Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:2.7.10.1 (ERK)
 95,504 document(s) hit in 31,850,051 MEDLINE articles (0.08 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
ERK 26251
EGFR 13873
HER2 11271
Mol 7521
MAPK 7296
tyrosine kinase 7100
Sep 5880
MEK 5878
p38 5454
PCL 5068
AKT 4790
ERK1 4665
JNK 4570
epidermal growth factor receptor 4537
PI3K 4331
MET 4235
KIT 4073
p53 3808
RET 3280
VEGFR2 3078
receptor tyrosine kinase 2991
BRAF 2757
ALK 2644
vascular endothelial growth factor 2495
FLT3 2438
mTOR 2431
cytokine 2373
VEGF 2119
KRAS 2058
anaplastic lymphoma kinase 1986
FGFR1 1884
estrogen receptor 1813
KDR 1700
EGF 1689
ERBB2 1676
neu 1665
epidermal growth factor 1606
caspase-3 1605
collagen 1603
insulin 1599
TNF 1519
PDGFR 1491
MAP kinase 1400
Bcl-2 1386
extracellular signal-regulated kinase 1350
IL-6 1350
MEK1 1313
mitogen-activated protein 1283
NET 1274
STAT3 1258
PTEN 1255
FGFR2 1247
PDGFRA 1197
FGFR3 1122
ATP 1109
EGF receptor 1039
VEGFR-1 1034
PIK3CA 1031
IGF1R 1020
CD34 1019
c-fms 1000
PKC 987
c-Jun 955
progesterone receptor 951
RAF 938
ERK2 930
cyclin D1 927
p21 914
phosphatidylinositol 3-kinase 871
catenin 865
E-cadherin 851
phosphatase 834
hepatocyte growth factor 832
c-kit 832
AP-1 826
PEG 824
erbB-2 814
Ki-67 807
tumor necrosis factor 805
lipopolysaccharide 802
MAP 797
vascular endothelial growth factor receptor 788
HER3 763
NRAS 761
proto-oncogene 751
ROS 743
CREB 738
PDGF 723
HEP 714
FGF 711
Raf-1 709
IL-8 697
tyrosine kinase receptor 696
platelet-derived growth factor 687
hormone receptor 686
ROS1 664
p65 658
LPS 654
PARP 639
platelet-derived growth factor receptor 617
NEP 608
MYC 605
lymphoid 604
fibronectin 603
vimentin 592
STAT 586
MMP-9 585
osteogenic 582
AXL 582
IFN 578
CD4 573
fused 569
NMR 567
threonine 566
FISH 556
histone 550
IRR 549
FAK 542
inducible nitric oxide synthase 540
NPM1 539
matrix metalloproteinase 538
COX-2 537
insulin-like growth factor 525
CD44 513
CDK4 504
CD117 503
brain-derived neurotrophic factor 502
CD8 496
chemokine 496
Vascular endothelial growth factor 495
c-fos 493
c-Met 488
extracellular signal-regulated kinase 1 483
JAK2 481
PKA 479
CD31 477
ACS 475
FGF receptor 475
HGF 475
mast cell 474
BRCA1 474
Rho 461
endoplasmic reticulum 452
p27 451
PD-L1 447
IL-10 443
TLR4 442
ACH 439
AML 437
tyrosine kinase 3 435
cage 427
RET proto-oncogene 427
EML4 427
neuregulin 424
proteasome 423
MMP-2 422
Met 422
protein kinase B 421
nodal 420
alkaline phosphatase 418
FGFR4 412
p16 409
TNF-alpha 405
EPH 403
CDKN2A 401
PDGFRB 397
phosphoinositide 3-kinase 395
gut 392
c-Myc 391
BCR 389
stem cell factor 389
ubiquitin 385
CXCR4 382
FGF2 382
ABL 378
insulin receptor 375
proliferating cell nuclear antigen 375
smooth muscle actin 375
STAT5 375
cyclooxygenase-2 373
ERBB 373
PTK 372
interferon 371
IDH1 368
PI3 367
c-Src 366
VEGFR-3 365
She 358
CCND1 357
ras 357
NTRK1 356
focal adhesion kinase 355
glycoprotein 350
TRK 349
TIF 347
caspase-9 347
CD45 347
NF1 345
cytochrome c 345
androgen receptor 340
CD30 337
ERBB3 336
A431 335
SRC 330
RhoA 329
P38 328
HER4 327
Epidermal growth factor receptor 326
macrophage colony-stimulating factor 324
SMA 322
kit 321
CSF1R 319
histone deacetylase 315
angiotensin II 314
RON 311
GTP 309
PLA 308
interleukin-6 308
nerve growth factor 306
MMP9 306
p42 305
aromatase 304
TEL 302
IL-4 302
MRI 301
caspase-8 301
AMPK 298
p44 297
p38MAPK 297
p38 MAP kinase 296
PLC 295
JNK1 294
IGF1 294
TGF-beta 294
IL-2 292
CD133 292
protein tyrosine kinase 292
AKT1 291
cyclin 291
GTPase 291
PD-1 288
