Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:2.7.1.21 (thymidine kinase)
 7,561 document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
thymidine kinase 7478
Mol 850
Sep 503
DNA polymerase 298
fused 258
glycoprotein 215
thymidylate synthase 166
Gen 165
polypeptide 163
Thymidine kinase 144
ATP 143
p53 140
cytokine 119
deoxycytidine kinase 115
ribonucleotide reductase 112
thymidylate synthetase 109
TK1 109
interferon 97
endonuclease 91
thymidine phosphorylase 84
ornithine decarboxylase 80
DNase I 75
HAT 74
thymidylate kinase 72
dihydrofolate reductase 71
estrogen receptor 70
growth hormone 69
Sp1 68
insulin 64
lymphoid 64
CAT 63
AMP 63
hypoxanthine-guanine phosphoribosyltransferase 59
nuclear protein 59
alkaline phosphatase 58
c-myc 57
osteosarcoma 57
phosphorylating 54
TK2 53
DNA polymerase alpha 51
glucocorticoid receptor 50
thyroid hormone 50
c-fos 49
AP-1 49
interleukin-2 48
uridine kinase 48
LTK 46
beta-globin 45
IFN 41
metallothionein 40
proliferating cell nuclear antigen 39
lactate dehydrogenase 38
CD8 38
thymus 38
galactokinase 37
albumin 37
histone 37
VEGFR-1 36
IL-2 35
erythroid 35
adenosine deaminase 35
thymidine kinase-1 35
colon carcinoma 35
alpha-fetoprotein 34
deoxyguanosine kinase 34
CD4 33
glial fibrillary acidic protein 33
tumor necrosis factor 33
caspase-3 33
collagen 31
transactivator 30
NMR 30
p21 30
carcinoembryonic antigen 30
DNase 29
IL-4 29
TMP 28
IFN-gamma 28
ara 27
ras 27
androgen receptor 27
epidermal growth factor 27
ATPase 26
beta 2-microglobulin 25
osteocalcin 25
prolactin 25
granulocyte 25
Raji 25
uridine phosphorylase 24
dCMP deaminase 24
HLA 24
GM-CSF 24
pol 23
connexin 23
HPRT 23
RNA polymerase II 23
telomerase reverse transcriptase 23
transcriptional activator 23
MRI 23
thymidine kinase 2 22
reductase 22
tyrosine kinase 22
PRL 22
ADP 22
c-Jun 22
thyroid hormone receptor 22
5'-nucleotidase 22
granulocyte-macrophage colony-stimulating factor 21
DNA-binding domain 21
CSF 21
RNase 21
transcriptional repressor 21
interferon-gamma 20
DNA-binding protein 20
alpha 4 20
dUTPase 20
cytochrome P450 20
surface antigen 20
TTP 20
prostate-specific antigen 20
zinc finger 20
SDS 19
TAT 19
TNF 19
progesterone receptor 19
GAL4 19
vascular endothelial growth factor 19
cyclin A 19
Pol 19
vitamin D receptor 18
beta-actin 18
cyclin 18
Duffy 18
Polymerase 17
cage 17
major histocompatibility complex 17
Bcl-2 17
connexin 43 17
CTP 17
CD38 17
purine nucleoside phosphorylase 17
CD34 16
mutant p53 16
PC-3 16
interleukin-6 16
EBP 16
hexokinase 16
proto-oncogene 16
Fas 16
IL-6 16
E2F1 15
alpha, beta 15
AP1 15
thyroglobulin 15
LDH 15
nuclear receptor 15
all-trans 15
dihydropyrimidine dehydrogenase 15
pyruvate kinase 14
carp 14
more...
