
MTC 0.000
thyroid cancer 0.000
ovarian cancer 0.000
primary tumor 0.000
JWS 0.000
Luminal 0.000
pancreatic cancer 0.000
aggressiveness 0.000
EMT 0.000
Hippel 0.000
colon cancer 0.000
neuroblastoma 0.000
Pfeiffer syndrome 0.000
Glioblastoma 0.000
craniosynostosis 0.000
ductal carcinoma in situ 0.000
Apert syndrome 0.000
adult AML 0.000
Crouzon syndrome 0.000
prostate cancer 0.000
pediatric AML 0.000
lymphoma 0.000
leukemogenesis 0.000
glioblastoma multiforme 0.000
chronic myeloid leukemia 0.000
Leukemia 0.000
sarcoma 0.000
renal cell carcinoma 0.000
IMT 0.000
Systemic mastocytosis 0.000
myeloproliferative disorders 0.000
pheochromocytoma 0.000
small cell lung cancer 0.000
Mastocytosis 0.000
mammary tumor 0.000
bladder cancer 0.000
more...
Symptom
diarrhea 0.000
pain 0.000
nausea 0.000
fatigue 0.000
Increased skin sensitivity 0.000
Oral pruritus 0.000
starvation 0.000
anosmia 0.000
retracted nipple 0.000
functional recovery 0.000
vomiting 0.000
decreased appetite 0.000
Scratch 0.000
splenomegaly 0.000
Braxton Hicks contractions 0.000
nipple discharge 0.000
nipple discharge 0.000
dry skin 0.000
abdominal pain 0.000
skin damage 0.000
seizures 0.000
hyperoxia 0.000
ACHE 0.000
HSA 0.000
cough 0.000
asthenia 0.000
anorexia 0.000
headache 0.000
irregular bleeding 0.000
constipation 0.000
collapse 0.000
bone pain 0.000
flushing 0.000
dyspnea 0.000
High weight 0.000
overweight 0.000
exhaustion 0.000
Respiratory abnormalities 0.000
memory loss 0.000
peau d'orange 0.000
weakness 0.000
unable to sleep 0.000
Neuropathic pain 0.000
difficulty with urination 0.000
peri-menopausal 0.000
Erythema annulare centrifugum 0.000
Sore 0.000
orofacial pain 0.000
chills 0.000
hepatosplenomegaly 0.000
Intermenstrual bleeding 0.000
Inflammatory pain 0.000
hypothermia 0.000
respiratory distress 0.000
fasciculation 0.000
erythema 0.000
breast hyperplasia 0.000
hyperosmia 0.000
epigastric pain 0.000
analgesia 0.000
Spotting 0.000
periorbital edema 0.000
cachexia 0.000
shortness of breath 0.000
muscle cramps 0.000
thinning 0.000
night sweats 0.000
BHS 0.000
dizziness 0.000
stomach cramps 0.000
discomfort 0.000
discomfort 0.000
arthralgia 0.000
female puberty 0.000
Beau's lines 0.000
anesthesia 0.000
back pain 0.000
hepatomegaly 0.000
Severe diarrhea 0.000
DNA marker 0.000
more...
Drug
Herceptin 0.005
ENT 0.002
Gefitinib 0.001
Imatinib 0.001
Cetuximab 0.001
Erlotinib 0.001
Gleevec 0.001
MAP 0.001
PTC 0.000
Sorafenib 0.000
Pertuzumab 0.000
Midostaurin 0.000
ROS 0.000
DM1 0.000
Vandetanib 0.000
Tarceva 0.000
MTC 0.000
NVP 0.000
Tykerb 0.000
Dasatinib 0.000
ETS 0.000
Bevacizumab 0.000
Panitumumab 0.000
KGF 0.000
TEL 0.000
GEO 0.000
Sunitinib malate 0.000
Nexavar 0.000
uPA 0.000
CSF 0.000
Fulvestrant 0.000
Mubritinib 0.000
Axitinib 0.000
Lestaurtinib 0.000
IL-2 0.000
CDX 0.000
ICI 0.000
Docetaxel 0.000
anti-CD33 0.000
Everolimus 0.000
Pelitinib 0.000
Taxol 0.000
CDX 0.000
lysine 0.000
Pemetrexed 0.000
Tandutinib 0.000
Paraffin 0.000
CTC 0.000
IFN-gamma 0.000
Motesanib 0.000
TAK 0.000
Ixabepilone 0.000
Tipifarnib 0.000
Vatalanib 0.000
Angiotensin II 0.000
G-CSF 0.000
Diapid 0.000
ERLOTINIB 0.000
Cetyl-Trimethyl-Ammonium 0.000
p75 0.000
Activin 0.000
MDS 0.000
Condurango 0.000
MRC 0.000
PDGF B-chain 0.000
Epigallocatechin 0.000
CAM 0.000
Arsenic trioxide 0.000
Dexamethasone acetate 0.000
Nicergolin 0.000
Timefurone 0.000
Poliglecaprone 25 0.000
Tiqueside 0.000
Dermatol 0.000
ROC 0.000
EE2 0.000
CPT-11 0.000
Taxotere 0.000
Simvastatin 0.000
EML 0.000
more...