MER 287
adaptor protein 287
IGF-1 286
BCL2 286
Poly 283
GSH 283
HRAS 282
vascular endothelial growth factor A 282
vascular endothelium 281
MDM2 281
NTRK3 280
Mcl-1 280
cyclin E 279
GSK 279
osteosarcoma 279
erythroid 278
Fibroblast growth factor 277
glial fibrillary acidic protein 277
ERBB4 275
AMP 271
B23 270
UTR 268
cytokeratin 267
vascular endothelial growth factor receptor 2 267
SHP-2 266
mucin 265
IRS-1 264
THP 264
TCR 262
CXCL12 262
membrane-bound 261
RANKL 259
survivin 257
glial cell line-derived neurotrophic factor 257
PTC 256
annexin V 255
ATPase 255
N-cadherin 253
Fas 253
nucleophosmin 249
ATM 249
RUNX1 249
Nrf2 249
p38 mitogen-activated protein kinase 248
APC 247
SEB 247
polypeptide 247
catalase 247
EMT 245
G protein-coupled receptor 245
calcitonin 244
desmin 244
IL-1 243
SOD 242
c-myc 242
PKB 241
CK5 240
beta-catenin 239
receptor kinase 238
neutral endopeptidase 238
BRCA2 237
ESR1 236
axonal 235
superoxide dismutase 234
hemoglobin 233
FLT1 231
INSR 231
CD56 231
amphiregulin 231
STAT1 229
TNM 229
CD11b 229
serine/threonine kinase 229
VEGF-C 228
S100 225
receptor protein tyrosine kinase 224
urokinase-type plasminogen activator 223
Sp1 223
Ang II 222
more...
Disease
cancer 25120
tumor 21111
breast cancer 10031
PCL 5083
lung cancer 3798
carcinoma 3663
tumor growth 3226
non-small cell lung cancer 3099
tumorigenesis 2910
metastases 2746
adenocarcinoma 2738
acute myeloid leukemia 2629
tumor progression 2047
leukemia 1874
melanoma 1852
colorectal cancer 1805
carcinogenesis 1584
hepatocellular carcinoma 1495
gastric cancer 1196
MCF 1193
squamous cell carcinoma 1173
glioblastoma 1120
lymphoma 1055
glioma 1048
metastatic breast cancer 1030
prostate cancer 964
lung carcinoma 913
stromal tumors 898
ovarian cancer 855
diabetes 834
gastrointestinal stromal tumor 813
Alzheimer's disease 757
colon cancer 753
medullary thyroid carcinoma 752
neuroblastoma 736
HEP 714
primary tumor 709
ischemia 702
multiple endocrine neoplasia 683
pancreatic cancer 673
anaplastic large cell lymphoma 669
hypertension 618
sarcoma 608
obesity 564
renal cell carcinoma 563
achondroplasia 546
chronic myeloid leukemia 526
aggressiveness 512
multiple myeloma 495
tumor angiogenesis 486
atherosclerosis 484
thyroid cancer 477
HGF 476
Leukemia 464
depression 456
HIV 448
psychopathy 440
bladder cancer 434
pheochromocytoma 428
papillary thyroid cancer 419
brain metastases 399
ABL 378
glioblastoma multiforme 369
ductal carcinoma 367
mastocytosis 364
liver cancer 349
ATM 345
brain tumor 340
stroke 333
acute lymphoblastic leukemia 327
cold 324
Hodgkin's disease 321
dysplasia 316
osteosarcoma 312
myelodysplastic syndrome 311
Blocking 309
asthma 305
MEN 2 303
Hippel 303
heart failure 303
rheumatoid arthritis 302
SEM 295
Parkinson's disease 292
GSH 284
B-cell lymphoma 283
epithelial ovarian cancer 281
WT1 280
pertussis 278
mammary tumor 276
small cell lung cancer 276
anemia 274
APC 269
type 2 diabetes 268
Melanoma 265
aggression 263
SCID 262
posttraumatic stress disorder 260
myeloproliferative disorders 254
ductal carcinoma in situ 250
solid tumor 249
leukemogenesis 247
EMT 245
cervical cancer 244
osteoporosis 244
craniosynostosis 240
liver metastases 233
liver cancer 229
Glioblastoma 227
myocardial infarction 226
acute promyelocytic leukemia 218
neutropenia 217
MEN 2B 217
addiction 214
eosinophilia 209
schizophrenia 207
Epstein 206
Luminal 206
arthritis 206
endometrial cancer 205
retinoblastoma 203
thalassemia 203
metastatic melanoma 202
sepsis 201
cardiovascular disease 197