Disease
herpes simplex 3226
tumor 1358
cancer 1268
suicide 653
herpes 293
vaccinia 283
glioma 220
varicella 215
tumor growth 214
cytomegalovirus 210
lymphoma 192
hepatocellular carcinoma 191
carcinoma 189
leukemia 189
plaque 180
HIV 160
Epstein 132
breast cancer 123
immunodeficiency 122
melanoma 98
virus infection 92
AIDS 88
metastases 87
glioblastoma 83
infectious diseases 81
CEM 77
Infection 76
adenocarcinoma 73
prostate cancer 70
brain tumor 66
carcinogenesis 65
colon cancer 63
MCF 61
graft-versus-host disease 59
osteosarcoma 59
mammary tumor 55
latent infection 52
lung cancer 51
hepatitis B 50
Rous sarcoma 49
chronic lymphocytic leukemia 48
SCID 46
encephalitis 46
sarcoma 45
multiple myeloma 44
ACV 42
ovarian cancer 42
gliosarcoma 41
neuroblastoma 39
retinoblastoma 39
colorectal cancer 38
glioblastoma multiforme 38
HSV infection 35
Adenovirus 33
tumorigenesis 30
chronic lymphocytic leukemia 30
pancreatic cancer 30
squamous cell carcinoma 29
Aujeszky's disease 28
gastric cancer 28
embryonal carcinoma 28
laryngotracheitis 27
lung carcinoma 26
acute myeloid leukemia 25
stomatitis 24
keratitis 24
Hodgkin's disease 24
bladder cancer 23
uterus 22
mesothelioma 22
TTP 21
herpes zoster 21
African swine fever 21
Kaposi's sarcoma 21
Leukemia 21
TTP 20
cold 20
epithelial ovarian cancer 20
tumor progression 20
SDS 19
ischemia 19
influenza 19
pituitary tumor 18
erythroleukemia 18
primary tumor 18
fibrosarcoma 18
liver cancer 17
cornea 17
depression 17
genital herpes 16
liver cancer 16
non-Hodgkin's lymphoma 15
Tumour necrosis 15
choriocarcinoma 15
hepatitis 15
hematologic malignancies 15
Burkitt's lymphoma 14
anemia 14
renal cell carcinoma 14
Varicella zoster 14
cowpox 14
Plaque 14
solid tumor 14
smallpox 13
liver metastases 13
malnutrition 12
DBA 12
residual disease 12
teratoma 12
Newcastle disease 12
non-small cell lung cancer 11
Liver regeneration 11
acute lymphoblastic leukemia 11
cholera 11
B-cell lymphoma 11
medulloblastoma 11
ATM 11
Mycoplasma 11
carcinomatosis 11
cirrhosis 11
Mycobacterium 11
respiratory disease 11
malignant mesothelioma 11
pheochromocytoma 10
diabetes 10
papilloma 10
diphtheria 10
brain cancer 10
hepatitis C 10
head and neck cancer 10
lung metastases 10
tuberculosis 9
esophageal cancer 9
tumor angiogenesis 9
small cell lung cancer 9
Glioblastoma 9
myopathy 9
viremia 9
esophageal cancer 9
rabies 9
lymphoproliferative disorders 8
chronic myeloid leukemia 8
thyroid cancer 8
acute promyelocytic leukemia 8
EBV infection 8
oral cancer 8
skin disease 8
genital infection 8
ocular herpes 8
PHA 8
thrombocytopenia 8
medullary thyroid carcinoma 8
NOD 8
ICP 8
stroke 8
gastroenteritis 8
mantle cell lymphoma 7
endometrial cancer 7
dysplasia 7
lymphoblastic leukemia 7
more...
Symptom
starvation 19
diarrhea 16
pain 12
seizures 7
splenomegaly 5
anorexia 4
HSA 4
functional recovery 4
respiratory distress 4
hyperoxia 4
flushing 3
anesthesia 3
lethargy 3
ophthalmoplegia 3
neuralgia 2
nausea 2
weakness 2
agitation 2
erythema 2
Fluctuation 2
hypothermia 2
hepatomegaly 2
vomiting 2
skin irritation 2
collapse 1
eye discharge 1
chills 1
cerebellar ataxia 1
exertional dyspnea 1
wheezing 1
back pain 1
tonic-clonic seizure 1
decreased appetite 1
discomfort 1
discomfort 1
colic 1
POA 1
bone pain 1
hemiplegia 1
arthralgia 1
breast hyperplasia 1
oliguria 1
incoordination 1
sleepiness 1
cachexia 1
penile lesion 1
syncope 1
memory loss 1
peri-menopausal 1
