Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:2.7.10.1 (ERK)
 95,504 document(s) hit in 31,850,051 MEDLINE articles (0.08 seconds) .

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Human Gene/Protein
HER3 8.4
PLSCR5 8.4
FAM160B2 8.4
PDGFRB 8.4
PP14571 8.4
TMEM167A 8.4
RET 8.4
BAIAP1 8.4
TMEM108 8.4
TKT1 8.4
Ubiquitin-conjugating enzyme E2 J2 8.4
OR4C16 8.4
C17orf77 8.4
F-box and leucine-rich repeat protein 6 8.4
receptor protein tyrosine kinase 8.4
CRISPLD1 8.4
ELK1, member of ETS oncogene family 8.4
C8orf55 8.4
Signal protein 8.4
HIST1H2AI 8.4
RYK 8.4
C14orf181 8.4
ERBB4 protein 8.4
HNK1ST 8.4
ALK 8.4
CAPPA1 8.4
anaplastic lymphoma kinase 8.4
protein tyrosine phosphatase, receptor type, f polypeptide 8.4
UEVLD 8.4
TYRO3 8.4
GCST 8.4
LRRC4B 8.4
MET 8.4
FGFR2 8.4
spectrin repeat containing, nuclear envelope 2 8.4
ASB-9 8.4
C9orf43 8.4
C6orf182 8.4
chromosome 7 open reading frame 41 8.4
DAZ-associated protein 1 8.4
EHK1 8.4
CED12 8.4
SRF accessory protein 1 8.4
ERBB3 8.4
NACC2 8.4
receptor protein-tyrosine kinase 8.4
TYRO3 protein 8.4
TRK 8.4
TYRO4 8.4
RPS6KA6 protein 8.4
transforming growth factor, alpha 8.4
ROR1 8.4
MS4A6 8.4
FLJ35024 8.4
RYK protein 8.4
KDEL (Lys-Asp-Glu-Leu) containing 2 8.4
ZMYM6 8.4
OR8S1 8.4
non-protein coding RNA 52 8.4
MER receptor tyrosine kinase 8.4
jumonji C domain containing histone demethylase 1 homolog D 8.4
AP1G2 8.4
C16orf63 8.4
MRIP-1 8.4
NCKIPSD 8.4
Src homology 2 domain containing F 8.4
NEP 8.4
MS4A4 8.4
FAM180A 8.4
ZNF526 8.4
ORC3L 8.4
CSF1R 8.4
vascular endothelial growth factor/vascular permeability factor receptor 8.4
PTPN5 protein 8.4
left-right determination, factor B 8.4
HGFR 8.4
Ras-like protein family member 11B 8.4
ELE1-RET 8.4
FGFR4 8.4
guanine nucleotide-releasing factor 2 8.4
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Disease
Bowen's disease, pagetoid 8.4
Inflammatory fibroid polyps of stomach 8.4
FIM1 8.4
ALKoma 8.4
Mesenchymal Neoplasm 8.4
Reactive mastocytosis 8.4
MLVI2 8.4
T-cell lymphoma refractory 8.4
Bent bone dysplasia 8.4
metastatic adult soft tissue sarcoma 8.4
genetics of medullary thyroid cancer 8.4
AML with recurrent genetic abnormality 8.4
Haemangioblastomatosis 8.4
Spindle Cell Tumor 8.4
childhood large cell lymphoma 8.4
Idiopathic eosinophilia 8.4
HEP 8.4
PCL 8.4
JWS 8.0
VMCM 7.9
KAL2 7.9
SM-AHNMD 7.6
Glycogen-rich carcinoma 7.4
Cystic hypersecretory carcinoma 7.4
Pilocytic Astrocytoma 7.4
adenosquamous cell lung cancer 7.4
low-grade salivary gland carcinoma 7.4
Say-Meyer syndrome 7.4
High altitude polycythemia 7.4
adult brainstem glioma 7.4
MEN 2B 7.3
Medullary Thyroid Carcinoma 7.2
chronic eosinophilic leukemia 7.2
MEN 2 7.1
mast cell leukemia 7.1
Secretory Carcinoma 7.1
achondroplasia 7.0
anaplastic large cell lymphoma 7.0
HSAN IV 6.9
Pulmonary granulomatosis 6.8
LACH 6.8
Intracystic carcinoma 6.8
Septicemic pasteurellosis 6.8
oligocythemia 6.8
TLPD 6.8
Nutritional muscular dystrophy 6.8
Xp21-linked muscular dystrophy 6.8
VMOS 6.8
DFNB39 6.8
Non-Langerhans cell histiocytosis 6.8
GINGF3 6.8
DFNB26 6.8
Gastrointestinal motility disorder 6.8
adult oligodendroglioma 6.8
RP33 6.8
Familial mastocytosis 6.8
relapsed adult AML 6.8
Intestinal Dysplasia 6.8
Childhood conduct disorder 6.8
localized resectable neuroblastoma 6.8
Candida leukoplakia 6.8
Pfeiffer syndrome 6.7
IGCNU 6.6
Gastroesophageal cancer 6.6
Anaplastic Lymphoma 6.6
CACD 6.6
CMML-2 6.6
childhood ependymoma 6.6
ring chromosome 15 syndrome 6.5
Gestosis 6.5
gastrointestinal stromal tumor 6.5
HER-2 positive breast cancer 6.5
stromal tumors 6.4
Obstructive atelectasis 6.4
APSM 6.4
monosomy 15q 6.4
HPC3 6.4
Mesenteric fibrosis 6.4
Scirrhous gastric carcinoma 6.4
CACD 6.4
more...