infectious diseases 195
rash 194
sepsis 193
T-cell lymphoma 193
residual disease 193
fibrosarcoma 190
Hepatocellular carcinoma 187
adenoma 187
DM1 187
hyperglycemia 187
uterus 186
immunodeficiency 185
virus infection 184
skin cancer 184
chronic lymphocytic leukemia 181
influenza 177
osteoarthritis 176
herpes simplex 169
cognitive impairment 169
astrocytoma 164
lung metastases 164
acute leukemia 163
hematologic malignancies 161
bone metastases 160
head and neck cancer 158
mole 157
minimal residual disease 156
tumor initiation 154
preeclampsia 153
plaque 153
chronic lymphocytic leukemia 152
SDS 149
chronic obstructive pulmonary disease 148
NOD 148
colitis 147
Neuroblastoma 147
Neuroblastoma 147
esophageal cancer 146
AIDS 145
EMA 144
thrombocytopenia 143
neoplastic transformation 142
TEM 140
violence 138
cerebral ischemia 136
paraganglioma 135
liver fibrosis 135
TEM 133
renal cancer 132
rhabdomyosarcoma 132
adenocarcinoma of the lung 132
IMT 131
pneumonia 131
esophageal cancer 128
T-cell lymphomas 127
MTC 126
HCG 126
multiple sclerosis 125
coronary artery disease 125
neurofibromatosis type 1 125
atopic dermatitis 123
tuberculosis 122
dementia 122
tumor vasculature 121
non-Hodgkin's lymphoma 121
TAM 120
proteinuria 120
lymphatic vessels 119
systemic lupus erythematosus 117
PML 117
myocardial ischemia 117
NAME 115
Infection 115
neuroendocrine tumor 114
cirrhosis 113
DDP 112
inflammatory bowel disease 111
autism 111
mesothelioma 110
Apert syndrome 109
renal disease 108
medulloblastoma 106
lymphadenopathy 106
epilepsy 106
cornea 106
metabolic syndrome 106
Crouzon syndrome 105
psoriasis 104
autoimmune disease 102
myeloid leukemia 102
diabetic nephropathy 99
pulmonary fibrosis 98
HCC 97
oral cancer 97
infertility 96
hepatitis B 96
hepatitis C 96
invasive cancer 95
hyperparathyroidism 95
pruritus 94
Mycobacterium 93
SAR 93
Ewing's sarcoma 93
adult AML 93
rare disease 93
carcinoma in situ 93
MIP 91
cutaneous melanoma 91
chronic pain 90
carcinoma of the breast 90
leiomyosarcoma 89
pediatric AML 89
Best 88
neurofibromatosis 88
bacterial infection 88
PHA 88
genetic disorder 87
diabetic retinopathy 86
CAP 86
B-cell lymphomas 85
toxic shock syndrome 85
ATRX 85
mole 85
cystic fibrosis 84
Kaposi's sarcoma 84
macular degeneration 84
Thyroid cancer 83
mastocytoma 82
chronic myelomonocytic leukemia 81
Osteosarcoma 81
polycystic kidney 81
mantle cell lymphoma 81
Osteosarcoma 81
FAS 80
NF2 80
malaria 80
dermatitis 80
congestive heart failure 79
schistosomiasis 79
MEN1 79
rabies 78
carcinomatosis 78
mental illness 78
cardiomyopathy 77
amyotrophic lateral sclerosis 77
AGS 77
skin disease 76
neuroendocrine carcinoma 76
hypogonadotropic hypogonadism 76
hepatitis 76
MTS 75
trisomy 74
anaplastic thyroid cancer 74
leiomyoma 73
heart disease 73
mast cell leukemia 72
blindness 72
TCP 71
fatty liver 71
Huntington's disease 71
PDB 71
Adhesion 71
vascular disease 71
tuberous sclerosis 70
endometriosis 70
fits 70
liver disease 70
chronic eosinophilic leukemia 70
renal failure 69
HNSCC 69
stomatitis 69
brain cancer 67
CAM 67
lymphoblastic leukemia 67
developmental delay 67
childhood cancer 66
inflammatory breast cancer 66
West 65
cytomegalovirus 65
interstitial lung disease 65
PGA 64
major depressive disorder 64
mental retardation 64
mental retardation 64
lupus 64
T-cell acute lymphoblastic leukemia 64
AS1 63
peripheral neuropathy 63
periodontitis 63
fibromyalgia 63
ARF 62
Pfeiffer syndrome 62
chondrosarcoma 62
bipolar disorder 62
graft-versus-host disease 62
neuropathy 62
more...