fatigue 1
Purulent nasal discharge 1
tachypnea 1
rhinorrhea 1
analgesia 1
abdominal pain 1
sneezing 1
acidity 1
ataxia 1
swollen joints 1
Drug
DNase I 78
Ganciclovir 74
G418 69
Acyclovir 67
AZT 66
AZT 66
Gel 59
IL-2 35
CSF 34
PMEA 34
Mutagen 27
IFN-gamma 26
Dermatol 23
lysine 21
HPMPC 18
PFA 17
MRC 13
ICI 11
caffeine 10
ampicillin 10
IFN-beta 9
ROS 9
-deoxyadenosine 8
THF 8
Asn 8
AC2 8
EE2 8
Retinoic acid 8
CDP 8
AraC 7
Norplant 6
Bifidobacterium 6
ddI 6
Leaf 6
Zovirax 5
TAT 5
G-CSF 5
PPA 4
Etoposide 4
TFT 4
DHT 4
MAP 4
CPT-11 4
Forskolin 4
MDS 4
Deoxyadenosine 4
nitroglycerin 4
CTX 3
Cytidine 3
ABC 3
TTC 3
Cidofovir 3
Valganciclovir 3
Silica 3
Ethanol 3
Ara-A 3
Estrogens 3
ROC 3
Adriamycin 3
CaCl2 2
CaCl2 2
uPA 2
Arsenic trioxide 2
PTC 2
CCL 2
Secretin 2
p75 2
Glycerol 2
DHT 2
ascorbate 2
Growth hormone 2
Glide 2
Kenyan 2
Reserpine 2
TAC 2
Growth hormone 2
L-tyrosine 2
Lobucavir 2
CaCl2 2
lactose 2
Photofrin II 2
Aztec 2
Photofrin 2
Cardiovasc 2
PMPA 2
PTH 2
GEO 2
Monit 2
Tenofovir 2
Rituximab 1
ENT 1
FSH-beta 1
Spectrum 1
Phosphatidylserine 1
Vitamin B12 1
Herceptin 1
Carbazeran 1
Tacrolimus 1
KAN 1
ACT 1
Pemetrexed 1
Sodium dichloroacetate 1
ADR 1
Eniluracil 1
Trifluoperazine 1
Carbetimer 1
Irinotecan 1
Raloxifene 1
Fluorescein 1
Albumin 1
NOV 1
ATV 1
PCB 1
vitamin E 1
Sulpiride 1
NADH 1
Leucovorin 1
Ranitidine 1
Emodin 1
Docetaxel 1
Prednisone 1
Meth 1
Orphan 1
Casodex 1
AVC 1
5-Iododeoxyuridine 1
beta-Galactosidase 1
Bevacizumab 1
Tannic acid 1
Taxol 1
Gramicidin 1
Vitamin A 1
Ginseng 1
Furan 1
BLM 1
Adenosine triphosphate 1
ETS 1
Asthma 1
Glutathione 1
Filgrastim 1
RFP 1
Pronase 1
Hivid 1
Advexin 1
FSH-beta 1
Sodium phenylbutyrate 1
ZnCl2 1
Sorafenib 1
Aminoguanidine 1
R1881 1
5-Fluorouridine 1
Spectrum 1
Alanine 1
DPA 1
Adenosine deaminase 1
Lenograstim 1
Sodium nitroprusside 1
Eniluracil 1
Foscavir 1
ZnCl2 1
more...
Enzyme
thymidine kinase 7561
DNA polymerase 344
thymidylate synthase 264
chloramphenicol acetyltransferase 243
luciferase 234
beta-galactosidase 150
ribonucleotide reductase 121
deoxycytidine kinase 119
ribonucleotide reductase 112
cytosine deaminase 106
ERK 103
endonuclease 91
protein kinase 91
thymidine phosphorylase 85
ornithine decarboxylase 80
thymidylate kinase 80
hypoxanthine-guanine phosphoribosyltransferase 74
reverse transcriptase 74
dihydrofolate reductase 73
catalase 70
firefly luciferase 69
RNA polymerase 66
alkaline phosphatase 58
uridine kinase 54
lactate dehydrogenase 54
DNase 44
galactokinase 37
S1 nuclease 35
adenosine deaminase 35
adenosine deaminase 35
ATPase 34
protein kinase C 34
deoxyguanosine kinase 34
RNase 28
topoisomerase 28
Dm-dNK 27
RNase 26
invertase 25
dihydropyrimidine dehydrogenase 25
5'-nucleotidase 25
dCMP deaminase 25
dihydropyrimidine dehydrogenase 24
caspase-3 24
topoisomerase 23
sucrase 23
aspartate aminotransferase 22
alanine aminotransferase 21
uracil phosphoribosyltransferase 20
prostate-specific antigen 20
mitogen-activated protein kinase 20
uridine phosphorylase 19
IMP dehydrogenase 18
orotate phosphoribosyltransferase 18
succinyl-CoA synthetase 18
STK 18
adenine phosphoribosyltransferase 17
phosphoenolpyruvate carboxykinase 17
phosphodiesterase 17
dUTPase 17
phosphoenolpyruvate carboxykinase 17
hexokinase 16
purine nucleoside phosphorylase 16
glucose-6-phosphate dehydrogenase 15
alpha-glucosidase 15
glutathione S-transferase 15
focal adhesion kinase 14
gamma-glutamyl transpeptidase 14
