Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:2.7.10.1 (ERK)
 95,504 document(s) hit in 31,850,051 MEDLINE articles (0.08 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
ERK 26251
EGFR 13873
HER2 11271
Mol 7521
MAPK 7296
tyrosine kinase 7100
Sep 5880
MEK 5878
p38 5454
PCL 5068
AKT 4790
ERK1 4665
JNK 4570
epidermal growth factor receptor 4537
PI3K 4331
MET 4235
KIT 4073
p53 3808
RET 3280
VEGFR2 3078
more...
Disease
cancer 25120
tumor 21111
breast cancer 10031
PCL 5083
lung cancer 3798
carcinoma 3663
tumor growth 3226
non-small cell lung cancer 3099
tumorigenesis 2910
metastases 2746
adenocarcinoma 2738
acute myeloid leukemia 2629
tumor progression 2047
leukemia 1874
melanoma 1852
colorectal cancer 1805
carcinogenesis 1584
hepatocellular carcinoma 1495
gastric cancer 1196
MCF 1193
more...
Symptom
pain 701
diarrhea 388
fatigue 267
nausea 195
starvation 180
seizures 153
vomiting 137
headache 108
functional recovery 102
abdominal pain 99
anesthesia 87
weakness 77
collapse 75
cough 75
splenomegaly 73
dyspnea 72
overweight 68
anorexia 54
analgesia 53
exhaustion 48
more...
Drug
ENT 1283
Herceptin 1075
MAP 878
ROS 738
Imatinib 483
Dermatol 449
CSF 359
Gefitinib 358
lysine 349
IL-2 293
Gleevec 267
PTC 257
Cetuximab 241
Sorafenib 233
IFN-gamma 215
Erlotinib 213
DM1 184
ETS 171
Monit 138
Bevacizumab 138
more...
Enzyme
ERK 95504
mitogen-activated protein kinase 16661
MEK 6869
focal adhesion kinase 3081
protein kinase 3041
protein kinase C 1847
caspase-3 1219
luciferase 980
phosphatidylinositol 3-kinase 871
MAP 799
CD10 738
PARP 697
ACS 476
proteasome 437
alkaline phosphatase 418
AMP-activated protein kinase 407
phosphoinositide 3-kinase 396
superoxide dismutase 364
phospholipase C 353
AMPK 353
more...
Compound
DNA 7325
Dec 6419
MEK 5768
tyrosine 5536
methionine 4612
Clin 3636
oxygen 2420
calcium 1887
water 1583
TNF 1519
glucose 1327
PEG 1217
MDA 1202
MTT 1153
ATP 1112
serine 1104
PEG 1092
phosphate 947
cAMP 933
threonine 890
more...