Symptom
pain 701
diarrhea 388
fatigue 267
nausea 195
starvation 180
seizures 153
vomiting 137
headache 108
functional recovery 102
abdominal pain 99
anesthesia 87
weakness 77
cough 75
collapse 75
splenomegaly 73
dyspnea 72
overweight 68
anorexia 54
analgesia 53
exhaustion 48
respiratory distress 46
constipation 45
hypothermia 44
discomfort 43
discomfort 40
hyperoxia 38
erythema 37
anosmia 37
flushing 34
thinning 30
acidity 29
ataxia 28
back pain 28
dizziness 27
HSA 26
decreased appetite 25
tremor 24
asthenia 24
nausea and vomiting 24
memory loss 24
bone pain 24
chest pain 23
hepatosplenomegaly 22
chills 22
distraction 22
cachexia 22
arthralgia 22
Ill 21
skin damage 21
low back pain 21
shortness of breath 21
insomnia 20
hepatomegaly 19
angina 19
dry skin 18
epigastric pain 18
myalgia 17
hemoptysis 17
syncope 17
acute stress 14
Neuropathic pain 14
hypercapnia 14
Scratch 14
nipple discharge 14
agitation 14
nipple discharge 14
acute pain 11
fasciculation 11
Welt 11
skin irritation 11
exertional dyspnea 10
pelvic pain 10
orofacial pain 10
dysuria 10
night sweats 9
lethargy 9
pallor 9
cancer pain 8
wheezing 8
hunger 8
muscle cramps 8
abdominal discomfort 8
irregular bleeding 8
hypotonia 7
ENT 7
acute abdominal pain 7
hoarseness 7
chronic constipation 7
hopelessness 7
ACHE 7
acute abdomen 7
sore throat 7
paresis 7
DNA marker 7
stigma 6
dysarthria 6
dry eye 6
spasticity 6
polyuria 6
colic 6
despair 6
regurgitation 6
paraparesis 6
bloating 5
hip pain 5
tinnitus 5
vertigo 5
sleepiness 5
numbness 5
dystonia 5
Depressive symptoms 5
bradykinesia 5
menopausal symptoms 5
fever of unknown origin 5
neck pain 5
paresthesia 5
eds 4
spasm 4
Fluctuation 4
apathy 4
alexithymia 4
knee pain 4
peri-menopausal 4
periorbital edema 4
myoclonus 4
cerebellar ataxia 4
rhinorrhea 4
abnormal gait 3
Stiffness 3
hemiplegia 3
sneezing 3
blurred vision 3
stridor 3
POA 3
CSR 3
neurological disability 3
masculinization 3
body pain 3
microbial colonization 3
Burning 3
leg pain 3
general problem 3
hypertonia 3
neuralgia 3
flank pain 3
heartburn 3
productive cough 3
peau d'orange 3
lightheadedness 3
Gastrointestinal symptoms 3
cyanosis 3
frequent urination 2
loss of taste 2
hot flashes 2
Inflammatory pain 2
nasal discharge 2
hyperemesis gravidarum 2
chorea 2
hypoproteinemia 2
polydipsia 2
hot flushes 2
BHS 2
urinary frequency 2
tingling 2
dysesthesia 2
incoordination 2
Decreased activity 2
thigh pain 2
clubbing 2
abdominal fullness 2
facial pain 2
throat irritation 2
consciousness disturbance 2
chest tightness 2
skin irritant 2
anal pain 2
Wind 2
ophthalmoplegia 2
persistent cough 2
physical appearance 2
No adverse effect 2
limb pain 2
Cushingoid 2
rigors 2
generalized pain 2
wrist pain 2
Spotting 2
female puberty 2
Cushingoid 2
stomach pain 2
twitching 2
abdominal cramps 1
Respiratory abnormalities 1
disturbed balance 1
motor symptom 1
Oral pruritus 1
male subfertility 1
Anoxia 1
Respiratory symptoms 1
aphonia 1
snoring 1
Lhermitte's sign 1
startle reaction 1
acute low back pain 1
Skin symptoms 1
Visceral pain 1
tachypnea 1
Erythema annulare centrifugum 1
Beau's lines 1
High weight 1
onychomadesis 1
breast hyperplasia 1
testicular pain 1
dental pain 1
torticollis 1
Visual symptoms 1
hyperosmia 1
eye discharge 1
GI irritation 1
intestinal bleeding 1
catarrh 1
orthopnea 1
Sedation 1
Increased skin sensitivity 1
hypalgesia 1
photopsia 1
bedwetting 1
hyperemesis 1
physical symptom 1
forgetfulness 1
Joint hypermobility 1
emaciation 1
bitter taste 1
retracted nipple 1
enuresis 1
right upper quadrant pain 1
Intermenstrual bleeding 1
bigeminal 1
Motor dysfunction 1
Visual disturbances 1
impaired motor coordination 1
catatonia 1
stomach cramps 1
muscle rigidity 1
excessive sweating 1
chronic back pain 1
No toxic effect 1
Regurgitation 1
nasal congestion 1
neck stiffness 1
swollen joints 1
scaly skin 1