phosphoglycerate kinase 14
tyrosine aminotransferase 14
pyruvate kinase 14
nucleoside phosphotransferase 13
adenylate kinase 13
cytidine deaminase 12
phosphoenolpyruvate carboxykinase 12
deaminase 12
acid phosphatase 12
collagenase 11
P-glycoprotein 11
peroxidase 11
tyrosinase 11
aspartate transcarbamylase 10
renin 10
PARP 10
adenylate cyclase 10
neuraminidase 10
cdc2 10
lysozyme 10
arginase 9
beta-glucuronidase 9
DNA ligase 9
DNA ligase 9
RNase P 9
trypsin 9
carboxylesterase 9
superoxide dismutase 9
adenosine kinase 9
MEK 8
APC 8
malate dehydrogenase 8
deoxyribonuclease 8
deoxyadenosine kinase 8
deoxyribonuclease 8
guanylate kinase 8
urokinase-type plasminogen activator 7
phosphorylase 7
xanthine oxidase 7
prostate-specific membrane antigen 7
orotidine-5'-phosphate decarboxylase 7
AMPK 7
deoxycytidine deaminase 7
proteasome 7
AST 7
thrombin 7
caspase-9 7
caspase-8 7
phospholipase C 7
lactase 6
prolyl hydroxylase 6
calcineurin 6
TdT 6
cathepsin D 6
tyrosine hydroxylase 6
MMP-3 6
BMT 6
phosphoserine phosphatase 6
nucleotidase 6
S-adenosylmethionine decarboxylase 6
DNA methyltransferase 6
proline oxidase 6
ACS 5
tissue plasminogen activator 5
PRE 5
glyceraldehyde-3-phosphate dehydrogenase 5
aldehyde dehydrogenase 5
transcriptase 5
NQO1 5
creatine kinase 5
glyceraldehyde-3-phosphate dehydrogenase 5
alcohol dehydrogenase 5
MDR 5
transglutaminase 5
glutamine synthetase 5
PDK1 5
ribonuclease 5
N-acetyltransferase 5
ribonuclease 5
TAT 5
glyceraldehyde-3-phosphate dehydrogenase 4
glyceraldehyde-3-phosphate dehydrogenase 4
ornithine aminotransferase 4
GAS 4
CTP synthase 4
AMP deaminase 4
glyceraldehyde-3-phosphate dehydrogenase 4
glutathione peroxidase 4
UMP kinase 4
CPS 4
chymotrypsin 4
glucokinase 4
thromboplastin 4
more...
Compound
DNA 2512
Dec 548
pyrimidine 237
pyrimidine 237
phosphate 196
Clin 163
TTP 152
ATP 144
TMP 111
calcium 97
uridine 95
acetate 86
AZT 80
water 80
cAMP 78
sodium 75
retinoic acid 66
Thymidine 66
Acyclovir 65
glucose 64
CAT 63
CAT 63
CAT 63
COS 53
zinc 49
MTT 47
AMP 47
dCTP 46
methionine 44
PPA 37
sulfate 35
alanine 35
tryptophan 34
d4T 34
oxygen 34
BUdR 33
dATP 32
hydrogen 32
arginine 32
MDA 31
5-FU 31
phosphonoacetic acid 31
tyrosine 30
iodine 30
DEAE 29
dGTP 29
TMP 29
EMS 29
bromide 28
cadmium 28
galactose 28
TMP 28
TMP 28
ADP 25
pyrene 25
leucine 25
PEG 24
lysine 24
ADP 22
Thyroid 22
ADP 22
SDS 22
dUMP 22
serine 21
His 21
dUTP 21
fluorine 21
cysteine 20
vitamin D 20
TNF 19
threonine 19
ammonium 18
DHPG 18
CTP 17
iron 17
5-FC 17
DBA 16
boron 16
glycerol 16
TDP 16
salt 16
creatinine 15
GTP 15
Asp 15
glutamine 15
copper 14
Uridine 14
urea 14
Mg2+ 14
Insulin 14
Dexamethasone 13
GMP 13
DMSO 13
TPA 13
Guo 13
TSH 13
TPA 13
nitrogen 12
1,2-dimethylhydrazine 12
potassium 12
DBA 12
3TC 12
Neo 12
DBA 12
Ara-C 12
ethanol 11
tryptophan 11
tryptophan 11
aspartic acid 11
tryptophan 11
ICI 11
NH2 11
proline 11
caffeine 10
aspartic acid 10
PEG 10
asparagine 10
glutamate 10
PMEA 10
anthracene 10
ammonia 10
A 3 10
methyl methanesulfonate 10
PMA 10
Hydroxyurea 10
Cycloheximide 9
TCA 9
Ara-C 9
aspartic acid 9
FUDR 9
Trifluorothymidine 9
cGMP 9
aspartic acid 9
TRH 9
A 1 8
methanol 8
nitric oxide 8
CDP 8
ACTH 8
silver 8
acetic acid 8
Methotrexate 8
vinyl 8
Ile 8
Phe 8
dCMP 8
Estradiol 8
TEM 7
dihydrofolate 7
PGA 7
methane 7
IDU 7
PRPP 7
PMA 7
ZD1694 7
Foscarnet 7
Tamoxifen 7
Deoxycytidine 7
Tamoxifen 7
acrylamide 7
more...