Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: EC:2.7.10.1 (
ERK
)
95,504
document(s) hit in 31,850,051 MEDLINE articles (0.07 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
ERK
0.275
EGFR
0.145
HER2
0.105
PCL
0.053
MET
0.044
KIT
0.043
RET
0.034
MEK
0.028
ALK
0.028
FLT3
0.026
anaplastic lymphoma kinase
0.021
FGFR1
0.020
VEGFR2
0.020
KDR
0.018
MAPK
0.018
ERBB2
0.018
PDGFR
0.015
tyrosine kinase
0.015
JNK
0.013
NET
0.013
more...
Disease
PCL
0.052
HEP
0.007
tumor
0.007
breast cancer
0.007
cancer
0.006
non-small cell lung cancer
0.004
anaplastic large cell lymphoma
0.003
stromal tumors
0.002
gastrointestinal stromal tumor
0.002
achondroplasia
0.002
lung cancer
0.002
acute myeloid leukemia
0.002
tumor growth
0.002
medullary thyroid carcinoma
0.002
tumorigenesis
0.002
metastatic breast cancer
0.001
MEN 2
0.001
adenocarcinoma
0.001
MEN 2B
0.001
tumor progression
0.001
more...
Symptom
diarrhea
0.000
pain
0.000
nausea
0.000
fatigue
0.000
Increased skin sensitivity
0.000
Oral pruritus
0.000
starvation
0.000
anosmia
0.000
retracted nipple
0.000
functional recovery
0.000
vomiting
0.000
decreased appetite
0.000
Scratch
0.000
splenomegaly
0.000
Braxton Hicks contractions
0.000
nipple discharge
0.000
nipple discharge
0.000
dry skin
0.000
abdominal pain
0.000
skin damage
0.000
more...
Drug
Herceptin
0.005
ENT
0.002
Gefitinib
0.001
Imatinib
0.001
Cetuximab
0.001
Erlotinib
0.001
Gleevec
0.001
MAP
0.001
PTC
0.000
Sorafenib
0.000
Pertuzumab
0.000
Midostaurin
0.000
ROS
0.000
DM1
0.000
Vandetanib
0.000
Tarceva
0.000
MTC
0.000
NVP
0.000
Tykerb
0.000
Dasatinib
0.000
more...
Enzyme
ERK
1.000
mitogen-activated protein kinase
0.030
MEK
0.027
focal adhesion kinase
0.002
protein kinase
0.001
STK
0.001
MAP
0.001
protein kinase C
0.001
phosphatidylinositol 3-kinase
0.001
CD10
0.001
caspase-3
0.000
succinyl-CoA synthetase
0.000
PARP
0.000
MEKK1
0.000
phosphoinositide 3-kinase
0.000
luciferase
0.000
DAT
0.000
STK11
0.000
AMPK
0.000
cdc2
0.000
more...
Compound
MEK
0.027
HEP
0.007
methionine
0.004
tyrosine
0.003
TIF
0.002
MAP
0.001
DNA
0.001
MDA
0.001
MTT
0.000
TNF
0.000
PEG
0.000
PEG
0.000
ABL
0.000
BCR
0.000
DAT
0.000
NEU
0.000
Dec
0.000
serine
0.000
threonine
0.000
oxygen
0.000
more...