prominent nose 1
delayed language development 1
urethral discharge 1
difficulty with urination 1
unable to sleep 1
shoulder pain 1
chronic cough 1
Mills 1
Sore 1
Severe diarrhea 1
bladder pain 1
Buckling 1
pedal edema 1
arm pain 1
Flare 1
halitosis 1
rundown 1
Braxton Hicks contractions 1
loss of balance 1
Multimorbidity 1
Drug
ENT 1283
Herceptin 1075
MAP 878
ROS 738
Imatinib 483
Dermatol 449
CSF 359
Gefitinib 358
lysine 349
IL-2 293
Gleevec 267
PTC 257
Cetuximab 241
Sorafenib 233
IFN-gamma 215
Erlotinib 213
DM1 184
ETS 171
Bevacizumab 138
Monit 138
Cardiovasc 130
ICI 122
NVP 114
uPA 97
Gel 95
GEO 91
MTC 85
G-CSF 83
Angiotensin II 82
Taxol 82
Dasatinib 82
ROC 76
EE2 75
ascorbate 75
ABC 71
TEL 71
CAM 71
Pertuzumab 68
p75 68
Docetaxel 68
KGF 64
vitamin E 62
Leaf 61
Paraffin 60
MRC 57
Mutagen 56
Tarceva 56
PTH 55
CTX 51
caffeine 50
MDS 49
Vandetanib 48
CTC 45
Midostaurin 45
Asn 44
NADH 43
Activin 43
Heme 41
Everolimus 39
Panitumumab 39
Adriamycin 39
TAK 37
Asthma 37
Ethanol 37
TAT 37
CPT-11 36
Retinoic acid 36
Fulvestrant 35
ADM 35
ALA 33
Simvastatin 33
ADR 32
Arsenic trioxide 32
Gelatin 32
Nephron 31
Ouabain 30
anti-CD33 29
ETA 29
CCL 29
Estrogens 28
Indomethacin 28
Fluorescein 28
Bortezomib 28
RFP 28
PCP 27
Sunitinib malate 27
G418 27
nitroglycerin 26
CDX 26
Histamine 26
Pemetrexed 26
CTX 26
Albumin 26
CDX 26
Rituximab 25
CTX 25
IL-11 25
Tykerb 25
Norplant 24
lactose 24
TTC 24
Forskolin 23
Alliance 23
Nexavar 23
TAC 23
citric acid 23
DNase I 22
Nitric Oxide 22
IFN-beta 22
THF 21
NH3 21
Vitamin E 21
Growth hormone 21
CTC 21
Growth hormone 20
ampicillin 20
PDL 20
Taxotere 20
Glucagon 20
Axitinib 20
Alanine 19
Epigallocatechin 19
Lovastatin 19
Oxaliplatin 18
EPA 17
Emodin 17
DHT 17
TiO2 17
Emodin 17
DHT 17
Fluorescein 16
Portal 16
Itraconazole 16
ZnO 16
Dial 15
Spectrum 15
Vinorelbine 14
FAD 14
CoCl2 14
CoCl2 14
Irinotecan 14
Fragment 14
Glutathione 14
Vorinostat 13
Biopolymers 13
HCG 13
SiO2 13
Gastro 13
Check 13
Silica 12
Isotretinoin 12
Etoposide 12
HCH 12
PDGF B-chain 12
IL-1ra 12
Retinoic Acid 12
Cremophor EL 12
DEX 12
RAL 11
Rosiglitazone 11
Triclosan 11
BTC 11
Phosphoramidon 11
Doxycycline 11
PCB 11
Fraction 11
Vitamin A 11
Bayer 11
Ginseng 11
Troglitazone 11
CaCl2 10
Aloe 10
EML 10
Propofol 10
Ixabepilone 10
NBT 10
CaCl2 10
AMC 10
CaCl2 10
Myricetin 10
Photofrin 10
Raloxifene 10
Spectrum 10
ACT 10
VCR 10
R1881 9
niacin 9
Verteporfin 9
Tipifarnib 9
Zoledronic acid 9
Flavopiridol 9
Xeloda 9
Ranitidine 9
Depo-Provera 9
Dihydrotestosterone 9
balanced salt solution 9
DMAP 9
ID2 9
Glycyrrhiza 9
CPM 9
Pravastatin 9
K-252a 8
Norplant 8
Fentanyl 8
MDM 8
Artesunate 8
EPI 8
AraC 8
BLM 8
Gemzar 8
Nephron 8
L-tyrosine 7
Kenyan 7
Amiloride 7
Vatalanib 7
Scopolamine 7
Vitamin K 7
ISP 7
Parkin 7
GHRP 7
Parkin 7
DMI 7
NAG 7
Bosutinib 7
-deoxyadenosine 7
Meth 7
NOV 7
DEL 6
CED 6
Lestaurtinib 6
AZT 6
Captopril 6
CFS 6
Bifidobacterium 6
PFT 6
TRM 6
Hyaluronidase 6
Glide 6
3-Methyladenine 6
DPA 6
Tocopherol 6
Hyaluronidase 6
Gliclazide 6
CEC 6
Triad 6
Tacrolimus 6
AZT 6
Ipilimumab 6
Doyle 6
Ringer's solution 6
Idarubicin 6
Luteinizing 6
PE2 6
Phosphatidylserine 6
Amiloride 5
Trifluoperazine 5
ZnCl2 5
Clodronate 5
Imiquimod 5
Urokinase 5
Tannic acid 5
Cilostazol 5
Monensin 5
Kainic acid 5
AIC 5
BH4 5
Lenalidomide 5
Vitamin B12 5
ZnCl2 5
Allergen 5
Leucovorin 5
Rosuvastatin 5
Liraglutide 5
Atropine 5
Azithromycin 5
Navelbine 5
VCR 5
Motesanib 5
Serum albumin 5
Infliximab 4
2-Methoxyestradiol 4
Capsicum 4
Areca 4
CFT 4
Papaverine 4
Mevastatin 4
Indinavir 4
Alimta 4
Infliximab 4
RBT 4
NaI 4
CIA 4
Rutin 4
Bumetanide 4
Clofarabine 4
Thyroglobulin 4
CPZ 4
Prednisone 4
Compound 9 4
Theophylline 4
AGG 4
OIF 4
Zoledronic acid 4
Levonorgestrel 4
Camp 4
PPA 4
Fructose 4
MEA 4
9-THC 4
GRF 4
Salbutamol 4
NaI 4
NaI 4
Triad 4
Modafinil 4
TMS 4
Compound 19 4
Mubritinib 4
NaI 4
SMP 4
more...