Symptom
Increased skin sensitivity 8.4
Oral pruritus 8.4
retracted nipple 6.8
Braxton Hicks contractions 5.6
High weight 4.1
Respiratory abnormalities 4.0
unable to sleep 3.9
difficulty with urination 3.6
Sore 3.6
Erythema annulare centrifugum 3.6
Scratch 3.6
peau d'orange 3.5
Intermenstrual bleeding 3.4
ACHE 3.3
breast hyperplasia 3.3
hyperosmia 3.3
nipple discharge 3.2
Inflammatory pain 3.2
nipple discharge 3.1
anosmia 3.0
Spotting 2.9
peri-menopausal 2.9
decreased appetite 2.8
stomach cramps 2.8
irregular bleeding 2.8
Beau's lines 2.7
BHS 2.6
Severe diarrhea 2.6
dry skin 2.6
female puberty 2.5
GI irritation 2.4
periorbital edema 2.4
eye discharge 2.3
Skin symptoms 2.3
skin damage 2.2
No toxic effect 2.0
Lhermitte's sign 2.0
Motor dysfunction 2.0
prominent nose 2.0
delayed language development 2.0
frequent urination 2.0
throat irritation 1.9
onychomadesis 1.9
body pain 1.9
skin irritant 1.8
orofacial pain 1.8
generalized pain 1.8
Buckling 1.7
Burning 1.7
Neuropathic pain 1.7
Cushingoid 1.6
asthenia 1.6
Visual symptoms 1.6
Cushingoid 1.6
Visual disturbances 1.6
muscle cramps 1.6
HSA 1.5
Visceral pain 1.5
fasciculation 1.5
anal pain 1.5
nausea 1.5
Joint hypermobility 1.4
bigeminal 1.4
bone pain 1.4
functional recovery 1.3
DNA marker 1.3
photopsia 1.3
night sweats 1.3
splenomegaly 1.3
hyperoxia 1.3
starvation 1.3
diarrhea 1.2
memory loss 1.1
Fluctuation 1.1
startle reaction 1.1
No adverse effect 1.1
lightheadedness 1.0
scaly skin 1.0
hypalgesia 0.9
Flare 0.9
more...
Drug
Diapid 8.4
Pelitinib 8.4
Cetyl-Trimethyl-Ammonium 8.4
ERLOTINIB 8.4
Mubritinib 8.1
Midostaurin 7.9
Pertuzumab 7.4
Condurango 7.4
Herceptin 7.3
Lestaurtinib 7.3
Tykerb 7.2
Tandutinib 7.2
Vandetanib 6.9
Poliglecaprone 25 6.8
Tiqueside 6.8
Nicergolin 6.8
Timefurone 6.8
Gefitinib 6.6
Erlotinib 6.6
Tarceva 6.4
Cetuximab 6.4
Antirabies serum 6.4
D-Aspartic Acid 6.4
Efipladib 6.4
Panitumumab 6.3
Motesanib 6.3
Nexavar 6.2
Mudanpi 6.1
Ecadotril 6.1
Rimexolone 6.1
Imatinib 6.0
Sunitinib malate 6.0
Gleevec 6.0
Dexamethasone acetate 5.9
MTC 5.8
Xaliproden 5.8
Fudosteine 5.8
Vatalanib 5.7
Sorafenib 5.7
Axitinib 5.7
ENT 5.6
PTC 5.6
Nalfurafine hydrochloride 5.6
Erben 5.6
Dasatinib 5.5
KGF 5.5
Tipifarnib 5.4
5-Iodouracil 5.4
Oregovomab 5.4
Alexidine 5.4
Ixabepilone 5.3
NVP 5.3
DM1 5.3
Colestid 5.2
Bavituximab 5.2
Oncophage 5.2
CDX 5.1
Hymenialdisine 5.1
Indacrinone 5.1
Irsogladine maleate 5.1
Seratrodast 5.1
Fulvestrant 5.0
Mevastatin 5.0
TEL 4.9
Piclamilast 4.9
Piclamilast 4.9
anti-CD33 4.8
Ilomastat 4.7
Bevacizumab 4.7
Emcyt 4.7
CDX 4.7
Bosutinib 4.6
Amlexanox 4.5
PDGF B-chain 4.5
Dexibuprofen 4.5
Arundic acid 4.5
ETS 4.4
Pemetrexed 4.4
C.M.C. 4.4
Candoxatril 4.4
more...
