Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts: Gene/Protein Disease Symptom Drug Enzyme Compound   Target Concepts: Gene/Protein Disease Symptom Drug Enzyme Compound

---

Query: EC:2.7.1.137 (phosphatidylinositol 3-kinase)
11,064 document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .

Human Gene/Protein phosphatidylinositol 3-kinase 11014 insulin 1767 Mol 1252 AKT 1094 protein kinase B 1077 mTOR 1035 Sep 776 tyrosine kinase 649 p85 635 p38 627 IRS-1 608 extracellular signal-regulated kinase 597 ERK1 568 MAPK 538 ERK 533 insulin receptor 515 PI3K 487 PI3 480 MEK 444 cytokine 427 more...

Disease cancer 1723 tumor 1225 breast cancer 412 diabetes 338 tumorigenesis 281 tumor growth 213 carcinoma 213 ischemia 206 pertussis 197 leukemia 185 carcinogenesis 181 obesity 181 hepatocellular carcinoma 177 type 2 diabetes 171 prostate cancer 151 tumor progression 148 Alzheimer's disease 146 hypertension 124 MCF 123 neuroblastoma 118 more...

Symptom starvation 124 pain 42 diarrhea 30 seizures 29 functional recovery 16 collapse 13 anesthesia 12 ataxia 8 nausea 8 exhaustion 7 fatigue 6 cachexia 6 weakness 6 hyperoxia 6 respiratory distress 6 analgesia 5 cerebellar ataxia 5 splenomegaly 5 cough 4 anorexia 4 more...

Drug IL-2 69 MAP 62 NVP 49 CSF 48 lysine 45 ICI 36 ROS 36 Angiotensin II 35 IFN-gamma 35 Dermatol 29 caffeine 28 Cardiovasc 26 Herceptin 16 Asn 15 Growth hormone 14 Taxol 14 Heme 14 Glucagon 14 p75 14 Growth hormone 14 more...

Enzyme phosphatidylinositol 3-kinase 11064 mitogen-activated protein kinase 2598 protein kinase 1283 protein kinase C 872 ERK 871 MEK 688 focal adhesion kinase 650 phospholipase C 349 caspase-3 342 GSK 256 luciferase 166 AMP-activated protein kinase 141 calcineurin 132 NO synthase 122 proteasome 92 NADPH oxidase 91 superoxide dismutase 91 PDK1 85 ATPase 82 NADPH oxidase 82 more...

Compound tyrosine 1482 glucose 961 DNA 885 Dec 833 Insulin 547 calcium 498 oxygen 478 serine 422 MEK 417 threonine 344 phosphate 311 nitric oxide 305 Wortmannin 289 cAMP 260 ATP 210 Clin 208 acetate 184 sodium 178 Phe 139 arginine 138 more...

---