Enzyme
ERK 95504
mitogen-activated protein kinase 16661
MEK 6869
focal adhesion kinase 3081
protein kinase 3041
protein kinase C 1847
caspase-3 1219
luciferase 980
phosphatidylinositol 3-kinase 871
MAP 799
CD10 738
PARP 697
ACS 476
proteasome 437
alkaline phosphatase 418
AMP-activated protein kinase 407
phosphoinositide 3-kinase 396
superoxide dismutase 364
AMPK 353
phospholipase C 353
cdc2 338
calcineurin 333
catalase 328
reverse transcriptase 306
GSK 304
AMPK 304
peroxidase 289
NADPH oxidase 288
RNA polymerase 277
ATPase 276
caspase-9 275
APC 273
NADPH oxidase 258
urokinase-type plasminogen activator 246
IKK 245
collagenase 241
MEKK1 224
caspase-8 223
glutathione S-transferase 208
thrombin 201
lactate dehydrogenase 189
trypsin 186
DAT 181
alanine aminotransferase 174
MMP 174
P-glycoprotein 160
CaMKII 149
NO synthase 147
PDK1 145
NOS 143
succinate dehydrogenase 141
topoisomerase 135
ACE 134
aspartate aminotransferase 131
topoisomerase 130
STK 127
succinyl-CoA synthetase 124
renin 117
phospholipase A2 115
adenylate cyclase 111
lipase 107
tyrosinase 104
CD13 104
thymidine kinase 103
tryptase 100
RNase 100
STK11 99
glutathione peroxidase 96
RNase 94
protein phosphatase 2A 94
tyrosine hydroxylase 93
transcriptase 92
MIP 90
neuraminidase 88
lysozyme 88
phosphodiesterase 85
acetylcholinesterase 81
DNA methyltransferase 78
plasmin 78
NQO1 77
DCF 76
granzyme B 73
MMP-3 72
cathepsin K 67
AST 66
phospholipase D 62
glyceraldehyde-3-phosphate dehydrogenase 61
MDR 61
PKG 60
GRK5 59
CEP 57
guanylate cyclase 54
CEP 54
matrix metalloproteinase 2 54
CYP3A4 53
matrix metalloproteinase 9 52
farnesyltransferase 50
beta-galactosidase 48
farnesyltransferase 48
heme oxygenase 48
GRK2 48
creatine kinase 47
demethylase 47
isocitrate dehydrogenase 47
caspase-1 46
isocitrate dehydrogenase 46
cathepsin B 45
aldehyde dehydrogenase 44
sphingosine kinase 44
sialidase 43
aldehyde dehydrogenase 43
myosin light chain kinase 43
matriptase 43
prostate-specific antigen 42
thymidylate synthase 42
cathepsin D 42
tissue plasminogen activator 41
MPP 40
TOR 40
thyroid peroxidase 39
aldehyde dehydrogenase 38
TACE 38
aldehyde dehydrogenase 38
elastase 38
aldehyde dehydrogenase 38
TAT 37
histone acetyltransferase 37
ALDH 37
complex I 35
firefly luciferase 35
CPT 35
acid phosphatase 35
caspase-7 34
caspase-7 34
CPT 33
arginase 33
ornithine decarboxylase 33
ribonuclease 33
CPT 33
chloramphenicol acetyltransferase 33
ribonuclease 33
matriptase 32
PTPase 32
endonuclease 31
neutrophil elastase 31
glyceraldehyde-3-phosphate dehydrogenase 30
kinesin 30
glutathione reductase 29
lipoxygenase 29
HK2 28
hyaluronidase 28
DNase 28
enolase 28
gamma-glutamyl transpeptidase 28
polo-like kinase 1 28
hexosaminidase 28
PCP 27
endothelin-converting enzyme 27
furin 27
thromboplastin 27
p80 27
xanthine oxidase 26
peroxiredoxin 26
thymidine phosphorylase 26
SPC 25
cholinesterase 25
HSD 25
dihydrofolate reductase 25