Enzyme
ERK 8.4
STK 8.2
L-rhamnonate dehydratase 7.4
L-rhamnonate dehydratase 7.4
MEK 7.0
zingipain 6.8
L-rhamnose 1-dehydrogenase 6.8
succinyl-CoA synthetase 6.7
D-2-hydroxy acid dehydrogenase 6.4
dipeptidyl-dipeptidase 6.4
STK11 6.1
mitogen-activated protein kinase 5.9
sorbose dehydrogenase 5.7
complement subcomponent C1r 5.6
prenylated protein methyltransferase 5.4
DAT 5.4
MEKK1 5.3
STK13 5.2
MAP 5.2
HK3 5.2
DNA 3'-phosphatase 5.2
acylcarnitine hydrolase 5.0
CobS 4.9
phosphatidylinositol-4,5-bisphosphate 3-kinase 4.9
hepsin 4.9
hepsin 4.9
inositol 3-kinase 4.9
gamma-butyrobetaine hydroxylase 4.8
matrix metalloproteinase 10 4.8
matriptase 4.8
matriptase 4.8
phosphatidylinositol 3-kinase 4.7
CD10 4.7
CEP 4.6
focal adhesion kinase 4.5
STK4 4.5
GK2 4.5
phosphoinositide 3-kinase 4.5
meprin B 4.5
STK2 4.4
PDK1 4.4
phenylacetyl-CoA ligase 4.4
phosphatidylinositol 3-phosphate 5-kinase 4.4
sphingosine kinase 4.3
MHCK 4.3
small monomeric GTPase 4.2
GRK2 4.2
XMT 4.1
GRK5 4.1
CEP 4.1
PARP 4.1
HK2 4.1
glutathione oxidase 4.1
trans-N-deoxyribosylase 4.1
IKK 4.1
p80 4.0
AMPK 4.0
TACE 4.0
farnesyltransferase 3.9
chondroitin 4-sulfotransferase 3.9
GSK 3.9
alpha-methylacyl-CoA racemase 3.9
deuterolysin 3.9
CLK1 3.9
CTD kinase 3.8
endothelin-converting enzyme 3.8
ALDH 3.8
NQO2 3.8
MMP 3.8
cdc2 3.8
peptidylarginine deiminase 3.7
rhodopsin kinase 3.7
DCF 3.7
3-hydroxy-3-methylglutaryl-CoA lyase 3.7
scytalone dehydratase 3.7
caspase-7 3.7
protein kinase C 3.6
protein kinase 3.6
CaMKII 3.6
caspase-7 3.6
more...
Compound
TIF 8.4
C15H20O 8.4
C15H20O 8.4
Isobutyl methacrylate 8.4
1-Propylagroclavine tartrate 8.4
Iodinin 8.4
C15H20O 8.4
Ethyl Malonate 8.4
HEP 8.4
C15H20O 8.4
Strebloside 8.4
C15H20O 8.4
1,3,7-Trihydroxyxanthone 8.4
C15H20O 8.4
C15H20O 8.4
C15H20O 8.4
C15H20O 8.4
C25H30N2O5 8.4
Spiclomazine 8.4
4-(3-chloropropyl)morpholine 8.4
C15H20O 8.4
C15H20O 8.4
2-(trifluoromethyl)-10H-phenothiazine 8.4
2-Keto-L-gulonic acid 7.9
2,4,5-trichloropyrimidine 7.8
C7H14N2O3 7.4
C7H14N2O3 7.4
C7H14N2O3 7.4
1,2,3,4,5,6-hexabromocyclohexane 7.4
Neoastilbin 7.4
C7H14N2O3 7.4
C7H14N2O3 7.4
1-phenyl-1-nonen-3-one 7.4
C7H14N2O3 7.4
C13H18N2 7.4
C7H7Cl 7.4
C7H14N2O3 7.4
2-chloronicotinonitrile 7.4
C7H14N2O3 7.4
C15H20O 7.4
C7H14N2O3 7.4
C7H14N2O3 7.4
C7H14N2O3 7.4
C7H14N2O3 7.4
C7H14N2O3 7.4
C11H14O6 7.4
C15H20O 7.4
C7H14N2O3 7.4
1-piperidinecarbothioamide 7.4
C7H14N2O3 7.4
C7H14N2O3 7.4
C7H14N2O3 7.4
C7H14N2O3 7.4
C7H14N2O3 7.4
C7H14N2O3 7.4
14H-dibenzo[a,j]xanthene 7.4
C15H20O 7.4
C7H14N2O3 7.4
C7H14N2O3 7.4
C7H14N2O3 7.4
4-fluoro-2-methylphenol 7.4
C7H14N2O3 7.4
Cyasterone 7.4
C7H14N2O3 7.4
MEK 7.2
Deltonin 7.2
CLTC 6.9
NEU 6.9
C7H14N2O3 6.8
Nafoxidine hydrochloride 6.8
N-methyl-1-naphthamide 6.8
C7H14N2O3 6.8
4,6-pyrimidinediamine 6.8
Agnuside 6.8
4,6-pyrimidinediamine 6.8
C15H20O2 6.8
C7H14N2O3 6.8
Trifolirhizin 6.8
Proanthocyanidin A2 6.8
C24H32O4S 6.8
more...