Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: EC:2.7.1.21 (
thymidine kinase
)
7,561
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
Thyroid hormone dependent transcription stimulatory and inhibitory elements exist at the 5'-end of the rat GH (rGH) gene (TSE and
TIE
, respectively). In this study, the location of the sequences essential for TSE activity was examined using stably transfected GC cells. Because the
TIE
may influence TSE activity, we investigated TSE activity both on the rGH promoter, in the presence of the
TIE
, and on the viral
thymidine kinase
promoter, with the
TIE
deleted. The results of these studies indicate that the minimum sequences essential for TSE activity exist between positions -194 and -169 of the rGH gene.
...
PMID:Sequences essential for activity of the thyroid hormone responsive transcription stimulatory element of the rat growth hormone gene. 284 60