prolyl hydroxylase 25
transglutaminase 24
DNA polymerase 24
PAH 23
TdT 23
glyceraldehyde-3-phosphate dehydrogenase 23
prostate-specific membrane antigen 22
carbonic anhydrase 22
ribonucleotide reductase 22
hyaluronidase 22
monoamine oxidase 22
enterokinase 21
pepsin 21
diacylglycerol kinase 21
glyceraldehyde-3-phosphate dehydrogenase 21
glyceraldehyde-3-phosphate dehydrogenase 21
ATP synthase 21
hormone-sensitive lipase 20
inositol 3-kinase 20
lipoprotein lipase 20
gamma-glutamylcysteine synthetase 19
interstitial collagenase 19
chymotrypsin 19
ribonucleotide reductase 19
LPL 19
acetyl-CoA carboxylase 19
MTD 19
glucose-6-phosphate dehydrogenase 19
CAD 18
PAL 18
MDP 18
CAD 18
CAD 18
chymase 18
meprin 18
TSA 18
lysyl oxidase 18
kallikrein 18
phosphatidylinositol-4,5-bisphosphate 3-kinase 18
glutamine synthetase 17
choline acetyltransferase 17
pyruvate kinase 17
dihydropyrimidine dehydrogenase 17
heparinase 17
papain 17
ricin 17
glutaminase 17
TSP-1 16
hexokinase 16
phosphoenolpyruvate carboxykinase 16
indoleamine 2,3-dioxygenase 16
histone demethylase 16
sialyltransferase 16
CYP7A1 16
PGM 16
soluble epoxide hydrolase 16
sialyltransferase 16
m-calpain 16
aldose reductase 15
proteinase K 15
phosphofructokinase 15
sialyltransferase 15
insulin-degrading enzyme 15
rhodopsin kinase 15
apyrase 15
factor C 14
peptidylarginine deiminase 14
ubiquitin-protein ligase 14
dipeptidyl peptidase IV 14
chitinase 14
transketolase 14
sulfatase 14
fumarase 14
thermolysin 14
alcohol dehydrogenase 14
triphosphatase 14
Thy1 13
AGT 13
glucose oxidase 13
peptidyl-prolyl cis-trans isomerase 13
pyruvate dehydrogenase 13
mu-calpain 13
hepsin 13
hepsin 13
p100 13
phosphoribulokinase 12
cytosine deaminase 12
CPM 12
histidine decarboxylase 12
prostaglandin synthetase 12
histidine kinase 12
caspase-2 12
Alternating 12
urease 12
caspase-2 12
15-lipoxygenase 12
PDE 12
S1 nuclease 12
hypoxanthine-guanine phosphoribosyltransferase 12
carboxylesterase 12
CPS 12
phosphoglycerate kinase 11
HCS 11
CDR 11
microsomal epoxide hydrolase 11
micrococcal nuclease 11
phosphorylase 11
urease 11
AMP-activated kinase 11
tryptophan hydroxylase 10
adenosine deaminase 10
angiotensin-converting enzyme 2 10
PAM 10
BAL 10
prolidase 10
15-hydroxyprostaglandin dehydrogenase 10
dihydropyrimidine dehydrogenase 10
adenosine deaminase 10
3-hydroxy-3-methylglutaryl-CoA reductase 10
GAS 10
PST 10
phosphoenolpyruvate carboxykinase 9
phosphoenolpyruvate carboxykinase 9
thioredoxin reductase 9
caspase-6 9
ceruloplasmin 9
caspase-6 9
chondroitinase 9
cytochrome oxidase 9
inositol phosphatase 9
citrate synthase 9
MCS 9
SMP 8
asparaginase 8
cutinase 8
CLK1 8
PCE 8
NQO2 8
UDP-glucuronosyltransferase 8
SPT 8
proprotein convertase 8
MAT 8
12-lipoxygenase 8
subtilisin 8
pyruvate dehydrogenase 8
pyruvate dehydrogenase 8
eEF2 kinase 8
MAT 7
adenosine kinase 7
CPN 7
dopamine beta-hydroxylase 7
PRE 7
more...
