Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:2.7.1.21 (thymidine kinase)
7,561 document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
thymidine kinase 7478
Mol 850
Sep 503
DNA polymerase 298
fused 258
glycoprotein 215
thymidylate synthase 166
Gen 165
polypeptide 163
Thymidine kinase 144
ATP 143
p53 140
cytokine 119
deoxycytidine kinase 115
ribonucleotide reductase 112
TK1 109
thymidylate synthetase 109
interferon 97
endonuclease 91
thymidine phosphorylase 84
ornithine decarboxylase 80
DNase I 75
HAT 74
thymidylate kinase 72
dihydrofolate reductase 71
estrogen receptor 70
growth hormone 69
Sp1 68
lymphoid 64
insulin 64
AMP 63
CAT 63
nuclear protein 59
hypoxanthine-guanine phosphoribosyltransferase 59
alkaline phosphatase 58
c-myc 57
osteosarcoma 57
phosphorylating 54
TK2 53
DNA polymerase alpha 51
more...
Disease
herpes simplex 3226
tumor 1358
cancer 1268
suicide 653
herpes 293
vaccinia 283
glioma 220
varicella 215
tumor growth 214
cytomegalovirus 210
lymphoma 192
hepatocellular carcinoma 191
carcinoma 189
leukemia 189
plaque 180
HIV 160
Epstein 132
breast cancer 123
immunodeficiency 122
melanoma 98
virus infection 92
AIDS 88
metastases 87
glioblastoma 83
infectious diseases 81
CEM 77
Infection 76
adenocarcinoma 73
prostate cancer 70
brain tumor 66
carcinogenesis 65
colon cancer 63
MCF 61
graft-versus-host disease 59
osteosarcoma 59
mammary tumor 55
latent infection 52
lung cancer 51
hepatitis B 50
Rous sarcoma 49
more...
Symptom
starvation 19
diarrhea 16
pain 12
seizures 7
splenomegaly 5
respiratory distress 4
anorexia 4
hyperoxia 4
HSA 4
functional recovery 4
anesthesia 3
ophthalmoplegia 3
flushing 3
lethargy 3
weakness 2
Fluctuation 2
hepatomegaly 2
erythema 2
hypothermia 2
vomiting 2
neuralgia 2
skin irritation 2
agitation 2
nausea 2
collapse 1
eye discharge 1
chills 1
cerebellar ataxia 1
exertional dyspnea 1
wheezing 1
back pain 1
tonic-clonic seizure 1
decreased appetite 1
discomfort 1
discomfort 1
colic 1
POA 1
bone pain 1
hemiplegia 1
arthralgia 1
more...
Drug
DNase I 78
Ganciclovir 74
G418 69
Acyclovir 67
AZT 66
AZT 66
Gel 59
IL-2 35
PMEA 34
CSF 34
Mutagen 27
IFN-gamma 26
Dermatol 23
lysine 21
HPMPC 18
PFA 17
MRC 13
ICI 11
ampicillin 10
caffeine 10
ROS 9
IFN-beta 9
THF 8
CDP 8
AC2 8
-deoxyadenosine 8
Asn 8
EE2 8
Retinoic acid 8
AraC 7
Bifidobacterium 6
ddI 6
Leaf 6
Norplant 6
TAT 5
Zovirax 5
G-CSF 5
Etoposide 4
TFT 4
Deoxyadenosine 4
more...
Enzyme
thymidine kinase 7561
DNA polymerase 344
thymidylate synthase 264
chloramphenicol acetyltransferase 243
luciferase 234
beta-galactosidase 150
ribonucleotide reductase 121
deoxycytidine kinase 119
ribonucleotide reductase 112
cytosine deaminase 106
ERK 103
protein kinase 91
endonuclease 91
thymidine phosphorylase 85
thymidylate kinase 80
ornithine decarboxylase 80
hypoxanthine-guanine phosphoribosyltransferase 74
reverse transcriptase 74
dihydrofolate reductase 73
catalase 70
firefly luciferase 69
RNA polymerase 66
alkaline phosphatase 58
uridine kinase 54
lactate dehydrogenase 54
DNase 44
galactokinase 37
S1 nuclease 35
adenosine deaminase 35
adenosine deaminase 35
deoxyguanosine kinase 34
protein kinase C 34
ATPase 34
topoisomerase 28
RNase 28
Dm-dNK 27
RNase 26
invertase 25
5'-nucleotidase 25
dihydropyrimidine dehydrogenase 25
more...
Compound
DNA 2512
Dec 548
pyrimidine 237
pyrimidine 237
phosphate 196
Clin 163
TTP 152
ATP 144
TMP 111
calcium 97
uridine 95
acetate 86
AZT 80
water 80
cAMP 78
sodium 75
retinoic acid 66
Thymidine 66
Acyclovir 65
glucose 64
CAT 63
CAT 63
CAT 63
COS 53
zinc 49
MTT 47
AMP 47
dCTP 46
methionine 44
PPA 37
sulfate 35
alanine 35
d4T 34
oxygen 34
tryptophan 34
BUdR 33
arginine 32
dATP 32
hydrogen 32
5-FU 31
more...