Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: EC:2.7.1.21 (
thymidine kinase
)
7,561
document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
thymidine kinase
7478
Mol
850
Sep
503
DNA polymerase
298
fused
258
glycoprotein
215
thymidylate synthase
166
Gen
165
polypeptide
163
Thymidine kinase
144
ATP
143
p53
140
cytokine
119
deoxycytidine kinase
115
ribonucleotide reductase
112
TK1
109
thymidylate synthetase
109
interferon
97
endonuclease
91
thymidine phosphorylase
84
ornithine decarboxylase
80
DNase I
75
HAT
74
thymidylate kinase
72
dihydrofolate reductase
71
estrogen receptor
70
growth hormone
69
Sp1
68
lymphoid
64
insulin
64
AMP
63
CAT
63
nuclear protein
59
hypoxanthine-guanine phosphoribosyltransferase
59
alkaline phosphatase
58
c-myc
57
osteosarcoma
57
phosphorylating
54
TK2
53
DNA polymerase alpha
51
more...
Disease
herpes simplex
3226
tumor
1358
cancer
1268
suicide
653
herpes
293
vaccinia
283
glioma
220
varicella
215
tumor growth
214
cytomegalovirus
210
lymphoma
192
hepatocellular carcinoma
191
carcinoma
189
leukemia
189
plaque
180
HIV
160
Epstein
132
breast cancer
123
immunodeficiency
122
melanoma
98
virus infection
92
AIDS
88
metastases
87
glioblastoma
83
infectious diseases
81
CEM
77
Infection
76
adenocarcinoma
73
prostate cancer
70
brain tumor
66
carcinogenesis
65
colon cancer
63
MCF
61
graft-versus-host disease
59
osteosarcoma
59
mammary tumor
55
latent infection
52
lung cancer
51
hepatitis B
50
Rous sarcoma
49
more...
Symptom
starvation
19
diarrhea
16
pain
12
seizures
7
splenomegaly
5
respiratory distress
4
anorexia
4
hyperoxia
4
HSA
4
functional recovery
4
anesthesia
3
ophthalmoplegia
3
flushing
3
lethargy
3
weakness
2
Fluctuation
2
hepatomegaly
2
erythema
2
hypothermia
2
vomiting
2
neuralgia
2
skin irritation
2
agitation
2
nausea
2
collapse
1
eye discharge
1
chills
1
cerebellar ataxia
1
exertional dyspnea
1
wheezing
1
back pain
1
tonic-clonic seizure
1
decreased appetite
1
discomfort
1
discomfort
1
colic
1
POA
1
bone pain
1
hemiplegia
1
arthralgia
1
more...
Drug
DNase I
78
Ganciclovir
74
G418
69
Acyclovir
67
AZT
66
AZT
66
Gel
59
IL-2
35
PMEA
34
CSF
34
Mutagen
27
IFN-gamma
26
Dermatol
23
lysine
21
HPMPC
18
PFA
17
MRC
13
ICI
11
ampicillin
10
caffeine
10
ROS
9
IFN-beta
9
THF
8
CDP
8
AC2
8
-deoxyadenosine
8
Asn
8
EE2
8
Retinoic acid
8
AraC
7
Bifidobacterium
6
ddI
6
Leaf
6
Norplant
6
TAT
5
Zovirax
5
G-CSF
5
Etoposide
4
TFT
4
Deoxyadenosine
4
more...
Enzyme
thymidine kinase
7561
DNA polymerase
344
thymidylate synthase
264
chloramphenicol acetyltransferase
243
luciferase
234
beta-galactosidase
150
ribonucleotide reductase
121
deoxycytidine kinase
119
ribonucleotide reductase
112
cytosine deaminase
106
ERK
103
protein kinase
91
endonuclease
91
thymidine phosphorylase
85
thymidylate kinase
80
ornithine decarboxylase
80
hypoxanthine-guanine phosphoribosyltransferase
74
reverse transcriptase
74
dihydrofolate reductase
73
catalase
70
firefly luciferase
69
RNA polymerase
66
alkaline phosphatase
58
uridine kinase
54
lactate dehydrogenase
54
DNase
44
galactokinase
37
S1 nuclease
35
adenosine deaminase
35
adenosine deaminase
35
deoxyguanosine kinase
34
protein kinase C
34
ATPase
34
topoisomerase
28
RNase
28
Dm-dNK
27
RNase
26
invertase
25
5'-nucleotidase
25
dihydropyrimidine dehydrogenase
25
more...
Compound
DNA
2512
Dec
548
pyrimidine
237
pyrimidine
237
phosphate
196
Clin
163
TTP
152
ATP
144
TMP
111
calcium
97
uridine
95
acetate
86
AZT
80
water
80
cAMP
78
sodium
75
retinoic acid
66
Thymidine
66
Acyclovir
65
glucose
64
CAT
63
CAT
63
CAT
63
COS
53
zinc
49
MTT
47
AMP
47
dCTP
46
methionine
44
PPA
37
sulfate
35
alanine
35
d4T
34
oxygen
34
tryptophan
34
BUdR
33
arginine
32
dATP
32
hydrogen
32
5-FU
31
more...