Compound
DNA 7325
Dec 6419
MEK 5768
tyrosine 5536
methionine 4612
Clin 3636
oxygen 2420
calcium 1887
water 1583
TNF 1519
glucose 1327
PEG 1217
MDA 1202
MTT 1153
ATP 1112
serine 1104
PEG 1092
phosphate 947
cAMP 933
threonine 890
acetate 851
MAP 834
sodium 805
nitric oxide 780
HEP 714
cysteine 699
hydrogen 635
arginine 553
lysine 496
ACS 478
ACS 475
sulfate 457
retinoic acid 398
BCR 389
glutamate 389
alanine 386
ABL 385
leucine 375
Insulin 374
Phe 370
iron 359
ethanol 329
GTP 315
zinc 313
GSH 294
GSH 294
salt 286
iodine 282
urea 281
AMP 280
PMA 276
nitrogen 273
Asp 270
NH2 268
His 265
THP 264
THP 264
PLA 262
PMA 247
N-acetylcysteine 247
H2O2 245
potassium 242
Tyrosine 233
bromide 230
TNM 228
TIF 228
galactose 224
Luminal 211
pyrimidine 209
PGE 208
Cardiol 205
pyrimidine 203
Estrogen 195
Estrogen 195
COS 191
proline 183
TEM 182
DAT 181
Gly 179
5-HT 176
Curcumin 171
Pac 167
silver 166
CAM 164
Ang II 162
SDS 162
PGE2 161
Cbl 160
Thyroid 160
methanol 158
cGMP 151
quinazoline 149
quinazoline 149
creatinine 148
ADP 147
tryptophan 145
DDP 145
NMDA 143
copper 141
Adriamycin 137
ammonium 137
ADR 136
ADP 136
ADP 136
Vimentin 135
ASA 133
boron 130
glutamine 127
ICI 126
valine 126
5-FU 126
CO2 120
vitamin D 118
DSM 117
ATF 116
SEE 114
glycerol 114
Collagen 113
formaldehyde 111
ALP 110
hyaluronic acid 108
Angiotensin II 106
NAD 104
SCC 103
tryptophan 102
TPA 101
CAP 100
DFS 100
TPA 99
acetic acid 98
Paclitaxel 97
dUTP 97
aspartic acid 97
silicon 96
Rapamycin 95
tryptophan 94
tryptophan 94
DMSO 94
CAT 93
Panam 93
Tamoxifen 93
Tamoxifen 93
GABA 92
pyridine 92
CAT 91
glutamic acid 91
CAT 91
GABA 90
carbonate 90
Ile 90
aspartic acid 89
TOF 89
MTS 88
CAP 86
Hemoglobin 86
MTC 86
aspartic acid 85
cadmium 85
aspartic acid 84
NAD 83
aldosterone 83
ADP-ribose 82
fluorine 81
ammonia 81
Melatonin 80
titanium 79
NADPH 78
Metformin 78
NADPH 78
prostacyclin 78
Metformin 77
Phosphatidylinositol 76
PGA 75
Neuronal 75
Resveratrol 74
PEI 73
PEI 73
MDR 73
acrylamide 72
acetone 72
nicotinamide 71
selenium 71
TCP 71
TCP 71
TCP 71
TEL 71
TCP 71
COX 70
manganese 70
Wortmannin 69
vinyl 69
GDP 68
AMPA 68
Serine 68
noradrenaline 67
Histone 67
DPG 67
Estradiol 66
cobalt 65
DBA 65
SET 64
ENU 64
pyrene 64
Progesterone 64
aldehyde 63
Optimal 63
TSH 63
diacetate 62
hydroxide 61
quinoline 59
HCl 59
benzene 59
H2S 58
Thrombin 58
Pluronic 58
ethyl acetate 58
aldehyde 56
GlcNAc 56
Heparin 56
isopropanol 56
NEU 56
ACTH 55
Genistein 55
acetonitrile 55
nitrate 54
quinoline 54
DTPA 54
pyrrolidine 53
L-DOPA 53
anthracene 53
2-hydroxyethyl 53
chloroform 52
asparagine 51
Dopamine 51
nickel 51
2-hydroxyethyl 51
Docetaxel 51
2-hydroxyethyl 51
2-hydroxyethyl 51
CTX 51
2-hydroxyethyl 51
2-hydroxyethyl 51
Mg2+ 51
caffeine 51
2-hydroxyethyl 51
2-hydroxyethyl 51
GAP 51
TTC 50
LIN 50
phenol 50
BCG 49
APAP 49
pyrrolidine 48
PAS 48
CPT 48
DPPH 48
Hematoxylin 47
kaempferol 47
phosphorus 47
EDTA 47
EDTA 47
Dexamethasone 47
PVA 46
THF 46
MIA 46
Quercetin 46
PHB 46
palmitic acid 46
acridine 46
Heme 45
DMF 44
adenosylmethionine 43
acrylic acid 43
DCC 43
NADH 43
PDB 43
aluminum 42
homocysteine 42
2-oxoglutarate 42
Cereb 42
Luteolin 41
Cholesterol 41
pentose 40
pentose 40
pentose 40
pentose 40
MPP 40
MPP 40
Isoproterenol 40
chalcone 39
Sphingosine 38
GSSG 38
formic acid 38
formic acid 38
formic acid 38
formic acid 38
formic acid 38
TACE 38
formic acid 38
formic acid 38
formic acid 38
gallic acid 38
formic acid 38
formic acid 38
GMP 38
Berberine 38
Retinal 37
aniline 37
4-chlorophenyl 36
CPT-11 36
naphthoquinone 36
4-chlorophenyl 36
GalNAc 36
chromium 36
Leucine 36
H2S 36
naphthoquinone 35
naphthoquinone 35
BMC 35
dichloromethane 35
more...