Enzyme
ERK 1.000
mitogen-activated protein kinase 0.030
MEK 0.027
focal adhesion kinase 0.002
protein kinase 0.001
STK 0.001
MAP 0.001
protein kinase C 0.001
phosphatidylinositol 3-kinase 0.001
CD10 0.001
caspase-3 0.000
succinyl-CoA synthetase 0.000
PARP 0.000
MEKK1 0.000
phosphoinositide 3-kinase 0.000
luciferase 0.000
DAT 0.000
STK11 0.000
AMPK 0.000
cdc2 0.000
GSK 0.000
AMP-activated protein kinase 0.000
IKK 0.000
caspase-9 0.000
AMPK 0.000
PDK1 0.000
NADPH oxidase 0.000
caspase-8 0.000
MMP 0.000
phospholipase C 0.000
proteasome 0.000
calcineurin 0.000
NADPH oxidase 0.000
urokinase-type plasminogen activator 0.000
CaMKII 0.000
APC 0.000
CEP 0.000
matriptase 0.000
alkaline phosphatase 0.000
tryptase 0.000
collagenase 0.000
GRK5 0.000
CD13 0.000
CEP 0.000
DCF 0.000
protein phosphatase 2A 0.000
reverse transcriptase 0.000
ACS 0.000
matriptase 0.000
NOS 0.000
GRK2 0.000
sphingosine kinase 0.000
cathepsin K 0.000
succinate dehydrogenase 0.000
farnesyltransferase 0.000
superoxide dismutase 0.000
RNA polymerase 0.000
catalase 0.000
P-glycoprotein 0.000
glutathione S-transferase 0.000
TACE 0.000
inositol 3-kinase 0.000
topoisomerase 0.000
topoisomerase 0.000
phosphatidylinositol-4,5-bisphosphate 3-kinase 0.000
farnesyltransferase 0.000
MIP 0.000
granzyme B 0.000
ALDH 0.000
MMP-3 0.000
HK2 0.000
L-rhamnonate dehydratase 0.000
L-rhamnonate dehydratase 0.000
PKG 0.000
thymidine kinase 0.000
p80 0.000
NO synthase 0.000
caspase-7 0.000
caspase-7 0.000
hepsin 0.000
more...
Compound
MEK 0.027
HEP 0.007
methionine 0.004
tyrosine 0.003
TIF 0.002
MAP 0.001
DNA 0.001
MDA 0.001
MTT 0.000
TNF 0.000
PEG 0.000
PEG 0.000
ABL 0.000
BCR 0.000
DAT 0.000
NEU 0.000
Dec 0.000
serine 0.000
threonine 0.000
oxygen 0.000
cAMP 0.000
MTC 0.000
Cbl 0.000
Tyrosine 0.000
quinazoline 0.000
quinazoline 0.000
Luminal 0.000
PLA 0.000
calcium 0.000
ATP 0.000
CLTC 0.000
Clin 0.000
PMA 0.000
DFS 0.000
Vimentin 0.000
ATF 0.000
THP 0.000
THP 0.000
retinoic acid 0.000
TNM 0.000
TEL 0.000
cysteine 0.000
PMA 0.000
nitric oxide 0.000
acetate 0.000
glucose 0.000
N-acetylcysteine 0.000
ENU 0.000
2-Keto-L-gulonic acid 0.000
SEE 0.000
phosphate 0.000
Insulin 0.000
PGE 0.000
Curcumin 0.000
Wortmannin 0.000
LY 294002 0.000
Estrogen 0.000
Ang II 0.000
Estrogen 0.000
water 0.000
GTP 0.000
Paclitaxel 0.000
SCC 0.000
arginine 0.000
ADR 0.000
lysine 0.000
MTS 0.000
ACS 0.000
COS 0.000
ACS 0.000
ALP 0.000
DDP 0.000
Rapamycin 0.000
CAP 0.000
Phe 0.000
IDC 0.000
CAM 0.000
DPG 0.000
Luteolin 0.000
Tamoxifen 0.000
more...